Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.1185 | 0.4082 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Giardia lamblia | Beta tubulin | 0.0033 | 0.1158 | 0.2316 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0027 | 0.071 | 0.0692 |
Loa Loa (eye worm) | tubulin gamma chain | 0.0019 | 0.0172 | 0.0563 |
Trypanosoma brucei | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Loa Loa (eye worm) | tubulin beta-2A chain | 0.0033 | 0.1158 | 0.3793 |
Brugia malayi | Tubulin alpha-2 chain | 0.0027 | 0.071 | 0.2279 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0057 | 0.2766 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.145 | 0.1434 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Echinococcus granulosus | tubulin gamma 1 chain | 0.0019 | 0.0172 | 0.0153 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0019 | 0.0172 | 0.0388 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0027 | 0.071 | 0.0692 |
Toxoplasma gondii | beta-1 tubulin, putative | 0.0033 | 0.1158 | 0.4145 |
Echinococcus multilocularis | tubulin alpha chain | 0.0027 | 0.071 | 0.0692 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.0583 | 0.3221 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0027 | 0.071 | 0.0692 |
Entamoeba histolytica | modulator of drug activity B homolog, putative | 0.0021 | 0.0294 | 0.0955 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0027 | 0.071 | 0.0692 |
Echinococcus granulosus | tubulin alpha chain | 0.0027 | 0.071 | 0.0692 |
Loa Loa (eye worm) | alpha-tubulin isotype 2 | 0.0019 | 0.0165 | 0.0541 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Echinococcus granulosus | beta tubulin | 0.0033 | 0.1158 | 0.1141 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0019 | 0.0172 | 0.0555 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.145 | 0.1434 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0027 | 0.071 | 0.1604 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0057 | 0.2766 | 1 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0162 | 0.1255 |
Brugia malayi | tubulin alpha-2 chain | 0.0027 | 0.071 | 0.2279 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0027 | 0.071 | 0.0692 |
Echinococcus multilocularis | hypothetical protein | 0.0027 | 0.071 | 0.0692 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0057 | 0.2766 | 1 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0021 | 0.0294 | 0.0663 |
Brugia malayi | alpha-tubulin | 0.0027 | 0.071 | 0.2279 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0019 | 0.0172 | 0.0388 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0057 | 0.2766 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0583 | 0.1912 |
Entamoeba histolytica | tubulin alpha chain, putative | 0.0027 | 0.071 | 0.4212 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0033 | 0.1158 | 0.1141 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.0019 | 0.0172 | 0.0555 |
Trypanosoma brucei | epsilon tubulin | 0.0019 | 0.0172 | 0.0555 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0062 | 0.3052 | 0.3039 |
Plasmodium falciparum | alpha tubulin 2 | 0.0027 | 0.071 | 0.6071 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Leishmania major | epsilon tubulin, putative | 0.0019 | 0.0172 | 0.0555 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0057 | 0.2766 | 1 |
Schistosoma mansoni | tubulin subunit beta | 0.0033 | 0.1158 | 0.1141 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0057 | 0.2766 | 1 |
Schistosoma mansoni | tubulin subunit beta | 0.0033 | 0.1158 | 0.1141 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0057 | 0.2766 | 1 |
Schistosoma mansoni | tubulin subunit beta | 0.0033 | 0.1158 | 0.1141 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0057 | 0.2766 | 1 |
Brugia malayi | Tubulin gamma chain | 0.0019 | 0.0172 | 0.0503 |
Toxoplasma gondii | alpha-tubulin I, putative | 0.0027 | 0.071 | 0.2516 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Trypanosoma brucei | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Schistosoma mansoni | alpha tubulin | 0.0027 | 0.071 | 0.0692 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0033 | 0.1158 | 0.1141 |
Loa Loa (eye worm) | beta-tubulin | 0.0033 | 0.1158 | 0.3793 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0057 | 0.2766 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0294 | 0.0663 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0057 | 0.2766 | 1 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0033 | 0.1158 | 0.1141 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0027 | 0.071 | 0.1604 |
Brugia malayi | Cytochrome P450 family protein | 0.0057 | 0.2766 | 0.9056 |
Plasmodium vivax | tubulin alpha chain, putative | 0.0027 | 0.071 | 0.6071 |
Plasmodium falciparum | tubulin gamma chain | 0.0019 | 0.0172 | 0.134 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0057 | 0.2766 | 1 |
