Detailed information for compound 1008286

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 404.897 | Formula: C16H13ClN6OS2
  • H donors: 0 H acceptors: 5 LogP: 3.67 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cccc(c1)CSc1nnc(o1)CSc1nn2c(n1)nc(cc2)C
  • InChi: 1S/C16H13ClN6OS2/c1-10-5-6-23-14(18-10)19-15(22-23)25-9-13-20-21-16(24-13)26-8-11-3-2-4-12(17)7-11/h2-7H,8-9H2,1H3
  • InChiKey: QIXXNVAZGSIOQZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0383 0.052
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0157 0.0229
Schistosoma mansoni aldehyde dehydrogenase 0.0249 0.1492 0.1473
Brugia malayi MH2 domain containing protein 0.0606 0.3862 0.5529
Brugia malayi Heterochromatin protein 1 0.0144 0.0794 0.1112
Echinococcus multilocularis ecdysone induced protein 78C 0.0072 0.0314 0.0327
Echinococcus granulosus thyroid hormone receptor alpha 0.0034 0.0061 0.0045
Entamoeba histolytica mannose-6-phosphate isomerase, putative 0.0047 0.0151 0.0332
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0157 0.0152
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0551 0.1419
Brugia malayi Importin beta-1 subunit 0.0029 0.0025 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0573 0.3643 0.4563
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0044 0.0128 0.012
Echinococcus granulosus jumonji domain containing protein 0.0082 0.0383 0.0404
Giardia lamblia Thioredoxin reductase 0.0044 0.0128 0.027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0938 0.2417
Plasmodium vivax heat shock protein 86, putative 0.0098 0.0484 0.1603
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0271 0.0679
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0938 0.2417
Brugia malayi jmjC domain containing protein 0.0084 0.039 0.0531
Entamoeba histolytica hypothetical protein 0.0036 0.0075 0.0127
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.371 0.4647
Loa Loa (eye worm) programmed cell death 8 0.0044 0.0128 0.0157
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.0061 0.0049
Brugia malayi beta-lactamase family protein 0.0036 0.0075 0.0077
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0075 0.0029
Echinococcus multilocularis polycomb protein SCMH1 0.0147 0.0811 0.0881
Echinococcus granulosus lamin 0.0028 0.0022 0.0002
Schistosoma mansoni sex comb on midleg homolog 0.0147 0.0811 0.0791
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0044 0.0128 0.0342
Brugia malayi Nuclear hormone receptor-like 1 0.0072 0.0314 0.0421
Loa Loa (eye worm) hypothetical protein 0.0034 0.0062 0.0063
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0551 0.0766
Brugia malayi Endoplasmin precursor 0.0098 0.0484 0.0665
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0157 0.0152
Plasmodium falciparum endoplasmin, putative 0.006 0.0233 0.0772
Onchocerca volvulus 0.1221 0.7951 1
Mycobacterium ulcerans monoxygenase 0.0044 0.0128 0.0317
Echinococcus multilocularis chromobox protein 1 0.0144 0.0794 0.0862
Giardia lamblia Kinase, PLK 0.0573 0.3643 0.9819
Loa Loa (eye worm) hypothetical protein 0.0166 0.0939 0.1324
Schistosoma mansoni zinc finger protein 0.0034 0.0061 0.0039
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0075 0.0029
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0166 0.0938 1
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0044 0.0128 0.0317
Brugia malayi Doublecortin family protein 0.0061 0.0238 0.0311
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0061 0.0045
Entamoeba histolytica 90 kDa heat shock protein, putative 0.004 0.0101 0.0196
Schistosoma mansoni serine/threonine protein kinase 0.0573 0.3643 0.3629
Trypanosoma cruzi heat shock protein 90, putative 0.0098 0.0484 0.1144
Brugia malayi isocitrate dehydrogenase 0.0048 0.0157 0.0194
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Trypanosoma cruzi NADH dehydrogenase, putative 0.0044 0.0128 0.0147
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0044 0.0128 0.0157
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0157 0.0152
Schistosoma mansoni sulfide quinone reductase 0.0044 0.0128 0.0106
Plasmodium falciparum ferrodoxin reductase-like protein 0.0044 0.0128 0.0423
Trichomonas vaginalis apoptosis inducing factor, putative 0.0044 0.0128 0.0125
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0082 0.0069
Entamoeba histolytica heat shock protein 90, putative 0.0098 0.0484 0.1236
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0081 0.0372 0.0442
Trichomonas vaginalis CAMK family protein kinase 0.0573 0.3643 0.4563
Brugia malayi MH1 domain containing protein 0.0041 0.0109 0.0126
Trypanosoma cruzi heat shock protein, putative 0.004 0.0101 0.0071
Trypanosoma brucei heat shock protein, putative 0.0098 0.0484 0.1266
Leishmania major heat shock protein, putative 0.004 0.0101 0.0071
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0044 0.0128 0.012
Loa Loa (eye worm) pax transcription factor protein 2 0.0251 0.1501 0.2134
Trichomonas vaginalis mannose-6-phosphate isomerase, putative 0.0104 0.0524 0.0626
Brugia malayi Nuclear hormone receptor E75 0.0034 0.0061 0.0056
Onchocerca volvulus 0.0089 0.0429 0.0514
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.0061 0.0045
Loa Loa (eye worm) nuclear receptor NHR-67 0.0034 0.0061 0.0061
Plasmodium falciparum JmjC domain-containing protein, putative 0.0084 0.039 0.1294
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0044 0.0128 0.027
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0064 0.0045
Onchocerca volvulus 0.0082 0.0383 0.0455
Treponema pallidum heat shock protein 90 0.0078 0.0351 0.0877
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0551 0.0766
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.0061 0.0045
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0044 0.0128 0.0575
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0413 0.0486
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0075 0.0061
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0022 0.0005
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0044 0.0128 0.0423
Plasmodium falciparum glutathione reductase 0.0166 0.0938 0.3108
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0166 0.0938 0.5218
Onchocerca volvulus 0.0072 0.0314 0.0368
Loa Loa (eye worm) hypothetical protein 0.0038 0.0088 0.01
Trichomonas vaginalis glutamate synthase, putative 0.0044 0.0128 0.0125
Onchocerca volvulus 0.0044 0.0128 0.0134
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0044 0.0128 0.0095
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0938 0.2417
Brugia malayi MH2 domain containing protein 0.0041 0.0109 0.0126
Schistosoma mansoni heat shock protein 0.004 0.0101 0.0079
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0413 0.0486
Plasmodium vivax endoplasmin, putative 0.0098 0.0484 0.1603
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.0061 0.0049
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0157 0.0363
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.137 0.1677
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0028 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0072 0.0314 0.0425
Leishmania major hypothetical protein, conserved 0.0044 0.0128 0.0147
Trichomonas vaginalis CAMK family protein kinase 0.0573 0.3643 0.4563
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0551 0.066
Loa Loa (eye worm) inositol-1 0.0037 0.0078 0.0086
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0082 0.0018
