Detailed view for CaO19_5169

Basic information

TDR Targets ID: 658681
Candida albicans, hypothetical protein
Source Database / ID:  KEGG  

pI: 5.9449 | Length (AA): 573 | MW (Da): 63897 | Paralog Number: 5

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF01425   Amidase

Gene Ontology

Mouse over links to read term descriptions.
GO:0004040   amidase activity  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_127783)

Species Accession Gene Product
Brugia malayi Bm1_28250   amidase
Candida albicans CaO19.6557   one of two amidase genes similar to S. pombe SPCC550.07 and to S. cerevisiae AMD2 (YDR242W)
Candida albicans CaO19.13910   one of two amidase genes similar to S. pombe SPCC550.07 and to S. cerevisiae AMD2 (YDR242W)
Candida albicans CaO19.12636   one of two amidase genes similar to S. pombe SPCC550.07 and to S. cerevisiae AMD2 (YDR242W)
Candida albicans CaO19.5169   one of two amidase genes similar to S. pombe SPCC550.07 and to S. cerevisiae AMD2 (YDR242W)
Candida albicans CaO19_5169   hypothetical protein
Candida albicans CaO19_6557   hypothetical protein
Caenorhabditis elegans CELE_B0218.2   Protein FAAH-2
Caenorhabditis elegans CELE_F58H7.2   Protein FAAH-3
Caenorhabditis elegans CELE_B0218.1   Protein FAAH-1, isoform A
Drosophila melanogaster Dmel_CG7900   CG7900 gene product from transcript CG7900-RB
Drosophila melanogaster Dmel_CG5112   CG5112 gene product from transcript CG5112-RA
Drosophila melanogaster Dmel_CG7910   CG7910 gene product from transcript CG7910-RA
Echinococcus granulosus EgrG_000674100   fatty acid amide hydrolase 1
Echinococcus granulosus EgrG_000743700   fatty acid amide hydrolase 1
Echinococcus multilocularis EmuJ_000674100   fatty acid amide hydrolase 1
Echinococcus multilocularis EmuJ_000743700   fatty acid amide hydrolase 1
Homo sapiens ENSG00000117480   fatty acid amide hydrolase
Loa Loa (eye worm) LOAG_09182   hypothetical protein
Mus musculus ENSMUSG00000034171   fatty acid amide hydrolase
Schistosoma japonicum Sjp_0049780   Fatty-acid amide hydrolase 1, putative
Schistosoma japonicum Sjp_0060310   Fatty-acid amide hydrolase 1, putative
Schistosoma japonicum Sjp_0060320   ko:K01175 fatty acid amide hydrolase [EC:3.1.-.-], putative
Schistosoma mansoni Smp_167750   fatty-acid amide hydrolase
Schistosoma mansoni Smp_004220   amidase
Schmidtea mediterranea mk4.006890.02   Fatty-acid amide hydrolase 1
Schmidtea mediterranea mk4.002051.04   Fatty-acid amide hydrolase 1
Schmidtea mediterranea mk4.000180.11   Fatty-acid amide hydrolase 1
Schmidtea mediterranea mk4.001109.00   Fatty-acid amide hydrolase 1
Schmidtea mediterranea mk4.005541.02   Fatty-acid amide hydrolase 1
Schmidtea mediterranea mk4.002975.02   Fatty-acid amide hydrolase 1
Schmidtea mediterranea mk4.002565.01  
Schmidtea mediterranea mk4.001109.06   Fatty-acid amide hydrolase 1

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Homo sapiens fatty acid amide hydrolase Compounds References
Mus musculus fatty acid amide hydrolase Compounds References
Rattus norvegicus Anandamide amidohydrolase Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

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Gene identifier CaO19_5169 (Candida albicans), hypothetical protein
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