Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.037 | 0.3673 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0071 | 0.0166 |
Brugia malayi | MH2 domain containing protein | 0.0018 | 0.008 | 0.0204 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0026 | 0.0163 | 0.0417 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0018 | 0.008 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0692 | 0.1772 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0026 | 0.0163 | 0.5454 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0028 | 0.0187 | 0.0944 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0026 | 0.0171 | 0.0855 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0147 | 0.1401 | 0.3586 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0039 | 0.0304 | 0.1566 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0078 | 0.0692 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0147 | 0.1401 | 0.1392 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0022 | 0.0126 | 0.1691 |
Schistosoma mansoni | smad | 0.0018 | 0.008 | 0.019 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0026 | 0.0163 | 0.0153 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0071 | 0.0182 |
Loa Loa (eye worm) | beta-lactamase | 0.0078 | 0.0692 | 0.1772 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0026 | 0.0162 | 0.0308 |
Leishmania major | hypothetical protein, conserved | 0.0078 | 0.0692 | 0.3638 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0147 | 0.1401 | 0.1392 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0015 | 0.0054 | 0.0089 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.0692 | 1 |
Brugia malayi | beta-lactamase | 0.0078 | 0.0692 | 0.1772 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.0692 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0052 | 0.0435 | 0.2268 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0026 | 0.0163 | 0.0417 |
Echinococcus granulosus | tar DNA binding protein | 0.0274 | 0.2697 | 0.269 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0257 | 0.2524 | 0.646 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0195 | 0.1884 | 1 |
Brugia malayi | TAR-binding protein | 0.0274 | 0.2697 | 0.6905 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0071 | 0.0061 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0026 | 0.0163 | 0.0417 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0026 | 0.0163 | 0.2241 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0019 | 0.0093 | 0.0441 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0692 | 0.1772 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0071 | 0.0061 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0052 | 0.0435 | 0.6234 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.005 | 0.0412 | 0.1054 |
Schistosoma mansoni | hypothetical protein | 0.037 | 0.3673 | 1 |
Echinococcus multilocularis | geminin | 0.037 | 0.3673 | 0.3667 |
Wolbachia endosymbiont of Brugia malayi | bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase | 0.0011 | 0.001 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0274 | 0.2697 | 0.7335 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0028 | 0.0187 | 0.0358 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0048 | 0.0387 | 0.0966 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0017 | 0.0079 | 0.1012 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0078 | 0.0692 | 0.1861 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0078 | 0.0692 | 0.1379 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0195 | 0.1884 | 0.1876 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0052 | 0.0133 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.0692 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0257 | 0.2524 | 0.646 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0078 | 0.0692 | 0.1379 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0991 | 1 | 1 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0028 | 0.0187 | 0.2595 |
Loa Loa (eye worm) | hypothetical protein | 0.0393 | 0.3907 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0147 | 0.1401 | 0.3796 |
Toxoplasma gondii | ABC1 family protein | 0.0078 | 0.0692 | 0.3638 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0052 | 0.0435 | 0.6234 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0496 | 0.4954 | 1 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0026 | 0.0171 | 0.0855 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.0692 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0078 | 0.0692 | 1 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0017 | 0.0076 | 0.035 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0195 | 0.1884 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.029 | 0.0765 |
Loa Loa (eye worm) | RNA binding protein | 0.0274 | 0.2697 | 0.6905 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0018 | 0.008 | 0.007 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0026 | 0.0171 | 0.0855 |
Brugia malayi | MH2 domain containing protein | 0.0257 | 0.2524 | 0.646 |
Brugia malayi | Smad1 | 0.0018 | 0.008 | 0.0204 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0018 | 0.008 | 0.007 |
Plasmodium vivax | hypothetical protein, conserved | 0.0078 | 0.0692 | 1 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0017 | 0.0079 | 0.0368 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0026 | 0.0163 | 0.3594 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0018 | 0.008 | 0.019 |
Trichomonas vaginalis | chaperonin, putative | 0.0026 | 0.0163 | 0.2241 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0052 | 0.0435 | 0.1114 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0078 | 0.0692 | 0.3638 |