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0551 0.1333
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Echinococcus granulosus histone acetyltransferase MYST2 0.0167 0.0946 0.1032
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0082
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0078 0.0351 0.0774
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0258 0.0236
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0044 0.0128 0.0125
Entamoeba histolytica hypothetical protein 0.0036 0.0075 0.0127
Loa Loa (eye worm) DR-78 0.0034 0.0061 0.0061
Schistosoma mansoni nuclear receptor 0.0034 0.0061 0.0039
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0551 0.2878
Onchocerca volvulus Serine\/threonine kinase homolog 0.0573 0.3643 0.4567
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0075 0.0053
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0044 0.0128 0.0125
Brugia malayi mbt repeat family protein 0.0147 0.0811 0.1137
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0157 0.052
Loa Loa (eye worm) doublecortin family protein 0.0061 0.0238 0.0316
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0122 0.0645 0.0897
Giardia lamblia NADH oxidase lateral transfer candidate 0.0166 0.0938 0.247
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0072 0.0314 0.0421
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0078 0.0063
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0078 0.0063
Toxoplasma gondii phosphomannose isomerase type I protein 0.0104 0.0524 0.1668
Loa Loa (eye worm) transcription factor SMAD2 0.0606 0.3862 0.5531
Plasmodium falciparum LCCL domain-containing protein 0.0061 0.0238 0.0789
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0551 0.1419
Loa Loa (eye worm) hypothetical protein 0.0084 0.039 0.0535
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0078 0.0351 0.3178
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0551 0.0635
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0075 0.0029
Giardia lamblia Heat shock protein HSP 90-alpha 0.0098 0.0484 0.1236
Entamoeba histolytica heat shock protein 90, putative 0.0098 0.0484 0.1236
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0938 0.2417
Leishmania major hypothetical protein, conserved 0.0084 0.039 0.0883
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0044 0.0128 0.0153
Mycobacterium tuberculosis Probable reductase 0.1092 0.7094 0.8968
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0166 0.0938 0.2417
Echinococcus granulosus ecdysone induced protein 78C 0.0072 0.0314 0.0327
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0249 0.1492 0.164
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0258 0.0236
Brugia malayi Steroid receptor seven-up type 2 0.0072 0.0314 0.0421
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0044 0.0128 0.0317
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0044 0.0128 0.0095
Trichomonas vaginalis heat shock protein, putative 0.0098 0.0484 0.0574
Mycobacterium ulcerans NADH dehydrogenase 0.0044 0.0128 0.0317
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0082 0.0067
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0064 0.0045
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0044 0.0128 0.012
Echinococcus multilocularis phd:f box containing protein 0.0084 0.039 0.0412
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.371 0.4647
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0271 0.0279
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0127 0.0124
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0551 0.1452
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0104 0.0524 0.0724
Brugia malayi SET domain containing protein 0.0031 0.0043 0.003
Entamoeba histolytica serine/threonine protein kinase, putative 0.0573 0.3643 0.9819
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0075 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0551 0.066
Brugia malayi RNA, U transporter 1 0.0081 0.0377 0.0511
Trichomonas vaginalis CAMK family protein kinase 0.0284 0.172 0.2135
Brugia malayi jmjC domain containing protein 0.0436 0.2731 0.39
Onchocerca volvulus 0.0034 0.0061 0.0049
Giardia lamblia Glutamate synthase 0.0044 0.0128 0.027
Trypanosoma brucei polo-like protein kinase 0.0573 0.3643 1
Schistosoma mansoni endoplasmin 0.0098 0.0484 0.0463
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Brugia malayi Inositol-1 0.0037 0.0078 0.0081
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0089 0.0424 0.045
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0258 0.0236
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0059 0.0229 0.0208
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0166 0.0938 0.2417
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0166 0.0938 0.3108
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0084 0.039 0.122
Schistosoma mansoni kinase 0.0291 0.1771 0.1753
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0044 0.0128 0.027
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1214 0.7904 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0157 0.0229
Brugia malayi jmjC domain containing protein 0.0084 0.039 0.0531
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0166 0.0938 0.2521
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0075 0.0059
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0078 0.0065
Schistosoma mansoni cpg binding protein 0.0094 0.0463 0.0442
Loa Loa (eye worm) hypothetical protein 0.0147 0.0811 0.1141
Loa Loa (eye worm) hypothetical protein 0.0072 0.0314 0.0425
Brugia malayi jmjC domain containing protein 0.0084 0.039 0.0531
Onchocerca volvulus 0.0251 0.1501 0.1866
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0166 0.0938 0.2521
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0044 0.0128 0.0342
Entamoeba histolytica hypothetical protein 0.0036 0.0075 0.0127
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0044 0.0128 0.012
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0082 0.0069
Trichomonas vaginalis heat shock protein, putative 0.0078 0.0351 0.0408
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0044 0.0128 0.012
Brugia malayi chromobox protein homolog 3 0.0081 0.0372 0.0505
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0034 0.0061 0.0056
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0104 0.0524 0.0724
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0072 0.0314 0.0421
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0044 0.0128 0.0125
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0029 0.0026 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0072 0.0314 0.0425
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0573 0.3643 0.4036
Echinococcus multilocularis musashi 0.0028 0.0022 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0072 0.0314 0.0421
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0082
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0229 0.068
Echinococcus granulosus tar DNA binding protein 0.0064 0.0258 0.0265
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0168 0.021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.371 0.4647
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0044 0.0128 0.0317
Echinococcus multilocularis glutamate synthase 0.0044 0.0128 0.012
Schistosoma mansoni chromobox protein 0.0144 0.0794 0.0774
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0072 0.0314 0.0327
