Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0512 | 0.0512 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0.2275 | 0.6011 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0042 | 0.0856 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0715 | 0.7919 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0129 | 0.3175 | 0.3964 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.2275 | 0.2275 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0375 | 0.4192 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0042 | 0.0856 | 1 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0023 | 0.0375 | 0.405 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0232 | 0.591 | 1 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0023 | 0.0375 | 0.4378 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0023 | 0.0375 | 0.099 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.001 | 0.0028 | 0.0216 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0569 | 0.0542 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0569 | 0.0569 |
Schistosoma mansoni | hypothetical protein | 0.0309 | 0.7968 | 0.7968 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0525 | 0.0625 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0042 | 0.0856 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0042 | 0.0856 | 0.083 |
Schistosoma mansoni | ap endonuclease | 0.0042 | 0.0856 | 0.0856 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0512 | 0.1353 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0023 | 0.0375 | 0.0436 |
Brugia malayi | hypothetical protein | 0.0089 | 0.2107 | 0.5567 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.1322 | 0.163 |
Brugia malayi | hypothetical protein | 0.0035 | 0.069 | 0.1824 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.0891 | 1 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0042 | 0.0856 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.001 | 0.0028 | 0.0075 |
Onchocerca volvulus | 0.0029 | 0.0525 | 0.0039 | |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0715 | 0.189 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0715 | 0.6936 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0023 | 0.0375 | 0.3884 |
Onchocerca volvulus | 0.0152 | 0.3785 | 1 | |
Brugia malayi | Bromodomain containing protein | 0.0032 | 0.0607 | 0.1604 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0.2275 | 0.283 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.0716 | 0.069 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0048 | 0.1024 | 0.1254 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0512 | 0.3904 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0042 | 0.0856 | 0.9591 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0715 | 0.0865 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0023 | 0.0375 | 0.0347 |
Loa Loa (eye worm) | TAR-binding protein | 0.0129 | 0.3175 | 0.3964 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0715 | 0.0689 |
Schistosoma mansoni | ap endonuclease | 0.0042 | 0.0856 | 0.0856 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.081 | 0.0784 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0569 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0715 | 0.0865 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0716 | 0.1893 |
Echinococcus multilocularis | tar DNA binding protein | 0.0129 | 0.3175 | 0.3156 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.0796 | 0.9253 |
Brugia malayi | PHD-finger family protein | 0.0011 | 0.0044 | 0.0117 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0715 | 0.8296 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0094 | 0.2243 | 0.2221 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.1392 | 0.1392 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0715 | 0.1168 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0146 | 0.3626 | 0.3626 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0318 | 0.3496 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0023 | 0.0375 | 0.2857 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.069 | 0.6915 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.1312 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0715 | 0.8296 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.069 | 0.069 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0512 | 0.0609 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0715 | 0.1168 |
Schistosoma mansoni | ran | 0.0021 | 0.0318 | 0.0318 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.069 | 0.6915 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0044 | 0.002 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0018 | 0.0236 | 0.0624 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0309 | 0.7968 | 1 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0318 | 0.029 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0715 | 0.1168 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0318 | 0.3496 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0318 | 0.0365 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0023 | 0.0375 | 0.099 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.2107 | 0.2618 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0715 | 0.0715 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0512 | 0.0512 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0094 | 0.2243 | 0.2221 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0715 | 0.0715 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0715 | 0.8296 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.069 | 0.0664 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0715 | 0.0689 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.2107 | 0.2618 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0715 | 0.8296 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0715 | 0.8296 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0142 | 0.3518 | 0.3499 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.069 | 0.0664 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.2275 | 0.2253 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0521 | 0.3971 |
Trichomonas vaginalis | chaperonin, putative | 0.0023 | 0.0375 | 0.0996 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0715 | 0.1168 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.081 | 0.0784 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0521 | 0.0494 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0042 | 0.0856 | 0.2263 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0512 | 0.0485 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.0891 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0715 | 0.0865 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0129 | 0.3175 | 0.839 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0715 | 0.0865 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0042 | 0.0856 | 0.083 |
Echinococcus granulosus | tar DNA binding protein | 0.0129 | 0.3175 | 0.3156 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0715 | 0.0865 |
Echinococcus granulosus | snurportin 1 | 0.0309 | 0.7968 | 0.7963 |
Brugia malayi | jmjC domain containing protein | 0.0094 | 0.2243 | 0.5926 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0716 | 0.0716 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1056 | 0.1294 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.2275 | 0.2253 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3175 | 0.3175 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0715 | 0.8352 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0318 | 0.2422 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0042 | 0.0856 | 0.5 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0512 | 0.0485 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0715 | 0.1168 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0042 | 0.0856 | 0.9398 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0042 | 0.0856 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0715 | 0.0865 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0375 | 0.107 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0521 | 0.6084 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0512 | 0.3608 |
Brugia malayi | TAR-binding protein | 0.0129 | 0.3175 | 0.839 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.0891 | 0.679 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0042 | 0.0856 | 0.1408 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0715 | 0.1168 |
