Detailed information for compound 1008969

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 478.824 | Formula: C9H5Br4NS
  • H donors: 1 H acceptors: 0 LogP: 5.66 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSc1c(Br)[nH]c2c1c(Br)c(c(c2)Br)Br
  • InChi: 1S/C9H5Br4NS/c1-15-8-5-4(14-9(8)13)2-3(10)6(11)7(5)12/h2,14H,1H3
  • InChiKey: DXKZUNOMDOVWPE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0225 0.0229
Brugia malayi glutathione reductase 0.0047 0.1528 0.1555
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0251 0.164
Echinococcus granulosus Niemann Pick C1 protein 0.0147 0.5674 0.5774
Onchocerca volvulus Bile acid receptor homolog 0.0166 0.6451 0.6451
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0225 0.0229
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0251 0.164
Onchocerca volvulus 0.005 0.1665 0.1665
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.1528 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0343 0.0349
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0251 0.164
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0601 0.2744
Echinococcus multilocularis Niemann Pick C1 protein 0.0103 0.3842 0.391
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.1528 0.1555
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0601 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0982 0.0999
Brugia malayi CHE-14 protein 0.0044 0.1405 0.143
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0601 1
Schistosoma mansoni patched 1 0.0044 0.1405 0.236
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0601 1
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0251 0.164
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.453 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0343 0.0721
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0225 0.0229
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.1449 0.1475
Brugia malayi Thioredoxin reductase 0.0047 0.1528 0.1555
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0615 0.4026
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0341 0.2233
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0251 0.0255
Schistosoma mansoni hypothetical protein 0.0011 0.0041 0.0068
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0887 0.149
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0103 0.3842 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0341 0.0347
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0251 0.4168
Loa Loa (eye worm) glutathione reductase 0.0047 0.1528 0.1555
Echinococcus multilocularis expressed conserved protein 0.0097 0.3583 0.3646
Echinococcus granulosus Protein patched homolog 1 0.0044 0.1405 0.143
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0343 0.265
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0601 0.1327
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0343 0.57
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0251 0.164
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0615 0.4026
Loa Loa (eye worm) hypothetical protein 0.0054 0.1817 0.1849
Leishmania major hypothetical protein, conserved 0.0025 0.0615 0.2855
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0251 0.4168
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0071 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.1405 0.1405
Loa Loa (eye worm) hypothetical protein 0.005 0.1634 0.1663
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0041 0.0041
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0154 0.5953 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0343 0.0892
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0041 0.0041
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0601 1
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0251 0.0251
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0299 0.0114
Brugia malayi hypothetical protein 0.0247 0.9827 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.453 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0839 0.0854
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0601 0.0612
Leishmania major trypanothione reductase 0.0047 0.1528 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0251 0.164
Schistosoma mansoni hypothetical protein 0.0016 0.0225 0.0378
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0601 0.0612
Schistosoma mansoni hypothetical protein 0.0043 0.1339 0.2249
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0343 0.2242
Plasmodium falciparum glutathione reductase 0.0047 0.1528 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0601 1
Schistosoma mansoni hypothetical protein 0.0016 0.0225 0.0378
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0251 0.7312
Echinococcus granulosus histone acetyltransferase KAT2B 0.0149 0.5774 0.5876
Loa Loa (eye worm) hypothetical protein 0.0166 0.6451 0.6564
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.357 0.3633
Schistosoma mansoni hypothetical protein 0.0043 0.1339 0.2249
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0982 0.0999
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0225 0.0229
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.1665 0.1694
Loa Loa (eye worm) hypothetical protein 0.0025 0.0601 0.0612
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.9827 1
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0615 0.4026
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0251 0.1938
Mycobacterium ulcerans hypothetical protein 0.0025 0.0601 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0343 0.2242
Trichomonas vaginalis set domain proteins, putative 0.0251 1 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0615 0.4026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0887 0.149
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0343 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0299 0.0114
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0887 0.0903
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0601 0.0612
Loa Loa (eye worm) hypothetical protein 0.0016 0.0225 0.0229
Brugia malayi Pre-SET motif family protein 0.0032 0.0887 0.0903
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0251 0.164
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.453 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0601 0.0612
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0251 0.164
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0343 0.0343
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.4033 0.8837
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.1405 0.143
Loa Loa (eye worm) hypothetical protein 0.0019 0.0341 0.0347
Schistosoma mansoni hypothetical protein 0.0016 0.0225 0.0378
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.1293 0.3365
Onchocerca volvulus 0.0032 0.0887 0.0887
Plasmodium falciparum thioredoxin reductase 0.0047 0.1528 1
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.9827 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0105 0.3908 0.6565
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.4033 0.8837
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0251 0.7342
Brugia malayi acetyltransferase, GNAT family protein 0.0154 0.5953 0.6058
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0887 0.149
Plasmodium falciparum thioredoxin reductase 0.0016 0.0251 0.164
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0225 0.0229
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.357 0.3633
Loa Loa (eye worm) hypothetical protein 0.0019 0.0341 0.0347
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0251 0.164
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0251 0.164
