Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | glutathione reductase, putative | 0.0095 | 0.2623 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.1902 | 0.1902 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0034 | 0.083 | 0.083 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0036 | 0.087 | 0.087 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0139 | 0.0152 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0034 | 0.083 | 0.083 |
Mycobacterium ulcerans | ferredoxin reductase | 0.0009 | 0.0063 | 0.0412 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0507 | 0.3799 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0009 | 0.0063 | 0.0063 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0017 | 0.0325 | 0.0325 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0139 | 0.0139 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0024 | 0.0507 | 0.1932 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0022 | 0.0464 | 0.1769 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0022 | 0.0464 | 0.7784 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.0073 | 0.0073 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.0073 | 0.0073 |
Brugia malayi | RNA binding protein | 0.007 | 0.1902 | 0.2087 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0781 | 0.2976 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh | 0.0009 | 0.0063 | 0.0412 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.0073 | 0.0073 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0507 | 0.1932 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0027 | 0.0599 | 0.0657 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0063 | 0.0063 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0034 | 0.083 | 0.1194 |
Leishmania major | hypothetical protein, conserved | 0.0009 | 0.0063 | 0.024 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0009 | 0.0063 | 0.024 |
Echinococcus multilocularis | muscleblind protein | 0.0166 | 0.4752 | 0.4752 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0139 | 0.0152 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0033 | 0.0781 | 0.5103 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0139 | 0.0139 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0033 | 0.0781 | 0.5103 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0009 | 0.0063 | 0.0063 |
Brugia malayi | TAR-binding protein | 0.007 | 0.1902 | 0.2087 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0058 | 0.153 | 1 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0032 | 0.0759 | 0.0759 |
Schistosoma mansoni | glutamate synthase | 0.0009 | 0.0063 | 0.0063 |
Giardia lamblia | DINP protein human, muc B family | 0.0025 | 0.0563 | 0.422 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0058 | 0.153 | 0.153 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.0132 | 0.0503 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0139 | 0.0139 |
Brugia malayi | hypothetical protein | 0.0312 | 0.9115 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.9115 | 0.9115 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0781 | 0.2976 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0034 | 0.083 | 0.3164 |
Plasmodium falciparum | NADPH--cytochrome P450 reductase, putative | 0.0022 | 0.0464 | 0.1769 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0139 | 0.0152 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0033 | 0.0781 | 1 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium tuberculosis | Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) | 0.0008 | 0.0041 | 0.006 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0327 | 0.1247 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0033 | 0.0781 | 0.2976 |
Mycobacterium ulcerans | hypothetical protein | 0.0009 | 0.0063 | 0.0412 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0229 | 0.0871 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0033 | 0.0781 | 0.2976 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0.0139 | 0.0152 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0139 | 0.0152 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0036 | 0.087 | 0.087 |
Echinococcus multilocularis | methionine synthase reductase | 0.0036 | 0.087 | 0.087 |
Schistosoma mansoni | ran | 0.0024 | 0.0507 | 0.0507 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0058 | 0.153 | 0.5833 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.1045 | 0.3985 |
Brugia malayi | beta-lactamase family protein | 0.0034 | 0.083 | 0.091 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0139 | 0.0139 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.005 | 0.1283 | 0.4891 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0139 | 0.0139 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0009 | 0.0063 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4752 | 0.4752 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0017 | 0.0325 | 0.0357 |
Mycobacterium tuberculosis | Conserved protein | 0.0034 | 0.083 | 0.1194 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0022 | 0.0464 | 0.7784 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0327 | 0.0327 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0139 | 0.0152 |
