Target list

Search results for query: Weighted union of Tgon queries

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  • Score for genes in query #41 (Tgon in Coccidia (5 species - 4 cryptosporiadia, 1 Neospora)): 25
  • Score for genes in query #33 (Tgon modbase): 30
  • Score for genes in query #39 (Tgon in all apicomplexa (12 species - 6 plasmodia, 4 cryptosporidia, 1 Neospora, 1 babesia)): 75
  • Score for genes in query #32 (Tgon PDB structure): 50
  • Score for genes in query #29 (Tgon all proteins): 1
  • Score for genes in query #27 (Tgon any EC number): 99
  • Score for genes in query #40 (Tgon not in human): 25
  • Score for genes in query #35 (Tgon any essentiality): 50
  • Score for genes in query #30 (Tgon dindex >=0.6): 35
  • Score for genes in query #37 (Tgon assayable): 35
  • Score for genes in query #34 (Tgon Mwt <100K): 20
  • Score for genes in query #38 (Tgon Pubmed): 35
  • Score for genes in query #31 (Tgon no TM domain): 20

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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7014 records found | Showing page 1 of 281 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. gondii   TGME49_256760   OG5_126685   pyruvate kinase PyK1 440
T. gondii   TGME49_224900   OG5_126762   adenylate kinase, putative 425
T. gondii   TGME49_217580   OG5_128634   DNA-directed RNA polymerase III RPC6 425
T. gondii   TGME49_310700   OG5_126821   serine/threonine phosophatase PP1 425
T. gondii   TGME49_249180   OG5_127385   bifunctional dihydrofolate reductase-thymidylate synthase 395
T. gondii   TGME49_263070   OG5_126901   CMGC kinase, CK2 family 395
T. gondii   TGME49_309730   OG5_126785   thioredoxin reductase 390
T. gondii   TGME49_219800   OG5_127061   vacuolar ATP synthase subunit b, putative 390
T. gondii   TGME49_217890   OG5_126593   alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen, putativ ... 390
T. gondii   TGME49_265330   OG5_126888   cell-cycle-associated protein kinase GSK, putative 390
T. gondii   TGME49_240590   OG5_127455   DNA-directed RNA polymerase II RPB5 390
T. gondii   TGME49_225050   OG5_127233   adenosylhomocysteinase, putative 390
T. gondii   TGME49_218220   OG5_126712   cell-cycle-associated protein kinase CDK, putative 390
T. gondii   TGME49_309210   OG5_126593   peroxiredoxin 6, putative 390
T. gondii   TGME49_249270   OG5_127741   protein disulfide isomerase-related protein (provisional), putative 390
T. gondii   TGME49_224490   OG5_127590   polyprenyl synthetase superfamily protein 390
T. gondii   TGME49_233720   OG5_127936   DNA-directed RNA polymerase II RPBABC8 390
T. gondii   TGME49_270780   OG5_127345   DNA-directed RNA polymerase II RPB6 390
T. gondii   TGME49_286210   OG5_127639   protein phosphatase 4, catalytic subunit 390
T. gondii   TGME49_263870   OG5_128638   glutamate-tRNA ligase 380
T. gondii   TGME49_225260   OG5_126637   DNA-directed RNA polymerase II RPB1 370
T. gondii   TGME49_313180   OG5_128795   cell-cycle-associated protein kinase PRP4, putative 370
T. gondii   TGME49_238190   OG5_127622   DNA-directed RNA polymerase II RPB3 360
T. gondii   TGME49_256970   OG5_127237   vacuolar ATP synthase subunit A, putative 360
T. gondii   TGME49_267390   OG5_127819   DNA-directed RNA polymerase I RPAC1 360

Showing page 1 (records 1-25) of 281