Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.004 | 0.147 | 0.3932 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.2996 | 0.8012 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0048 | 0.1971 | 0.5658 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 0.3022 | 0.8083 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.3024 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0018 | 0.0083 | 0.0126 |
Echinococcus granulosus | RUN | 0.004 | 0.147 | 0.147 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0018 | 0.0083 | 0.0309 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0059 | 0.2701 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.3024 | 1 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0018 | 0.0083 | 0.13 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0018 | 0.0083 | 0.0126 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Brugia malayi | Blistered cuticle protein 3 | 0.0064 | 0.3022 | 0.8083 |
Brugia malayi | RNA binding protein | 0.0064 | 0.2996 | 0.8012 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0023 | 0.0076 |
Echinococcus multilocularis | 0.0018 | 0.0083 | 0.0083 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.3024 | 1 |
Onchocerca volvulus | 0.0064 | 0.3022 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0023 | 0.0076 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0023 | 0.0061 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.147 | 0.4203 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0027 | 0.0642 | 0.1799 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0109 | 0.5835 | 0.8837 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.3024 | 1 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0082 | 0.0171 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 0.2701 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.3466 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0808 | 0.2672 |
Loa Loa (eye worm) | glutathione reductase | 0.0048 | 0.1971 | 0.5658 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0018 | 0.0083 | 0.13 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.3024 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 0.2701 | 1 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0204 | 0.0204 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0393 | 0.0393 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0121 | 0.6603 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0121 | 0.6603 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0018 | 0.0083 | 0.0126 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0109 | 0.5835 | 0.8837 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0018 | 0.0083 | 0.13 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0018 | 0.0083 | 0.13 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0018 | 0.0083 | 0.0126 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.1398 | 0.3739 |
Brugia malayi | hypothetical protein | 0.004 | 0.147 | 0.3932 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.3024 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0064 | 0.3022 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0023 | 0.0023 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0023 | 0.0023 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0018 | 0.0083 | 0.0276 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0023 | 0.0061 |
Echinococcus multilocularis | peroxidasin | 0.0064 | 0.3022 | 0.3022 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.3024 | 1 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0018 | 0.0083 | 0.13 |
Schistosoma mansoni | bromodomain containing protein | 0.0064 | 0.2991 | 0.2991 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0059 | 0.2701 | 0.8932 |
Brugia malayi | Peroxidasin | 0.0064 | 0.3022 | 0.8083 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Brugia malayi | hypothetical protein | 0.0064 | 0.3022 | 0.8083 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0018 | 0.0083 | 0.13 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0023 | 0.0061 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0271 | 0.0721 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0109 | 0.5835 | 0.8822 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0109 | 0.5835 | 0.8837 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0023 | 0.0023 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0109 | 0.5835 | 0.8837 |
Echinococcus granulosus | peroxidasin | 0.0064 | 0.3022 | 0.3022 |
Plasmodium falciparum | thioredoxin reductase | 0.0048 | 0.1971 | 1 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0018 | 0.0083 | 0.13 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.3024 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.3024 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 0.3022 | 0.8083 |
Echinococcus granulosus | geminin | 0.0171 | 0.9764 | 0.9764 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0121 | 0.6603 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0064 | 0.3024 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0051 | 0.2153 | 0.712 |
Echinococcus multilocularis | geminin | 0.0171 | 0.9764 | 0.9764 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0018 | 0.0083 | 0.0126 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0023 | 0.0061 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.004 | 0.147 | 0.147 |
Brugia malayi | MAP kinase sur-1 | 0.0059 | 0.2701 | 0.7225 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.2763 | 0.2763 |
Onchocerca volvulus | Peroxidasin homolog | 0.0064 | 0.3022 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0017 | 0.0023 | 0.0116 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0023 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 0.2701 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0059 | 0.2701 | 0.2701 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0043 | 0.0043 |
Mycobacterium tuberculosis | Probable reductase | 0.0109 | 0.5835 | 0.8837 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Schistosoma mansoni | loxhd1 | 0.004 | 0.147 | 0.147 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0023 | 0.0023 |
Schistosoma mansoni | lipoxygenase | 0.0103 | 0.5472 | 0.5472 |
Schistosoma mansoni | cytochrome P450 | 0.0018 | 0.0083 | 0.0083 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.3024 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0018 | 0.0083 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1675 | 0.4799 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1129 | 0.1129 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 0.2701 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0048 | 0.1971 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.0023 | 0.0023 |