Trypanosoma cruzi | alpha tubulin, putative | 0.0027 | 0.071 | 0.2516 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0027 | 0.071 | 0.1604 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0062 | 0.3052 | 0.3039 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0057 | 0.2766 | 1 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0019 | 0.0063 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0033 | 0.1158 | 0.2614 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.145 | 0.521 |
Plasmodium falciparum | alpha tubulin 1 | 0.0027 | 0.071 | 0.6071 |
Loa Loa (eye worm) | BEN-1 protein | 0.0033 | 0.1158 | 0.3793 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.0027 | 0.071 | 0.0692 |
Echinococcus granulosus | tubulin beta 4A class IVa | 0.0033 | 0.1158 | 0.1141 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0057 | 0.2766 | 1 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Brugia malayi | cytochrome P450 | 0.0057 | 0.2766 | 0.9056 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0033 | 0.1158 | 0.2614 |
Loa Loa (eye worm) | tubulin beta-1 chain | 0.0033 | 0.1158 | 0.3793 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0057 | 0.2766 | 0.9062 |
Trypanosoma cruzi | beta tubulin, putative | 0.0033 | 0.1158 | 0.4145 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0057 | 0.2766 | 0.9062 |
Toxoplasma gondii | beta-tubulin, putative | 0.0033 | 0.1158 | 0.4145 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0057 | 0.2766 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0019 | 0.0063 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.0027 | 0.071 | 0.0692 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.145 | 0.4752 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0057 | 0.2766 | 1 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0027 | 0.071 | 0.0692 |
Toxoplasma gondii | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0038 | 0.145 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0027 | 0.071 | 0.1604 |
Echinococcus granulosus | tubulin beta 1 chain | 0.0033 | 0.1158 | 0.1141 |
Trypanosoma brucei | tubulin gamma chain | 0.0019 | 0.0172 | 0.0555 |
Echinococcus multilocularis | peroxisome assembly protein 26 | 0.0027 | 0.071 | 0.0692 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.145 | 0.3274 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Loa Loa (eye worm) | tubulin alpha-2 chain | 0.0027 | 0.071 | 0.2327 |
Echinococcus multilocularis | beta tubulin | 0.0033 | 0.1158 | 0.1141 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0583 | 0.1619 |
Brugia malayi | beta-tubulin, identical | 0.0033 | 0.1158 | 0.3754 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.0583 | 0.3221 |
Brugia malayi | Cytochrome P450 family protein | 0.0057 | 0.2766 | 0.9056 |
Plasmodium vivax | tubulin epsilon chain, putative | 0.0019 | 0.0172 | 0.134 |
Trypanosoma brucei | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0027 | 0.071 | 0.1604 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0057 | 0.2766 | 0.2752 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0294 | 0.0663 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0583 | 0.1912 |
Echinococcus multilocularis | tubulin alpha chain | 0.0027 | 0.071 | 0.0692 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0583 | 0.1861 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0062 | 0.3052 | 0.3039 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0057 | 0.2766 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.145 | 0.1434 |
Trichomonas vaginalis | tubulin, putative | 0.0033 | 0.1158 | 0.2614 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.145 | 0.3274 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0033 | 0.1158 | 0.1141 |
Echinococcus multilocularis | tubulin subunit beta | 0.0033 | 0.1158 | 0.1141 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0057 | 0.2766 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0019 | 0.0063 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0057 | 0.2766 | 1 |
Echinococcus multilocularis | tubulin, beta 4A class IVa | 0.0033 | 0.1158 | 0.1141 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0019 | 0.0063 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0027 | 0.071 | 0.0692 |
Echinococcus granulosus | tubulin alpha chain | 0.0027 | 0.071 | 0.0692 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.0583 | 0.1619 |
Echinococcus granulosus | tubulin alpha | 0.0019 | 0.0172 | 0.0153 |
Schistosoma mansoni | alpha tubulin | 0.0027 | 0.071 | 0.0692 |
Trypanosoma brucei | cytochrome P450, putative | 0.0057 | 0.2766 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0062 | 0.3052 | 0.3039 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0027 | 0.071 | 0.1604 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0057 | 0.2766 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0162 | 0.0531 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0294 | 0.0663 |
