Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.1028 | 1 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.1028 | 1 | 0.5 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.0292 | 0.0292 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.1028 | 1 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.1028 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1028 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0148 | 0.1092 | 0.0982 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0717 | 0.6851 | 0.6851 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1028 | 1 | 0.5 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.0292 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.1092 | 0.0982 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0069 | 0.0292 | 0.5 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.1028 | 1 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.1028 | 1 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0717 | 0.6851 | 0.6756 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.1028 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1028 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.1028 | 1 | 1 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.0292 | 0.0292 |
Onchocerca volvulus | 0.0148 | 0.1092 | 0.5 | |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.1028 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1028 | 1 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase | 0.1028 | 1 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.1028 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.1028 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.1028 | 1 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.1028 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1028 | 1 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0717 | 0.6851 | 0.6851 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1028 | 1 | 0.5 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0069 | 0.0292 | 0.0172 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.