Mycobacterium ulcerans | DNA polymerase IV | 0.005 | 0.1283 | 0.8386 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0011 | 0.0132 | 0.0132 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0139 | 0.0139 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0027 | 0.0599 | 0.3653 |
Plasmodium falciparum | glutathione reductase | 0.0033 | 0.0781 | 0.2976 |
Echinococcus granulosus | smad | 0.0009 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | flavodoxin family protein | 0.0022 | 0.0464 | 0.0464 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0017 | 0.0325 | 0.124 |
Entamoeba histolytica | recQ family helicase, putative | 0.0014 | 0.0229 | 0.3212 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0139 | 0.0139 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0018 | 0.0327 | 0.1247 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0009 | 0.0063 | 0.024 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0139 | 0.0152 |
Brugia malayi | glutathione reductase | 0.0095 | 0.2623 | 0.2878 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0578 | 0.3512 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0073 | 0.0073 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0024 | 0.0521 | 0.0572 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.1902 | 0.1902 |
Trypanosoma brucei | NADH dehydrogenase | 0.0009 | 0.0063 | 0.024 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0139 | 0.0139 |
Echinococcus multilocularis | tar DNA binding protein | 0.007 | 0.1902 | 0.1902 |
Brugia malayi | FAD binding domain containing protein | 0.0036 | 0.087 | 0.0954 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0033 | 0.0781 | 0.2976 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0563 | 0.2146 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0009 | 0.0063 | 0.0412 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0139 | 0.0139 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Mycobacterium tuberculosis | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0009 | 0.0063 | 0.0091 |
Loa Loa (eye worm) | RNA binding protein | 0.007 | 0.1902 | 0.1902 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0139 | 0.0139 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0018 | 0.0327 | 0.0327 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Brugia malayi | isocitrate dehydrogenase | 0.0018 | 0.0327 | 0.0359 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0033 | 0.0781 | 0.2976 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0024 | 0.0507 | 0.0507 |
Plasmodium falciparum | importin beta, putative | 0.0032 | 0.0759 | 0.2893 |
Brugia malayi | Isocitrate dehydrogenase | 0.0018 | 0.0327 | 0.0359 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0009 | 0.0063 | 0.024 |
Brugia malayi | glutamate synthase | 0.0009 | 0.0063 | 0.0069 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0009 | 0.0063 | 0.024 |
Schistosoma mansoni | DNA helicase recq1 | 0.0011 | 0.0132 | 0.0132 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0032 | 0.0759 | 0.2893 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0033 | 0.0781 | 0.2976 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0033 | 0.0781 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0018 | 0.0327 | 0.0327 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0139 | 0.0139 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0073 | 0.008 |
Entamoeba histolytica | Ran family GTPase | 0.0024 | 0.0507 | 0.8611 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0011 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0009 | 0.0063 | 0.0063 |
Treponema pallidum | oxidoreductase | 0.0009 | 0.0063 | 0.0808 |
Schistosoma mansoni | glutamate synthase | 0.0009 | 0.0063 | 0.0063 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0063 | 0.0063 |
Schistosoma mansoni | glutamate synthase | 0.0009 | 0.0063 | 0.0063 |
Toxoplasma gondii | thioredoxin reductase | 0.0095 | 0.2623 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0025 | 0.0563 | 0.2146 |
Echinococcus granulosus | glutamate synthase | 0.0009 | 0.0063 | 0.0063 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0095 | 0.2623 | 1 |
Echinococcus multilocularis | smad | 0.0009 | 0.0073 | 0.0073 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0139 | 0.0139 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0058 | 0.153 | 0.153 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0216 | 0.6235 | 0.8968 |
Giardia lamblia | Thioredoxin reductase | 0.0009 | 0.0063 | 0.0473 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.0009 | 0.0063 | 0.024 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0216 | 0.6235 | 0.8958 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0327 | 0.1247 |
Mycobacterium tuberculosis | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | 0.0009 | 0.0063 | 0.0091 |
Mycobacterium tuberculosis | Probable reductase | 0.0216 | 0.6235 | 0.8968 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0058 | 0.153 | 0.5833 |
Mycobacterium tuberculosis | Conserved protein | 0.0034 | 0.083 | 0.1194 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0009 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0095 | 0.2623 | 0.2623 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0009 | 0.0063 | 0.0063 |
Echinococcus granulosus | methionine synthase reductase | 0.0036 | 0.087 | 0.087 |
Loa Loa (eye worm) | TAR-binding protein | 0.007 | 0.1902 | 0.1902 |
