Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.024 | 0.0283 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0099 | 0.1023 | 0.5293 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0337 | 0.0445 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0337 | 0.9493 |
Onchocerca volvulus | 0.016 | 0.1718 | 1 | |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0022 | 0.0152 | 0.0179 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0035 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.01 | 0.0517 |
Schistosoma mansoni | coup transcription factor | 0.0022 | 0.0152 | 0.0179 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0035 | 0.0182 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.001 | 0.0021 | 0.0021 |
Brugia malayi | nuclear receptor RXR | 0.0012 | 0.0035 | 0.0182 |
Echinococcus multilocularis | lamin | 0.003 | 0.024 | 0.024 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0337 | 0.9493 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.001 | 0.0021 | 0.0109 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0022 | 0.0152 | 0.0785 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0035 | 0.0183 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.01 | 0.0517 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.024 | 0.0283 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.01 | 0.0517 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0017 | 0.01 | 1 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0337 | 0.174 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0152 | 0.0786 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0757 | 0.8496 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0017 | 0.01 | 0.0118 |
Brugia malayi | hypothetical protein | 0.016 | 0.1718 | 0.8889 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0019 | 0.0118 | 0.0118 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0015 | 0.0072 | 0.2036 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.001 | 0.0021 | 0.0021 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0016 | 0.0085 | 0.0437 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.1023 | 0.1204 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0022 | 0.0152 | 0.0179 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0022 | 0.0152 | 0.0785 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0337 | 0.1742 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0066 | 0.0654 | 0.077 |
Brugia malayi | ecdysteroid receptor | 0.0022 | 0.0152 | 0.0785 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0017 | 0.01 | 0.2046 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0337 | 0.0445 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0022 | 0.0152 | 0.0786 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.001 | 0.0021 | 0.0123 |
Schistosoma mansoni | lamin | 0.003 | 0.024 | 0.0283 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0337 | 0.0396 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0035 | 0.0183 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.004 | 0.0355 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0337 | 0.0445 |
Brugia malayi | nuclear receptor NHR-88 | 0.0022 | 0.0152 | 0.0785 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0017 | 0.01 | 0.0118 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0066 | 0.0654 | 0.077 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0337 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0066 | 0.0654 | 0.3386 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0014 | 0.0067 | 0.0067 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.001 | 0.0021 | 0.0025 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0337 | 0.9493 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Leishmania major | alpha glucosidase II subunit, putative | 0.004 | 0.0355 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.0337 | 0.0445 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0015 | 0.0072 | 0.2036 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0337 | 0.1743 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0061 | 0.0314 |
Echinococcus granulosus | lamin | 0.003 | 0.024 | 0.0283 |
Echinococcus multilocularis | musashi | 0.003 | 0.024 | 0.024 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0337 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0021 | 0.0021 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.001 | 0.0021 | 0.0109 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0099 | 0.1023 | 0.5293 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0022 | 0.0152 | 0.0152 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0022 | 0.0152 | 0.0179 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0035 | 0.0182 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0022 | 0.0152 | 0.0785 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0022 | 0.0152 | 0.0152 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0337 | 0.0445 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.024 | 0.1244 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0022 | 0.0152 | 0.0786 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0757 | 0.8496 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0022 | 0.0152 | 0.0786 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.004 | 0.0355 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0022 | 0.0152 | 0.0883 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.01 | 0.0517 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0152 | 0.0786 |
Onchocerca volvulus | 0.0103 | 0.1078 | 0.6273 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.1023 | 0.1204 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.1938 | 0.2281 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0022 | 0.0152 | 0.0785 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0022 | 0.0152 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0337 | 0.1743 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0022 | 0.0152 | 0.0785 |
Brugia malayi | nuclear receptor NHR-67 | 0.001 | 0.0021 | 0.0109 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0179 | 0.1933 | 1 |
