Target list

Search results for query: top-100 of ranked list for PLOS-NTD; Posted List 361, No tissue-differential gene expression data

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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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98 records found | Showing page 1 of 4 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product
B. malayi   Bm1_07670   OG5_127581   cytochrome C-type heme lyase
B. malayi   Bm1_19045   OG5_127028   acyl carrier protein, mitochondrial precursor, putative
B. malayi   Bm1_39715   OG5_126623   Endoplasmin precursor
B. malayi   Bm1_48865   OG5_126846   Csnk2b protein
B. malayi   Bm1_10270   OG5_127730   T-complex protein 1, beta subunit
B. malayi   Bm1_17890   OG5_127832   T-complex protein 1, delta subunit
B. malayi   Bm1_40505   OG5_127729   ube2i2 protein
B. malayi   Bm1_44725   OG5_127514   GTP-binding nuclear protein RAN/TC4
B. malayi   Bm1_17330   OG5_126927   succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
B. malayi   Bm1_53535   OG5_126799   alanyl-tRNA synthetase family protein
B. malayi   Bm1_30470   OG5_130454   Protein kinase domain containing protein
B. malayi   Bm1_31860   OG5_176445   immunodominant antigen homologue
B. malayi   Bm1_50780   OG5_176454   valyl-tRNA synthetase family protein
B. malayi   Bm1_50960   OG5_127237   vacuolar ATP synthase catalytic subunit A, osteoclast isoform
B. malayi   Bm1_44630   OG5_126812   oxidoreductase, short chain dehydrogenase/reductase family protein
B. malayi   Bm1_31140   OG5_175065   hypothetical protein
B. malayi   Bm1_17325   OG5_126927   succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
B. malayi   Bm1_41310   OG5_126677   Sars1 protein
B. malayi   Bm1_44415   OG5_192700   Neurotransmitter-gated ion-channel ligand binding domain containing protein
B. malayi   Bm1_39250   OG5_126843   protein disulphide isomerase
B. malayi   Bm1_16810   OG5_126595   actin
B. malayi   Bm1_10280   OG5_126720   transketolase
B. malayi   Bm1_18515   OG5_126841   ADP,ATP carrier protein, heart/skeletal muscle isoform T1
B. malayi   Bm1_41830   OG5_126799   Alanyl-tRNA synthetase
B. malayi   Bm1_28935   OG5_126843   transglutaminase