KEGG   Homo sapiens (human): 3292
Entry
3292              CDS       T01001                                 
Symbol
HSD17B1, 17-beta-HSD, 20-alpha-HSD, E2DH, EDH17B2, EDHB17, HSD17, SDR28C1
Name
(RefSeq) hydroxysteroid 17-beta dehydrogenase 1
  KO
K00044  17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00140  Steroid hormone biosynthesis
hsa01100  Metabolic pathways
hsa04913  Ovarian steroidogenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    3292 (HSD17B1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    3292 (HSD17B1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     3292 (HSD17B1)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR Epimerase GDP_Man_Dehyd DUF1776 Eno-Rase_NADH_b Plexin_cytopl
Other DBs
NCBI-GeneID: 3292
NCBI-ProteinID: NP_000404
OMIM: 109684
HGNC: 5210
Ensembl: ENSG00000108786
UniProt: P14061
Structure
Position
17:42552923..42555214
AA seq 328 aa
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV
RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG
GAGPGAEDEAGRGAVGDPELGDPPAAPQ
NT seq 987 nt   +upstreamnt  +downstreamnt
atggcccgcaccgtggtgctcatcaccggctgttcctcgggcatcggcctgcacttggcc
gtacgtctggcttcagatccatcccagagcttcaaagtgtatgccacgttgagggacctg
aaaacacagggccggctgtgggaggcggcccgggccctggcatgccctccgggatccctg
gagacgttgcagctggacgtaagggactcaaaatccgtggccgctgcccgggaacgcgtg
actgagggccgcgtggacgtgctggtgtgtaacgcaggcctgggcctgctggggccgctg
gaggcgctgggggaggacgccgtggcctctgtgctggacgtgaatgtagtagggactgtg
cggatgctgcaggccttcctgccagacatgaagaggcgcggttcgggacgcgtgttggtg
accgggagcgtgggaggattgatggggctgcctttcaatgacgtttattgcgccagcaag
ttcgcgctcgaaggcttatgcgagagtctggcggttctgctgctgccctttggggtccac
ttgagcctgatcgagtgcggcccagtgcacaccgccttcatggagaaggtgttgggcagc
ccagaggaggtgctggaccgcacggacatccacaccttccaccgcttctaccaatacctc
gcccacagcaagcaagtctttcgcgaggcggcgcagaaccctgaggaggtggcggaggtc
ttcctcaccgctttgcgcgccccgaagccgaccctgcgctacttcaccaccgagcgcttc
ctgcccctgctgcggatgcgcctggacgaccccagcggctccaactacgtcaccgccatg
caccgggaagtgttcggcgacgttccggcaaaggccgaggctggggccgaggctgggggc
ggggccgggcctggggcagaggacgaggccgggcgcggtgcggtgggggaccctgagctc
ggcgatcctccggccgccccgcagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (43)   
   RefSeq(nuc) (3)   
   GenBank (20)   
   EMBL (20)   
3D Structure (28)   
   PDB (28)   
Protein domain (8)   
   Pfam (8)   
All databases (130)   

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