Brugia malayi | tailless protein | 0.001 | 0.0021 | 0.0109 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.004 | 0.0355 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0022 | 0.0152 | 0.0179 |
Echinococcus granulosus | tumor protein p63 | 0.0357 | 0.396 | 0.4661 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0337 | 0.9493 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0019 | 0.0118 | 0.0138 |
Brugia malayi | intermediate filament protein | 0.003 | 0.024 | 0.1243 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0022 | 0.0152 | 0.0152 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.001 | 0.0021 | 0.0025 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0337 | 0.1743 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.0337 | 0.0445 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0337 | 0.1742 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0012 | 0.0035 | 0.0042 |
Onchocerca volvulus | 0.0027 | 0.0213 | 0.1237 | |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0152 | 0.0786 |
Trypanosoma brucei | glycosyl hydrolase-like protein | 0.0015 | 0.0072 | 0.2036 |
Onchocerca volvulus | 0.0022 | 0.0152 | 0.0883 | |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0337 | 0.0396 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0234 | 0.1212 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.01 | 0.0517 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0022 | 0.0152 | 0.0786 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0012 | 0.0035 | 0.0041 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0022 | 0.0152 | 0.0786 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.004 | 0.0355 | 1 |
Onchocerca volvulus | 0.003 | 0.024 | 0.1399 | |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.01 | 0.0517 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0065 | 0.0637 | 0.075 |
Brugia malayi | jmjC domain containing protein | 0.0066 | 0.0654 | 0.3385 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0022 | 0.0152 | 0.0785 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.001 | 0.0021 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0337 | 0.1743 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Onchocerca volvulus | 0.0038 | 0.0337 | 0.196 | |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0337 | 0.0396 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0022 | 0.0152 | 0.0786 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0022 | 0.0152 | 0.0785 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.01 | 0.2815 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0015 | 0.0072 | 0.0374 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0337 | 0.9484 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0058 | 0.0558 | 0.0656 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0355 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0337 | 0.9493 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0015 | 0.0072 | 0.2036 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.01 | 0.0517 |
Brugia malayi | ecdysone receptor | 0.001 | 0.0021 | 0.0109 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.0337 | 0.0445 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0022 | 0.0152 | 0.0152 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0675 | 0.7567 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0337 | 0.6901 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.1023 | 0.1204 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.001 | 0.0021 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.004 | 0.0355 | 0.0418 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.0035 | 0.0041 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0015 | 0.0072 | 0.2036 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0022 | 0.0152 | 0.0786 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.001 | 0.0021 | 0.0025 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0015 | 0.0072 | 0.2036 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.1023 | 0.1023 |
Loa Loa (eye worm) | DR-78 | 0.001 | 0.0021 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0 | 0.0001 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0355 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0022 | 0.0152 | 0.0152 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0022 | 0.0152 | 0.0179 |
Onchocerca volvulus | 0.001 | 0.0021 | 0.0123 | |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0072 | 0.0374 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0337 | 0.1742 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0498 | 0.2578 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.001 | 0.0021 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.01 | 0.0517 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0337 | 0.9484 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0022 | 0.0152 | 0.0179 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0022 | 0.0152 | 0.0785 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0355 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0337 | 0.1743 |
Echinococcus multilocularis | geminin | 0.0179 | 0.1938 | 0.1938 |
Brugia malayi | steroid hormone receptor | 0.0022 | 0.0152 | 0.0785 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.004 | 0.0355 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0015 | 0.0072 | 0.2036 |
Schistosoma mansoni | alpha-glucosidase | 0.0154 | 0.1651 | 0.1943 |
Echinococcus multilocularis | tumor protein p63 | 0.0357 | 0.396 | 0.396 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0022 | 0.0152 | 0.0785 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0021 | 0.0025 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0022 | 0.0152 | 0.0786 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0035 | 0.0182 |
Schistosoma mansoni | alpha glucosidase | 0.004 | 0.0355 | 0.0417 |
Brugia malayi | CXXC zinc finger family protein | 0.0027 | 0.0213 | 0.1099 |
