Detailed information for compound 1011313

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 389.47 | Formula: C22H19N3O2S
  • H donors: 3 H acceptors: 2 LogP: 3.98 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(cc1)C1CC(=NN1C(=S)Nc1ccccc1)c1ccccc1O
  • InChi: 1S/C22H19N3O2S/c26-17-12-10-15(11-13-17)20-14-19(18-8-4-5-9-21(18)27)24-25(20)22(28)23-16-6-2-1-3-7-16/h1-13,20,26-27H,14H2,(H,23,28)
  • InChiKey: CGZGEJSUZRVTIR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0023 0.0072 0.019
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Onchocerca volvulus 0.0015 0.0008 0.0021
Schistosoma mansoni biogenic amine receptor 0.0023 0.0072 0.028
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0023 0.0072 0.0103
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0409 0.069
Echinococcus multilocularis G protein coupled receptor 139 0.0023 0.0072 0.0103
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0023 0.0072 0.0171
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0023 0.0072 0.0103
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0038 0.0208 0.0344
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0091 0.0091
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0012 0.0045
Schistosoma mansoni hypothetical protein 0.0023 0.0072 0.028
Brugia malayi photoreceptor-specific nuclear receptor 0.0053 0.0335 0.0335
Echinococcus granulosus importin subunit beta 1 0.0029 0.0125 0.0298
Onchocerca volvulus 0.0015 0.0008 0.0021
Echinococcus granulosus somatostatin receptor 0.0023 0.0072 0.0171
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0053 0.0335 0.0482
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0011 0.0016
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0023 0.0072 0.0072
Brugia malayi AMP-binding enzyme family protein 0.0032 0.0156 0.0156
Brugia malayi PAS domain containing protein 0.0049 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0053 0.0335 0.0335
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0012 0.0017
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0125 0.018
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0318 0.8836
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0053 0.0335 0.1309
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0117 0.0169
Echinococcus granulosus neuropeptide s receptor 0.0495 0.4191 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0335 0.0335
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0023 0.0072 0.0072
Brugia malayi Pre-SET motif family protein 0.003 0.0137 0.0137
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0012 0.0045
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0072 0.0103
Brugia malayi beta-NAC-like protein 0.0035 0.0178 0.0178
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0188 0.0188
Brugia malayi Uncoordinated protein 44 0.0015 0.000000018402 0.000000018402
Brugia malayi Bromodomain containing protein 0.0079 0.056 0.056
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0038 0.0208 0.0344
Brugia malayi RNA, U transporter 1 0.0082 0.0589 0.0589
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0359 1
Brugia malayi nuclear hormone receptor 0.0053 0.0335 0.0335
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0038 0.0208 0.0344
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0038 0.0208 0.0344
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0125 0.3354
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0072 0.0171
Echinococcus granulosus tachykinin peptides receptor 99D 0.0023 0.0072 0.0171
Loa Loa (eye worm) STAT protein 0.0129 0.0995 0.0995
Onchocerca volvulus 0.0023 0.0072 0.019
Loa Loa (eye worm) hypothetical protein 0.0032 0.0156 0.0156
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0022 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0053 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0032 0.0156 0.0156
Schistosoma mansoni amine GPCR 0.0023 0.0072 0.028
Schistosoma mansoni opsin-like receptor 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0053 0.0335 0.1309
Echinococcus multilocularis orexin receptor type 2 0.0023 0.0072 0.0103
Echinococcus multilocularis snurportin 1 0.0308 0.2562 0.3683
Loa Loa (eye worm) hypothetical protein 0.0029 0.0125 0.0125
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0178 0.0178
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0038 0.0208 0.0344
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0318 0.0318
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0011 0.0011
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0038 0.0208 0.5709
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0091 0.0091
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0117 0.028
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0072 0.0103
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.1711 0.1711
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0038 0.0208 0.0344
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0012
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0038 0.0208 0.0344
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.0042
Brugia malayi AMP-binding enzyme family protein 0.0032 0.0156 0.0156
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0053 0.0335 0.1309
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0023 0.0072 0.0072
Toxoplasma gondii cytochrome p450 superfamily protein 0.0038 0.0208 0.4986
Loa Loa (eye worm) hypothetical protein 0.0047 0.0286 0.0286
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0072 0.0171
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0023 0.0072 0.028
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0091 0.0355
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0008 0.0033
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0038 0.0208 0.0344
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0409 0.1597
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0008 0.0008
Echinococcus granulosus zinc finger protein 0.0023 0.0075 0.018
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi Protein kinase domain containing protein 0.0015 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0053 0.0335 0.0335
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0012 0.0137
