Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | poly (ADP-ribose) polymerase 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.1052 | 0.1052 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.3273 | 0.4725 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1115 | 0.161 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.154 | 0.154 |
Trypanosoma brucei | poly(adp-ribose) polymerase | 0.0095 | 0.2528 | 0.2794 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0293 | 0.303 |
Onchocerca volvulus | 0.0035 | 0.0642 | 0.5889 | |
Brugia malayi | hypothetical protein | 0.0016 | 0.0042 | 0.006 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.154 | 0.2223 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0096 | 0.2551 | 0.2551 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0313 | 0.0346 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0642 | 0.141 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2528 | 0.3649 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0642 | 0.0709 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.1441 | 0.208 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.018 | 0.5185 | 1 |
Leishmania major | DNA repair protein, putative | 0.0023 | 0.0256 | 0.0282 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0464 | 0.0464 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0464 | 0.0464 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0464 | 0.0896 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0043 | 0.0063 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0304 | 0.9048 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0096 | 0.2551 | 0.3683 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0966 | 0.1395 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2376 | 0.2376 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0313 | 0.0604 |
Brugia malayi | WGR domain containing protein | 0.0174 | 0.4972 | 0.7179 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.154 | 0.154 |
Brugia malayi | CHE-14 protein | 0.0045 | 0.0966 | 0.1395 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0043 | 0.0043 |
Echinococcus granulosus | poly ADP ribose polymerase 1 | 0.0174 | 0.4972 | 0.4972 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0224 | 0.6539 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.1089 | 0.2393 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.3273 | 0.4725 |
Loa Loa (eye worm) | hypothetical protein | 0.0236 | 0.6926 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.1115 | 0.161 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0293 | 0.0423 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0313 | 0.0452 |
Leishmania major | hypothetical protein, conserved | 0.0023 | 0.0256 | 0.0282 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0131 | 0.1877 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0151 | 0.4273 | 0.4273 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0096 | 0.2551 | 0.2551 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.154 | 0.154 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0027 | 0.039 | 0.039 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0144 | 0.4043 | 0.4469 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.07 | 0.101 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0642 | 0.0981 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.3273 | 0.4725 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1119 | 0.1616 |
Onchocerca volvulus | 0.0035 | 0.0642 | 0.5889 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0642 | 0.0926 |
Onchocerca volvulus | 0.0049 | 0.1089 | 1 | |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0131 | 0.0145 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0049 | 0.1089 | 0.2393 |
Brugia malayi | RNA binding protein | 0.0064 | 0.154 | 0.2223 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0313 | 0.448 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0823 | 0.0823 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0642 | 0.0981 |
Mycobacterium ulcerans | hypothetical protein | 0.016 | 0.4551 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0236 | 0.6926 | 0.6926 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0202 | 0.2891 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0304 | 0.9048 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0642 | 0.0981 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0642 | 0.5889 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0131 | 0.1877 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0049 | 0.1089 | 0.2393 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0052 | 0.1175 | 0.1299 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0054 | 0.1232 | 0.1232 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0131 | 0.0289 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.1089 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0642 | 0.0642 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0131 | 0.0131 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0657 | 0.0657 |
Brugia malayi | hypothetical protein | 0.0236 | 0.6926 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0106 | 0.2854 | 0.2854 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0045 | 0.0966 | 0.0966 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0131 | 0.0131 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0037 | 0.07 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0642 | 0.0926 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0642 | 0.5889 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0107 | 0.2905 | 0.2905 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.07 | 0.101 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0642 | 0.6639 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0915 | 0.0915 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0043 | 0.0043 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.1115 | 0.161 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.154 | 0.154 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1089 | 0.1573 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0637 | 0.0974 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0642 | 0.0709 |
Echinococcus granulosus | peregrin | 0.0029 | 0.0464 | 0.0464 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0095 | 0.2528 | 0.2794 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0915 | 0.0915 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0637 | 0.0974 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 1 | 1 |