Echinococcus multilocularis | smad | 0.0018 | 0.008 | 0.007 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0025 | 0.0153 | 0.0391 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0052 | 0.0435 | 0.2268 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0078 | 0.0692 | 0.1379 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0028 | 0.0187 | 0.0944 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0268 | 0.0687 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0274 | 0.2697 | 0.6905 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0071 | 0.0061 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0018 | 0.008 | 0.0204 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0052 | 0.0435 | 0.6234 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0195 | 0.1884 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0274 | 0.2697 | 0.7335 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0052 | 0.0435 | 0.116 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0026 |
Brugia malayi | aldehyde dehydrogenase | 0.0011 | 0.001 | 0.0026 |
Mycobacterium ulcerans | lipase LipD | 0.0078 | 0.0692 | 0.3638 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0026 | 0.0171 | 0.235 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0026 | 0.0163 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0692 | 0.1772 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0028 | 0.0187 | 0.2595 |
Loa Loa (eye worm) | fatty acid synthase | 0.0026 | 0.0167 | 0.0427 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0078 | 0.0692 | 0.1379 |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.008 | 0.0204 |
Loa Loa (eye worm) | aldehyde dehydrogenase | 0.0011 | 0.001 | 0.0026 |
Echinococcus granulosus | geminin | 0.037 | 0.3673 | 0.3667 |
Brugia malayi | beta-lactamase family protein | 0.0078 | 0.0692 | 0.1772 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0078 | 0.0692 | 0.0682 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0071 | 0.0061 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0438 | 0.1122 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0019 | 0.0095 | 0.0171 |
Schistosoma mansoni | tar DNA-binding protein | 0.0274 | 0.2697 | 0.7335 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0052 | 0.0435 | 0.0425 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0026 | 0.0162 | 0.0308 |
Brugia malayi | hypothetical protein | 0.0038 | 0.029 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0354 | 0.0905 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0071 | 0.0061 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.0692 | 0.1379 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0435 | 0.6234 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0692 | 0.1772 |
Echinococcus multilocularis | Smad4 | 0.0018 | 0.008 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0071 | 0.0182 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0021 | 0.0118 | 0.0574 |
Brugia malayi | hypothetical protein | 0.0393 | 0.3907 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0393 | 0.3907 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0393 | 0.3907 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0857 | 0.8641 | 0.864 |
Treponema pallidum | gamma-glutamyl phosphate reductase | 0.0011 | 0.001 | 0.5 |
Mycobacterium ulcerans | polyketide synthase | 0.0028 | 0.0187 | 0.0944 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0071 | 0.0182 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0195 | 0.1884 | 0.1876 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0022 | 0.0121 | 0.0225 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0195 | 0.1884 | 0.3791 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0268 | 0.0687 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0017 | 0.0079 | 0.0368 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0078 | 0.0692 | 0.1379 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0026 | 0.0163 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0274 | 0.2697 | 0.269 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0028 | 0.0187 | 0.0358 |
Onchocerca volvulus | 0.0046 | 0.037 | 0.0923 | |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.008 | 0.0204 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0026 | 0.0171 | 0.0436 |
Loa Loa (eye worm) | TAR-binding protein | 0.0274 | 0.2697 | 0.6905 |
Mycobacterium leprae | conserved hypothetical protein | 0.0078 | 0.0692 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0052 | 0.0435 | 0.1114 |
Echinococcus granulosus | smad | 0.0018 | 0.008 | 0.007 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0071 | 0.0166 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0195 | 0.1884 | 0.5115 |
Mycobacterium leprae | Probable lipase LipE | 0.0078 | 0.0692 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0078 | 0.0692 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.029 | 0.028 |
Onchocerca volvulus | 0.0078 | 0.0692 | 0.175 | |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0021 | 0.0118 | 0.0574 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.029 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0078 | 0.0692 | 0.1772 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.029 | 1 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0026 | 0.0163 | 0.0153 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0052 | 0.0435 | 0.6234 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0013 | 0.0037 | 0.0144 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0018 | 0.008 | 0.007 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0274 | 0.2697 | 0.6905 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0022 | 0.0126 | 0.0234 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0078 | 0.0692 | 0.1772 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.029 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0274 | 0.2697 | 0.7335 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0026 | 0.0163 | 0.0417 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0071 | 0.0061 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0078 | 0.0692 | 0.3638 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0147 | 0.1401 | 0.3586 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0052 | 0.0435 | 0.0425 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0147 | 0.1401 | 0.3796 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0438 | 0.1122 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0435 | 0.6234 |