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0012 0.0028
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0008 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0038 0.0208 0.0344
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0038 0.0208 0.0344
Loa Loa (eye worm) hypothetical protein 0.0071 0.0491 0.0491
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0053 0.0335 0.0886
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0091 0.0355
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0072 0.028
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0008 0.0033
Leishmania major basic transcription factor 3a, putative 0.0035 0.0178 0.4268
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0058 0.0058
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0039 0.092
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0318 0.1586
Brugia malayi neuropeptide F receptor 0.0023 0.0072 0.0072
Plasmodium vivax SET domain protein, putative 0.003 0.0137 0.4911
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0023 0.0072 0.0072
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.004 0.1514
Brugia malayi G protein-coupled receptor F59B2.13 0.0023 0.0072 0.0072
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0072 0.028
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0023 0.0072 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0053 0.0335 0.0335
Brugia malayi ecdysteroid receptor 0.0053 0.0335 0.0335
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0038 0.0208 0.5
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0091 0.0091
Brugia malayi hypothetical protein 0.0026 0.0099 0.0099
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0137 0.0533
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0072 0.0171
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0117 0.0117
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.0156 0.0254
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0072 0.0171
Mycobacterium ulcerans acyl-CoA synthetase 0.0032 0.0156 0.0254
Onchocerca volvulus 0.0019 0.0042 0.0111
Leishmania major cytochrome p450-like protein 0.0038 0.0208 0.5
Echinococcus multilocularis ecdysone induced protein 78C 0.0053 0.0335 0.0482
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0409 0.069
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.004
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0053 0.0053
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0021 0.0023
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0072 0.0171
Leishmania major 4-coumarate:coa ligase-like protein 0.0032 0.0156 0.3702
Echinococcus granulosus serotonin receptor 0.0023 0.0072 0.0171
Schistosoma mansoni amine GPCR 0.0023 0.0072 0.028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0072 0.028
Entamoeba histolytica hypothetical protein 0.0035 0.0178 0.8117
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0072 0.028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0072 0.028
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0178 0.4873
Leishmania major importin beta-1 subunit, putative 0.0023 0.0077 0.1754
Toxoplasma gondii exonuclease III APE 0.0019 0.0039 0.0779
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0409 0.0976
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0188 0.027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0053 0.0335 0.0335
Echinococcus granulosus GPCR family 2 0.0016 0.0011 0.0026
Brugia malayi larval opioid receptor 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Onchocerca volvulus 0.0023 0.0072 0.019
Brugia malayi Cytochrome P450 family protein 0.0095 0.07 0.07
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0318 0.1586
Brugia malayi Dopamine receptor protein 1 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.026
Echinococcus granulosus neuropeptide receptor A26 0.0495 0.4191 1
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0038 0.0208 0.0344
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0091 0.0131
Schistosoma mansoni histamine h1 receptor 0.0023 0.0072 0.028
Entamoeba histolytica acyl-CoA synthetase, putative 0.0032 0.0156 0.7035
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.027 0.0644
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0008 0.0008
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0012 0.0045
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.027 0.134
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) acetyltransferase 0.0149 0.1174 0.1174
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0008 0.0033
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0001 0.0004
Brugia malayi Dopamine receptor protein 2 0.0023 0.0072 0.0072
Brugia malayi nuclear receptor RXR 0.0028 0.0117 0.0117
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0187 0.0446
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0318 0.7738
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0072 0.0103
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0072 0.0171
Loa Loa (eye worm) hypothetical protein 0.0053 0.0335 0.0335
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0409 0.1597
Echinococcus granulosus fmrfamide receptor 0.0023 0.0072 0.0171
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0072 0.0171
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0038 0.0208 0.0344
Schistosoma mansoni biogenic amine receptor 0.0023 0.0072 0.028
Leishmania major hypothetical protein, conserved 0.0026 0.0099 0.2287
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni thyroid hormone receptor 0.018 0.1447 0.5647
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.027 0.6534
Schistosoma mansoni biogenic amine receptor 0.0023 0.0072 0.028
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0099 0.4324
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0335 0.0335
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0335 0.0335
Echinococcus multilocularis zinc finger protein 0.0023 0.0075 0.0108
Echinococcus granulosus g protein coupled receptor 0.0023 0.0072 0.0171
Schistosoma mansoni importin beta-1 0.0029 0.0125 0.0488
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0072 0.0103
