Detailed information for compound 1002698

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 335.421 | Formula: C16H21N3O3S
  • H donors: 1 H acceptors: 2 LogP: 3.38 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOCCOC(=O)c1c(SC)nn(c1N)c1ccc(cc1)C
  • InChi: 1S/C16H21N3O3S/c1-4-21-9-10-22-16(20)13-14(17)19(18-15(13)23-3)12-7-5-11(2)6-8-12/h5-8H,4,9-10,17H2,1-3H3
  • InChiKey: SPQXLJAOPWOVAV-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0036 0.0148 0.0817
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0064 0.0164
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0016 0.0022 0.0221
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0038 0.0162 1
Loa Loa (eye worm) Ulp1 protease 0.0015 0.0017 0.0007
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0015 0.0091
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0007
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0015 0.0015 0.0146
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.016 0.0483
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0064 0.1285
Loa Loa (eye worm) CXXC zinc finger family protein 0.0088 0.0483 0.156
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.016 0.109
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.0392 0.1259
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0015 0.0087
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.016 0.0891
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0016 0.0022 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0201
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0061 0.0308 0.0977
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0015 0.0087
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0308 1
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0016 0.0022 0.0136
Loa Loa (eye worm) hypothetical protein 0.0038 0.0162 0.0488
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0015 0.0017 0.0146
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.016 0.0483
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0016 0.0022 0.0136
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0148 0.101
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0016 0.0022 0.0221
Plasmodium vivax SET domain protein, putative 0.0036 0.0148 0.4531
Brugia malayi Muscleblind-like protein 0.0169 0.0997 0.3277
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0171 0.0291
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0015 0.0017 0.0168
Echinococcus granulosus muscleblind protein 0.0169 0.0997 0.1832
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0159 0.0885
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0016 0.0022 0.0136
Trypanosoma brucei unspecified product 0.0015 0.0019 0.0107
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0064 0.0617
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0061 0.0308 0.7765
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0016 0.0022 0.0136
Mycobacterium leprae putative cytochrome p450 0.0016 0.0022 0.0284
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.0159 0.048
Toxoplasma gondii exonuclease III APE 0.0061 0.0308 0.2944
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0016 0.0022 0.0136
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0064 0.1285
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0037 0.0158 0.0266
Schistosoma mansoni microtubule-associated protein tau 0.0779 0.4896 0.9104
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0128 0.021
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0061 0.0308 0.2988
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0151 0.0885 0.2902
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0016 0.0022 0.0221
Loa Loa (eye worm) hypothetical protein 0.008 0.0433 0.1394
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0061 0.0308 0.0546
Echinococcus multilocularis fetal alzheimer antigen, falz 0.003 0.011 0.0095
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0015 0.0017 0.0014
Brugia malayi PHD-finger family protein 0.0032 0.0126 0.0371
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0016 0.0022 0.0221
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0243 0.1664
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0174 0.1031 0.1917
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0048 0.0201
Trypanosoma brucei ISWI complex protein 0.0017 0.0027 0.0319
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0015 0.0017 0.0022
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0064 0.1361
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0151 0.0885 0.0871
Mycobacterium leprae Conserved hypothetical protein 0.0016 0.0022 0.0284
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0064 0.1655
Echinococcus granulosus pyruvate kinase 0.0019 0.0043 0.0052
Brugia malayi Calcitonin receptor-like protein seb-1 0.0117 0.067 0.2185
Giardia lamblia Pyruvate kinase 0.0037 0.0159 0.4869
Echinococcus granulosus pyruvate kinase 0.0037 0.0159 0.0268
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0007
Echinococcus granulosus fetal alzheimer antigen falz 0.003 0.011 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0201
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0243 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0151 0.0885 0.1622
Brugia malayi beta-lactamase family protein 0.0038 0.016 0.0483
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0048 0.0201
Entamoeba histolytica pyruvate kinase, putative 0.0026 0.0087 0.0841
Echinococcus granulosus geminin 0.0199 0.1194 0.2199