Onchocerca volvulus | 0.0312 | 0.9115 | 1 | |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0011 | 0.0132 | 0.099 |
Echinococcus multilocularis | dna polymerase eta | 0.0017 | 0.0325 | 0.0325 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0139 | 0.0139 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0216 | 0.6235 | 0.8968 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0507 | 0.0556 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0759 | 0.0759 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0781 | 0.2976 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0095 | 0.2623 | 1 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0009 | 0.0063 | 0.0412 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.0009 | 0.0063 | 0.024 |
Trypanosoma cruzi | p450 reductase, putative | 0.0058 | 0.153 | 0.5833 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0578 | 0.3512 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0033 | 0.0781 | 0.2976 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0017 | 0.0325 | 0.0325 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0058 | 0.153 | 0.5833 |
Leishmania major | p450 reductase, putative | 0.0058 | 0.153 | 0.5833 |
Mycobacterium ulcerans | NADPH dependent 2,4-dienoyl-CoA reductase FadH | 0.0009 | 0.0063 | 0.0412 |
Brugia malayi | RNA, U transporter 1 | 0.0091 | 0.252 | 0.2764 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0025 | 0.0563 | 0.0809 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.3806 | 0.3806 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0139 | 0.0139 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0023 | 0.0502 | 0.1915 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0139 | 0.0152 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0024 | 0.0507 | 0.1932 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0.0139 | 0.0152 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0024 | 0.0507 | 0.0507 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0009 | 0.0063 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0139 | 0.0139 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh1 | 0.0009 | 0.0063 | 0.0412 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0139 | 0.0152 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0139 | 0.0139 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0139 | 0.0139 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0034 | 0.083 | 0.5423 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.005 | 0.1283 | 0.4891 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0058 | 0.153 | 0.5833 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0009 | 0.0063 | 0.0063 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Schistosoma mansoni | DNA helicase recq5 | 0.0011 | 0.0132 | 0.0132 |
Mycobacterium tuberculosis | Possible dehydrogenase/reductase | 0.0009 | 0.0063 | 0.0091 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0033 | 0.0781 | 0.0856 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0034 | 0.083 | 0.1194 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0034 | 0.083 | 0.5227 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0139 | 0.0152 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0011 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.153 | 0.153 |
Schistosoma mansoni | NADPH flavin oxidoreductase | 0.0029 | 0.0673 | 0.0673 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0139 | 0.0152 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0139 | 0.0139 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0139 | 0.0152 |
Entamoeba histolytica | hypothetical protein | 0.0026 | 0.0578 | 1 |
Trypanosoma brucei | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0022 | 0.0464 | 0.1769 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0009 | 0.0063 | 0.024 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0009 | 0.0063 | 0.024 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0073 | 0.0073 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0325 | 0.0325 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0139 | 0.0152 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0034 | 0.083 | 0.083 |
Mycobacterium tuberculosis | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) | 0.0009 | 0.0063 | 0.0091 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0009 | 0.0063 | 0.024 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0009 | 0.0063 | 0.024 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.0132 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0139 | 0.0139 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0401 | 0.1529 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0058 | 0.153 | 0.5833 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0058 | 0.153 | 0.5833 |
Trypanosoma brucei | unspecified product | 0.0012 | 0.0163 | 0.0623 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0139 | 0.0152 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0034 | 0.083 | 0.5227 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0034 | 0.083 | 0.1194 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0033 | 0.0781 | 0.2976 |
Mycobacterium ulcerans | glutamate synthase subunit beta | 0.0009 | 0.0063 | 0.0412 |
Brugia malayi | MH2 domain containing protein | 0.0133 | 0.3758 | 0.4123 |
Mycobacterium leprae | conserved hypothetical protein | 0.0034 | 0.083 | 0.1113 |