Trichomonas vaginalis heat shock protein, putative 0.004 0.0101 0.0091
Echinococcus granulosus importin subunit beta 1 0.0029 0.0025 0.0006
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0028 0.001
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0551 0.1419
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0082 0.0145
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0072 0.0314 0.0327
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0082 0.0086
Trichomonas vaginalis chromobox protein, putative 0.0144 0.0794 0.0966
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0075 0.0061
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0551 0.066
Treponema pallidum NADH oxidase 0.0166 0.0938 0.247
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Schistosoma mansoni cpg binding protein 0.0089 0.0429 0.0408
Brugia malayi photoreceptor-specific nuclear receptor 0.0072 0.0314 0.0421
Brugia malayi CXXC zinc finger family protein 0.0089 0.0429 0.0586
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0044 0.0128 0.0317
Trypanosoma brucei heat shock protein, putative 0.0098 0.0484 0.1266
Schistosoma mansoni nuclear hormone receptor 0.0072 0.0314 0.0293
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0271 0.025
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0044 0.0128 0.012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0082 0.0091
Echinococcus granulosus jumonji domain containing 1A 0.0084 0.039 0.0412
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0249 0.1492 0.3971
Echinococcus granulosus snurportin 1 0.0306 0.1868 0.2059
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0029 0.0026 0.0004
Loa Loa (eye worm) histone methyltransferase 0.0033 0.0056 0.0055
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0075 0.0029
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0088 0.0095
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0166 0.0938 0.2521
Schistosoma mansoni heat shock protein 0.0098 0.0484 0.0463
Echinococcus multilocularis heat shock protein 90 0.0098 0.0484 0.0516
Schistosoma mansoni phd/f-box containing protein 0.0084 0.039 0.0369
Echinococcus multilocularis geminin 0.0338 0.2085 0.23
Echinococcus multilocularis jumonji domain containing 1A 0.0084 0.039 0.0412
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0249 0.1492 0.164
Echinococcus multilocularis mannose 6 phosphate isomerase 0.0104 0.0524 0.0562
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.371 0.4647
Giardia lamblia Fructose-bisphosphate aldolase 0.0583 0.371 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0167 0.0946 0.1032
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0166 0.0938 0.3049
Chlamydia trachomatis thioredoxin reductase 0.0044 0.0128 0.1092
Treponema pallidum oxidoreductase 0.0044 0.0128 0.027
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0167 0.0946 0.1331
Loa Loa (eye worm) hypothetical protein 0.0084 0.039 0.0535
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.371 0.4647
Loa Loa (eye worm) hypothetical protein 0.0028 0.0022 0.0005
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0082 0.0018
Brugia malayi heat shock protein 90 0.0098 0.0484 0.0665
Trypanosoma brucei Heat shock protein 83, putative 0.0098 0.0484 0.1266
Loa Loa (eye worm) hypothetical protein 0.0156 0.0869 0.1224
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0938 0.2417
Brugia malayi CHD4 protein 0.0029 0.0026 0.0006
Echinococcus multilocularis SAM and MBT domain containing protein 0.0147 0.0811 0.0881
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0166 0.0938 0.0918
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0156 0.0869 0.0849
Plasmodium vivax heat shock protein 90, putative 0.004 0.0101 0.0334
Loa Loa (eye worm) thioredoxin reductase 0.0479 0.3017 0.4315
Echinococcus granulosus endoplasmin 0.0078 0.0351 0.0369
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0072 0.0314 0.0327
Echinococcus multilocularis Smad4 0.0041 0.0109 0.0099
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0271 0.0364
Echinococcus granulosus SAM and MBT domain containing protein 0.0147 0.0811 0.0881
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0072 0.0314 0.0293
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0089 0.0424 0.045
Echinococcus granulosus RUN 0.0061 0.0238 0.0243
Schistosoma mansoni inositol monophosphatase 0.0037 0.0078 0.0057
Echinococcus granulosus histone lysine methyltransferase setb 0.0156 0.0869 0.0946
Giardia lamblia PHD finger protein 15 0.0059 0.0229 0.0544
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0072 0.0314 0.0327
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0075 0.0077
Echinococcus multilocularis thyroid hormone receptor alpha 0.0072 0.0314 0.0327
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0075 0.0054
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0484 0.1144
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0038 0.0088 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0082 0.0067
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0128 0.0125
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Plasmodium falciparum glutathione reductase 0.0479 0.3017 1
Trichomonas vaginalis endoplasmin, putative 0.006 0.0233 0.0258
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Echinococcus granulosus Smad4 0.0041 0.0109 0.0099
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0168 0.021
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0044 0.0128 0.0153
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0044 0.0128 0.0317
Trichomonas vaginalis chromobox protein, putative 0.0144 0.0794 0.0966
Onchocerca volvulus 0.0885 0.5716 0.7181
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.0314 0.0327
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0044 0.0128 0.0147
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0258 0.0344
Schistosoma mansoni retinoic acid receptor RXR 0.0072 0.0314 0.0293
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0072 0.0314 0.0425
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0044 0.0128 0.012
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0166 0.0938 1
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0157 0.0439
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0038 0.0088 0.0076
Echinococcus granulosus smad 0.0041 0.0109 0.0099
Echinococcus granulosus Polycystic kidney disease protein 0.0061 0.0238 0.0243
Trypanosoma brucei heat shock protein 90, putative 0.0098 0.0484 0.1266
Schistosoma mansoni hypothetical protein 0.0036 0.0075 0.0053
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0551 0.053
Loa Loa (eye worm) hypothetical protein 0.0038 0.0088 0.01
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.0061 0.0045
Onchocerca volvulus Bile acid receptor homolog 0.0072 0.0314 0.0368
Onchocerca volvulus 0.0034 0.0061 0.0049
Schistosoma mansoni nuclear receptor 0.0034 0.0061 0.0039
Onchocerca volvulus 0.0061 0.0238 0.0273
Trichomonas vaginalis mercuric reductase, putative 0.0166 0.0938 0.1148
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0271 0.0359
Mycobacterium ulcerans aldehyde dehydrogenase 0.0249 0.1492 0.8572
Mycobacterium ulcerans hypothetical protein 0.0044 0.0128 0.0317
Loa Loa (eye worm) Smad1 0.0041 0.0109 0.0131
Schistosoma mansoni hypothetical protein 0.0893 0.5769 0.576
Echinococcus multilocularis endoplasmin 0.0078 0.0351 0.0369
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0127 0.0124
