Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Homo sapiens | nuclear receptor subfamily 1, group H, member 4 | Starlite/ChEMBL | No references |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | gamma-tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | zeta tubulin, putative | Curated by TDR Targets | References |
Leishmania major | epsilon tubulin, putative | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | delta tubulin, putative | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Species | Potential target | Known druggable target | Length | Alignment span | Identity |
---|---|---|---|---|---|
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin epsilon chain, putative | gamma-tubulin | 447 aa | 479 aa | 28.2 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Trypanosoma brucei | epsilon tubulin | epsilon tubulin, putative | 470 aa | 488 aa | 68.0 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Echinococcus granulosus | ecdysone induced protein 78C | nuclear receptor subfamily 1, group H, member 4 | 476 aa | 402 aa | 28.1 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0624641 | 1 | 1 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0624641 | 1 | 1 |
Trypanosoma brucei | epsilon tubulin | 0.0394751 | 0.33193 | 0.158605 |
Echinococcus multilocularis | tubulin alpha chain | 0.047082 | 0.552988 | 0.437015 |
Schistosoma mansoni | tubulin subunit beta | 0.0624641 | 1 | 1 |
Entamoeba histolytica | tubulin alpha-1 chain | 0.047082 | 0.552988 | 0.328813 |
Brugia malayi | tubulin alpha-2 chain | 0.047082 | 0.552988 | 0.328813 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.047082 | 0.552988 | 0.437015 |
Echinococcus multilocularis | tubulin subunit beta | 0.0624641 | 1 | 1 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.047082 | 0.552988 | 0.437015 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0624641 | 1 | 1 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Trypanosoma brucei | tubulin delta chain | 0.0427869 | 0.428172 | 0.279815 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0624641 | 1 | 1 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0624641 | 1 | 1 |
Loa Loa (eye worm) | tubulin beta-1 chain | 0.0624641 | 1 | 1 |
Trypanosoma cruzi | tubulin delta chain | 0.0427869 | 0.428172 | 0.144059 |
Trypanosoma brucei | zeta tubulin, putative | 0.0605303 | 0.943804 | 0.929225 |
Echinococcus multilocularis | tubulin alpha chain | 0.047082 | 0.552988 | 0.437015 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0309692 | 0.0847428 | 0.0847428 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Schistosoma mansoni | tubulin subunit alpha | 0.047082 | 0.552988 | 0.330891 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Trypanosoma cruzi | beta tubulin, putative | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0394751 | 0.33193 | 0.33193 |
Loa Loa (eye worm) | tubulin alpha chain | 0.047082 | 0.552988 | 0.552988 |
Trypanosoma brucei | beta tubulin | 0.0624641 | 1 | 1 |
Toxoplasma gondii | beta-1 tubulin, putative | 0.0624641 | 1 | 1 |
Schistosoma mansoni | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Trypanosoma brucei | beta tubulin | 0.0624641 | 1 | 1 |
Entamoeba histolytica | tubulin alpha chain, putative | 0.047082 | 0.552988 | 0.328813 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.047082 | 0.552988 | 0.437015 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Loa Loa (eye worm) | tubulin beta-4 chain | 0.0624641 | 1 | 1 |
Echinococcus multilocularis | tubulin beta 1 chain | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.047082 | 0.552988 | 0.552988 |
Loa Loa (eye worm) | tubulin alpha-2 chain | 0.047082 | 0.552988 | 0.552988 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.047082 | 0.552988 | 0.437015 |
Trypanosoma brucei | beta tubulin | 0.0624641 | 1 | 1 |
Schistosoma mansoni | tubulin subunit gamma | 0.0395463 | 0.333999 | 0.00309586 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0605303 | 0.943804 | 0.915883 |
Echinococcus granulosus | beta tubulin | 0.0624641 | 1 | 1 |
Brugia malayi | Tubulin alpha chain | 0.047082 | 0.552988 | 0.328813 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Schistosoma mansoni | tubulin subunit beta | 0.0624641 | 1 | 1 |
Loa Loa (eye worm) | alpha-tubulin | 0.047082 | 0.552988 | 0.552988 |
Echinococcus granulosus | tubulin subunit TubB | 0.047082 | 0.552988 | 0.437015 |
Loa Loa (eye worm) | tubulin alpha chain | 0.047082 | 0.552988 | 0.552988 |
Giardia lamblia | Alpha-tubulin | 0.047082 | 0.552988 | 0.328813 |
Plasmodium falciparum | tubulin gamma chain | 0.0395463 | 0.333999 | 0.00309586 |
Trypanosoma brucei | beta tubulin | 0.0624641 | 1 | 1 |
Loa Loa (eye worm) | alpha-tubulin | 0.047082 | 0.552988 | 0.552988 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0395463 | 0.333999 | 0.333999 |
Brugia malayi | alpha-tubulin | 0.047082 | 0.552988 | 0.328813 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0605303 | 0.943804 | 0.915883 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.047082 | 0.552988 | 0.437015 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Schistosoma mansoni | tubulin subunit alpha | 0.047082 | 0.552988 | 0.330891 |
Echinococcus granulosus | tubulin epsilon chain | 0.0394751 | 0.33193 | 0.158605 |
Plasmodium vivax | tubulin alpha chain, putative | 0.047082 | 0.552988 | 0.330891 |