Schistosoma mansoni | protein phosphatase 2C | 0.0017 | 0.01 | 0.0118 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.023 | 0.0271 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.024 | 0.1243 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0179 | 0.1933 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0022 | 0.0152 | 0.0179 |
Onchocerca volvulus | 0.0038 | 0.0337 | 0.196 | |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0152 | 0.0786 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0152 | 0.0786 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0337 | 0.1743 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0014 | 0.0067 | 0.0079 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0022 | 0.0152 | 0.0785 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0065 | 0.0637 | 0.0637 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0152 | 0.0785 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.01 | 0.0517 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.001 | 0.0021 | 0.0025 |
Leishmania major | glycosyl hydrolase-like protein | 0.0015 | 0.0072 | 0.2036 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0337 | 0.0445 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.004 | 0.0355 | 0.0355 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.01 | 0.0517 |
Onchocerca volvulus | 0.0038 | 0.0337 | 0.196 | |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.001 | 0.0021 | 0.011 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0021 | 0.0109 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0337 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0066 | 0.0654 | 0.077 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0017 | 0.01 | 0.01 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.001 | 0.0021 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0337 | 0.0396 |
Brugia malayi | Nuclear hormone receptor E75 | 0.001 | 0.0021 | 0.0109 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0337 | 0.9484 |
Schistosoma mansoni | nuclear receptor | 0.001 | 0.0021 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0035 | 0.0183 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0337 | 0.0445 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0017 | 0.01 | 0.0118 |
Schistosoma mansoni | nuclear receptor | 0.001 | 0.0021 | 0.0025 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0008 | 0 | 0.0001 |
Brugia malayi | hypothetical protein | 0.001 | 0.0021 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0 | 0.0001 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0017 | 0.01 | 0.2815 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.001 | 0.0021 | 0.0025 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0337 | 0.0337 |
Schistosoma mansoni | cpg binding protein | 0.0027 | 0.0213 | 0.025 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0022 | 0.0152 | 0.0179 |
Schistosoma mansoni | lamin | 0.003 | 0.024 | 0.0283 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.024 | 0.1244 |
Schistosoma mansoni | jumonji domain containing protein | 0.0017 | 0.01 | 0.0118 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.004 | 0.0355 | 0.1836 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0022 | 0.0152 | 0.0179 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0022 | 0.0152 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1718 | 0.8889 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0675 | 0.7567 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0022 | 0.0152 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0152 | 0.0786 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0179 | 0.1933 | 0.1933 |
Schistosoma mansoni | jumonji domain containing protein | 0.0065 | 0.0637 | 0.075 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0022 | 0.0152 | 0.0179 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0021 | 0.0109 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0021 | 0.0025 |
Onchocerca volvulus | Uncharacterized family 31 glucosidase KIAA1161 homolog | 0.0015 | 0.0072 | 0.042 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.004 | 0.0355 | 0.7269 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.024 | 0.1244 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.023 | 0.023 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0065 | 0.0637 | 0.0637 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0179 | 0.1933 | 0.1933 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0152 | 0.0786 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0067 | 0.0345 |
Onchocerca volvulus | 0.0013 | 0.0048 | 0.028 | |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0337 | 0.0445 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0355 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0 | 0.0001 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0337 | 0.1743 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0022 | 0.0152 | 0.0785 |
Brugia malayi | Nuclear hormone receptor E75 | 0.001 | 0.0021 | 0.0109 |
Plasmodium vivax | JmjC domain containing protein | 0.0017 | 0.01 | 0.2965 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.1023 | 0.1204 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0022 | 0.0152 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0 | 0.0001 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0337 | 0.0445 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0017 | 0.01 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Brugia malayi | nuclear receptor RXR | 0.001 | 0.0021 | 0.0109 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0027 | 0.0213 | 0.11 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0022 | 0.0152 | 0.0179 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.004 | 0.0355 | 1 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0017 | 0.01 | 0.2046 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0337 | 0.0396 |