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0078 0.0009
Loa Loa (eye worm) heat shock protein 90 0.0098 0.0484 0.0669
Brugia malayi beta-lactamase family protein 0.0036 0.0075 0.0077
Loa Loa (eye worm) hypothetical protein 0.005 0.0168 0.0215
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0072 0.0314 0.0421
Loa Loa (eye worm) hypothetical protein 0.0885 0.5716 0.8199
Echinococcus multilocularis RUN 0.0061 0.0238 0.0243
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0062 0.0059
Echinococcus multilocularis lipoxygenase domain containing protein 0.0061 0.0238 0.0243
Trichomonas vaginalis CAMK family protein kinase 0.0573 0.3643 0.4563
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0044 0.0128 0.012
Trichomonas vaginalis heat shock protein, putative 0.006 0.0233 0.0258
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0258 0.0236
Loa Loa (eye worm) jmjC domain-containing protein 0.0084 0.039 0.0535
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0044 0.0128 0.0095
Toxoplasma gondii ABC1 family protein 0.0036 0.0075 0.0166
Treponema pallidum thioredoxin reductase (trxB) 0.0044 0.0128 0.027
Mycobacterium ulcerans ferredoxin reductase 0.0044 0.0128 0.0317
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0082 0.0069
Loa Loa (eye worm) hypothetical protein 0.0044 0.0128 0.0157
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0147 0.0811 0.0996
Schistosoma mansoni mannose-6-phosphate isomerase 0.0104 0.0524 0.0504
Giardia lamblia Heat shock protein HSP 90-alpha 0.0078 0.0351 0.0877
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0082
Schistosoma mansoni hypothetical protein 0.0034 0.0062 0.0041
Brugia malayi ecdysone receptor 0.0034 0.0061 0.0056
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0166 0.0938 0.1319
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0157 0.0229
Loa Loa (eye worm) hypothetical protein 0.0059 0.0229 0.0303
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0029 0.0026 0.0006
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0072 0.0314 0.0425
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0166 0.0938 0.2417
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0127 0.0124
Plasmodium vivax ferrodoxin reductase, putative 0.0044 0.0128 0.0423
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0484 0.1144
Echinococcus multilocularis jumonji domain containing protein 0.0082 0.0383 0.0404
Echinococcus multilocularis PHD finger protein rhinoceros 0.0059 0.0229 0.0233
Brugia malayi PHD-finger family protein 0.0059 0.0229 0.0298
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0166 0.0938 0.3108
Echinococcus granulosus TGF beta signal transducer SmadC 0.0041 0.0109 0.0099
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0044 0.0128 0.0575
Brugia malayi jmjC domain containing protein 0.0084 0.039 0.0531
Brugia malayi nuclear receptor NHR-88 0.0034 0.0061 0.0056
Brugia malayi orphan nuclear receptor NR2E1 0.0034 0.0061 0.0056
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0038 0.0088 0.0066
Mycobacterium ulcerans glutamate synthase subunit beta 0.0044 0.0128 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0372 0.0434
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0573 0.3643 1
Schistosoma mansoni lipoxygenase 0.0061 0.0238 0.0217
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0072 0.0314 0.0327
Loa Loa (eye worm) hypothetical protein 0.0038 0.0088 0.01
Entamoeba histolytica phosphomannose isomerase, putative 0.0104 0.0524 0.1347
Echinococcus granulosus mothers against decapentaplegic 5 0.0041 0.0109 0.0099
Mycobacterium tuberculosis Probable oxidoreductase 0.1214 0.7904 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0041 0.0109 0.0131
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.0061 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0072 0.0314 0.0425
Echinococcus multilocularis thioredoxin glutathione reductase 0.0481 0.3034 0.3358
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0044 0.0128 0.0095
Brugia malayi Bromodomain containing protein 0.0059 0.0229 0.0298
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO 0.0056 0.0209 0.0199
Trichomonas vaginalis heat shock protein, putative 0.0078 0.0351 0.0408
Trichomonas vaginalis set domain proteins, putative 0.1221 0.7951 1
Mycobacterium ulcerans dehydrogenase 0.0044 0.0128 0.0317
Schistosoma mansoni Smad4 0.0041 0.0109 0.0088
Echinococcus multilocularis mothers against decapentaplegic 5 0.0041 0.0109 0.0099
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0271 0.0549
Trichomonas vaginalis CAMK family protein kinase 0.0573 0.3643 0.4563
Toxoplasma gondii heat shock protein 75, putative 0.004 0.0101 0.0252
Trypanosoma brucei heat shock protein, putative 0.0098 0.0484 0.1266
Brugia malayi hypothetical protein 0.0038 0.0088 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0072 0.0314 0.0421
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0583 0.371 1
Brugia malayi hypothetical protein 0.0034 0.0061 0.0056
Echinococcus multilocularis peregrin 0.0059 0.0229 0.0233
Entamoeba histolytica thioredoxin reductase, putative 0.0044 0.0128 0.027
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0044 0.0128 0.0423
Schistosoma mansoni polycystin 1-related 0.0061 0.0238 0.0217
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0087 0.0075
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0054 0.0033
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0044 0.0128 0.027
Plasmodium falciparum thioredoxin reductase 0.0166 0.0938 0.3108
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0156 0.0869 0.0946
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.004 0.0101 0.009
Schistosoma mansoni thyroid hormone receptor 0.0072 0.0314 0.0293
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0258 0.034
Plasmodium vivax SET domain protein, putative 0.0156 0.0869 0.2881
Trypanosoma brucei heat shock protein 90, putative 0.0098 0.0484 0.1266
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0075 0.0082
Schistosoma mansoni disulfide oxidoreductase 0.0044 0.0128 0.0106
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0166 0.0938 0.3108
Echinococcus granulosus FTZ F1 alpha 0.0072 0.0314 0.0327
Toxoplasma gondii selenide, water dikinase 0.0044 0.0128 0.0342
Loa Loa (eye worm) RNA binding protein 0.0064 0.0258 0.0344
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0583 0.371 1
Mycobacterium ulcerans heat shock protein 90 0.0078 0.0351 0.1671
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0166 0.0938 0.1022
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0579 0.3682 0.4079
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA 0.0104 0.0524 0.2717
Loa Loa (eye worm) hypothetical protein 0.0061 0.0238 0.0316
Echinococcus multilocularis nuclear receptor nhr 48 0.0034 0.0061 0.0045
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0072 0.0314 0.0293
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0078 0.0065
Echinococcus multilocularis heat shock protein 0.0098 0.0484 0.0516
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0084 0.039 0.0883
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0044 0.0128 0.0095
Plasmodium vivax multidomain scavenger receptor, putative 0.0061 0.0238 0.0789
Toxoplasma gondii aldehyde dehydrogenase 0.0249 0.1492 0.4902
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0028 0.001
Loa Loa (eye worm) hypothetical protein 0.0072 0.0314 0.0425