Loa Loa (eye worm) | alpha-tubulin isotype 2 | 0.0309692 | 0.0847428 | 0.0847428 |
Echinococcus granulosus | tubulin alpha chain | 0.047082 | 0.552988 | 0.437015 |
Plasmodium falciparum | alpha tubulin 2 | 0.047082 | 0.552988 | 0.330891 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.047082 | 0.552988 | 0.437015 |
Giardia lamblia | Beta tubulin | 0.0624641 | 1 | 1 |
Echinococcus multilocularis | tubulin alpha chain | 0.047082 | 0.552988 | 0.437015 |
Schistosoma mansoni | tubulin subunit beta | 0.0624641 | 1 | 1 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0624641 | 1 | 1 |
Giardia lamblia | Alpha-tubulin | 0.047082 | 0.552988 | 0.328813 |
Schistosoma mansoni | tubulin subunit beta | 0.0624641 | 1 | 1 |
Toxoplasma gondii | beta tubulin | 0.0624641 | 1 | 1 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Plasmodium falciparum | tubulin beta chain | 0.0624641 | 1 | 1 |
Entamoeba histolytica | tubulin family protein | 0.0624641 | 1 | 1 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.047082 | 0.552988 | 0.437015 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.047082 | 0.552988 | 0.437015 |
Leishmania major | zeta tubulin, putative | 0.0605303 | 0.943804 | 0.915883 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0624641 | 1 | 1 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Echinococcus multilocularis | hypothetical protein | 0.047082 | 0.552988 | 0.437015 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.047082 | 0.552988 | 0.437015 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.047082 | 0.552988 | 0.437015 |
Echinococcus multilocularis | tubulin, beta 4A class IVa | 0.0624641 | 1 | 1 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Leishmania major | gamma-tubulin | 0.0395463 | 0.333999 | 0.00309586 |
Loa Loa (eye worm) | tubulin beta-2A chain | 0.0624641 | 1 | 1 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Trypanosoma cruzi | tubulin gamma chain | 0.0395463 | 0.333999 | 0.00309586 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Schistosoma mansoni | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Plasmodium vivax | tubulin gamma chain, putative | 0.0395463 | 0.333999 | 0.00309586 |
Echinococcus granulosus | tubulin beta 4A class IVa | 0.0624641 | 1 | 1 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0309692 | 0.0847428 | 0.0847428 |
Loa Loa (eye worm) | beta-tubulin | 0.0624641 | 1 | 1 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0427869 | 0.428172 | 0.279815 |
Loa Loa (eye worm) | tubulin gamma chain | 0.0395463 | 0.333999 | 0.333999 |
Leishmania major | delta tubulin, putative | 0.0427869 | 0.428172 | 0.144059 |
Trypanosoma brucei | tubulin gamma chain | 0.0395463 | 0.333999 | 0.16121 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.047082 | 0.552988 | 0.552988 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.047082 | 0.552988 | 0.552988 |
Toxoplasma gondii | alpha-tubulin I, putative | 0.047082 | 0.552988 | 0.437015 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Brugia malayi | tubulin alpha chain - mouse | 0.047082 | 0.552988 | 0.328813 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.047082 | 0.552988 | 0.437015 |
Toxoplasma gondii | alpha tubulin TUBA1 | 0.047082 | 0.552988 | 0.437015 |
Echinococcus granulosus | beta tubulin | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.047082 | 0.552988 | 0.552988 |
Toxoplasma gondii | beta-tubulin, putative | 0.0624641 | 1 | 1 |
Schistosoma mansoni | tubulin subunit beta | 0.0624641 | 1 | 1 |
Entamoeba histolytica | tubulin family protein | 0.0624641 | 1 | 1 |
Brugia malayi | Tubulin alpha-2 chain | 0.047082 | 0.552988 | 0.328813 |
Echinococcus granulosus | tubulin subunit beta | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0624641 | 1 | 1 |
Loa Loa (eye worm) | BEN-1 protein | 0.0624641 | 1 | 1 |
Schistosoma mansoni | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Plasmodium vivax | tubulin alpha chain, putative | 0.047082 | 0.552988 | 0.330891 |
Echinococcus granulosus | alpha tubulin | 0.047082 | 0.552988 | 0.437015 |
Schistosoma mansoni | tubulin subunit alpha | 0.047082 | 0.552988 | 0.330891 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0624641 | 1 | 1 |
Echinococcus multilocularis | tubulin alpha chain | 0.047082 | 0.552988 | 0.437015 |
Echinococcus multilocularis | tubulin alpha chain | 0.047082 | 0.552988 | 0.437015 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.047082 | 0.552988 | 0.552988 |
Trypanosoma cruzi | tubulin delta chain | 0.0427869 | 0.428172 | 0.144059 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0309692 | 0.0847428 | 0.0847428 |
Echinococcus granulosus | tubulin alpha chain | 0.047082 | 0.552988 | 0.437015 |
Loa Loa (eye worm) | BEN-1 protein | 0.0624641 | 1 | 1 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Plasmodium vivax | tubulin beta chain, putative | 0.0624641 | 1 | 1 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.047082 | 0.552988 | 0.552988 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0624641 | 1 | 1 |
Echinococcus granulosus | tubulin alpha chain | 0.047082 | 0.552988 | 0.437015 |
Schistosoma mansoni | tubulin subunit beta | 0.0624641 | 1 | 1 |
Giardia lamblia | Beta tubulin | 0.0624641 | 1 | 1 |
Loa Loa (eye worm) | tubulin beta chain | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.047082 | 0.552988 | 0.552988 |