Schistosoma mansoni | cytochrome P450 | 0.0057 | 0.2766 | 0.2752 |
Entamoeba histolytica | tubulin family protein | 0.0033 | 0.1158 | 0.7711 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0019 | 0.0165 | 0.0541 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.0583 | 0.1832 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0062 | 0.3052 | 0.3039 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0165 | 0.0541 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0027 | 0.071 | 0.1604 |
Echinococcus multilocularis | tubulin gamma 1 chain | 0.0019 | 0.0172 | 0.0153 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0057 | 0.2766 | 1 |
Entamoeba histolytica | tubulin family protein | 0.0033 | 0.1158 | 0.7711 |
Schistosoma mansoni | tubulin subunit alpha | 0.0027 | 0.071 | 0.0692 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0027 | 0.071 | 0.1604 |
Schistosoma mansoni | tubulin subunit gamma | 0.0019 | 0.0172 | 0.0153 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0057 | 0.2766 | 1 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0057 | 0.2766 | 1 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0057 | 0.2766 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.145 | 0.521 |
Plasmodium vivax | tubulin beta chain, putative | 0.0033 | 0.1158 | 1 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Plasmodium vivax | tubulin alpha chain, putative | 0.0027 | 0.071 | 0.6071 |
Echinococcus multilocularis | tubulin subunit TubB | 0.0027 | 0.071 | 0.0692 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Plasmodium falciparum | tubulin beta chain | 0.0033 | 0.1158 | 1 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.0019 | 0.0172 | 0.0555 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0583 | 0.1619 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0057 | 0.2766 | 1 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0057 | 0.2766 | 1 |
Brugia malayi | Tubulin alpha chain | 0.0027 | 0.071 | 0.2279 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0583 | 0.2054 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0062 | 0.3052 | 0.3039 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Loa Loa (eye worm) | tubulin beta-4 chain | 0.0033 | 0.1158 | 0.3793 |
Echinococcus multilocularis | tubulin alpha chain | 0.0027 | 0.071 | 0.0692 |
Entamoeba histolytica | iron-sulfur flavoprotein, putative | 0.0021 | 0.0294 | 0.0955 |
Brugia malayi | tubulin alpha chain - mouse | 0.0027 | 0.071 | 0.2279 |
Echinococcus multilocularis | tubulin epsilon chain | 0.0019 | 0.0172 | 0.0153 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.2766 | 0.2752 |
Echinococcus multilocularis | tubulin alpha | 0.0019 | 0.0172 | 0.0153 |
Trichomonas vaginalis | FMN-dependent NADH-azoreductase, putative | 0.0021 | 0.0294 | 0.0663 |
Trypanosoma brucei | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Trypanosoma cruzi | tubulin gamma chain | 0.0019 | 0.0172 | 0.0555 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0162 | 0.5 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.145 | 0.521 |
Giardia lamblia | Alpha-tubulin | 0.0027 | 0.071 | 0.1265 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0057 | 0.2766 | 1 |
Loa Loa (eye worm) | alpha-tubulin | 0.0027 | 0.071 | 0.2327 |
Brugia malayi | jmjC domain containing protein | 0.0062 | 0.3052 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0019 | 0.0063 |
Schistosoma mansoni | jumonji domain containing protein | 0.0062 | 0.3052 | 0.3039 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0033 | 0.1158 | 0.1141 |
Giardia lamblia | Beta tubulin | 0.0033 | 0.1158 | 0.2316 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0027 | 0.071 | 0.0692 |
Brugia malayi | Cytochrome P450 family protein | 0.0057 | 0.2766 | 0.9056 |
Echinococcus multilocularis | beta tubulin | 0.0033 | 0.1158 | 0.1141 |
Leishmania major | gamma-tubulin | 0.0019 | 0.0172 | 0.0555 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0027 | 0.071 | 0.0692 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Schistosoma mansoni | tubulin subunit beta | 0.0033 | 0.1158 | 0.1141 |
Entamoeba histolytica | hypothetical protein | 0.0021 | 0.0294 | 0.0955 |
Echinococcus granulosus | tubulin subunit beta | 0.0033 | 0.1158 | 0.1141 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.0082 | 0.4429 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.145 | 0.1434 |
Schistosoma mansoni | alpha tubulin | 0.0027 | 0.071 | 0.0692 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0057 | 0.2766 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Schistosoma mansoni | tubulin subunit beta | 0.0033 | 0.1158 | 0.1141 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.0583 | 0.3221 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Echinococcus granulosus | alpha tubulin | 0.0027 | 0.071 | 0.0692 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0057 | 0.2766 | 1 |