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0082
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0044 0.0127 0.0124
Trypanosoma cruzi phosphomannose isomerase, putative 0.0104 0.0524 0.1259
Echinococcus granulosus JmjC domain containing protein 4 0.0084 0.039 0.0412
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Schistosoma mansoni sulfide quinone reductase 0.0044 0.0128 0.0106
Loa Loa (eye worm) hypothetical protein 0.0072 0.0314 0.0425
Trypanosoma brucei phosphomannose isomerase 0.0104 0.0524 0.1379
Schistosoma mansoni jumonji/arid domain-containing protein 0.0318 0.1951 0.1934
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0061 0.0039
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0044 0.0128 0.0342
Schistosoma mansoni endoplasmin 0.0098 0.0484 0.0463
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0038 0.0088 0.0076
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0084 0.039 0.1009
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0041 0.0109 0.0088
Brugia malayi nuclear receptor RXR 0.0038 0.0088 0.0095
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0028 0.001
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0157 0.0363
Schistosoma mansoni smad1 5 8 and 0.0041 0.0109 0.0088
Echinococcus granulosus heat shock protein 90 0.0098 0.0484 0.0516
Trypanosoma cruzi heat shock protein 90, putative 0.0058 0.0218 0.0399
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0127 0.0124
Loa Loa (eye worm) hypothetical protein 0.0082 0.0383 0.0524
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0034 0.0061 0.0061
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0072 0.0314 0.0368
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0084 0.039 0.0369
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0122 0.0645 0.0897
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0157 0.052
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1073 0.6967 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.1092 0.7094 0.8968
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0044 0.0128 0.0342
Trichomonas vaginalis glutathione reductase, putative 0.0166 0.0938 0.1148
Echinococcus multilocularis FTZ F1 alpha 0.0072 0.0314 0.0327
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.004 0.0101 0.01
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.1092 0.7094 0.8968
Trypanosoma cruzi trypanothione reductase, putative 0.0166 0.0938 0.2417
Loa Loa (eye worm) hypothetical protein 0.0038 0.0088 0.01
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0128 0.0125
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0573 0.3643 0.5217
Plasmodium falciparum importin beta, putative 0.0029 0.0025 0.0084
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0044 0.0128 0.0283
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0072 0.0314 0.0327
Plasmodium falciparum thioredoxin reductase 0.0479 0.3017 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0166 0.0938 0.5218
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0044 0.0128 0.0317
Echinococcus multilocularis lamin 0.0028 0.0022 0.0002
Schistosoma mansoni importin beta-1 0.0029 0.0025 0.0004
Trypanosoma cruzi phosphomannose isomerase, putative 0.0104 0.0524 0.1259
Schistosoma mansoni aldehyde dehydrogenase 0.0249 0.1492 0.1473
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0033 0.0056 0.004
Loa Loa (eye worm) steroid hormone receptor 0.0072 0.0314 0.0425
Trypanosoma cruzi NADH dehydrogenase, putative 0.0044 0.0128 0.0147
Onchocerca volvulus 0.0036 0.0075 0.0067
Echinococcus multilocularis lipoxygenase domain containing protein 0.0061 0.0238 0.0243
Schistosoma mansoni glutamate synthase 0.0044 0.0128 0.0106
Echinococcus granulosus PHD finger protein rhinoceros 0.0059 0.0229 0.0233
Trypanosoma brucei trypanothione reductase 0.0479 0.3017 0.8269
Loa Loa (eye worm) PHD-finger family protein 0.0059 0.0229 0.0303
Echinococcus multilocularis lysine specific demethylase 5A 0.0313 0.1918 0.2114
Echinococcus multilocularis lysine specific demethylase 6a 0.0084 0.039 0.0412
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0258 0.0344
Schistosoma mansoni smad1 5 8 and 0.0041 0.0109 0.0088
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0383 0.0404
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Onchocerca volvulus 0.0179 0.1026 0.1267
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0166 0.0938 0.1127
Brugia malayi hypothetical protein 0.0038 0.0088 0.0095
Echinococcus multilocularis chromobox protein 1 0.0144 0.0794 0.0862
Plasmodium falciparum phd finger protein, putative 0.0059 0.0229 0.0759
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0157 0.0132
Echinococcus granulosus thioredoxin glutathione reductase 0.0481 0.3034 0.3358
Loa Loa (eye worm) runx1 0.0111 0.0573 0.0798
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0025 0.0006
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0044 0.0128 0.0283
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0034 0.0061 0.0039
Schistosoma mansoni glutamate synthase 0.0044 0.0128 0.0106
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0271 0.0279
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0082 0.0018
Trypanosoma cruzi heat shock protein 85, putative 0.0078 0.0351 0.0774
Leishmania major phosphomannose isomerase 0.0104 0.0524 0.1259
Brugia malayi hypothetical protein 0.0034 0.0061 0.0056
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0579 0.3682 0.4079
Brugia malayi mbt repeat family protein 0.0147 0.0811 0.1137
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0551 0.1419
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0034 0.0061 0.0045
Leishmania major NADH dehydrogenase, putative 0.0044 0.0128 0.0147
Leishmania major hypothetical protein, conserved 0.0044 0.0128 0.0147
Brugia malayi RNA binding protein 0.0064 0.0258 0.034
Onchocerca volvulus 0.0061 0.0238 0.0273
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0078 0.0135
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0087 0.0413 0.0494
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0075 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0072 0.0314 0.0425
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0082 0.006
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0084 0.039 0.122
Schistosoma mansoni lipoxygenase 0.017 0.0963 0.0943
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0047 0.0149 0.0127
Brugia malayi MH1 domain containing protein 0.0041 0.0109 0.0126
Treponema pallidum fructose-bisphosphate aldolase 0.0583 0.371 1
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0372 0.0434
Schistosoma mansoni rab6-interacting 0.0061 0.0238 0.0217
Plasmodium vivax JmjC domain containing protein 0.0084 0.039 0.1294
Echinococcus granulosus cpg binding protein 0.0094 0.0463 0.0493
Brugia malayi nuclear receptor NHR-88 0.0072 0.0314 0.0421
Plasmodium falciparum heat shock protein 90, putative 0.004 0.0101 0.0334
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.0314 0.0327
Leishmania major hypothetical protein, conserved 0.0044 0.0128 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0072 0.0314 0.0421
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0168 0.0215
Echinococcus granulosus heat shock protein 90 0.0078 0.0351 0.0369
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0271 0.0659
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0216 0.0236
