Detailed view for TcCLB.503909.84

Basic information

TDR Targets ID: 35733
Trypanosoma cruzi, calpain-like cysteine peptidase, putative
Source Database / ID:  TriTrypDB  GeneDB

pI: 6.138 | Length (AA): 1030 | MW (Da): 116144 | Paralog Number: 1

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG5

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00648   Calpain family cysteine protease
PF01067   Calpain large subunit, domain III

Gene Ontology

Mouse over links to read term descriptions.
GO:0005622   intracellular  
GO:0004198   calcium-dependent cysteine-type endopeptidase activity  
GO:0006508   proteolysis  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

There are 10 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
26 155 1io0 (A) 180 312 15.00 0.000017 1 0.55 -2.09
233 650 1df0 (A) 9 394 26.00 0.0000000015 1 0.25 0.81
246 844 1qxp (A) 21 609 21.00 0 1 0.55 0.51
254 611 1mdw (A) 29 344 22.00 0 0.96 0.43 -0.21
4 158 4per (A) 0 170 32.00 0.0019 1 0.373985 -0.16
31 157 1io0 (A) 185 314 15.00 0 1 0.484301 -1.65
233 764 1qxp (A) 9 548 23.00 0 1 0.489505 0.97
358 610 2r9f (A) 147 353 33.00 0 0.69 0.276131 0.86
615 746 2qfe (A) 688 811 23.00 0 0.35 0.305155 -0.23
749 890 2qfe (A) 681 811 21.00 0.000047 0.37 0.289564 -0.31

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

Upregulation Percent Ranking Stage Dataset
Mid 40-60% percentile epimastigote, metacyclic. Smircich P
Show/Hide expression data references
  • Smircich P Ribosome profiling reveals translation control as a key mechanism generating differential gene expression in Trypanosoma cruzi.

Orthologs

Ortholog group members (OG5_148117)

Species Accession Gene Product
Leishmania braziliensis LbrM.30.1980   calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative
Leishmania donovani LdBPK_302040.1   calpain-like cysteine peptidase, putative
Leishmania infantum LinJ.30.2040   calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative
Leishmania major LmjF.30.2040   calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative
Leishmania mexicana LmxM.29.2040   calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative
Trypanosoma brucei gambiense Tbg972.6.3100   calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative
Trypanosoma brucei Tb927.6.3310   cysteine peptidase, Clan CA, family C2, putative
Trypanosoma congolense TcIL3000_6_2860   cysteine peptidase, Clan CA, family C2, putative
Trypanosoma cruzi TcCLB.511507.70   cysteine peptidase, Clan CA, family C2, putative
Trypanosoma cruzi TcCLB.503909.84   calpain-like cysteine peptidase, putative

Essentiality

TcCLB.503909.84 has one or more orthologs with essentiality data
Gene/Ortholog Organism Phenotype Source Study
Tb927.6.3310 Trypanosoma brucei no significant loss or gain of fitness in bloodstream forms (3 days) alsford
Tb927.6.3310 Trypanosoma brucei significant gain of fitness in bloodstream forms (6 days) alsford
Tb927.6.3310 Trypanosoma brucei no significant loss or gain of fitness in procyclic forms alsford
Tb927.6.3310 Trypanosoma brucei no significant loss or gain of fitness in differentiation of procyclic to bloodstream forms alsford
Show/Hide essentiality data references
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model