Echinococcus multilocularis pyruvate kinase 0.0019 0.0043 0.0028
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0022 0.0022
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.0159 0.3811
Onchocerca volvulus 0.0088 0.0483 0.2877
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0016 0.0022 0.0257
Schistosoma mansoni bromodomain containing protein 0.0074 0.0394 0.0733
Schistosoma mansoni tar DNA-binding protein 0.0484 0.3013 0.5602
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.016 0.4944
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0201
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0148 0.101
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0061 0.0308 0.7784
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.016 0.027
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0015 0.0017 0.0168
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0016 0.0022 0.0221
Echinococcus granulosus pyruvate kinase 0.0037 0.0159 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0201
Loa Loa (eye worm) hypothetical protein 0.0038 0.016 0.0483
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0064 0.0162
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0151 0.0885 0.1645
Loa Loa (eye worm) hypothetical protein 0.0038 0.0162 0.0488
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0015 0.0087
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0117 0.067 0.2185
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0015 0.0017 0.0022
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0015 0.0087
Schistosoma mansoni zinc finger protein 0.0026 0.0089 0.0166
Leishmania major cytochrome p450-like protein 0.0016 0.0022 0.0257
Onchocerca volvulus 0.0269 0.1641 1
Schistosoma mansoni tar DNA-binding protein 0.0484 0.3013 0.5602
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0015 0.0017 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0016 0.0022 0.0136
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0016 0.0022 0.0221
Echinococcus multilocularis pyruvate kinase 0.0037 0.0159 0.0144
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.016 0.109
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0016 0.0022 0.0136
Schistosoma mansoni ap endonuclease 0.0061 0.0308 0.0573
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0068 0.0053
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0015 0.0017 0.0014
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0159 0.3865
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0022 0.0221
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0016 0.0022 0.0221
Loa Loa (eye worm) hypothetical protein 0.0038 0.0162 0.0488
Plasmodium vivax sentrin-specific protease 1, putative 0.0015 0.0017 0.0076
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0194 0.0179
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.016 0.3892
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0015 0.0017 0.0014
Loa Loa (eye worm) RNA binding protein 0.0484 0.3013 1
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0308 0.1802
Schistosoma mansoni pyruvate kinase 0.0037 0.0159 0.0295
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.0159 0.6307
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0064 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0201
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0051 0.0243 0.7782
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0174 0.1031 1
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0015 0.0017 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0016 0.0022 0.0136
Entamoeba histolytica acyl-coA synthetase, putative 0.0051 0.0243 0.2358
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0017 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0267 0.0496
Brugia malayi beta-lactamase family protein 0.0038 0.016 0.0483
Trichomonas vaginalis set domain proteins, putative 0.0269 0.1641 1
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0016 0.0022 0.0221
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0015 0.0017 0.0146
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0016 0.0022 0.0136
Trypanosoma brucei SUMO1/Ulp2, putative 0.0015 0.0017 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0064 0.1285
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0016 0.0022 0.0136
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0201
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.0159 0.048
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0037 0.0158 0.0266
Loa Loa (eye worm) hypothetical protein 0.0051 0.0243 0.0761
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0148 0.101
Schistosoma mansoni hypothetical protein 0.0854 0.5378 1
Plasmodium vivax pyruvate kinase, putative 0.0037 0.0159 0.4908
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0064 0.0425
Brugia malayi TAR-binding protein 0.0484 0.3013 1
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0015 0.0091
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0064 0.0425
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0051 0.0243 0.7782
Echinococcus granulosus dna polymerase eta 0.0022 0.0064 0.009
Echinococcus granulosus histone lysine methyltransferase setb 0.0054 0.0267 0.047
Brugia malayi beta-lactamase 0.0038 0.016 0.0483
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0064 0.1285
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0015 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0159 0.048
Brugia malayi Bromodomain containing protein 0.0042 0.0188 0.0576