Echinococcus multilocularis | protein dispatched 1 | 0.0052 | 0.1167 | 0.1167 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0642 | 0.0926 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1286 | 0.1856 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.1089 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0131 | 0.019 |
Echinococcus multilocularis | poly (adp ribose) polymerase 2 | 0.0095 | 0.2528 | 0.2528 |
Echinococcus multilocularis | poly (ADP ribose) polymerase 1 | 0.0174 | 0.4972 | 0.4972 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0131 | 0.0145 |
Trypanosoma brucei | DNA repair protein, putative | 0.0023 | 0.0256 | 0.0282 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0174 | 0.4972 | 0.4972 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0642 | 0.6639 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0131 | 0.0145 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.1115 | 0.161 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0131 | 0.0145 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0642 | 0.141 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.1089 | 0.2191 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.1089 | 0.2191 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0043 | 0.0043 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0049 | 0.1089 | 0.1666 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1089 | 0.1573 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.1089 | 0.2393 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0045 | 0.0088 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0464 | 0.0464 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0043 | 0.0063 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0642 | 0.0981 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0642 | 0.1237 |
Echinococcus granulosus | expressed conserved protein | 0.0099 | 0.2654 | 0.2654 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0915 | 0.0915 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0236 | 0.6926 | 0.6926 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.2376 | 0.2376 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0043 | 0.0043 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0642 | 0.0981 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0037 | 0.07 | 0.107 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0043 | 0.0043 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0037 | 0.07 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0049 | 0.1089 | 0.2393 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0642 | 0.0981 |
Trypanosoma brucei | Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative | 0.0023 | 0.0256 | 0.0282 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.1089 | 0.1204 |
Trypanosoma cruzi | DNA repair protein, putative | 0.0023 | 0.0256 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.07 | 0.101 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0095 | 0.2528 | 0.2528 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0043 | 0.0063 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0464 | 0.6638 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.2376 | 0.2376 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.016 | 0.4551 | 0.6961 |
Echinococcus granulosus | WGR domain containing protein | 0.0054 | 0.1232 | 0.1232 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0642 | 0.0981 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0642 | 0.0709 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.154 | 0.2223 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0642 | 0.0981 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0313 | 0.0346 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0642 | 0.6639 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.33 | 0.4765 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0657 | 0.0657 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.1089 | 0.1204 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0043 | 0.0883 | 0.0976 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0313 | 0.0346 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0642 | 0.141 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0313 | 0.448 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0131 | 0.5 |
Echinococcus granulosus | poly adp ribose polymerase 2 | 0.0095 | 0.2528 | 0.2528 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0637 | 0.0974 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0642 | 0.0926 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0131 | 0.0253 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.2376 | 0.3431 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0131 | 0.0131 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0043 | 0.0043 |
Echinococcus multilocularis | expressed conserved protein | 0.0099 | 0.2654 | 0.2654 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0043 | 0.0063 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0642 | 0.141 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.2376 | 0.2376 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0657 | 0.0657 |
Onchocerca volvulus | DNA ligase 3 homolog | 0.0023 | 0.0256 | 0.2346 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0027 | 0.039 | 0.039 |
Echinococcus multilocularis | protein patched | 0.0045 | 0.0966 | 0.0966 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0045 | 0.0966 | 0.1395 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.0657 | 0.0657 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0106 | 0.2854 | 0.574 |
Schistosoma mansoni | jumonji domain containing protein | 0.0076 | 0.1934 | 0.1934 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0151 | 0.4273 | 0.4273 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0131 | 0.1359 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.154 | 0.2223 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.1052 | 0.1519 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0131 | 0.0264 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0037 | 0.07 | 0.1537 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0657 | 0.0949 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.0136 | 0.0136 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0642 | 0.0642 |