Ranking Plot

Putative Drugs List

Compound Raw Global Species
0.0619 0.2706 0.2706
0.0339 0.2831 1
0.0459 0.295 0.3584
0.1927 0.271 0.271
0.025 0.5307 0.5307
0.0453 0.4995 0.5467
0.0476 0.2712 0.2712
0.1079 0.3194 0.3194
0.028 0.2675 0.2675
0.091 0.2901 0.2901
0.2232 0.3652 0.365
0.1124 0.2971 0.4261
0.0754 0.295 0.295
0.0465 0.4278 0.5307
0.0693 0.3125 0.3074
0.1881 0.4058 0.4056
0.081 0.3027 0.3026
0.1085 0.2529 0.2529
0.0476 0.3385 0.6454
0.0239 0.2663 0.2611
0.0455 0.3528 0.6355
0.0501 0.3381 0.3555
0.0331 0.3362 0.3571
0.056 0.5515 0.5477
0.1164 0.3108 0.3103
0.0517 0.3847 0.8567
0.055 0.5518 0.5516
0.0336 0.2606 0.751
0.0223 0.2855 0.2964
0.0284 0.3362 0.4405
0.0567 0.6334 0.6334
0.1065 0.5466 0.5459
0.0502 0.553 0.551
0.0474 0.5545 0.5535
0.0906 0.2947 0.2937
0.0653 0.341 0.341
0.0752 0.3323 1
0.0137 0.3118 0.8262
0.0066 0.2823 1
0.110659 0.558484 0.554216
0.0167 0.2996 1
0.0689 0.6464 0.8702
0.0488 0.4835 0.5535
0.0507 0.3911 0.5827
0.0555 0.2876 0.3484
0.0915 0.2625 0.2623
0.1065 0.4035 0.5546
0.0465 0.5396 0.537
0.011 0.2831 0.7689
0.0963 0.2979 0.2972
0.1287 0.2885 0.2872
0.0453 0.3062 0.6887
0.0049 0.2831 1
0.0265 0.2612 0.2984
0.1018 0.5466 0.5459
0.0667 0.6554 0.8377
0.14 0.2835 0.2834
0.0932 0.2893 0.2893
0.0442 0.2612 0.2612
0.0861 0.2755 0.2755
0.0442 0.2694 0.2694
0.0276 0.3494 1
0.101 0.5466 0.5459
0.0562 0.3393 0.3955
0.0518 0.5497 0.5497
0.0382 0.2614 0.5477
0.0062 0.2831 1
0.0947 0.2812 0.2807
0.0947 0.2812 0.2807
0.0482 0.5477 0.5477
0.0639 0.7102 0.8025
0.1209 0.2723 0.272
0.0296 0.2755 0.4845
0.1054 0.2897 0.2896
0.1207 0.2985 0.2704
0.0928 0.2707 0.2705
0.1065 0.4035 0.5546
0.056 0.275 0.3225
0.1103 0.3734 0.3728
0.0504 0.5831 0.5827
0.0567 0.6334 0.6334
0.1745 0.2696 0.2691
0.0752 0.3323 1
0.101 0.4051 0.5558
0.054 0.5517 0.5516
0.1083 0.259 0.2878
0.192 0.2693 0.2693
0.0508 0.5459 0.5459
0.0218 0.3334 1
0.1565 0.3908 0.3901
0.125 0.2586 0.2503
0.02 0.2764 0.4279
0.0454 0.5381 0.5307
0.0702 0.3864 0.3856
0.0462 0.4851 0.5518
0.0049 0.2831 1
0.027 0.2767 0.2767
0.2684 0.3582 0.3581
0.126 0.2844 0.2838
0.0288 0.3186 0.3619
0.0425 0.3261 0.9914
0.05 0.2651 0.2717
0.0457 0.2719 1
0.036 0.5479 0.5479
0.0254 0.5459 0.5459
0.0836 0.2948 0.2948
0.0469 0.549 0.5486
0.0459 0.2579 0.5307
0.0574247 0.541437 0.541437
0.0892 0.2779 0.277
0.1419 0.2938 0.4154
0.103 0.2555 0.3432
0.048 0.3094 0.5431
0.0763 0.3018 0.3014