Schistosoma mansoni | rab6-interacting | 0.004 | 0.147 | 0.147 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0018 | 0.0083 | 0.0126 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0018 | 0.0083 | 0.0126 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 0.3022 | 0.8711 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.3024 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0271 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.147 | 0.4203 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0017 | 0 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0064 | 0.3022 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0023 | 0.5 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0018 | 0.0083 | 0.0276 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0017 | 0.0023 | 0.0116 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2996 | 0.2996 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1129 | 0.3018 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0121 | 0.6603 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0048 | 0.1971 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0023 | 0.0061 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0393 | 0.0393 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.004 | 0.147 | 0.147 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0043 | 0.0043 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Toxoplasma gondii | cathepsin CPL | 0.0017 | 0.0023 | 0.0085 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0048 | 0.1971 | 0.2985 |
Schistosoma mansoni | polycystin 1-related | 0.004 | 0.147 | 0.147 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.2135 | 0.6134 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.3024 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0023 | 0.0023 |
Plasmodium vivax | glutathione reductase, putative | 0.0048 | 0.1971 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.004 | 0.147 | 0.147 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0018 | 0.0083 | 0.0083 |
Onchocerca volvulus | Peroxidase homolog | 0.0064 | 0.3022 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0043 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0808 | 0.2281 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0023 | 0.0023 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.3024 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 0.3022 | 0.8711 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0059 | 0.2701 | 0.2701 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0059 | 0.2701 | 0.2701 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.0023 | 0.0023 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.3024 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2996 | 0.2996 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0048 | 0.1971 | 0.1971 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0018 | 0.0083 | 0.13 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0175 | 1 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0027 | 0.0642 | 0.2124 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0027 | 0.0642 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0808 | 0.41 |
Brugia malayi | Cytochrome P450 family protein | 0.0018 | 0.0083 | 0.0223 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0023 | 0.0061 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0018 | 0.0083 | 0.13 |
Leishmania major | cytochrome p450-like protein | 0.0018 | 0.0083 | 0.0276 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0017 | 0 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.1247 | 0.1247 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0018 | 0.0083 | 0.13 |
Leishmania major | cytochrome p450-like protein | 0.0027 | 0.0642 | 0.2124 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0059 | 0.2701 | 0.2701 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0064 | 0.3022 | 0.8711 |
Plasmodium falciparum | LCCL domain-containing protein | 0.004 | 0.147 | 0.7459 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1553 | 0.4445 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0023 | 0.0023 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 0.3022 | 0.8083 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0018 | 0.0083 | 0.0126 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.2135 | 0.571 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.2135 | 0.571 |
Loa Loa (eye worm) | cytochrome P450 | 0.0018 | 0.0083 | 0.0176 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0808 | 0.2992 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.004 | 0.147 | 0.147 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0023 | 0.0023 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2996 | 0.2996 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0018 | 0.0083 | 0.13 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0083 | 0.0083 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0018 | 0.0083 | 0.13 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0023 | 0.0076 |
Onchocerca volvulus | Dual oxidase homolog | 0.0064 | 0.3022 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0017 | 0.0023 | 0.0076 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0204 | 0.0204 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0059 | 0.2701 | 0.8932 |
Trypanosoma brucei | trypanothione reductase | 0.0048 | 0.1971 | 0.6518 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.2763 | 0.2763 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0018 | 0.0083 | 0.0126 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.9764 | 0.9764 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.9764 | 0.9764 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0018 | 0.0083 | 0.0126 |
Schistosoma mansoni | rab6-interacting | 0.004 | 0.147 | 0.147 |
Onchocerca volvulus | 0.0064 | 0.3022 | 1 | |
Echinococcus granulosus | Polycystic kidney disease protein | 0.004 | 0.147 | 0.147 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0048 | 0.1971 | 0.1971 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.2996 | 0.8634 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0027 | 0.0642 | 0.1799 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.1247 | 0.1247 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0018 | 0.0083 | 0.0126 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0027 | 0.0642 | 0.1799 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.3024 | 1 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0808 | 0.2161 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.2996 | 0.8012 |
Onchocerca volvulus | Peroxidase homolog | 0.0064 | 0.3022 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.3739 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 0.3022 | 0.8083 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0808 | 0.2672 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.004 | 0.147 | 0.7459 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0018 | 0.0083 | 0.0126 |