Trypanosoma brucei | epsilon tubulin | 0.0019 | 0.0172 | 0.0555 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0057 | 0.2766 | 1 |
Plasmodium vivax | tubulin gamma chain, putative | 0.0019 | 0.0172 | 0.134 |
Echinococcus granulosus | peroxisome assembly protein 26 | 0.0027 | 0.071 | 0.0692 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0057 | 0.2766 | 1 |
Giardia lamblia | Alpha-tubulin | 0.0027 | 0.071 | 0.1265 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0057 | 0.2766 | 1 |
Schistosoma mansoni | tubulin subunit alpha | 0.0027 | 0.071 | 0.0692 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0057 | 0.2766 | 1 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0057 | 0.2766 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0027 | 0.071 | 0.1604 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0583 | 0.1912 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.0583 | 0.1832 |
Echinococcus granulosus | tubulin subunit TubB | 0.0027 | 0.071 | 0.0692 |
Leishmania major | cytochrome p450-like protein | 0.0057 | 0.2766 | 1 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0057 | 0.2766 | 1 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0057 | 0.2766 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.3052 | 1 |
Brugia malayi | Inositol-1 | 0.0038 | 0.145 | 0.4718 |
Echinococcus multilocularis | tubulin alpha chain | 0.0027 | 0.071 | 0.0692 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.0583 | 0.1619 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0294 | 0.0663 |
Trypanosoma brucei | beta tubulin | 0.0019 | 0.0172 | 0.0555 |
Plasmodium falciparum | tubulin epsilon chain, putative | 0.0019 | 0.0172 | 0.134 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.0027 | 0.071 | 0.0692 |
Echinococcus multilocularis | tubulin alpha chain | 0.0027 | 0.071 | 0.0692 |
Loa Loa (eye worm) | alpha-tubulin | 0.0027 | 0.071 | 0.2327 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.0082 | 0.4429 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0057 | 0.2766 | 1 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0057 | 0.2766 | 0.9062 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Entamoeba histolytica | tubulin alpha-1 chain | 0.0027 | 0.071 | 0.4212 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.145 | 0.3274 |
Trypanosoma brucei | epsilon tubulin | 0.0019 | 0.0172 | 0.0555 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0057 | 0.2766 | 1 |
Loa Loa (eye worm) | cytochrome P450 | 0.0057 | 0.2766 | 0.9062 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0019 | 0.0165 | 0.0541 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0019 | 0.0165 | 0.0373 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0057 | 0.2766 | 1 |
Trypanosoma brucei | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0082 | 0.4429 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0062 | 0.3052 | 0.689 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0057 | 0.2766 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0019 | 0.0063 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.0583 | 0.1619 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.0082 | 0.4429 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.0583 | 0.1619 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0057 | 0.2766 | 1 |
Giardia lamblia | Beta tubulin | 0.0033 | 0.1158 | 0.2316 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0082 | 0.4429 | 1 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0162 | 0.0531 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0057 | 0.2766 | 1 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Brugia malayi | Tubulin alpha-2 chain | 0.0027 | 0.071 | 0.2279 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0082 | 0.4429 | 1 |
Echinococcus granulosus | tubulin alpha chain | 0.0027 | 0.071 | 0.0692 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Echinococcus granulosus | tubulin alpha chain | 0.0027 | 0.071 | 0.0692 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0583 | 0.1861 |
Toxoplasma gondii | alpha tubulin TUBA1 | 0.0027 | 0.071 | 0.2516 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0057 | 0.2766 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0057 | 0.2766 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.145 | 0.521 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0019 | 0.0172 | 0.0388 |
Onchocerca volvulus | 0.0025 | 0.0583 | 0.5 | |