0.0493 0.5827 0.5827
0.0749 0.3123 0.3121
0.0469 0.5477 0.5477
0.104 0.3444 0.399
0.1165 0.3662 0.3662
0.0324 0.3319 1
0.0186 0.3319 1
0.0893 0.2783 0.2777
0.0459 0.2579 0.5307
0.159 0.4361 0.5034
0.0523 0.5831 0.5827
0.0371 0.3512 1
0.1021 0.2869 0.2864
0.0586 0.2951 0.2951
0.0363 0.2834 0.2829
0.0331 0.2548 0.3578
0.0947 0.2812 0.2807
0.0489 0.382 0.5472
0.0575 0.4344 0.5827
0.0478 0.4821 0.5432
0.091 0.2901 0.2901
0.009 0.2831 1
0.0278 0.2842 0.3102
0.0509 0.5483 0.5516
0.1424 0.2595 0.2595
0.0457 0.4494 0.5433
0.0563 0.6532 0.653
0.0148 0.2612 1
0.0489 0.382 0.5472
0.0992 0.505 0.9306
0.0802 0.4002 0.3997
0.0998 0.2833 0.2833
0.0505 0.2831 1
0.056 0.5377 0.5333
0.0062 0.2831 1
0.0418 0.2828 0.2739
0.0482 0.5486 0.5486
0.1065 0.4035 0.5546
0.0493 0.5302 0.542
0.0452 0.2891 0.5307
0.0533 0.279 0.5586
0.0484 0.2878 0.3259
0.0547 0.2835 0.5827
0.0062 0.2831 1
0.0802 0.3277 0.7317
0.0861 0.2637 0.2637
0.0756 0.268 0.268
0.0829 0.416 0.415
0.0528 0.5486 0.5486
0.0215 0.2552 0.2301
0.4272 0.3168 0.3167
0.0418 0.3551 1
0.015 0.3288 0.9671
0.1129 0.5466 0.5459
0.0395 0.3319 0.6171
0.1304 0.3448 0.3844
0.0476 0.2831 1
0.0505 0.2831 1
0.1304 0.3448 0.3844
0.0549 0.5486 0.5486
0.0283 0.3069 0.3038
0.0519 0.5545 0.5535
0.0667 0.6545 0.7174
0.092 0.2681 0.2483
0.0131 0.2759 0.2733
0.1304 0.3448 0.3844
0.0838 0.3822 0.3822
0.0084 0.3169 1
0.0505 0.539 0.5375
0.113 0.4884 0.5715
0.0526 0.5406 0.5516
0.0595 0.3567 0.576
0.0989 0.4083 0.4082
0.0842 0.2795 0.2794
0.353 0.3139 0.3132
0.0045 0.2831 1
0.0878 0.2695 0.2691
0.0521 0.276 0.2741
0.0958 0.3094 0.3088
0.1326 0.2574 0.2574
0.0547 0.2835 0.5827
0.0543 0.5477 0.5477
0.0303 0.2606 1
0.0155 0.3243 0.9795
0.0971 0.3156 0.3145
0.0465 0.5486 0.5486
0.3462 0.2945 0.2944
0.0756 0.268 0.268
0.1031 0.2701 0.4909
0.0456 0.5518 0.5516
0.0306 0.3235 0.4884
0.0667 0.542 0.5925
0.126 0.2844 0.2838
0.0534 0.279 0.2771
0.1543 0.2911 0.2909
0.0165 0.2818 0.3789
0.1623 0.3141 0.3497
0.1374 0.2779 0.2779
0.0811 0.4057 0.5568
0.1894 0.2731 0.273
0.1457 0.3404 0.3509
0.0341 0.3105 1
0.0622 0.6448 0.8083
0.0902 0.3005 0.3005
0.1623 0.3141 0.3497
0.0501 0.3122 0.3101
0.0482 0.2659 0.537
0.0515 0.5842 0.5827
0.0504 0.5441 0.544
0.0563 0.5843 0.5827
0.2232 0.3652 0.365
0.0667 0.542 0.5925
0.0023 0.2562 1
0.058 0.5843 0.6337
0.097 0.3909 0.591
0.0598 0.6506 0.6505
0.0942528 0.558557 0.554216
0.0531 0.5842 0.5827
0.0631 0.6735 0.6735