Schistosoma mansoni | patched 1 | 0.0045 | 0.0966 | 0.0966 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0966 | 1 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0016 | 0.0051 | 0.0734 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0642 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0642 | 0.0926 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0619 | 0.0619 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0464 | 0.067 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0642 | 0.0981 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0464 | 0.6638 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0131 | 0.1359 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1089 | 0.1573 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0131 | 0.0201 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0642 | 0.0981 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0915 | 0.0915 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0049 | 0.1089 | 0.2393 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0304 | 0.9048 | 1 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0304 | 0.9048 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.039 | 0.0784 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0642 | 0.6639 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0642 | 0.6639 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0131 | 0.019 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.154 | 0.154 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0293 | 0.0293 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.154 | 0.154 |
Echinococcus multilocularis | peregrin | 0.0029 | 0.0464 | 0.0464 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0256 | 0.0369 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2376 | 0.2376 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.2376 | 0.2376 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0144 | 0.4043 | 0.4469 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0642 | 0.9171 |
Mycobacterium ulcerans | hypothetical protein | 0.0049 | 0.1089 | 0.2393 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0313 | 0.448 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0293 | 0.303 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0464 | 0.0896 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0043 | 0.0043 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0642 | 0.6639 |
Entamoeba histolytica | poly(ADP-ribose) polymerase, putative | 0.0174 | 0.4972 | 1 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0082 | 0.2125 | 0.2125 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0045 | 0.0966 | 0.0966 |
Echinococcus multilocularis | poly (ADP ribose) polymerase | 0.004 | 0.0792 | 0.0792 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.1089 | 0.1204 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0642 | 0.0926 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0043 | 0.0883 | 0.0976 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0131 | 0.0131 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.2376 | 0.3431 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0642 | 0.0926 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0106 | 0.2854 | 0.4121 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.07 | 0.101 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0313 | 0.0452 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0027 | 0.039 | 0.039 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0464 | 0.067 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0144 | 0.4043 | 0.4469 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.07 | 0.101 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0642 | 0.0642 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0043 | 0.0043 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0619 | 0.0894 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0637 | 0.0974 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0313 | 0.0346 |
Loa Loa (eye worm) | poly(ADP-ribose) polymerase | 0.0068 | 0.1685 | 0.2433 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.1089 | 0.1573 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0049 | 0.1089 | 0.1666 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0464 | 0.0464 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.3677 | 0.5309 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0823 | 0.0823 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0043 | 0.0043 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0131 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.1089 | 0.2393 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0095 | 0.2528 | 0.2794 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.154 | 0.2223 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0642 | 0.0926 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.154 | 0.2223 |
Echinococcus multilocularis | geminin | 0.0334 | 1 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0642 | 0.0642 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0883 | 0.0976 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.154 | 0.154 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0106 | 0.2854 | 0.2854 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0657 | 0.0949 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0883 | 0.0976 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0293 | 0.0293 |
Brugia malayi | WGR domain containing protein | 0.0095 | 0.2528 | 0.3649 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0049 | 0.1089 | 0.2191 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0037 | 0.07 | 0.5 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0464 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0642 | 0.141 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.1089 | 0.1573 |
Brugia malayi | Bromodomain containing protein | 0.0029 | 0.0464 | 0.067 |
Onchocerca volvulus | 0.0048 | 0.1052 | 0.966 | |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0293 | 0.0423 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0642 | 0.0926 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0642 | 0.0926 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0642 | 0.0926 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0619 | 0.0894 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0464 | 0.067 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0642 | 0.0926 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0045 | 0.0966 | 0.0966 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.2854 | 0.4121 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.1089 | 0.1573 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.1052 | 0.1052 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0464 | 0.4262 |
Toxoplasma gondii | hypothetical protein | 0.0049 | 0.108 | 0.2082 |
Onchocerca volvulus | 0.0035 | 0.0642 | 0.5889 | |
Trypanosoma cruzi | Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative | 0.0023 | 0.0256 | 0.0282 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.2376 | 0.2376 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.