Echinococcus multilocularis snurportin 1 0.0306 0.1868 0.2059
Loa Loa (eye worm) jmjC domain-containing protein 0.0122 0.0648 0.0907
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.001
Onchocerca volvulus 0.0063 0.0256 0.0296
Schistosoma mansoni microtubule-associated protein tau 0.1378 0.8997 0.8995
Schistosoma mansoni hypothetical protein 0.0044 0.0128 0.0106
Echinococcus granulosus glutamate synthase 0.0044 0.0128 0.012
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0075 0.0059
Mycobacterium tuberculosis Conserved protein 0.0036 0.0075 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0573 0.3643 0.4563
Loa Loa (eye worm) glutathione reductase 0.0479 0.3017 0.4315
Trichomonas vaginalis heat shock protein, putative 0.0078 0.0351 0.0408
Entamoeba histolytica disulphide oxidoreductase, putative 0.0044 0.0128 0.027
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0383 0.0404
Schistosoma mansoni hypothetical protein 0.0338 0.2085 0.2068
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0078 0.0351 0.0369
Brugia malayi Pre-SET motif family protein 0.1073 0.6967 1
Loa Loa (eye worm) beta-lactamase 0.0036 0.0075 0.0082
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0087 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0072 0.0314 0.0421
Brugia malayi nuclear hormone receptor family member odr-7 0.0034 0.0061 0.0056
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0044 0.0128 0.0283
Echinococcus granulosus peregrin 0.0059 0.0229 0.0233
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0383 0.0362
Brugia malayi Nuclear hormone receptor E75 0.0034 0.0061 0.0056
Plasmodium falciparum heat shock protein 90, putative 0.004 0.0101 0.0334
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0157 0.0194
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0078 0.0009
Schistosoma mansoni cpg binding protein 0.0094 0.0463 0.0442
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0075 0.0029
Trichomonas vaginalis esterase, putative 0.0036 0.0075 0.0059
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0044 0.0128 0.0147
Brugia malayi Smad1 0.0041 0.0109 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0216 0.0236
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0072 0.0314 0.0421
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0044 0.0128 0.0095
Mycobacterium tuberculosis Conserved protein 0.0036 0.0075 0.0029
Loa Loa (eye worm) hypothetical protein 0.0072 0.0314 0.0425
Brugia malayi 6-phosphofructokinase 0.0108 0.0551 0.0762
Mycobacterium tuberculosis Conserved protein 0.0036 0.0075 0.0029
Loa Loa (eye worm) heterochromatin protein 1 0.0144 0.0794 0.1116
Brugia malayi hypothetical protein 0.0036 0.0075 0.0077
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0082
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0229 0.0759
Brugia malayi hypothetical protein 0.0885 0.5716 0.8198
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0044 0.0128 0.0342
Schistosoma mansoni smad1 5 8 and 0.0041 0.0109 0.0088
Loa Loa (eye worm) hypothetical protein 0.0167 0.0946 0.1335
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0072 0.0314 0.0421
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Brugia malayi Thioredoxin reductase 0.0479 0.3017 0.4313
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0028 0.0094
Schistosoma mansoni coup transcription factor 0.0072 0.0314 0.0293
Onchocerca volvulus 0.0036 0.0075 0.0067
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0082 0.0069
Toxoplasma gondii thioredoxin reductase 0.0479 0.3017 1
Trypanosoma cruzi heat shock protein 90, putative 0.0078 0.0351 0.0774
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0075 0.0059
Trypanosoma brucei NADH dehydrogenase 0.0044 0.0128 0.0283
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0157 0.0439
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.1092 0.7094 0.8968
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0082 0.0156
Loa Loa (eye worm) hypothetical protein 0.0072 0.0314 0.0425
Onchocerca volvulus Protein ultraspiracle homolog 0.0072 0.0314 0.0368
Schistosoma mansoni chromobox protein 0.0144 0.0794 0.0774
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0044 0.0128 0.012
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.004 0.0101 0.009
Echinococcus granulosus polycomb protein SCMH1 0.0147 0.0811 0.0881
Trypanosoma brucei heat shock protein, putative 0.0098 0.0484 0.1266
Brugia malayi nuclear receptor RXR 0.0034 0.0061 0.0056
Trypanosoma brucei heat shock protein, putative 0.0098 0.0484 0.1266
Loa Loa (eye worm) CHromoDomain protein family member 0.0029 0.0026 0.0011
Trypanosoma brucei heat shock protein 84, putative 0.004 0.0101 0.0208
Schistosoma mansoni glutamate synthase 0.0044 0.0128 0.0106
Schistosoma mansoni RAR-like nuclear receptor 0.0072 0.0314 0.0293
Echinococcus granulosus intermediate filament protein 0.0028 0.0022 0.0002
Brugia malayi conserved hypotetical protein 0.0034 0.0061 0.0056
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0551 0.0766
Brugia malayi glutamate synthase 0.0044 0.0128 0.0153
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0551 0.0591
Mycobacterium ulcerans aldehyde dehydrogenase 0.0249 0.1492 0.8572
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0044 0.0128 0.0095
Schistosoma mansoni myelin transcription factor 1 myt1 0.0167 0.0946 0.0927
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0044 0.0128 0.0147
Schistosoma mansoni jumonji/arid domain-containing protein 0.0318 0.1951 0.1934
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0088 0.0066
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0072 0.0314 0.0327
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0128 0.0125
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0195 0.1133 0.1113
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0033 0.0056 0.004
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0041 0.0109 0.0099
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0075 0.0138
Trypanosoma brucei heat shock protein, putative 0.0098 0.0484 0.1266
Schistosoma mansoni jumonji domain containing protein 0.0396 0.2466 0.2449
Schistosoma mansoni hypothetical protein 0.0059 0.0229 0.0208
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0072 0.0314 0.0293
Onchocerca volvulus Alhambra homolog 0.0059 0.0229 0.0261
Loa Loa (eye worm) MBCTL1 0.0167 0.0946 0.1335
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0156 0.0869 0.282
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0044 0.0128 0.027
Trichomonas vaginalis CAMK family protein kinase 0.0573 0.3643 0.4563
Brugia malayi beta-lactamase 0.0036 0.0075 0.0077
Mycobacterium tuberculosis Probable dehydrogenase 0.1092 0.7094 0.8968
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0072 0.0314 0.0293
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0075 0.0061
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0044 0.0128 0.027
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0022 0.0005
Plasmodium vivax heat shock protein, putative 0.004 0.0101 0.0334
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0166 0.0938 0.2417
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0436 0.2731 0.302
Loa Loa (eye worm) hypothetical protein 0.0063 0.0256 0.0343
Loa Loa (eye worm) hypothetical protein 0.0885 0.5716 0.8199
Brugia malayi hypothetical protein 0.0061 0.0238 0.0311
Toxoplasma gondii NADPH-glutathione reductase 0.0166 0.0938 0.3049