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0019 0.0107
Loa Loa (eye worm) hypothetical protein 0.0051 0.0243 0.0761
Toxoplasma gondii histone lysine methyltransferase SET1 0.0171 0.101 1
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0015 0.0017 0.0007
Mycobacterium tuberculosis Conserved protein 0.0038 0.016 0.109
Echinococcus multilocularis GPCR, family 2 0.0037 0.0158 0.0143
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0102 0.0087
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0064 0.1361
Trypanosoma cruzi hypothetical protein 0.0015 0.0017 0.0146
Plasmodium vivax sentrin-specific protease 2, putative 0.0015 0.0017 0.0076
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0015 0.0028
Mycobacterium tuberculosis Conserved protein 0.0038 0.016 0.109
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0148 0.1334
Echinococcus multilocularis geminin 0.0199 0.1194 0.1181
Leishmania major cytochrome p450-like protein 0.0016 0.0022 0.0257
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.016 0.3892
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0015 0.0087
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0243 0.6077
Leishmania major cytochrome p450-like protein 0.0016 0.0022 0.0257
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0392 1
Echinococcus granulosus dna polymerase kappa 0.0022 0.0064 0.009
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0016 0.0022 0.0221
Brugia malayi Bromodomain containing protein 0.0087 0.0476 0.1538
Trichomonas vaginalis sentrin/sumo-specific protease, senp8, putative 0.0015 0.0017 0.0014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0148 0.101
Loa Loa (eye worm) hypothetical protein 0.0052 0.025 0.0784
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.0162 0.1101
Leishmania major DNA polymerase eta, putative 0.0022 0.0064 0.1361
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0015 0.0017 0.0014
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0015 0.0017 0.0014
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0369 0.0355
Brugia malayi CXXC zinc finger family protein 0.0088 0.0483 0.156
Echinococcus multilocularis zinc finger protein 0.0026 0.0089 0.0074
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0061 0.0308 1
Mycobacterium ulcerans hypothetical protein 0.0051 0.0243 0.7782
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0068 0.0126
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0243 0.7782
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0243 0.0761
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0201
Giardia lamblia DINP protein human, muc B family 0.0022 0.0064 0.1591
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0188 0.1121 0.2085
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0267 0.0496
Chlamydia trachomatis pyruvate kinase 0.0037 0.0159 0.9819
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0016 0.0022 0.0136
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0037 0.0158 0.0475
Loa Loa (eye worm) hypothetical protein 0.0169 0.0997 0.3277
Echinococcus granulosus sentrin specific protease 7 0.0174 0.1031 0.1894
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0051 0.0243 0.7782
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0068 0.0053
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0044 0.0095
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0369 0.066
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0048 0.0201
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0061 0.0308 0.7784
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0015 0.0017 0.0014
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0015 0.0091
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0016 0.0022 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0019 0.0107
Trichomonas vaginalis helicase, putative 0.002 0.0048 0.0201
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.016 0.0145
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0051 0.0243 0.7782
Echinococcus granulosus dnaJ subfamily B 0.0854 0.5378 1
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0015 0.0087
Loa Loa (eye worm) hypothetical protein 0.0077 0.0414 0.1331
Leishmania major hypothetical protein, conserved 0.0038 0.016 0.3892
Trypanosoma brucei unspecified product 0.0015 0.0019 0.0107
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.016 0.109
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0016 0.0022 0.0171
Mycobacterium tuberculosis Conserved protein 0.0038 0.016 0.109
Mycobacterium ulcerans beta-lactamase 0.0038 0.016 0.4944
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0022 0.0171
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.016 0.4944
Mycobacterium ulcerans hypothetical protein 0.0038 0.016 0.4944
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0064 0.0049
Onchocerca volvulus 0.0038 0.016 0.0891
Schistosoma mansoni DNA polymerase eta 0.0022 0.0064 0.0118
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0022 0.0257
Echinococcus multilocularis tar DNA binding protein 0.0484 0.3013 0.3002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0064 0.1361
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0151 0.0885 0.1622
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.016 0.109
Echinococcus granulosus microtubule associated protein 2 0.0779 0.4896 0.9102
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0392 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0037 0.0158 0.0143
Toxoplasma gondii ABC1 family protein 0.0038 0.016 0.1456