Leishmania major | DNA polymerase eta, putative | 0.0017 | 0.0325 | 0.124 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.0073 | 0.0073 |
Chlamydia trachomatis | thioredoxin reductase | 0.0009 | 0.0063 | 0.0725 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0009 | 0.0063 | 0.024 |
Trichomonas vaginalis | esterase, putative | 0.0034 | 0.083 | 0.5227 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0507 | 0.1932 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0139 | 0.0139 |
Leishmania major | hypothetical protein, conserved | 0.0009 | 0.0063 | 0.024 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0073 | 0.0073 |
Plasmodium falciparum | glutathione reductase | 0.0095 | 0.2623 | 1 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0021 | 0.0432 | 0.0432 |
Trypanosoma brucei | unspecified product | 0.0012 | 0.0163 | 0.0623 |
Schistosoma mansoni | ran | 0.0024 | 0.0507 | 0.0507 |
Echinococcus multilocularis | glutamate synthase | 0.0009 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0139 | 0.0139 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0139 | 0.0152 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0022 | 0.0464 | 0.7784 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.1902 | 0.1902 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0009 | 0.0063 | 0.024 |
Mycobacterium ulcerans | hypothetical protein | 0.0034 | 0.083 | 0.5423 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.024 | 0.6952 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.083 | 0.083 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0009 | 0.0063 | 0.0063 |
Plasmodium falciparum | thioredoxin reductase | 0.0095 | 0.2623 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.0073 | 0.0073 |
Trypanosoma cruzi | NADPH--cytochrome P450 reductase, putative | 0.0022 | 0.0464 | 0.1769 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0033 | 0.0781 | 0.1123 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.005 | 0.1283 | 0.8316 |
Trypanosoma brucei | unspecified product | 0.0042 | 0.1045 | 0.3985 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0018 | 0.0327 | 0.047 |
Echinococcus multilocularis | dna polymerase kappa | 0.005 | 0.1283 | 0.1283 |
Giardia lamblia | Glycerol-3-phosphate dehydrogenase | 0.0009 | 0.0063 | 0.0473 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0034 | 0.083 | 0.5227 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0009 | 0.0063 | 0.024 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0216 | 0.6235 | 0.8968 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.083 | 0.083 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0139 | 0.0139 |
Leishmania major | hypothetical protein, conserved | 0.0022 | 0.0464 | 0.1769 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0139 | 0.0139 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0034 | 0.083 | 0.1194 |
Echinococcus multilocularis | bloom syndrome protein | 0.0027 | 0.0599 | 0.0599 |
Echinococcus granulosus | tar DNA binding protein | 0.007 | 0.1902 | 0.1902 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0034 | 0.083 | 0.5227 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0009 | 0.0063 | 0.0069 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.1902 | 0.1902 |
Brugia malayi | Thioredoxin reductase | 0.0095 | 0.2623 | 0.2878 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0022 | 0.0464 | 0.2734 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0139 | 0.0139 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0139 | 0.0139 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0034 | 0.083 | 0.083 |
Echinococcus granulosus | bloom syndrome protein | 0.0027 | 0.0599 | 0.0599 |
Mycobacterium tuberculosis | Conserved protein | 0.0034 | 0.083 | 0.1194 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0034 | 0.083 | 0.5423 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.0009 | 0.0063 | 0.024 |
Trichomonas vaginalis | importin beta-1, putative | 0.0026 | 0.0578 | 0.3512 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0073 | 0.008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0034 | 0.083 | 0.3164 |
Brugia malayi | flavodoxin family protein | 0.0058 | 0.153 | 0.1679 |
Echinococcus multilocularis | geminin | 0.0188 | 0.5417 | 0.5417 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0033 | 0.0781 | 0.2976 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0058 | 0.153 | 0.153 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0017 | 0.0325 | 0.124 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0024 | 0.0521 | 0.0572 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0139 | 0.0139 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0022 | 0.0464 | 0.1769 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0.0327 | 0.1247 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0034 | 0.083 | 0.5227 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0033 | 0.0781 | 0.4892 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0009 | 0.0063 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | RecQ helicase | 0.0027 | 0.0599 | 0.0599 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0073 | 0.008 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0009 | 0.0063 | 0.0063 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0139 | 0.0139 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0139 | 0.0139 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0139 | 0.0139 |
