Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0039 | 0.0007 | 0.0007 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0113 | 0.0913 | 0.0913 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0066 | 0.0333 | 0.1153 |
Schistosoma mansoni | thyroid hormone receptor | 0.0302 | 0.3215 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.0007 | 0.0022 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0333 | 0.1036 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.0268 | 0.0931 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0066 | 0.0333 | 0.1156 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.0913 | 0.2839 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0913 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0113 | 0.0913 | 0.2839 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0007 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0143 | 0.127 | 0.3949 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0039 | 0 | 0.5 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0039 | 0.0007 | 0.0025 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.0007 | 0.5 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0039 | 0.0007 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0068 | 0.0068 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0007 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.0268 | 0.0834 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.2077 | 0.7208 |
Echinococcus multilocularis | GPCR, family 2 | 0.0066 | 0.0333 | 0.0333 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0263 | 0.2741 | 0.2741 |
Loa Loa (eye worm) | hypothetical protein | 0.0274 | 0.2881 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0274 | 0.2881 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0263 | 0.2741 | 0.8526 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.0275 | 0.2889 | 0.2889 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0068 | 0.0237 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.0007 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0113 | 0.0913 | 0.316 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0333 | 0.1036 |
Schistosoma mansoni | jumonji domain containing protein | 0.0061 | 0.0268 | 0.0834 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0913 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.0268 | 0.0931 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0061 | 0.0268 | 0.0268 |
Loa Loa (eye worm) | inositol-1 | 0.0039 | 0.0007 | 0.0025 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0209 | 0.2077 | 0.7208 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0333 | 0.1036 |
Echinococcus granulosus | GPCR family 2 | 0.0066 | 0.0333 | 0.1153 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0143 | 0.127 | 0.4407 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0007 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0068 | 0.0237 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0066 | 0.0333 | 0.1156 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0066 | 0.0333 | 0.1153 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0913 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0333 | 0.1036 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0068 | 0.0212 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0039 | 0.0007 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0068 | 0.0212 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0066 | 0.0333 | 0.0333 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0068 | 0.0236 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0913 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.0007 | 0.0022 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.0268 | 0.0834 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0039 | 0.0007 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0066 | 0.0333 | 0.1156 |
Schistosoma mansoni | thyroid hormone receptor | 0.0302 | 0.3215 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0263 | 0.2741 | 0.9488 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0061 | 0.0268 | 0.0929 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0039 | 0.0007 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0333 | 0.1156 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0268 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.127 | 0.4407 |
Brugia malayi | Inositol-1 | 0.0039 | 0.0007 | 0.0025 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0039 | 0 | 0.5 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0007 | 0.5 |
Brugia malayi | hypothetical protein | 0.0113 | 0.0913 | 0.3168 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0209 | 0.2077 | 0.7208 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0209 | 0.2077 | 0.7208 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0068 | 0.0212 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0066 | 0.0333 | 0.0333 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0068 | 0.0236 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0039 | 0 | 0.5 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0061 | 0.0268 | 0.0929 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0302 | 0.3215 | 0.3215 |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.0275 | 0.2889 | 1 |
Onchocerca volvulus | 0.0039 | 0 | 0.5 | |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0061 | 0.0268 | 0.0268 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0068 | 0.0068 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.