Detailed view for Tb11.01.0355

Basic information

TDR Targets ID: 10149
Trypanosoma brucei, ribosomal protein s26, putative
Source Database / ID: TriTrypDB / Tb11.01.0355  GeneDB / Tb11.01.0355

pI: 11.8897 | Length (AA): 111 | MW (Da): 12806 | Number of Paralogs: 0

EC number(s): No EC number(s) registered for this gene.

Signal peptide: N | GPI Anchor: N (Show evidence) | Predicted trans-membrane segments: 0

Pfam domains

PF01283   Ribosomal_S26e

Gene Ontology

Component: (mouse over links to read term descriptions)

GO:0005840   ribosome  
GO:0005622   intracellular  

Function: (mouse over links to read term descriptions)

GO:0003735   structural constituent of ribosome  

Process: (mouse over links to read term descriptions)

GO:0006412   translation  
Metabolic Pathways

Ribosome (KEGG)

Functional classes

GO:0005198 structural molecule activity
GO:0009987 cellular process

Structural information

Modbase 3D models: no model available for this protein in Modbase.

PDB structures: no structure available for this protein in the PDB.

Expression

No expression information available for this gene.

Antigenicity

Number of putative antigenic epitopes: 6
Cumulative epitope score: 6.8
Normalized epitope score: 6.1
Percentile: 98.0 (this protein belongs to the top 2.0% proteins in the genome of Trypanosoma brucei, based on the predicted antigenicity).

[+/–]   More information on this prediction ...

Orthologs

OrthoMCL 4 cluster: OG4_10572
Number of Paralogs: 0

Ortholog group members from selected species:
Arabidopsis thaliana NP_181583   40S ribosomal protein S26 (RPS26A) ... |   OrthoMCL
Arabidopsis thaliana NP_191193   40S ribosomal protein S26 (RPS26C) ... |   OrthoMCL
Arabidopsis thaliana NP_181591   40S ribosomal protein S26 (RPS26B) ... |   OrthoMCL
Babesia bovis XP_001611426.1   ribosomal protein S26e ... |   OrthoMCL
Brugia malayi Bm1_00185   40S ribosomal protein S26, putative... |   OrthoMCL
Brugia malayi Bm1_00195   40S ribosomal protein S26, putative... |   OrthoMCL
Caenorhabditis elegans F39B2.6   CE16012 WBGene00004495 locus:rps-26 40S ribosomal protein S2... |   OrthoMCL
Cryptosporidium muris CMU_029020   40S ribosomal protein S26, putative ... |   OrthoMCL
Cryptosporidium neoformas XP_572351   hypothetical protein CNH01770 ... |   OrthoMCL
Cryptosporidium parvum cgd1_2270   40S ribosomal protein S26 ... |   OrthoMCL
Drosophila melanogaster FBpp0080640   |   OrthoMCL
Giardia intestinalis GL50581_2766   Ribosomal protein S26 ... |   OrthoMCL
Giardia lamblia GLP15_4537   Ribosomal protein S26 ... |   OrthoMCL
Homo sapiens ENSP00000348849   |   OrthoMCL
Homo sapiens ENSP00000375558   |   OrthoMCL
Homo sapiens ENSP00000348580   |   OrthoMCL
Leishmania braziliensis LbrM30_V2.3230   |   OrthoMCL
Leishmania braziliensis LbrM28_V2.0560   |   OrthoMCL
Leishmania infantum LinJ30_V3.3240   |   OrthoMCL
Leishmania infantum LinJ28_V3.0570   |   OrthoMCL
Leishmania major LmjF30.3200   ribosomal protein s26, putative... |   OrthoMCL
Leishmania major LmjF28.0540   ribosomal protein s26, putative... |   OrthoMCL
Leishmania mexicana LmxM28.0540   |   OrthoMCL
Leishmania mexicana LmxM29.3200   |   OrthoMCL
Mus musculus ENSMUSP00000076447   |   OrthoMCL
Mus musculus ENSMUSP00000026420   |   OrthoMCL
Neospora caninum NCLIV_018290   |   OrthoMCL
Oryza sativa NP_001044658   Os01g0823300 ... |   OrthoMCL
Oryza sativa NP_001055840   Os05g0477300 ... |   OrthoMCL
Plasmodium berghei PB001102.03.0   Ribosomal protein S26e, putative ... |   OrthoMCL
Plasmodium berghei PB000999.03.0   hypothetical protein ... |   OrthoMCL
Plasmodium chabaudi PCAS_031660   40S ribosomal protein S26e, putative ... |   OrthoMCL
P. falciparum 3D7 PFB0830w   40S ribosomal protein S26e, putative... |   OrthoMCL
Plasmodium knowlesi PKH_040230   Ribosomal protein S26e, putative ... |   OrthoMCL
Plasmodium vivax PVX_002650   40S ribosomal protein S26, putative... |   OrthoMCL
Plasmodium yoelii PY04712   Ribosomal protein S26e ... |   OrthoMCL
Saccharomyces cerevisiae YGL189C   RPS26A SGDID:S000003157, Chr VII from 148594-148235, reverse... |   OrthoMCL
Saccharomyces cerevisiae YER131W   RPS26B SGDID:S000000933, Chr V from 423948-424307, Verified ... |   OrthoMCL
Schistosoma mansoni Smp_031310   40S ribosomal protein S26, putative... |   OrthoMCL
Schistosoma mansoni Smp_183650   40S ribosomal protein S26, putative... |   OrthoMCL
Trypanosoma brucei gambiense Tbg972.11.9370   |   OrthoMCL
Trypanosoma brucei Tb11.01.0355 (this record).   ribosomal protein s26, putative... |   OrthoMCL
Trypanosoma cruzi Tc00.1047053508817.60   ribosomal protein S26, putative... |   OrthoMCL
Trypanosoma cruzi Tc00.1047053503801.20   ribosomal protein S26, putative... |   OrthoMCL
Toxoplasma gondii TGME49_043570   40S ribosomal protein S26, putative... |   OrthoMCL
Trypanosoma vivax TvY486_1108970   |   OrthoMCL

Essentiality Tb11.01.0355 has essentiality data
Gene/Ortholog: cel8563 (OG4_10572); Phenotype: Embryonic Lethal/Arrest; Source study: neb
Gene/Ortholog: cel8563 (OG4_10572); Phenotype: Larval/Adult Lethal/Arrest; Source study: neb
Gene/Ortholog: cel8563 (OG4_10572); Phenotype: Sterility; Source study: neb
Gene/Ortholog: cel8563 (OG4_10572); Phenotype: Morphology Defect; Source study: neb
Gene/Ortholog: cel8563 (OG4_10572); Phenotype: Embryonic Lethal/Arrest; Source study: wormbase
Gene/Ortholog: cel8563 (OG4_10572); Phenotype: Larval/Adult Lethal/Arrest; Source study: wormbase
Gene/Ortholog: cel8563 (OG4_10572); Phenotype: Sterility; Source study: wormbase

[+/–]   Show essentiality data references.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

Associated compounds / Druggability

  • Curated from literature

    No chemical compounds is associated to this gene

  • Predicted associations

    • By orthology to known druggable targets

      • No orthologous druggable targets

    • By sequence similarity to non orthologous druggable targets

      • No additional associated druggable targets
    • Assayability

    Assay information

    No assay information for this target.

    Reagent availability

    No reagent availability information for this target.

    Bibliographic references

    No literature references are available for this gene.

    If you have references for this gene, please enter them in a user comment (below) or contact us.

    User comments

    No user comments are available for this gene.

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