Echinococcus multilocularis | 0.0057 | 0.2766 | 0.2752 | |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.145 | 0.521 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Trypanosoma brucei | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Mycobacterium leprae | putative cytochrome p450 | 0.0057 | 0.2766 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0033 | 0.1158 | 0.2614 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0082 | 0.4429 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0057 | 0.2766 | 0.9062 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Brugia malayi | Tubulin beta-1 chain | 0.0033 | 0.1158 | 0.3754 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0033 | 0.1158 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.071 | 0.2327 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0583 | 0.2054 |
Schistosoma mansoni | tubulin subunit alpha | 0.0027 | 0.071 | 0.0692 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0057 | 0.2766 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0583 | 0.1861 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0027 | 0.071 | 0.2327 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.0027 | 0.071 | 0.0692 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0033 | 0.1158 | 0.1141 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0057 | 0.2766 | 1 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0027 | 0.071 | 0.0692 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Loa Loa (eye worm) | tubulin beta chain | 0.0033 | 0.1158 | 0.3793 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.0583 | 0.1619 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0038 | 0.145 | 0.4947 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0162 | 0.0255 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0033 | 0.1158 | 0.2614 |
Trypanosoma brucei | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0294 | 0.0663 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0033 | 0.1158 | 0.1141 |
Echinococcus granulosus | tubulin alpha chain | 0.0027 | 0.071 | 0.0692 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0034 | 0.1185 | 0.2755 |
Echinococcus granulosus | tubulin epsilon chain | 0.0019 | 0.0172 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0162 | 0.0531 |
Brugia malayi | Cytochrome P450 family protein | 0.0057 | 0.2766 | 0.9056 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0294 | 0.0663 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Leishmania major | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0033 | 0.1158 | 0.1141 |
Brugia malayi | jmjC domain containing protein | 0.0062 | 0.3052 | 1 |
Echinococcus granulosus | beta tubulin | 0.0033 | 0.1158 | 0.1141 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0021 | 0.0294 | 0.0663 |
Echinococcus multilocularis | tubulin beta 1 chain | 0.0033 | 0.1158 | 0.1141 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0294 | 0.0663 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0294 | 0.0663 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0583 | 0.1619 |
Loa Loa (eye worm) | BEN-1 protein | 0.0033 | 0.1158 | 0.3793 |
Echinococcus multilocularis | geminin | 0.0165 | 1 | 1 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0027 | 0.071 | 0.2327 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0057 | 0.2766 | 1 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0033 | 0.1158 | 0.2614 |
Trypanosoma brucei | beta tubulin | 0.0033 | 0.1158 | 0.4145 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Schistosoma mansoni | tubulin subunit beta | 0.0033 | 0.1158 | 0.1141 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0162 | 0.1255 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0038 | 0.145 | 0.5 |
Schistosoma mansoni | tubulin subunit epsilon | 0.0019 | 0.0172 | 0.0153 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0057 | 0.2766 | 1 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0057 | 0.2766 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0162 | 0.0531 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0583 | 0.2054 |
Leishmania major | alpha tubulin | 0.0027 | 0.071 | 0.2516 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0057 | 0.2766 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0057 | 0.2766 | 1 |
Trichomonas vaginalis | modulator of drug activity B, putative | 0.0021 | 0.0294 | 0.0663 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0057 | 0.2766 | 1 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0057 | 0.2766 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.0294 | 0.0663 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0033 | 0.1158 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0162 | 0.0531 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | > 50 ug ml-1 | Antibacterial activity against Escherichia coli after 24 hrs by MTT assay | ChEMBL. | 17977623 |
MIC (functional) | > 50 ug ml-1 | Antifungal activity against Candida albicans after 48 hrs by MTT assay | ChEMBL. | 17977623 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.