0.0414 0.3402 0.6485
0.1065 0.4051 0.5558
0.1854 0.4304 0.4319
0.046 0.3127 0.3288
0.0739 0.2964 0.59
0.1447 0.3223 0.3338
0.142 0.2885 0.2883
0.0099 0.268 1
0.101 0.5466 0.5459
0.1079 0.3194 0.3194
0.0944 0.3059 0.3053
0.017 0.2831 0.4901
0.1881 0.4058 0.4056
0.0475 0.3151 0.544
0.097 0.3909 0.591
0.1121 0.5466 0.5459
0.0832 0.3029 0.3029
0.0474 0.4954 0.544
0.1623 0.3141 0.3497
0.0474 0.2726 0.9405
0.0368 0.3285 1
0.0478 0.3343 0.5566
0.0817 0.2726 0.2721
0.1141 0.3024 0.3014
0.0218 0.3332 1
0.0466 0.5545 0.5535
0.0545 0.5518 0.5516
0.0453 0.4995 0.5467
0.1252 0.2776 0.417
0.1881 0.4058 0.4056
0.0279 0.2779 0.3303
0.0752 0.3323 1
0.0283 0.3014 0.8492
0.0478 0.4969 0.5546
0.0549 0.5477 0.5477
0.0526 0.5317 0.5516
0.1717 0.3562 0.3945
0.0484 0.2878 0.3259
0.0102 0.2709 0.2709
0.144 0.2834 0.2833
0.0358 0.2822 0.3634
0.0584 0.2805 0.2984
0.0882 0.2857 0.2929
0.0414 0.3402 0.6485
0.1243 0.2529 0.2527
0.1543 0.2911 0.2909
0.257 0.2886 0.2886
0.0876 0.2669 0.299
0.0667 0.6554 0.8377
0.1019 0.2504 0.6822
0.0509 0.5477 0.5477
0.0038 0.301 1
0.0181 0.3224 1
0.0931 0.3519 0.7618
0.0967 0.49 0.4888
0.0499 0.5486 0.5486
0.0256 0.3119 0.6706
0.1085 0.2529 0.2529
0.0878 0.2658 0.2645
0.0175 0.3224 1
0.0122 0.3217 0.7789
0.0482 0.5486 0.5486
0.0498 0.5001 0.5477
0.0449 0.512 0.5546
0.023 0.3072 1
0.0982 0.2619 0.4715
0.0395 0.3319 0.6171
0.0476 0.5477 0.5477
0.0555 0.3348 0.5459
0.0567 0.6334 0.6334
0.0555 0.6504 0.6504
0.1464 0.2964 0.3879
0.0518 0.5477 0.5477
0.183 0.2782 0.2782
0.0538 0.5486 0.5486
0.1186 0.4773 0.5025
0.0807 0.2719 0.2715
0.0541 0.5518 0.5516
0.0724 0.2895 0.2895
0.0419 0.3001 0.4638
0.0449 0.5486 0.5486
0.1275 0.2761 0.2761
0.0489 0.382 0.5472
0.0455 0.5441 0.544
0.0837 0.3073 0.9198
0.0992 0.2609 0.5044
0.1266 0.427 0.427
0.1097 0.2995 0.2891
0.0827 0.3532 0.6341
0.0342 0.2856 1
0.1097 0.2995 0.2891
0.0456 0.5518 0.5516
0.1133 0.5477 0.5465
0.1141 0.3024 0.3014
0.028 0.2675 0.2675
0.1399 0.3196 0.331
0.0303 0.3482 0.5373
0.0752 0.3323 1
0.1623 0.3141 0.3497
0.1073 0.4994 0.8998
0.0343 0.2521 0.2961
0.0567 0.6334 0.6334
0.0257 0.2895 0.2755
0.068 0.6719 0.744
0.0605 0.5946 0.5943
0.1768 0.2753 0.2835
0.0489 0.5545 0.5535
0.0181 0.3224 1
0.0752 0.3323 1
0.1036 0.2882 0.2877
0.0619 0.6576 0.6576
0.0652 0.3012 0.3012
0.0752 0.3323 1
0.0627 0.2602 0.2598
0.045 0.5486 0.5486
0.1019 0.2504 0.6822
0.1167 0.2723 0.2715
0.0222 0.2527 1
