Detailed view for Sjp_0100450

Basic information

TDR Targets ID: 971248
Schistosoma japonicum, hypothetical protein
Source Database / ID:  Wormbase Parasite  

pI: 4.3657 | Length (AA): 187 | MW (Da): 21438 | Paralog Number: 4

Signal peptide: N | GPI Anchor: | Predicted trans-membrane segments: 0

Druggability Group : DG

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

No Pfam domain information for this protein.

Gene Ontology

Mouse over links to read term descriptions.
No GO information for this protein.

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_131570)

Species Accession Gene Product
Brugia malayi Bm1_46290   Bromodomain containing protein
Caenorhabditis elegans CELE_ZK783.4   Protein FLT-1
Drosophila melanogaster Dmel_CG10897   toutatis
Echinococcus granulosus EgrG_000895000   bromodomain adjacent to zinc finger domain
Echinococcus multilocularis EmuJ_000895000   bromodomain adjacent to zinc finger domain
Homo sapiens ENSG00000076108   bromodomain adjacent to zinc finger domain, 2A
Homo sapiens ENSG00000226266   bromodomain adjacent to zinc finger domain, 2B
Loa Loa (eye worm) LOAG_12358   hypothetical protein
Loa Loa (eye worm) LOAG_13083   hypothetical protein
Loa Loa (eye worm) LOAG_13007   hypothetical protein
Loa Loa (eye worm) LOAG_05113   hypothetical protein
Mus musculus ENSMUSG00000026987   bromodomain adjacent to zinc finger domain, 2B
Mus musculus ENSMUSG00000040054   bromodomain adjacent to zinc finger domain, 2A
Schistosoma japonicum Sjp_0100460   Conserved hypothetical protein
Schistosoma japonicum Sjp_0030660   ko:K01549 ATP synthase [EC3.6.3.14], putative
Schistosoma japonicum Sjp_0030670   Cleft lip and palate transmembrane protein 1-like protein, putative
Schistosoma japonicum Sjp_0311230   expressed protein
Schistosoma japonicum Sjp_0100450   hypothetical protein
Schistosoma mansoni Smp_170760   bromodomain containing protein
Schmidtea mediterranea mk4.006357.00   Bromodomain adjacent to zinc finger domain protein 2B
Schmidtea mediterranea mk4.006357.01   Toutatis
Schmidtea mediterranea mk4.012321.00   Toutatis

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Homo sapiens bromodomain adjacent to zinc finger domain, 2A Compounds References
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

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Gene identifier Sjp_0100450 (Schistosoma japonicum), hypothetical protein
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