Trypanosoma cruzi polo-like protein kinase, putative 0.0573 0.3643 1
Mycobacterium leprae Probable lipase LipE 0.0036 0.0075 0.0029
Trypanosoma cruzi trypanothione reductase, putative 0.0479 0.3017 0.8245
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1214 0.7904 1
Schistosoma mansoni inositol monophosphatase 0.0037 0.0078 0.0057
Onchocerca volvulus 0.0147 0.0811 0.0996
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0082 0.0069
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0147 0.0811 0.0791
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.1092 0.7094 0.8968
Brugia malayi Hsp90 protein 0.004 0.0101 0.0114
Loa Loa (eye worm) MH1 domain-containing protein 0.0041 0.0109 0.0131
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0072 0.0314 0.0293
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0078 0.0063
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0128 0.0125
Echinococcus granulosus lamin dm0 0.0028 0.0022 0.0002
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0082 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0284 0.172 0.2135
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0088 0.0095
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0044 0.0128 0.012
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0166 0.0938 0.2417
Schistosoma mansoni thyroid hormone receptor 0.0072 0.0314 0.0293
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0044 0.0128 0.0147
Brugia malayi nuclear receptor NHR-67 0.0034 0.0061 0.0056
Brugia malayi 6-phosphofructokinase 0.0108 0.0551 0.0762
Loa Loa (eye worm) hypothetical protein 0.0072 0.0314 0.0425
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0157 0.0152
Brugia malayi nuclear hormone receptor 0.0034 0.0061 0.0056
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0075 0.0059
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0479 0.3017 0.3776
Echinococcus granulosus geminin 0.0338 0.2085 0.23
Trypanosoma cruzi Heat shock protein 83, putative 0.0098 0.0484 0.1144
Schistosoma mansoni hypothetical protein 0.0338 0.2085 0.2068
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0061
Brugia malayi MH2 domain containing protein 0.0041 0.0109 0.0126
Echinococcus multilocularis histone acetyltransferase MYST2 0.0167 0.0946 0.1032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0072 0.0314 0.0421
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0156 0.0869 0.0849
Trypanosoma brucei heat shock protein, putative 0.0098 0.0484 0.1266
Brugia malayi F/Y-rich N-terminus family protein 0.0052 0.0183 0.0232
Echinococcus granulosus phd:f box containing protein 0.0084 0.039 0.0412
Echinococcus multilocularis Polycystic kidney disease protein 0.0061 0.0238 0.0243
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0156 0.0869 0.0946
Echinococcus multilocularis microtubule associated protein 2 0.1378 0.8997 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0238 0.0316
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0078 0.0009
Brugia malayi Pre-SET motif family protein 0.0156 0.0869 0.122
Brugia malayi hypothetical protein 0.0061 0.0238 0.0311
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0285 0.1728 0.2134
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0044 0.0128 0.0147
Brugia malayi ecdysteroid receptor 0.0072 0.0314 0.0421
Schistosoma mansoni hypothetical protein 0.0061 0.0238 0.0217
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0258 0.0236
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0072 0.0314 0.0421
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.371 0.4647
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0148 0.0819 0.0889
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0028 0.0094
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0551 0.066
Echinococcus granulosus heat shock protein 0.0098 0.0484 0.0516
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.371 0.4647
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0258 0.0265
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0156 0.0869 0.0849
Loa Loa (eye worm) hypothetical protein 0.0038 0.0088 0.01
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0179 0.1026 0.1007
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0044 0.0128 0.0153
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0157 0.0135
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.0314 0.0327
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0044 0.0128 0.0317
Mycobacterium ulcerans aldehyde dehydrogenase 0.0249 0.1492 0.8572
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0072 0.0314 0.0327
Plasmodium vivax glutathione reductase, putative 0.0479 0.3017 1
Echinococcus multilocularis heat shock protein 90 0.0078 0.0351 0.0369
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0044 0.0128 0.027
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0166 0.0938 1
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0044 0.0128 0.012
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0583 0.371 0.4647
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0072 0.0314 0.0327
Brugia malayi TAR-binding protein 0.0064 0.0258 0.034
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.0082
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.017 0.0963 0.105
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0082 0.0145
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0249 0.1492 0.1833
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0044 0.0128 0.0423
Schistosoma mansoni jumonji domain containing protein 0.0084 0.039 0.0369
Schistosoma mansoni nuclear receptor nhr-48 0.0034 0.0061 0.0039
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0104 0.0524 0.0728
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0034 0.0061 0.0039
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0075 0.0054
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0128 0.0125
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Echinococcus granulosus mannose 6 phosphate isomerase 0.0104 0.0524 0.0562
Loa Loa (eye worm) heat shock protein 75 0.004 0.0101 0.0119
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0166 0.0938 0.2521
Toxoplasma gondii Hsp90 domain-containing protein 0.004 0.0101 0.0252
Trypanosoma brucei heat shock protein, putative 0.0098 0.0484 0.1266
Loa Loa (eye worm) CXXC zinc finger family protein 0.0089 0.0429 0.0591
Loa Loa (eye worm) mbt repeat family protein 0.0147 0.0811 0.1141
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0078 0.0177
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0082 0.0069
Plasmodium falciparum mannose-6-phosphate isomerase, putative 0.0104 0.0524 0.1738
Loa Loa (eye worm) jmjC domain-containing protein 0.0084 0.039 0.0535
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0127 0.0124
Brugia malayi nuclear hormone receptor 0.0072 0.0314 0.0421
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0157 0.0152
Loa Loa (eye worm) jmjC domain-containing protein 0.0084 0.039 0.0535
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0104 0.0524 0.0728
Toxoplasma gondii histone lysine methyltransferase SET1 0.0175 0.0998 0.3251
Echinococcus granulosus chromobox protein 1 0.0144 0.0794 0.0862
Echinococcus granulosus microtubule associated protein 2 0.1378 0.8997 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.0314 0.0327
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1214 0.7904 1