Loa Loa (eye worm) hypothetical protein 0.0042 0.0188 0.0577
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0016 0.0022 0.0221
Echinococcus granulosus sentrin specific protease 1 0.0015 0.0017 0.0004
Brugia malayi Pre-SET motif family protein 0.0237 0.1433 0.4731
Schistosoma mansoni hypothetical protein 0.0037 0.0158 0.0293
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0015 0.0017 0.0014
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.016 0.0891
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0016 0.0022 0.0136
Schistosoma mansoni hypothetical protein 0.0199 0.1194 0.2221
Schistosoma mansoni tar DNA-binding protein 0.0484 0.3013 0.5602
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0015 0.0091
Loa Loa (eye worm) hypothetical protein 0.0038 0.0162 0.0488
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.0392 0.0378
Plasmodium falciparum acyl-CoA synthetase 0.0038 0.0162 0.5242
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.016 0.0297
Plasmodium vivax acyl-CoA synthetase, putative 0.0038 0.0162 0.4997
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.003 0.011 0.0204
Echinococcus multilocularis dna polymerase eta 0.0022 0.0064 0.0049
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0061 0.0308 0.7784
Onchocerca volvulus 0.0051 0.0243 0.1403
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0308 0.1802
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0064 0.0298
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0016 0.0022 0.0136
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0016 0.0022 0.0136
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Brugia malayi Pre-SET motif family protein 0.0036 0.0148 0.0443
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0022 0.0257
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0243 0.6077
Brugia malayi exodeoxyribonuclease III family protein 0.0061 0.0308 0.0977
Giardia lamblia Pyruvate kinase 0.0019 0.0043 0.0875
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0068 0.0099
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0016 0.0022 0.0136
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.0159 0.1083
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0016 0.0022 0.0221
Brugia malayi Cytochrome P450 family protein 0.0059 0.0294 0.0932
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0051 0.0243 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0064 0.1285
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0061 0.0308 0.0293
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0159 0.0885
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0194 0.0333
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0007
Echinococcus multilocularis cpg binding protein 0.0095 0.0528 0.0514
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.016 0.109
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0016 0.0022 0.0221
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0117 0.067 0.2185
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.0392 0.1259
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0064 0.1655
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0015 0.049
Brugia malayi cytochrome P450 0.0016 0.0022 0.0022
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0243 0.7782
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.0087 0.0239
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0016 0.0022 0.0136
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0102 0.0162
Brugia malayi RNA binding protein 0.0484 0.3013 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0151 0.0885 0.1645
Schistosoma mansoni hypothetical protein 0.008 0.0433 0.0805
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0151 0.0885 0.2902
Trypanosoma brucei pyruvate kinase 1 0.0037 0.0159 0.3811
Schistosoma mansoni zinc finger protein 0.0017 0.0027 0.005
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.005
Schistosoma mansoni ap endonuclease 0.0061 0.0308 0.0573
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.0392 0.073
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0159 0.3865
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0016 0.0022 0.0136
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0037 0.0158 0.0143
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0064 0.1285
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0064 0.1285
Mycobacterium ulcerans lipase LipD 0.0038 0.016 0.4944
Schistosoma mansoni hypothetical protein 0.0016 0.0022 0.004
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0015 0.0017 0.0014
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.016 0.0297
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0064 0.0049
Onchocerca volvulus 0.0038 0.016 0.0891
Loa Loa (eye worm) beta-lactamase 0.0038 0.016 0.0483
Loa Loa (eye worm) hypothetical protein 0.0038 0.016 0.0483
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0048 0.0201
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0308 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0484 0.3013 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0039 0.0073
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0064 0.0118
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0015 0.0017 0.0007
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0015 0.0091
Leishmania major pyruvate kinase 0.0037 0.0159 0.3865
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0016 0.0022 0.0221
Trichomonas vaginalis esterase, putative 0.0038 0.016 0.0891