Brugia malayi | Cytochrome P450 family protein | 0.0056 | 0.2518 | 0.6734 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.2135 | 0.6134 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0018 | 0.0083 | 0.0126 |
Onchocerca volvulus | 0.004 | 0.147 | 0.4826 | |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0018 | 0.0083 | 0.0126 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.2996 | 0.8634 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Loa Loa (eye worm) | doublecortin family protein | 0.004 | 0.147 | 0.4203 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0023 | 0.0023 |
Echinococcus multilocularis | RUN | 0.004 | 0.147 | 0.147 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.2996 | 0.2996 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0023 | 0.0076 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0023 | 0.0076 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2996 | 0.2996 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0023 | 0.5 |
Treponema pallidum | NADH oxidase | 0.0017 | 0 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0064 | 0.3022 | 0.3022 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0018 | 0.0083 | 0.0276 |
Onchocerca volvulus | 0.004 | 0.147 | 0.4826 | |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0059 | 0.2701 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0018 | 0.0083 | 0.0126 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0059 | 0.2701 | 0.8932 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0059 | 0.2701 | 0.2701 |
Leishmania major | cytochrome p450-like protein | 0.0018 | 0.0083 | 0.0276 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0808 | 0.2672 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0808 | 0.41 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.2996 | 0.2996 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Brugia malayi | Doublecortin family protein | 0.004 | 0.147 | 0.3932 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.2996 | 0.8634 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0018 | 0.0083 | 0.0276 |
Brugia malayi | glutathione reductase | 0.0048 | 0.1971 | 0.5272 |
Schistosoma mansoni | lipoxygenase | 0.0175 | 1 | 1 |
Onchocerca volvulus | 0.0064 | 0.3022 | 1 | |
Brugia malayi | Cytochrome P450 family protein | 0.0027 | 0.0642 | 0.1718 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0048 | 0.1971 | 0.6518 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0018 | 0.0083 | 0.13 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0017 | 0.0043 | 0.0043 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0059 | 0.2701 | 0.8932 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.3024 | 1 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0023 | 0.0116 |
Schistosoma mansoni | peroxidasin | 0.0064 | 0.3022 | 0.3022 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0023 | 0.0116 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0017 | 0 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0059 | 0.2701 | 0.8932 |
Brugia malayi | cytochrome P450 | 0.0018 | 0.0083 | 0.0223 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0151 | 0.0405 |
Brugia malayi | Cytochrome P450 family protein | 0.0027 | 0.0642 | 0.1718 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0808 | 0.41 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0018 | 0.0083 | 0.13 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0027 | 0.0642 | 0.2124 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0059 | 0.2701 | 0.8932 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1402 | 0.4006 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0018 | 0.0083 | 0.13 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.147 | 0.147 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0018 | 0.0083 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0018 | 0.0083 | 0.0126 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0018 | 0.0083 | 0.13 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2996 | 0.2996 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1129 | 0.3211 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0023 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.0023 | 0.0076 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.004 | 0.147 | 0.147 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0018 | 0.0083 | 0.13 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0204 | 0.0204 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0059 | 0.2701 | 0.7779 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0018 | 0.0083 | 0.0276 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 0.3022 | 0.8711 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 0.3022 | 0.8711 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.3024 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0393 | 0.0393 |
Leishmania major | trypanothione reductase | 0.0048 | 0.1971 | 0.6518 |
Toxoplasma gondii | thioredoxin reductase | 0.0048 | 0.1971 | 0.7297 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0056 | 0.2518 | 0.7246 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0018 | 0.0083 | 0.13 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0018 | 0.0083 | 0.13 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0109 | 0.5835 | 0.8837 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0544 | 0.1454 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Brugia malayi | Thioredoxin reductase | 0.0048 | 0.1971 | 0.5272 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 0.3022 | 0.8083 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0018 | 0.0083 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0059 | 0.2671 | 0.8832 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0043 | 0.0043 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0018 | 0.0083 | 0.13 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0023 | 0.0085 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0027 | 0.0642 | 0.2124 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0017 | 0.0043 | 0.0043 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0017 | 0.0023 | 0.0116 |
Trypanosoma brucei | protein kinase, putative | 0.0059 | 0.2701 | 0.8932 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3022 | 0.8711 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0059 | 0.2701 | 0.8932 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0808 | 0.2672 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0018 | 0.0083 | 0.0126 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 50 uM | Inhibition of DNA polymerase beta lyase activity | ChEMBL. | 15217274 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.