Plasmodium vivax | hypothetical protein, conserved | 0.0022 | 0.0464 | 0.1769 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0139 | 0.0139 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0009 | 0.0063 | 0.024 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0139 | 0.0139 |
Toxoplasma gondii | selenide, water dikinase | 0.0009 | 0.0063 | 0.024 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0009 | 0.0063 | 0.0069 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0033 | 0.0781 | 0.2976 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0033 | 0.0781 | 0.2976 |
Schistosoma mansoni | importin beta-1 | 0.0032 | 0.0759 | 0.0759 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0229 | 0.0871 |
Brugia malayi | beta-lactamase family protein | 0.0034 | 0.083 | 0.091 |
Treponema pallidum | flavodoxin | 0.0022 | 0.0464 | 0.5944 |
Plasmodium falciparum | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0022 | 0.0464 | 0.1769 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.083 | 0.083 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.5417 | 0.5417 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0022 | 0.0464 | 0.2734 |
Loa Loa (eye worm) | glutathione reductase | 0.0095 | 0.2623 | 0.2623 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0018 | 0.0327 | 0.0327 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0032 | 0.0759 | 0.2893 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.1902 | 0.1902 |
Echinococcus granulosus | dna polymerase kappa | 0.005 | 0.1283 | 0.1283 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.0073 | 0.0073 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0781 | 0.2976 |
Treponema pallidum | thioredoxin reductase (trxB) | 0.0009 | 0.0063 | 0.0808 |
Treponema pallidum | NADH oxidase | 0.0033 | 0.0781 | 1 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0009 | 0.0063 | 0.0063 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0166 | 0.4752 | 0.4752 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0034 | 0.083 | 0.1194 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0327 | 0.0327 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0139 | 0.0139 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0139 | 0.0152 |
Brugia malayi | Importin beta-1 subunit | 0.0032 | 0.0759 | 0.0833 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0034 | 0.083 | 0.1194 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0029 | 0.066 | 0.2517 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0139 | 0.0139 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.083 | 0.3164 |
Plasmodium vivax | hypothetical protein, conserved | 0.0034 | 0.083 | 0.3164 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0051 | 0.1334 | 0.5085 |
Mycobacterium ulcerans | lipase LipD | 0.0034 | 0.083 | 0.5423 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0401 | 0.1529 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0033 | 0.0781 | 0.2976 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0073 | 0.008 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0781 | 0.2976 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0011 | 0.0132 | 0.0503 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0216 | 0.6235 | 0.8968 |
Echinococcus granulosus | muscleblind protein | 0.0166 | 0.4752 | 0.4752 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0781 | 0.2976 |
Leishmania major | importin beta-1 subunit, putative | 0.0026 | 0.0578 | 0.2204 |
Brugia malayi | RNA recognition motif domain containing protein | 0.007 | 0.1902 | 0.2087 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0011 | 0.0132 | 0.0132 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.007 | 0.1902 | 0.1902 |
Leishmania major | NADH dehydrogenase, putative | 0.0009 | 0.0063 | 0.024 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0018 | 0.0327 | 0.1247 |
Echinococcus granulosus | dna polymerase eta | 0.0017 | 0.0325 | 0.0325 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0133 | 0.3758 | 0.3758 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0923 | 0.0923 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.005 | 0.1283 | 0.8316 |
Mycobacterium tuberculosis | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) | 0.0009 | 0.0063 | 0.0091 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.083 | 0.083 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0923 | 0.3521 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0033 | 0.0781 | 0.2976 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0033 | 0.0781 | 0.8977 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0029 | 0.066 | 0.2517 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0017 | 0.0325 | 0.0325 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0923 | 0.3521 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprB | 0.0009 | 0.0063 | 0.0412 |
Schistosoma mansoni | smad | 0.0009 | 0.0073 | 0.0073 |
Plasmodium falciparum | thioredoxin reductase | 0.0033 | 0.0781 | 0.2976 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0139 | 0.0152 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Echinococcus granulosus | importin subunit beta 1 | 0.0032 | 0.0759 | 0.0759 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0034 | 0.083 | 0.1194 |