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0148 0.0133
Loa Loa (eye worm) hypothetical protein 0.0026 0.0087 0.0239
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0016 0.0022 0.0136
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0048 0.0201
Schistosoma mansoni hypothetical protein 0.0037 0.0158 0.0293
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0064 0.1285
Echinococcus granulosus GPCR family 2 0.0037 0.0158 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0201
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0022 0.0257
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0016 0.0022 0.0136
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0237 0.1433 0.4731
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0015 0.0087
Echinococcus multilocularis pyruvate kinase 0.0019 0.0043 0.0028
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.0159 0.1445
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.0392 0.0704
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0064 0.009
Echinococcus multilocularis muscleblind protein 1 0.0169 0.0997 0.0984
Loa Loa (eye worm) Ulp1 protease 0.0015 0.0017 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0064 0.1285
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0064 0.1361
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0054 0.0267 0.084
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0015 0.0017 0.0032
Mycobacterium tuberculosis Possible penicillin-binding protein 0.024 0.1451 1
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0015 0.0091
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0243 0.6077
Trypanosoma brucei unspecified product 0.0022 0.0064 0.1285
Loa Loa (eye worm) hypothetical protein 0.0038 0.016 0.0483
Echinococcus granulosus tar DNA binding protein 0.0484 0.3013 0.559
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0051 0.0243 0.1664
Loa Loa (eye worm) cytochrome P450 0.0016 0.0022 0.0022
Echinococcus multilocularis pyruvate kinase 0.0037 0.0159 0.0144
Echinococcus multilocularis dnaJ subfamily B 0.0854 0.5378 0.5371
Echinococcus granulosus cpg binding protein 0.0095 0.0528 0.0957
Treponema pallidum exodeoxyribonuclease (exoA) 0.0061 0.0308 0.5
Schistosoma mansoni hypothetical protein 0.0037 0.0158 0.0293
Echinococcus granulosus sentrin specific protease 8 0.0015 0.0017 0.0004
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0016 0.0022 0.0221
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0016 0.0022 0.0221
Plasmodium falciparum sentrin-specific protease 1 0.0015 0.0017 0.0562
Leishmania major hypothetical protein, conserved 0.0017 0.0027 0.0403
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0015 0.0017 0.0007
Brugia malayi Cytochrome P450 family protein 0.0016 0.0022 0.0022
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0016 0.0022 0.0221
Trypanosoma cruzi ISWI complex protein 0.0017 0.0027 0.0403
Schistosoma mansoni tar DNA-binding protein 0.0484 0.3013 0.5602
Schistosoma mansoni hypothetical protein 0.0037 0.0158 0.0293
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.0043 0.0945
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.0392 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0064 0.1285
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.016 0.109
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0159 0.0885
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0015 0.0017 0.0168
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0171 0.0156
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0151 0.0885 0.1645
Toxoplasma gondii cytochrome p450 superfamily protein 0.0016 0.0022 0.0065
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0022 0.0257
Brugia malayi latrophilin 2 splice variant baaae 0.008 0.0433 0.1394
Echinococcus granulosus zinc finger protein 0.0026 0.0089 0.0138
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0064 0.0162
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0015 0.0017 0.0032
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0015 0.0017 0.0168
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.016 0.0891
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0038 0.0162 0.4997
Loa Loa (eye worm) hypothetical protein 0.0169 0.0997 0.3277
Mycobacterium ulcerans pyruvate kinase 0.0037 0.0159 0.4908
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0064 0.0162
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0064 0.1285
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0243 0.2358
Echinococcus multilocularis muscleblind protein 0.0169 0.0997 0.0984
Loa Loa (eye worm) hypothetical protein 0.0037 0.0158 0.0475
Trypanosoma cruzi ISWI complex protein 0.0017 0.0027 0.0403
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0039 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0019 0.0107
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0243 0.0761
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0151 0.0885 0.0871
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0159 0.048
Loa Loa (eye worm) hypothetical protein 0.0051 0.0243 0.0761
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0016 0.0022 0.0221
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0048 0.0201
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0016 0.0022 0.0136
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0048 0.0201
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0015 0.0017 0.0146
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0039 0.0024