0.0325 0.2599 1
0.0505 0.2831 1
0.1545 0.4029 0.4209
0.0141 0.3279 0.4704
0.0756 0.268 0.268
0.0347 0.2606 1
0.0109 0.3511 1
0.0215 0.3177 0.8458
0.0536 0.358 0.5827
0.101 0.4051 0.5558
0.344 0.2792 0.2792
0.047 0.3783 0.5336
0.056 0.5441 0.544
0.0947 0.2778 0.2772
0.2232 0.3652 0.365
0.0539 0.5402 0.5391
0.0876 0.2669 0.299
0.0531 0.3226 0.5883
0.1906 0.2745 0.2745
0.0752 0.3323 1
0.0193 0.2831 1
0.0045 0.2831 1
0.0414 0.3402 0.6485
0.0832 0.3029 0.3029
0.2232 0.3652 0.365
0.0824 0.5808 0.5933
0.0554 0.2897 0.3571
0.0527 0.546 0.5541
0.0893 0.4983 0.5424
0.05 0.5844 0.5844
0.0931 0.3519 0.7618
0.0752 0.3323 1
0.0455 0.3528 0.6355
0.0022 0.2562 1
0.0567 0.3464 0.3445
0.0992 0.2609 0.5044
0.097 0.3909 0.591
0.0466 0.5486 0.5486
0.1407 0.4121 0.4121
0.14 0.2835 0.2834
0.103 0.2555 0.3432
0.0035 0.2579 1
0.0181 0.3224 1
0.0457 0.2719 1
0.0453 0.4995 0.5467
0.056 0.2513 0.5411
0.1299 0.3064 0.3038
0.1065 0.5466 0.5459
0.0852 0.6092 0.7903
0.0697 0.65 0.8651
0.0478 0.3343 0.5566
0.1393 0.2729 0.4212
0.0813 0.5275 0.8907
0.1065 0.5466 0.5459
0.025 0.5377 0.5327
0.0942528 0.558557 0.554216
0.0343 0.2521 0.2961
0.0487 0.5179 0.5437
0.0756 0.268 0.268
0.1447 0.2842 0.284
0.0184 0.3402 0.4054
0.1129 0.5466 0.5459
0.1121 0.5477 0.5466
0.0852 0.6092 0.7903
0.0752 0.3323 1
0.0192 0.2831 1
0.0478 0.3343 0.5566
0.0565 0.3497 0.5827
0.0635 0.6933 0.8144
0.0349 0.2856 1
0.0993 0.2663 0.2662
0.0181 0.3224 1
0.0581 0.4687 0.7687
0.1073 0.5466 0.5459
0.0122 0.2729 0.8733
0.0947 0.2812 0.2807
0.1191 0.3013 0.3013
0.0971 0.2972 0.2965
0.045 0.5536 0.5516
0.0457 0.4494 0.5433
0.0962 0.5466 0.5459
0.036 0.5479 0.5479
0.028 0.2675 0.2675
0.0555 0.5487 0.5486
0.0501 0.5441 0.544
0.0962 0.2933 0.2933
0.0928 0.3155 0.3146
0.0430936 0.337807 1
0.0477 0.5545 0.5535
0.062 0.7074 0.8075
0.0298 0.2723 0.2755
0.0343 0.2521 0.2961
0.0453 0.3176 0.5497
0.0341 0.3105 1
0.0478 0.4969 0.5546
0.0356 0.539 0.5307
0.0489 0.382 0.5472
0.0749 0.3123 0.3121
0.2232 0.3652 0.365
0.1209 0.2723 0.272
0.0605 0.5815 0.5815
0.0947 0.2812 0.2807
0.0123 0.3181 0.7542
0.0414 0.3402 0.6485
0.1453 0.2717 0.3279
0.1065 0.4035 0.5546
0.1121 0.5477 0.5466
0.0533 0.4606 0.624
0.0204 0.33 1
0.048 0.2619 0.2579
0.0836 0.3378 0.3378
0.0791 0.5782 0.9171
0.0811 0.5466 0.5459
0.0054 0.2831 1
0.0144 0.3168 0.3168
0.0531 0.3174 0.5827
0.0586 0.2956 0.2956
0.0542 0.5995 0.5959
0.1771 0.2704 0.2704