Toxoplasma gondii | ABC1 family protein | 0.0034 | 0.083 | 0.3164 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0034 | 0.083 | 0.083 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0009 | 0.0063 | 0.024 |
Echinococcus multilocularis | snurportin 1 | 0.0342 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0781 | 0.2976 |
Mycobacterium ulcerans | beta-lactamase | 0.0034 | 0.083 | 0.5423 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0073 | 0.0073 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0058 | 0.153 | 0.5833 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0009 | 0.0063 | 0.0063 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0033 | 0.0781 | 0.0781 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0058 | 0.153 | 0.153 |
Schistosoma mansoni | sulfide quinone reductase | 0.0009 | 0.0063 | 0.0063 |
Leishmania major | DNA polymerase kappa, putative | 0.0025 | 0.0563 | 0.2146 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0009 | 0.0063 | 0.0063 |
Trichomonas vaginalis | NADPH fad oxidoreductase, putative | 0.0051 | 0.1334 | 0.8662 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0.0139 | 0.0152 |
Schistosoma mansoni | hypothetical protein | 0.0342 | 1 | 1 |
Mycobacterium ulcerans | monoxygenase | 0.0009 | 0.0063 | 0.0412 |
Giardia lamblia | Hypothetical protein | 0.0051 | 0.1334 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.4752 | 0.4752 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.024 | 0.6952 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0401 | 0.1529 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0139 | 0.0139 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0027 | 0.0599 | 0.3653 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0009 | 0.0063 | 0.0063 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0013 | 0.0203 | 0.0775 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0139 | 0.0139 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0139 | 0.0139 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.0073 | 0.0073 |
Plasmodium vivax | importin-beta 2, putative | 0.0032 | 0.0759 | 0.2893 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0018 | 0.0327 | 0.1247 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0017 | 0.0325 | 0.5087 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0139 | 0.0152 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0009 | 0.0063 | 0.024 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0009 | 0.0063 | 0.024 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0034 | 0.083 | 0.3164 |
Brugia malayi | beta-lactamase | 0.0034 | 0.083 | 0.091 |
Schistosoma mansoni | sulfide quinone reductase | 0.0009 | 0.0063 | 0.0063 |
Trypanosoma brucei | trypanothione reductase | 0.0095 | 0.2623 | 1 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.0073 | 0.0073 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0229 | 0.0871 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0.0327 | 0.1247 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0327 | 0.0327 |
Brugia malayi | FAD binding domain containing protein | 0.0058 | 0.153 | 0.1679 |
Brugia malayi | polk-prov protein | 0.0038 | 0.0923 | 0.1013 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0009 | 0.0063 | 0.0069 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0033 | 0.0781 | 0.0781 |
Onchocerca volvulus | 0.0034 | 0.083 | 0.091 | |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0018 | 0.0327 | 0.1247 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.022 | 0.6359 | 0.9147 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0009 | 0.0063 | 0.024 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.0132 | 0.0145 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0058 | 0.153 | 0.153 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0058 | 0.153 | 0.5833 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0009 | 0.0063 | 0.024 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0139 | 0.0139 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0033 | 0.0781 | 0.2976 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0033 | 0.0781 | 0.2976 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.024 | 0.6952 | 1 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0507 | 0.1932 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.024 | 0.6952 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0139 | 0.0152 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0033 | 0.0781 | 0.2976 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.5417 | 0.5417 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0026 | 0.0578 | 0.2204 |
Loa Loa (eye worm) | beta-lactamase | 0.0034 | 0.083 | 0.083 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0507 | 0.0507 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0058 | 0.153 | 0.5833 |
Mycobacterium ulcerans | thioredoxin reductase TrxB2 | 0.0009 | 0.0063 | 0.0412 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0139 | 0.0139 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0009 | 0.0063 | 0.024 |
Brugia malayi | Muscleblind-like protein | 0.0166 | 0.4752 | 0.5213 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0133 | 0.3758 | 0.3758 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0073 | 0.0073 |