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0044 0.0128 0.0147
Onchocerca volvulus 0.0036 0.0075 0.0067
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0044 0.0128 0.012
Plasmodium falciparum heat shock protein 90 0.0098 0.0484 0.1603
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0166 0.0938 0.2417
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Brugia malayi serine/threonine-protein kinase plk-2 0.0573 0.3643 0.5214
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0166 0.0938 0.5218
Schistosoma mansoni lozenge 0.0111 0.0573 0.0552
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0044 0.0127 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0128 0.0147
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0127 0.0124
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0166 0.0938 0.1022
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0271 0.0549
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.1092 0.7094 0.8968
Brugia malayi Pax transcription factor protein 2 0.0251 0.1501 0.213
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0078 0.0351 0.038
Echinococcus granulosus lipoxygenase domain containing protein 0.0061 0.0238 0.0243
Schistosoma mansoni hypothetical protein 0.0306 0.1868 0.185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0072 0.0314 0.0425
Echinococcus multilocularis lamin dm0 0.0028 0.0022 0.0002
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0484 0.1144
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0072 0.0314 0.0293
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0551 0.0591
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0034 0.0061 0.0045
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0075 0.0029
Plasmodium vivax importin-beta 2, putative 0.0029 0.0025 0.0084
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0044 0.0128 0.0125
Schistosoma mansoni smad 0.0041 0.0109 0.0088
Loa Loa (eye worm) MH2 domain-containing protein 0.0606 0.3862 0.5531
Echinococcus multilocularis smad 0.0041 0.0109 0.0099
Schistosoma mansoni protein phosphatase 2C 0.0084 0.039 0.0369
Echinococcus multilocularis Protein lozenge 0.0111 0.0573 0.0616
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0271 0.0549
Toxoplasma gondii heat shock protein HSP90 0.0098 0.0484 0.1531
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0075 0.0249
Echinococcus granulosus arachidonate 5 lipoxygenase 0.017 0.0963 0.105
Trypanosoma cruzi polo-like protein kinase, putative 0.0573 0.3643 1
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0551 0.1333
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0044 0.0128 0.0575
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0044 0.0128 0.0283
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0166 0.0938 0.2417
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0034 0.0061 0.0045
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0084 0.039 0.0883
Brugia malayi nuclear hormone receptor family member nhr-6 0.0034 0.0061 0.0056
Trichomonas vaginalis glutamate synthase, putative 0.0044 0.0128 0.0125
Brugia malayi jmjC domain containing protein 0.0318 0.1951 0.2778
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho 0.0056 0.0209 0.0199
Brugia malayi glutathione reductase 0.0479 0.3017 0.4313
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0157 0.0199
Schistosoma mansoni sex comb on midleg homolog 0.0147 0.0811 0.0791
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0551 0.053
Loa Loa (eye worm) hypothetical protein 0.0072 0.0314 0.0425
Entamoeba histolytica hypothetical protein 0.0036 0.0075 0.0127
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0044 0.0128 0.0095
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0573 0.3643 0.4036
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0075 0.0029
Giardia lamblia Grp94/Hsp90 0.0078 0.0351 0.0877
Leishmania major trypanothione reductase 0.0479 0.3017 0.8245
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0285 0.1728 0.2134
Loa Loa (eye worm) nuclear hormone receptor 0.0034 0.0061 0.0061
Toxoplasma gondii heat shock protein 90, putative 0.0098 0.0484 0.1531
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0044 0.0128 0.0125
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0028 0.0094
Loa Loa (eye worm) endoplasmin 0.0098 0.0484 0.0669
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0061 0.0039
Loa Loa (eye worm) jmjC domain-containing protein 0.0318 0.1951 0.2782
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0078 0.0018
Plasmodium vivax mannose-6-phosphate isomerase, putative 0.0104 0.0524 0.1738
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0128 0.0147
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0306 0.1868 0.2662
Echinococcus multilocularis cpg binding protein 0.0094 0.0463 0.0493
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0551 0.0635
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0078 0.0146
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0072 0.0314 0.0421
Brugia malayi steroid hormone receptor 0.0072 0.0314 0.0421
Schistosoma mansoni phosphatidylserine receptor 0.0084 0.039 0.0369
Loa Loa (eye worm) hypothetical protein 0.0072 0.0314 0.0425
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0044 0.0128 0.0147
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0044 0.0128 0.0095
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0167 0.0946 0.1032
Echinococcus multilocularis JmjC domain containing protein 4 0.0084 0.039 0.0412
Loa Loa (eye worm) hypothetical protein 0.0081 0.0372 0.051
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0075 0.0059
Schistosoma mansoni steroid hormone receptor ad4bp 0.0072 0.0314 0.0293
Schistosoma mansoni heat shock protein 0.0098 0.0484 0.0463
Trypanosoma brucei hypothetical protein, conserved 0.0044 0.0128 0.0283
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0229 0.068
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0436 0.2731 0.302
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0061 0.0045
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0157 0.0152
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0078 0.0351 0.038
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0044 0.0128 0.0095
Echinococcus granulosus lipoxygenase domain containing protein 0.0061 0.0238 0.0243
Brugia malayi tailless protein 0.0034 0.0061 0.0056
Echinococcus granulosus lysine specific demethylase 6a 0.0084 0.039 0.0412
Plasmodium vivax thioredoxin reductase, putative 0.0479 0.3017 1
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Schistosoma mansoni loxhd1 0.0061 0.0238 0.0217
Brugia malayi phosphofructokinase 0.0108 0.0551 0.0762
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0072 0.0314 0.0421
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0082 0.0067
Leishmania major heat shock protein 83-1 0.0098 0.0484 0.1144
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0285 0.1728 1
Schistosoma mansoni rab6-interacting 0.0061 0.0238 0.0217
Echinococcus granulosus nuclear receptor nhr 48 0.0034 0.0061 0.0045
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0044 0.0128 0.0423
Echinococcus granulosus chromobox protein 1 0.0144 0.0794 0.0862
Echinococcus granulosus lysine specific demethylase 5A 0.0318 0.1951 0.2151
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0166 0.0938 0.3108

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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