0.0639 0.7102 0.8025
0.0226 0.2575 1
0.0418 0.2896 0.4738
0.0144 0.275 0.9095
0.0478 0.5477 0.5477
0.0533 0.4606 0.624
0.0789 0.2955 0.2952
0.0455 0.3483 1
0.027 0.2767 0.2767
0.0459 0.5539 0.5535
0.0915 0.2625 0.2623
0.0066 0.2823 1
0.0842 0.5495 0.9196
0.0505 0.2831 1
0.0867 0.4084 0.5595
0.0505 0.2831 1
0.0511 0.5831 0.5827
0.2037 0.2845 0.2844
0.1121 0.5466 0.5459
0.0875 0.2868 0.2865
0.1099 0.3053 0.3053
0.0166 0.3011 1
0.0505 0.2831 1
0.0752 0.3323 1
0.0401 0.2831 0.5898
0.0967 0.2813 0.2813
0.0757 0.282 0.2809
0.1073 0.4994 0.8998
0.113 0.4884 0.5715
0.0459 0.5539 0.5535
0.1732 0.2676 0.4531
0.0401 0.2831 0.5898
0.0216 0.3338 1
0.028 0.2675 0.2675
0.028 0.2675 0.2675
0.1141 0.3024 0.3014
0.0551 0.5548 0.5546
0.0605 0.5946 0.5943
0.012 0.2903 0.9902
0.0281 0.2673 0.5409
0.2232 0.3652 0.365
0.0157 0.3278 1
0.0689 0.6464 0.8702
0.0498 0.5001 0.5477
0.0526 0.5406 0.5516
0.0868 0.2713 0.2707
0.1065 0.4051 0.5558
0.0867 0.4084 0.5595
0.0946 0.2967 0.2805
0.0303 0.3395 0.5449
0.0216 0.3213 1
0.1127 0.2649 0.2649
0.0583 0.2829 0.3421
0.0789 0.3117 0.4673
0.1243 0.2529 0.2527
0.0343 0.2521 0.2961
0.0213 0.3416 1
0.0454 0.5486 0.5486
0.0551 0.5548 0.5546
0.0123 0.2769 0.6107
0.1304 0.3448 0.3844
0.2232 0.3652 0.365
0.1304 0.3448 0.3844
0.0782 0.2592 0.2676
0.0807 0.2719 0.2715
0.0181 0.3224 1
0.1003 0.4459 0.4451
0.0667 0.656 0.8617
0.0531 0.3174 0.5827
0.0248 0.3105 0.5466
0.0338 0.2831 1
0.0221 0.3426 1
0.0533 0.2928 0.2928
0.0243 0.2736 0.7535
0.0062 0.2831 1
0.1065 0.5466 0.5459
0.0521 0.2639 0.2639
0.0184 0.3402 0.4054
0.0092 0.2754 1
0.1299 0.3064 0.3038
0.095 0.5532 0.5566
0.0613 0.7313 0.783
0.0101 0.2793 0.6051
0.0505 0.2831 1
0.1341 0.2641 0.2615
0.007 0.2831 1
0.0084 0.2831 1
0.0551364 0.393741 0.553585
0.0586 0.2964 0.2949
0.4415 0.3392 0.3391
0.1046 0.4494 0.4485
0.0784 0.5829 0.6506
0.0739 0.2964 0.59
0.0847 0.5492 0.9194
0.0869 0.398 0.3971
0.1078 0.2995 0.2992
0.1566 0.2675 0.2675
0.149 0.3086 0.3819
0.0756 0.268 0.268
0.0547 0.586 0.5844
0.1191 0.3013 0.3013
0.015 0.261 0.4734
0.0752 0.3323 1
0.0435 0.352 0.9577
0.095 0.5532 0.5566
0.0667 0.542 0.5925
0.0453 0.3176 0.5497
0.028 0.2675 0.2675
0.1213 0.2628 0.2609
0.0465 0.5486 0.5486
0.0184 0.2983 0.2983
0.0166 0.3011 1
0.0667 0.542 0.5925
0.0435 0.352 0.9577
0.0243 0.2736 0.7535
0.0265 0.3085 0.9563
0.0505 0.2831 1
0.1015 0.2707 0.523
0.0155 0.3243 0.9795
0.0191 0.3208 1
0.0581 0.3377 0.5743