Loa Loa (eye worm) | oxidoreductase | 0.0008 | 0 | 0.0001 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0021 | 0.0025 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0017 | 0.01 | 0.2815 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0015 | 0.0072 | 0.2036 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0015 | 0.0072 | 0.2036 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0022 | 0.0152 | 0.0883 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0022 | 0.0152 | 0.0152 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0008 | 0 | 0.0001 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0022 | 0.0152 | 0.0179 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.1023 | 0.1204 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0022 | 0.0152 | 0.0152 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0337 | 0.9493 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0337 | 0.0445 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0022 | 0.0152 | 0.0179 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0337 | 0.9493 |
Onchocerca volvulus | 0.003 | 0.024 | 0.1399 | |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0017 | 0.01 | 0.2815 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0337 | 0.0337 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.0337 | 0.0445 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0061 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0337 | 0.1743 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0035 | 0.0183 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.024 | 0.0283 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.004 | 0.0355 | 0.1835 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0022 | 0.0152 | 0.0883 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0355 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0355 | 1 |
Echinococcus multilocularis | phd:f box containing protein | 0.0017 | 0.01 | 0.01 |
Onchocerca volvulus | 0.0052 | 0.0498 | 0.2899 | |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0337 | 0.0445 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0337 | 0.9493 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0017 | 0.01 | 0.01 |
Schistosoma mansoni | phd/f-box containing protein | 0.0017 | 0.01 | 0.0118 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0015 | 0.0072 | 0.2036 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0015 | 0.0072 | 0.2036 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.1938 | 0.2281 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0052 | 0.0498 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0152 | 0.0786 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0022 | 0.0152 | 0.0785 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0337 | 0.9493 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0243 | 0.2665 | 0.3522 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.001 | 0.0021 | 0.0025 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.001 | 0.0021 | 0.0109 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0022 | 0.0152 | 0.0785 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0035 | 0.0183 |
Brugia malayi | conserved hypotetical protein | 0.001 | 0.0021 | 0.0109 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0022 | 0.0152 | 0.0179 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.023 | 0.0271 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0022 | 0.0152 | 0.0152 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0012 | 0.0035 | 0.0035 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.001 | 0.0021 | 0.0021 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.1023 | 0.1023 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.001 | 0.0021 | 0.0025 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0017 | 0.01 | 0.0118 |
Brugia malayi | nuclear hormone receptor | 0.0022 | 0.0152 | 0.0785 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0085 | 0.0438 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0015 | 0.0072 | 0.2036 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0017 | 0.01 | 0.01 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.001 | 0.0021 | 0.0025 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.001 | 0.0021 | 0.0021 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0022 | 0.0152 | 0.0179 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0337 | 0.1742 |
Schistosoma mansoni | alpha-glucosidase | 0.0154 | 0.1651 | 0.1943 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0337 | 0.0445 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0012 | 0.0035 | 0.0183 |
Schistosoma mansoni | nuclear hormone receptor | 0.0022 | 0.0152 | 0.0179 |
Echinococcus granulosus | geminin | 0.0179 | 0.1938 | 0.2282 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.024 | 0.024 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0337 | 0.0396 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0021 | 0.011 |
Brugia malayi | jmjC domain containing protein | 0.0065 | 0.0637 | 0.3294 |
Onchocerca volvulus | 0.001 | 0.0021 | 0.0123 | |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.001 | 0.0021 | 0.0123 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0355 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0757 | 0.8496 | 0.8496 |
Echinococcus granulosus | FTZ F1 alpha | 0.0022 | 0.0152 | 0.0179 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0337 | 0.9484 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0022 | 0.0152 | 0.0785 |
Schistosoma mansoni | thyroid hormone receptor | 0.0022 | 0.0152 | 0.0179 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0022 | 0.0152 | 0.0785 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.023 | 0.0271 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0051 | 0.0488 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.004 | 0.0355 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0179 | 0.1933 | 0.2275 |
Echinococcus granulosus | phd:f box containing protein | 0.0017 | 0.01 | 0.0118 |
Schistosoma mansoni | zinc finger protein | 0.001 | 0.0021 | 0.0025 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0337 | 0.9493 |
Brugia malayi | hypothetical protein | 0.001 | 0.0021 | 0.0109 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.