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0012 0.0017
Mycobacterium leprae putative cytochrome p450 0.0038 0.0208 1
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0072 0.0103
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0127 0.0985 0.3843
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0038 0.0208 0.0344
Schistosoma mansoni RAR-like nuclear receptor 0.0053 0.0335 0.1309
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.1174 0.1687
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0038 0.0208 0.0344
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0008 0.0033
Brugia malayi nuclear receptor RXR 0.0025 0.0091 0.0091
Onchocerca volvulus 0.0023 0.0072 0.019
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0072 0.0171
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0318 0.0759
Echinococcus granulosus orexin receptor type 2 0.0023 0.0072 0.0171
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0318 0.8836
Onchocerca volvulus 0.0023 0.0072 0.019
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0039 0.0039
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0023 0.0072 0.0103
Schistosoma mansoni hypothetical protein 0.005 0.0305 0.119
Schistosoma mansoni amine GPCR 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni steroid hormone receptor ad4bp 0.0053 0.0335 0.1309
Schistosoma mansoni neuropeptide receptor 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0072 0.0072
Brugia malayi hypoxia-induced factor 1 0.0151 0.1188 0.1188
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0039 0.0056
Loa Loa (eye worm) DR-78 0.0025 0.0091 0.0091
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0426 0.1016
Echinococcus multilocularis serotonin receptor 0.0023 0.0072 0.0103
Entamoeba histolytica Ran family GTPase 0.0021 0.0058 0.2407
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.004 0.0055
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0178 0.4873
Leishmania major GTP-binding protein, putative 0.0021 0.0058 0.1285
Brugia malayi Serotonin receptor 0.0023 0.0072 0.0072
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0091 0.0217
Schistosoma mansoni hypothetical protein 0.0023 0.0072 0.028
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0682 0.5823 1
Brugia malayi ORL1-like opioid receptor 0.0023 0.0072 0.0072
Echinococcus multilocularis dro:myosuppressin receptor 0.0023 0.0072 0.0103
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0072 0.0103
Brugia malayi jmjC domain containing protein 0.0061 0.0409 0.0409
Onchocerca volvulus 0.0448 0.3784 1
Trichomonas vaginalis ran, putative 0.0021 0.0058 0.0259
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0038 0.0208 0.0344
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0039 0.092
Schistosoma mansoni ran 0.0021 0.0058 0.0228
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0091 0.0355
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0039 0.0054
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0077 0.2003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0099 0.0099
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0409 0.1597
Schistosoma mansoni hypothetical protein 0.0021 0.0053 0.0208
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0117 0.0117
Brugia malayi RE15519p 0.0023 0.0072 0.0072
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0318 0.0457
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Echinococcus multilocularis serotonin receptor 0.0023 0.0072 0.0103
Entamoeba histolytica hypothetical protein 0.0023 0.0077 0.3304
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0099 0.2265
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0178 0.0872
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0318 0.8836
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0091 0.0131
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0023 0.0072 0.028
Schistosoma mansoni hypothetical protein 0.0015 0.0007 0.0026
Schistosoma mansoni cytochrome P450 0.0038 0.0208 0.0812
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0335 0.08
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.007 0.0273
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0008 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0072 0.0171
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0021 0.0023
Onchocerca volvulus 0.005 0.0305 0.0806
Schistosoma mansoni zinc finger protein 0.0023 0.0075 0.0294
Loa Loa (eye worm) hypothetical protein 0.0028 0.0117 0.0117
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0072 0.0072
Onchocerca volvulus 0.0023 0.0072 0.019
Onchocerca volvulus 0.0023 0.0072 0.019
Echinococcus granulosus g-protein coupled receptor 0.0023 0.0072 0.0171
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0409 0.1597
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0072 0.0072
Trichomonas vaginalis set domain proteins, putative 0.024 0.1965 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0091 0.0241
Mycobacterium leprae Conserved hypothetical protein 0.0038 0.0208 1
Echinococcus granulosus sex peptide receptor 0.0023 0.0072 0.0171
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.0042
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0058 0.1468
Loa Loa (eye worm) hypothetical protein 0.0243 0.199 0.199
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0072 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0053 0.0335 0.0335
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0335 0.0482
Echinococcus multilocularis G-protein coupled receptor, putative 0.0023 0.0072 0.0103
Schistosoma mansoni zinc finger protein 0.0015 0.0007 0.0026
Onchocerca volvulus 0.0023 0.0072 0.019
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.004 0.0055
Brugia malayi cytochrome P450 0.0038 0.0208 0.0208
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0012
Schistosoma mansoni transcription factor btf3 0.0035 0.0178 0.0697
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0072 0.0171
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0335 0.0482
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0058 0.1468
Schistosoma mansoni ap endonuclease 0.0019 0.0039 0.0153
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0023 0.0072 0.028