Echinococcus granulosus | Smad4 | 0.0018 | 0.008 | 0.007 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0025 | 0.0153 | 0.0289 |
Onchocerca volvulus | 0.0078 | 0.0692 | 0.175 | |
Mycobacterium ulcerans | hypothetical protein | 0.0078 | 0.0692 | 0.3638 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0039 | 0.0304 | 0.0594 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0052 | 0.0435 | 0.0425 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0078 | 0.0692 | 0.1861 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0147 | 0.1401 | 0.1392 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0018 | 0.008 | 0.0204 |
Onchocerca volvulus | 0.0025 | 0.0153 | 0.0366 | |
Echinococcus multilocularis | neuropeptide s receptor | 0.0991 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0692 | 0.1772 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0026 | 0.0163 | 0.2241 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0071 | 0.0182 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0026 | 0.0171 | 0.0324 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0026 | 0.0171 | 0.235 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0028 | 0.0187 | 0.0944 |
Schistosoma mansoni | Smad4 | 0.0018 | 0.008 | 0.019 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0435 | 0.6234 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0026 | 0.0163 | 0.0815 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0078 | 0.0692 | 0.1379 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.0692 | 0.1379 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0052 | 0.0435 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0071 | 0.0166 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0078 | 0.0692 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0052 | 0.0435 | 0.2268 |
Brugia malayi | Succinate semialdehyde dehydrogenase, mitochondrial precursor | 0.0011 | 0.001 | 0.0026 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0052 | 0.0435 | 0.0425 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0026 | 0.0171 | 0.0324 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0438 | 0.1122 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0026 | 0.0171 | 0.0324 |
Schistosoma mansoni | tar DNA-binding protein | 0.0274 | 0.2697 | 0.7335 |
Mycobacterium ulcerans | polyketide synthase | 0.0026 | 0.0171 | 0.0855 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0078 | 0.0692 | 0.0682 |
Brugia malayi | RNA binding protein | 0.0274 | 0.2697 | 0.6905 |
Onchocerca volvulus | 0.0078 | 0.0692 | 0.175 | |
Loa Loa (eye worm) | aldehyde dehydrogenase 4 | 0.0011 | 0.001 | 0.0026 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0028 | 0.0187 | 0.2595 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0195 | 0.1884 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0147 | 0.1401 | 0.3796 |
Loa Loa (eye worm) | acyl carrier protein | 0.0012 | 0.0025 | 0.0064 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.029 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0991 | 1 | 1 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0039 | 0.0304 | 0.0594 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0078 | 0.0692 | 0.1379 |
Mycobacterium ulcerans | thioesterase TesA | 0.0022 | 0.0126 | 0.0615 |
Mycobacterium ulcerans | beta-lactamase | 0.0078 | 0.0692 | 0.3638 |
Schistosoma mansoni | smad1 5 8 and | 0.0018 | 0.008 | 0.019 |
Brugia malayi | Aldehyde dehydrogenase protein 4 | 0.0011 | 0.001 | 0.0026 |
Brugia malayi | beta-lactamase family protein | 0.0078 | 0.0692 | 0.1772 |
Trypanosoma brucei | protein kinase, putative | 0.0052 | 0.0435 | 0.6234 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.029 | 0.0765 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0195 | 0.1884 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0435 | 0.6234 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0026 | 0.0163 | 0.0815 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.029 | 0.028 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0268 | 0.0705 |
Loa Loa (eye worm) | delta-1-pyrroline-5-carboxylate dehydrogenase | 0.0011 | 0.001 | 0.0026 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.0692 | 0.1379 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0071 | 0.0166 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0147 | 0.1401 | 0.1392 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0438 | 0.1122 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0692 | 0.1772 |
Loa Loa (eye worm) | Smad1 | 0.0018 | 0.008 | 0.0204 |
Brugia malayi | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor | 0.0011 | 0.001 | 0.0026 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0153 | 0.0391 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0026 | 0.0163 | 0.0417 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0028 | 0.0187 | 0.0358 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0021 | 0.0118 | 0.1578 |
Schistosoma mansoni | smad1 5 8 and | 0.0018 | 0.008 | 0.019 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0195 | 0.1884 | 0.5115 |
Mycobacterium ulcerans | thioesterase | 0.0022 | 0.0126 | 0.0615 |
Schistosoma mansoni | smad1 5 8 and | 0.0018 | 0.008 | 0.019 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.0692 | 1 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0026 | 0.0163 | 0.2241 |
Onchocerca volvulus | Huntingtin homolog | 0.0393 | 0.3907 | 1 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0026 | 0.0171 | 0.0855 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0052 | 0.0435 | 0.6234 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0039 | 0.0304 | 0.4304 |
Brugia malayi | MH2 domain containing protein | 0.0018 | 0.008 | 0.0204 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.