Escherichia coli K-12 MG1655: b3994
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Entry
b3994 CDS
T00007
Symbol
thiC
Name
(RefSeq) phosphomethylpyrimidine synthase
KO
K03147
phosphomethylpyrimidine synthase [EC:
4.1.99.17
]
Organism
eco
Escherichia coli K-12 MG1655
Pathway
eco00730
Thiamine metabolism
eco01100
Metabolic pathways
eco01240
Biosynthesis of cofactors
Module
eco_M00127
Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
Brite
KEGG Orthology (KO) [BR:
eco00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00730 Thiamine metabolism
b3994 (thiC)
Enzymes [BR:
eco01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.17 phosphomethylpyrimidine synthase
b3994 (thiC)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ThiC_Rad_SAM
ThiC-associated
Motif
Other DBs
NCBI-GeneID:
948492
NCBI-ProteinID:
NP_418422
Pasteur:
thiC
RegulonDB:
ECK120001535
ECOCYC:
EG11585
ASAP:
ABE-0013057
UniProt:
P30136
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Position
complement(4194204..4196099)
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AA seq
631 aa
AA seq
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MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSK
EQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKA
RLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEV
LRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQAL
EKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMA
KWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELT
KIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAM
SKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDY
AATQTIEMGMADMSENFRARGGEIYLRKEEA
NT seq
1896 nt
NT seq
+upstream
nt +downstream
nt
atgtctgcaacaaaactgacccgccgcgaacaacgcgcccgggcccaacattttatcgac
accctggaaggcaccgcctttcccaactcaaaacgcatttatatcactggcacacacccc
ggcgtgcgcgtgccgatgcgtgagatccagcttagcccgacgctaattggcggtagcaaa
gaacagccgcagtacgaagaaaacgaagcgattccggtctacgacacctccggcccgtat
ggtgatccgcagattgccattaacgtgcagcaagggctggcaaaactacgccagccgtgg
atcgatgcgcgcggcgataccgaagaacttaccgtgcgcagttccgattacactaaagcg
cggctggcagatgatggcctcgacgaactgcgttttagcggcgtactaacaccaaaacgc
gccaaagcaggacgccgtgtcacccaactgcactacgcccgccagggcatcatcacgccg
gaaatggaattcatcgccatccgcgagaatatgggccgcgagcgcatccgtagcgaggtt
ttacgccaccagcatccgggaatgagctttggcgcacatctgccggaaaatatcactgcg
gaatttgtccgtgatgaagttgctgccggacgtgcgattatcccggccaacattaatcat
ccggaatcggagccgatgattattggtcgcaatttcctggtaaaagttaacgccaatatc
ggcaactcggcggtcacctcttccatcgaagaagaagtggaaaagctggtatggtccacg
cgctggggagcggatacggtgatggatctctccaccggtcgctatattcacgaaacccgc
gagtggattttgcgtaacagcccggtgccgatcggtacagtgccgatctaccaggcgctg
gagaaggttaacgggatcgccgaagatcttacctgggaagcgttccgcgacacgctgctg
gaacaggccgagcaaggtgtggattacttcactatccatgcgggcgtactgctgcgctat
gtgccgatgaccgcgaaacgcctgaccggtatcgtctctcgcggcggttcgattatggcg
aaatggtgcctctcccatcatcaggaaaatttcctctatcaacacttccgcgaaatttgt
gaaatctgtgccgcttatgacgtttcgctgtcgctgggcgacggtctgcgccccggttct
attcaggacgccaacgatgaagcgcagtttgccgagctgcatacgctgggcgaactgacc
aaaattgcctgggaatatgacgtgcaggtgatgattgaaggcccaggccacgtgccgatg
cagatgatccgccgcaatatgaccgaggagttagagcactgccacgaagcgccgttttac
actctggggccgctaactaccgatattgcgccgggctatgaccacttcacgtcggggatt
ggtgcggcgatgattggctggtttggctgcgcgatgctctgttacgtaacgccaaaagag
catctgggtctgcccaataaagaagatgttaagcaggggcttatcacctataagattgct
gcccacgccgctgacctggcgaaagggcatccgggcgcgcaaattcgcgataacgccatg
tcgaaagcccgcttcgaatttcgctgggaagaccagtttaatctggccctcgacccgttt
accgcccgcgcttatcacgatgaaaccctgccgcaagagtcaggtaaagtcgcccatttt
tgctccatgtgtgggccgaaattctgctcgatgaaaatcagccaggaagtgcgtgattac
gccgccacgcaaactattgaaatgggaatggcggatatgtcggagaacttccgtgccaga
ggcggagaaatctacctgcgtaaggaggaagcgtga
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