Echinococcus granulosus | peregrin | 0.0032 | 0.0607 | 0.058 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0375 | 0.4192 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0042 | 0.0856 | 0.1043 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0318 | 0.3711 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3175 | 0.3175 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.3785 | 0.4731 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0017 | 0.0192 | 0.0192 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0318 | 0.3208 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.1731 | 0.1731 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0042 | 0.0856 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0525 | 0.1387 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0023 | 0.0375 | 0.4185 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0715 | 0.189 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.2275 | 0.2275 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0042 | 0.0856 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0715 | 0.8296 |
Onchocerca volvulus | 0.0036 | 0.0715 | 0.0621 | |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0715 | 1 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0011 | 0.0041 | 0.0013 |
Brugia malayi | RNA, U transporter 1 | 0.0082 | 0.194 | 0.5126 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0715 | 0.8296 |
Brugia malayi | Cytochrome P450 family protein | 0.001 | 0.0028 | 0.0075 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.0796 | 0.8877 |
Brugia malayi | Cytochrome P450 family protein | 0.001 | 0.0028 | 0.0075 |
Brugia malayi | Cytochrome P450 family protein | 0.0048 | 0.1024 | 0.2706 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0146 | 0.3626 | 0.3608 |
Trypanosoma brucei | cytochrome P450, putative | 0.001 | 0.0028 | 0.0331 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0521 | 0.0521 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0715 | 0.6936 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0375 | 0.1006 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0521 | 0.6084 |
Echinococcus multilocularis | snurportin 1 | 0.0309 | 0.7968 | 0.7963 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0023 | 0.0375 | 0.0996 |
Brugia malayi | cytochrome P450 | 0.001 | 0.0028 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0521 | 0.062 |
Onchocerca volvulus | 0.0036 | 0.0715 | 0.0621 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.2275 | 0.2253 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0521 | 0.0494 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0042 | 0.0856 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.2275 | 0.2275 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0512 | 0.3904 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0042 | 0.0856 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0715 | 0.1168 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0569 | 0.0542 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0521 | 0.1377 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0715 | 0.1168 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0023 | 0.0375 | 0.0347 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.0891 | 0.679 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0715 | 0.1168 |
Schistosoma mansoni | hypothetical protein | 0.0386 | 1 | 1 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0715 | 0.189 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.001 | 0.0028 | 0.0331 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0715 | 0.189 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0512 | 0.5746 |
Schistosoma mansoni | hypothetical protein | 0.0386 | 1 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0715 | 0.1168 |
Onchocerca volvulus | 0.0036 | 0.0715 | 0.0621 | |
Loa Loa (eye worm) | RNA binding protein | 0.0129 | 0.3175 | 0.3964 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0715 | 0.6936 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0672 | 0.0646 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.0891 | 0.0865 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0375 | 0.1006 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0715 | 0.5452 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0023 | 0.0375 | 0.0375 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0715 | 0.6936 |
Toxoplasma gondii | exonuclease III APE | 0.0042 | 0.0856 | 0.6527 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0512 | 0.0609 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0023 | 0.0375 | 0.1059 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0715 | 1 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0028 | 0.0028 |
Brugia malayi | hypothetical protein | 0.0152 | 0.3785 | 1 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0146 | 0.3626 | 0.9581 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.2275 | 0.2253 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0715 | 0.6936 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3175 | 0.3175 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3175 | 0.3175 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0023 | 0.0375 | 0.0375 |
Loa Loa (eye worm) | acetyltransferase | 0.0146 | 0.3626 | 0.4531 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0715 | 0.0865 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0023 | 0.0375 | 0.1059 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0023 | 0.0375 | 0.4185 |
Schistosoma mansoni | eyes absent homolog | 0.0089 | 0.2107 | 0.2107 |
Echinococcus multilocularis | peregrin | 0.0032 | 0.0607 | 0.058 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0318 | 0.3345 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0023 | 0.0375 | 0.0375 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0318 | 0.3496 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.0891 | 1 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0318 | 0.084 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0525 | 0.0525 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.069 | 0.6915 |
Schistosoma mansoni | cytochrome P450 | 0.001 | 0.0028 | 0.0028 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0521 | 0.5856 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0521 | 0.5617 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0715 | 0.8296 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.069 | 0.6915 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0715 | 0.6936 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0011 | 0.0041 | 0.0013 |
Schistosoma mansoni | ran | 0.0021 | 0.0318 | 0.0318 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0318 | 0.029 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3175 | 0.3175 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0716 | 0.0716 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0512 | 0.5511 |
Brugia malayi | RNA binding protein | 0.0129 | 0.3175 | 0.839 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.069 | 0.069 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0.0796 | 0.8877 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0375 | 0.1006 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0715 | 0.0865 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0716 | 0.0866 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0042 | 0.0856 | 0.9398 |
Echinococcus multilocularis | geminin | 0.0386 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 6 % | Displacement of fluorescein-labeled estradiol from human recombinant ERbeta at 0.2 uM by fluorescence polarization assay | ChEMBL. | 19356928 |
Activity (binding) | = 13 % | Displacement of fluorescein-labeled estradiol from human recombinant ERbeta at 1 uM by fluorescence polarization assay | ChEMBL. | 19356928 |
Activity (binding) | = 42 % | Displacement of fluorescein-labeled estradiol from human recombinant ERbeta at 5 uM by fluorescence polarization assay | ChEMBL. | 19356928 |
Activity (binding) | = 42 % | Displacement of fluorescein-labeled estradiol from human recombinant ERalpha at 0.2 uM by fluorescence polarization assay | ChEMBL. | 19356928 |
Activity (binding) | = 61 % | Displacement of fluorescein-labeled estradiol from human recombinant ERalpha at 1 uM by fluorescence polarization assay | ChEMBL. | 19356928 |
Activity (binding) | = 95 % | Displacement of fluorescein-labeled estradiol from human recombinant ERalpha at 5 uM by fluorescence polarization assay | ChEMBL. | 19356928 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.