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0251 0.164
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0251 0.0421
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.1528 0.1555
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0343 0.0349
Loa Loa (eye worm) hypothetical protein 0.0019 0.0341 0.0347
Brugia malayi hypothetical protein 0.0016 0.0246 0.025
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0343 0.0349
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.1528 0.1555
Schistosoma mansoni hypothetical protein 0.0016 0.0225 0.0378
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.357 0.3633
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.1634 0.1663
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0343 0.2242
Treponema pallidum NADH oxidase 0.0016 0.0251 0.7312
Trypanosoma brucei trypanothione reductase 0.0047 0.1528 1
Plasmodium vivax glutathione reductase, putative 0.0047 0.1528 1
Schistosoma mansoni ap endonuclease 0.0019 0.0343 0.0576
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0601 0.0819
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0887 0.0903
Loa Loa (eye worm) acetyltransferase 0.0154 0.5953 0.6058
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0343 0.0349
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0251 0.164
Echinococcus granulosus expressed conserved protein 0.0097 0.3583 0.3646
Loa Loa (eye worm) hypothetical protein 0.0103 0.3842 0.391
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0341 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.1449 0.9485
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0601 0.1565
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.4033 0.8837
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.357 0.3633
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0225 0.0229
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.1449 0.9485
Brugia malayi ecdysteroid receptor 0.0166 0.6451 0.6564
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0251 0.164
Echinococcus multilocularis GPCR, family 2 0.0016 0.0225 0.0229
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0341 0.2233
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0071 0.0072
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0251 0.164
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0341 0.5677
Loa Loa (eye worm) hypothetical protein 0.0247 0.9827 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0343 0.2242
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.1449 0.1449
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.1449 0.1449
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0154 0.5953 0.6058
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0601 0.1327
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0225 0.0229
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0251 0.164
Echinococcus multilocularis protein dispatched 1 0.005 0.1664 0.1693
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0601 0.2744
Loa Loa (eye worm) hypothetical protein 0.0019 0.0341 0.0347
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0887 0.149
Schistosoma mansoni hypothetical protein 0.005 0.1665 0.2796
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0299 0.0114
Toxoplasma gondii thioredoxin reductase 0.0047 0.1528 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0887 0.0903
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.4033 0.8837
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0251 0.0255
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.1293 1
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.1405 0.143
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0343 0.2242
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.1528 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0887 0.5806
Loa Loa (eye worm) hypothetical protein 0.0025 0.0601 0.0612
Mycobacterium tuberculosis Probable reductase 0.0108 0.4033 0.8837
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0601 0.1565
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.1405 0.143
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.357 0.3633
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.1634 0.1663
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0251 0.4168
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0601 0.0819
Schistosoma mansoni hypothetical protein 0.0034 0.0982 0.165
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0251 0.7312
Plasmodium falciparum glutathione reductase 0.0016 0.0251 0.164
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0251 0.164
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0251 0.164
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.357 0.5997
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.357 0.5997
Loa Loa (eye worm) hypothetical protein 0.0025 0.0615 0.0626
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0343 1
Onchocerca volvulus 0.0025 0.0601 0.0601
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0601 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.1293 0.8462
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0601 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.357 0.3633
Brugia malayi hypothetical protein 0.0025 0.0615 0.0626
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0341 0.0212
Schistosoma mansoni hypothetical protein 0.0043 0.1339 0.2249
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0601 0.1565
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0251 0.0251
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0251 0.0255
Echinococcus granulosus GPCR family 2 0.0016 0.0225 0.0229
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0221 0.8734 0.8888
Plasmodium vivax SET domain protein, putative 0.0032 0.0887 0.5806
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.1528 0.2985
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.4033 0.8902
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0615 0.4026
Brugia malayi Pre-SET motif family protein 0.0221 0.8734 0.8888
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.357 0.5997
Schistosoma mansoni hypothetical protein 0.0043 0.1339 0.2249
Schistosoma mansoni survival motor neuron protein 0.005 0.1665 0.2796
Brugia malayi Niemann-Pick C1 protein precursor 0.0103 0.3842 0.391
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.4033 0.8837
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0601 0.2744
Schistosoma mansoni ap endonuclease 0.0019 0.0343 0.0576
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.1449 0.9485
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0251 0.164
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0615 0.4026
Echinococcus multilocularis Niemann Pick C1 protein 0.0147 0.5674 0.5774
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0343 0.0215
Echinococcus granulosus Niemann Pick C1 protein 0.0103 0.3842 0.391
Toxoplasma gondii exonuclease III APE 0.0019 0.0343 0.2242
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0251 0.164
Loa Loa (eye worm) hypothetical protein 0.0044 0.1405 0.143
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0615 0.4026
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0343 0.0343
Echinococcus multilocularis protein patched 0.0044 0.1405 0.143
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.1634 0.1663
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0299 0.0114
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.453 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0887 0.0903

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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