Leishmania major DNA polymerase kappa, putative 0.0022 0.0064 0.1361
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0064 0.0118
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0392 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0061 0.0308 0.5
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0201
Loa Loa (eye worm) hypothetical protein 0.0022 0.0064 0.0162
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0061 0.0308 0.2112
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0009 0.0017
Loa Loa (eye worm) latrophilin receptor protein 2 0.0037 0.0158 0.0475
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0015 0.0091
Loa Loa (eye worm) hypothetical protein 0.0045 0.0205 0.0633
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0016 0.0022 0.0221
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0015 0.0091
Leishmania major pyruvate kinase 0.0037 0.0159 0.3865
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0243 0.2358
Schistosoma mansoni cpg binding protein 0.0088 0.0483 0.0898
Plasmodium falciparum pyruvate kinase 0.0037 0.0159 0.5157
Echinococcus granulosus pyruvate kinase 0.0019 0.0043 0.0052
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0016 0.0022 0.0257
Schistosoma mansoni pyruvate kinase 0.0037 0.0159 0.0295
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0064 0.1361
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0243 0.0761
Plasmodium vivax hypothetical protein, conserved 0.0038 0.016 0.4944
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.016 0.3839
Echinococcus multilocularis pyruvate kinase 0.0029 0.0109 0.0094
Schistosoma mansoni cpg binding protein 0.0095 0.0528 0.0982
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.016 0.0891
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0243 0.7782
Trichomonas vaginalis Sentrin-specific protease, putative 0.0015 0.0017 0.0014
Echinococcus multilocularis sentrin specific protease 8 0.0015 0.0017 0.0002
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0159 0.048
Echinococcus multilocularis sentrin specific protease 1 0.0015 0.0017 0.0002
Echinococcus multilocularis microtubule associated protein 2 0.0779 0.4896 0.4889
Schistosoma mansoni tar DNA-binding protein 0.0484 0.3013 0.5602
Loa Loa (eye worm) hypothetical protein 0.0038 0.016 0.0483
Loa Loa (eye worm) TAR-binding protein 0.0484 0.3013 1
Echinococcus granulosus expressed conserved protein 0.0159 0.0934 0.1713
Loa Loa (eye worm) hypothetical protein 0.0038 0.016 0.0483
Echinococcus multilocularis 0.0016 0.0022 0.0006
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0159 0.0885
Onchocerca volvulus 0.0015 0.0017 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0064 0.1285
Echinococcus multilocularis pyruvate kinase 0.0019 0.0043 0.0028
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0294 0.0932
Brugia malayi Cytochrome P450 family protein 0.0016 0.0022 0.0022
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0039 0.0045
Schistosoma mansoni cpg binding protein 0.0095 0.0528 0.0982
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0015 0.0017 0.0168
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.0392 0.3807
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.016 0.0891
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0159 0.048
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0064 0.1361
Echinococcus multilocularis expressed conserved protein 0.0159 0.0934 0.092
Echinococcus granulosus cytochrome P450 2K1 0.0016 0.0022 0.0012
Brugia malayi RNA recognition motif domain containing protein 0.0484 0.3013 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.016 0.109
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0068 0.0099
Schistosoma mansoni hypothetical protein 0.0023 0.0064 0.012
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0064 0.1285
Loa Loa (eye worm) hypothetical protein 0.0038 0.016 0.0483
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.0043 0.0278
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0159 0.0885
Loa Loa (eye worm) hypothetical protein 0.0117 0.067 0.2185
Schistosoma mansoni pyruvate kinase 0.0019 0.0043 0.008
Schistosoma mansoni cytochrome P450 0.0016 0.0022 0.004
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0061 0.0308 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0148 0.0275
Onchocerca volvulus 0.0038 0.016 0.0891
Schistosoma mansoni hypothetical protein 0.0199 0.1194 0.2221
Brugia malayi Cytochrome P450 family protein 0.0016 0.0022 0.0022
Plasmodium falciparum pyruvate kinase 2 0.0019 0.0043 0.1388
Brugia malayi Latrophilin receptor protein 2 0.0037 0.0158 0.0475
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0054 0.0267 0.0252
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0064 0.1285
Mycobacterium leprae Probable lipase LipE 0.0038 0.016 0.6353
Echinococcus granulosus pyruvate kinase 0.0019 0.0043 0.0052
Mycobacterium leprae conserved hypothetical protein 0.0038 0.016 0.6353
Echinococcus multilocularis sentrin specific protease 7 0.0174 0.1031 0.1017
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0148 0.0275
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0048 0.0201
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0113 0.0328
Loa Loa (eye worm) histone methyltransferase 0.0028 0.0102 0.0291
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0015 0.0017 0.0007
Loa Loa (eye worm) hypothetical protein 0.0038 0.0162 0.0488

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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