Giardia lamblia | Glutamate synthase | 0.0009 | 0.0063 | 0.0473 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0139 | 0.0139 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0017 | 0.0325 | 0.0357 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0022 | 0.0464 | 0.2734 |
Leishmania major | trypanothione reductase | 0.0095 | 0.2623 | 1 |
Echinococcus granulosus | geminin | 0.0188 | 0.5417 | 0.5417 |
Trichomonas vaginalis | ran, putative | 0.0024 | 0.0507 | 0.3024 |
Onchocerca volvulus | 0.0011 | 0.0139 | 0.0152 | |
Mycobacterium ulcerans | NADH dehydrogenase | 0.0009 | 0.0063 | 0.0412 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0095 | 0.2623 | 0.3773 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0139 | 0.0152 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0018 | 0.0341 | 0.1302 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0058 | 0.153 | 0.153 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0058 | 0.153 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0033 | 0.0781 | 0.4892 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0095 | 0.264 | 0.264 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0032 | 0.0759 | 0.2893 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0033 | 0.0781 | 0.5853 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0342 | 1 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0033 | 0.0781 | 0.5103 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0033 | 0.0781 | 0.0781 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0017 | 0.0325 | 0.0325 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0139 | 0.0139 |
Mycobacterium tuberculosis | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 0.0009 | 0.0063 | 0.0091 |
Leishmania major | hypothetical protein, conserved | 0.0009 | 0.0063 | 0.024 |
Onchocerca volvulus | 0.0009 | 0.0063 | 0.0069 | |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0017 | 0.0325 | 0.0325 |
Schistosoma mansoni | DNA polymerase eta | 0.0017 | 0.0325 | 0.0325 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0018 | 0.0327 | 0.0327 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0139 | 0.0139 |
Onchocerca volvulus | 0.0034 | 0.083 | 0.091 | |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0017 | 0.0325 | 0.0468 |
Chlamydia trachomatis | sulfite reductase | 0.0036 | 0.087 | 1 |
Mycobacterium ulcerans | dehydrogenase | 0.0009 | 0.0063 | 0.0412 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.0009 | 0.0063 | 0.024 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0095 | 0.264 | 0.264 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0014 | 0.0229 | 0.1128 |
Leishmania major | GTP-binding protein, putative | 0.0024 | 0.0507 | 0.1932 |
Mycobacterium leprae | Probable lipase LipE | 0.0034 | 0.083 | 0.1113 |
Schistosoma mansoni | diflavin oxidoreductase | 0.0029 | 0.066 | 0.066 |
Leishmania major | cytochrome P450 reductase, putative | 0.0051 | 0.1334 | 0.5085 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0009 | 0.0063 | 0.0063 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0009 | 0.0063 | 0.0063 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0009 | 0.0063 | 0.024 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0034 | 0.083 | 0.091 |
Onchocerca volvulus | 0.0034 | 0.083 | 0.091 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.1283 | 0.4891 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.083 | 0.083 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0022 | 0.0464 | 0.7784 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.083 | 0.083 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0033 | 0.0781 | 0.2976 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0327 | 0.0327 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0139 | 0.0152 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0018 | 0.0335 | 0.1277 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0022 | 0.0464 | 0.7784 |
Giardia lamblia | Nitric oxide synthase, inducible | 0.0051 | 0.1334 | 1 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0009 | 0.0063 | 0.0063 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0139 | 0.0139 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0327 | 0.1247 |
Mycobacterium ulcerans | DNA polymerase IV | 0.005 | 0.1283 | 0.8386 |
Brugia malayi | flavodoxin family protein | 0.0022 | 0.0464 | 0.0509 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.0132 | 0.0503 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0058 | 0.153 | 0.5833 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0009 | 0.0063 | 0.024 |
Brugia malayi | Smad1 | 0.0009 | 0.0073 | 0.008 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0022 | 0.0464 | 0.2734 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0216 | 0.6235 | 0.8968 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.0507 | 0.1932 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 0.1 % | Inhibition of horse BChE at 2 mg/ml by Ellman's method | ChEMBL. | 23062825 |
Inhibition (binding) | = 4.86 % | Inhibition of electric eel AChE at 2 mg/ml by Ellman's method | ChEMBL. | 23062825 |
MIC90 (functional) | = 0.3 mg ml-1 | Minimum inhibitory concentration of the compound against Escherichia coli (CECT405) | ChEMBL. | 10987443 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.