0.1893 0.2735 0.2735
0.083 0.2644 0.264
0.0165 0.2818 0.3789
0.005 0.2831 1
0.0915 0.2625 0.2623
0.0631 0.6735 0.6735
0.1252 0.2776 0.417
0.0566 0.2849 0.3059
0.012 0.2526 1
0.0751 0.2939 0.2939
0.0167 0.2996 1
0.101 0.4051 0.5558
0.0652 0.3159 0.7071
0.0452 0.2891 0.5307
0.0195 0.3213 1
0.1122 0.2555 0.2538
0.1565 0.3908 0.3901
0.0163 0.2999 1
0.0389 0.3414 0.5014
0.1623 0.3141 0.3497
0.1073 0.5466 0.5459
0.1129 0.5466 0.5459
0.1061 0.2831 0.2831
0.0624 0.6294 0.6282
0.0819 0.4186 0.4176
0.1134 0.2999 0.7592
0.0151 0.2831 1
0.1623 0.3141 0.3497
0.1975 0.3886 0.3896
0.0549 0.5477 0.5477
0.1042 0.2776 0.3412
0.0385 0.2609 0.2609
0.0167 0.3272 0.4612
0.0695 0.2739 0.3518
0.0213 0.3335 1
0.0041 0.3057 1
0.0631 0.6735 0.6735
0.0187 0.2859 1
0.2002 0.3122 0.4371
0.0863 0.2991 0.298
0.0947 0.2812 0.2807
0.0505 0.5413 0.5445
0.0505 0.2831 1
0.05 0.4913 0.5444
0.0509 0.5477 0.5477
0.0481 0.5535 0.5535
0.0173 0.3192 1
0.0545 0.5545 0.5535
0.0802 0.3277 0.7317
0.1173 0.2609 0.2608
0.0906 0.4051 0.5558
0.0565 0.4388 0.5844
0.0414 0.3402 0.6485
0.1565 0.3908 0.3901
0.2232 0.3652 0.365
0.0265 0.2799 1
0.0875 0.3268 0.9208
0.099 0.3625 0.4376
0.0495 0.4855 0.5443
0.159 0.4361 0.5034
0.0655 0.3075 0.5821
0.0464 0.2671 0.2671
0.0509 0.5545 0.5535
0.1015 0.2707 0.523
0.0476 0.2712 0.2712
0.0192 0.2831 1
0.0162 0.3284 1
0.0833 0.4417 0.4412
0.0454 0.549 0.5486
0.028 0.2675 0.2675
0.014 0.2866 0.4281
0.0587 0.365 0.5682
0.0867 0.3006 0.3006
0.113 0.4884 0.5715
0.0165 0.2818 0.3789
0.0889 0.3632 0.3621
0.0084 0.3153 1
0.0564 0.3372 0.6748
0.0599 0.3253 0.8541
0.0555 0.5518 0.5516
0.0106 0.2831 1
0.111 0.3492 0.3488
0.0463 0.6345 0.6334
0.0636 0.4789 0.8029
0.0122 0.3219 0.4195
0.028 0.2675 0.2675
0.0478 0.3343 0.5566
0.0087 0.3153 1
0.201 0.2815 0.2815
0.0236 0.2786 0.3544
0.0477 0.29 0.4503
0.0636 0.7096 0.8053
0.1299 0.2798 0.2789
0.1018 0.5466 0.5459
0.0414 0.3402 0.6485
0.1453 0.2717 0.3279
0.1565 0.3908 0.3901
0.012 0.3132 0.8614
0.4127 0.3125 0.3125
0.048 0.3094 0.5431
0.0612 0.4594 0.5539
0.1315 0.2521 0.2521
0.0969 0.2821 0.2821
0.0526 0.4015 0.5844
0.0476 0.5477 0.5477
0.0803 0.5764 0.7441
0.0811 0.4057 0.5568
0.1104 0.3055 0.3055
0.0418 0.2662 0.8846
0.0555 0.5518 0.5516
0.0454 0.549 0.5486
0.1549 0.2611 0.2608
0.1366 0.2589 0.2589
0.049 0.5477 0.5477
0.056 0.2513 0.5411
0.0176 0.2717 1
0.0545 0.5518 0.5516
0.0415 0.2503 0.3963
0.0338 0.2921 0.2921