Echinococcus granulosus | tubulin alpha chain | 0.047082 | 0.552988 | 0.437015 |
Trypanosoma brucei | zeta tubulin | 0.0605303 | 0.943804 | 0.929225 |
Brugia malayi | Tubulin alpha-2 chain | 0.047082 | 0.552988 | 0.328813 |
Plasmodium falciparum | alpha tubulin 1 | 0.047082 | 0.552988 | 0.330891 |
Echinococcus multilocularis | beta tubulin | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0624641 | 1 | 1 |
Brugia malayi | Tubulin beta-1 chain | 0.0624641 | 1 | 1 |
Trypanosoma brucei | alpha tubulin | 0.047082 | 0.552988 | 0.437015 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.047082 | 0.552988 | 0.552988 |
Loa Loa (eye worm) | hypothetical protein | 0.0309692 | 0.0847428 | 0.0847428 |
Echinococcus multilocularis | peroxisome assembly protein 26 | 0.047082 | 0.552988 | 0.437015 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Giardia lamblia | Beta tubulin | 0.0624641 | 1 | 1 |
Echinococcus granulosus | peroxisome assembly protein 26 | 0.047082 | 0.552988 | 0.437015 |
Trypanosoma brucei | alpha tubulin | 0.047082 | 0.552988 | 0.437015 |
Echinococcus multilocularis | tubulin epsilon chain | 0.0394751 | 0.33193 | 0.158605 |
Trichomonas vaginalis | tubulin, putative | 0.0624641 | 1 | 1 |
Trypanosoma cruzi | alpha tubulin, putative | 0.047082 | 0.552988 | 0.330891 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.047082 | 0.552988 | 0.552988 |
Brugia malayi | beta-tubulin, identical | 0.0624641 | 1 | 1 |
Trypanosoma brucei | alpha tubulin | 0.047082 | 0.552988 | 0.437015 |
Leishmania major | alpha tubulin | 0.047082 | 0.552988 | 0.330891 |
Trypanosoma brucei | alpha tubulin | 0.047082 | 0.552988 | 0.437015 |
Echinococcus multilocularis | beta tubulin | 0.0624641 | 1 | 1 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0624641 | 1 | 1 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0624641 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.047082 | 0.552988 | 0.552988 |
Echinococcus multilocularis | tubulin gamma 1 chain | 0.0395463 | 0.333999 | 0.16121 |
Echinococcus granulosus | tubulin alpha chain | 0.047082 | 0.552988 | 0.437015 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.047082 | 0.552988 | 0.437015 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.047082 | 0.552988 | 0.437015 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0624641 | 1 | 1 |
Echinococcus granulosus | tubulin gamma 1 chain | 0.0395463 | 0.333999 | 0.16121 |
Leishmania major | beta tubulin | 0.0624641 | 1 | 1 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.047082 | 0.552988 | 0.437015 |
Echinococcus granulosus | tubulin beta 1 chain | 0.0624641 | 1 | 1 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0351417 | 0.205997 | 0.205997 |
Echinococcus multilocularis | tubulin subunit TubB | 0.047082 | 0.552988 | 0.437015 |
Trypanosoma brucei | epsilon tubulin | 0.0394751 | 0.33193 | 0.158605 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 0.19 uM | Antimicrobial activity against Cryptosporidium parvum by short-term in vitro culture assay | ChEMBL. | 20145086 |
IC50 (functional) | = 0.26 uM | Antimicrobial activity against Toxoplasma gondii RH infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 0.34 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235V mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 0.71 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235T mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 0.75 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin S6I mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 1 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235L mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 1.1 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243C mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 2.5 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin H28Q mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 3.2 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin V4L mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 3.2 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin F24H mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 9.7 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243S mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 12.2 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin T239I mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 13.2 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin L136F mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
Potency (functional) | 0.0002 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of farnesoid X receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 24.5292 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 25.1189 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 27.306 uM | PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 39.8107 uM | PubChem BioAssay. qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 61.9396 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 62.4981 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Toxoplasma gondii | 20145086 | ||
Cryptosporidium parvum | ChEMBL23 | 20145086 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
Affected Entity | Phenotypic quality | Occurs in | Occurs at | Evidence | Observed in | Targets |
---|---|---|---|---|---|---|
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 |
3 literature references were collected for this gene.