0.0343 0.2521 0.2961
0.0392 0.2563 0.2618
0.0635 0.6933 0.8144
0.0477 0.263 0.5397
0.0497 0.5862 0.5861
0.0494 0.5428 0.544
0.0106 0.2831 1
0.0465 0.5486 0.5486
0.0474 0.4954 0.544
0.0493 0.5782 0.5702
0.1745 0.2696 0.2691
0.1369 0.2617 0.2615
0.0159 0.3065 1
0.159 0.4361 0.5034
0.0811 0.3981 0.5489
0.0539 0.5402 0.5391
0.083 0.3339 0.3331
0.0796 0.2841 0.2836
0.1422 0.2762 0.4391
0.0752 0.3323 1
0.007 0.2831 1
0.0891 0.2776 0.2776
0.1402 0.4316 0.4316
0.036 0.5466 0.5459
0.0502 0.2965 0.2965
0.1195 0.2792 0.2792
0.1439 0.2674 0.2673
0.1623 0.3141 0.3497
0.0458 0.5486 0.5486
0.0739 0.3759 0.3743
0.085 0.2584 0.2584
0.0958 0.3094 0.3088
0.0605 0.5946 0.5943
0.0062 0.2831 1
0.0962 0.5466 0.5459
0.0472 0.2552 0.2527
0.1121 0.5459 0.5459
0.0977 0.2961 0.2961
0.0551 0.5548 0.5546
0.0188 0.3319 1
0.1304 0.3448 0.3844
0.0752 0.3323 1
0.1565 0.3908 0.3901
0.0476 0.2831 1
0.0627 0.5147 0.819
0.0478 0.4969 0.5546
0.0473 0.2506 0.2506
0.0733 0.4776 0.5971
0.1073 0.5466 0.5459
0.0601 0.6077 0.6048
0.1207 0.2985 0.2704
0.0672 0.6525 0.8585
0.0767 0.4094 0.4087
0.0505 0.2831 1
0.0465 0.5486 0.5486
0.1018 0.5466 0.5459
0.0456 0.5539 0.5535
0.0967 0.2813 0.2813
0.0509 0.5486 0.5486
0.113 0.4884 0.5715
0.1042 0.2776 0.3412
0.1091 0.2829 0.2829
0.0069 0.2552 1
0.0549 0.5477 0.5477
0.0473 0.2506 0.2506
0.0351 0.3287 0.6123
0.0171 0.2652 1
0.0363 0.5576 0.5573
0.0229 0.2571 0.8967
0.0752 0.3323 1
0.0763 0.3018 0.3014
0.1838 0.2666 0.2666
0.0837 0.3073 0.9198
0.0324 0.3319 1
0.1097 0.2995 0.2891
0.1399 0.3196 0.331
0.0212 0.2736 0.3795
0.0484 0.5539 0.5535
0.0045 0.2831 1
0.1523 0.2681 0.267
0.0855 0.3002 0.2998
0.1623 0.3141 0.3497
0.121 0.2735 0.2733
0.0563 0.6532 0.653
0.0324 0.3319 1
0.1146 0.2695 0.2695
0.0523 0.5844 0.5844
0.059 0.2818 0.2818
0.201 0.2815 0.2815
0.1141 0.3024 0.3014
0.0796 0.2765 0.2765
0.0583 0.2829 0.3421
0.0218 0.3465 1
0.0667 0.542 0.5925
0.0499 0.5486 0.5486
0.0565 0.4388 0.5844
0.0276 0.3494 1
0.0547 0.2835 0.5827
0.0622 0.6448 0.8083
0.0168 0.3001 1
0.0624 0.6294 0.6282
0.1083 0.259 0.2878
0.3562 0.2982 0.2942
0.0689 0.6464 0.8702

Assayability

Assay information

No assay information for this target.

Reagent availability

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Gene identifier TcCLB.503909.84 (Trypanosoma cruzi), calpain-like cysteine peptidase, putative
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