Echinococcus granulosus survival motor neuron protein 1 0.0243 0.199 0.4749
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.027 0.6534
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0072 0.0171
Brugia malayi G protein-coupled receptor 0.0023 0.0072 0.0072
Brugia malayi tailless protein 0.0025 0.0091 0.0091
Brugia malayi conserved hypotetical protein 0.0025 0.0091 0.0091
Onchocerca volvulus 0.0023 0.0072 0.019
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi G-protein coupled receptor 0.0023 0.0072 0.0072
Schistosoma mansoni neuropeptide receptor 0.0023 0.0072 0.028
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0058 0.0084
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0072 0.0171
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0011 0.0026
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0409 1
Mycobacterium ulcerans hypothetical protein 0.0032 0.0156 0.0254
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0038 0.0208 0.0344
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni ap endonuclease 0.0019 0.0039 0.0153
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0032 0.0156 0.0254
Trypanosoma brucei protein kinase, putative 0.0051 0.0318 0.8836
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0072 0.0103
Echinococcus multilocularis GPCR, family 2 0.0016 0.0011 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0072 0.0103
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0011 0.0016
Onchocerca volvulus 0.0032 0.0156 0.0412
Onchocerca volvulus 0.0023 0.0072 0.019
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0298 0.1163
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0023 0.0072 0.0103
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0058 0.2407
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0335 0.08
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0091 0.0217
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0392 0.0564
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0039 0.5
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0305 0.0305
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0286 0.1115
Schistosoma mansoni survival motor neuron protein 0.005 0.0305 0.119
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0318 0.1586
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0178 0.6506
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0053 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0053 0.0335 0.0335
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0022 0.0032
Loa Loa (eye worm) hypothetical protein 0.0163 0.1299 0.1299
Mycobacterium ulcerans acyl-CoA synthetase 0.0032 0.0156 0.0254
Brugia malayi hypothetical protein 0.0028 0.0117 0.0117
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0038 0.0208 0.0344
Onchocerca volvulus Protein ultraspiracle homolog 0.0053 0.0335 0.0886
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.1174 0.4581
Loa Loa (eye worm) hypothetical protein 0.0053 0.0335 0.0335
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.1117 0.2665
Loa Loa (eye worm) hypothetical protein 0.0028 0.0117 0.0117
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0178 0.8117
Brugia malayi Cytochrome P450 family protein 0.0056 0.0359 0.0359
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0117 0.0117
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0028 0.0067
Echinococcus granulosus single minded 2 0.0036 0.0188 0.0448
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0053 0.0335 0.1309
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0012 0.0092
Plasmodium falciparum importin beta, putative 0.0029 0.0125 0.557
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0012 0.0012
Schistosoma mansoni nuclear hormone receptor 0.0053 0.0335 0.1309
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0053 0.0335 0.08
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0178 0.0872
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0072 0.0103
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni opsin-like receptor 0.0023 0.0072 0.028
Entamoeba histolytica acyl-coA synthetase, putative 0.0032 0.0156 0.7035
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0091 0.0091
Brugia malayi putative neuropeptide receptor 0.0023 0.0072 0.0072
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0137 0.3209
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0218 0.6413
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0022 0.0086
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0335 0.1309
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.000000018402 0.000000026451
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0038 0.0208 0.0344
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0091 0.0131
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0039 0.5
Echinococcus granulosus phd:f box containing protein 0.0016 0.0012 0.0028
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0072 0.0103
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0038 0.0208 0.0344
Brugia malayi Tachykinin-like peptides receptor 99D 0.0023 0.0072 0.0072
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi hypothetical protein 0.0163 0.1299 0.1299
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.027 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0318 0.8836
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0409 0.069
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0072 0.0171
Onchocerca volvulus Neuropeptide F receptor homolog 0.0023 0.0072 0.019
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0072 0.0103
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0359 0.0359
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0171 0.0171
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0072 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0053 0.0335 0.0335
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0012 0.0017
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0053 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0335 0.0335
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0178 0.4251
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0072 0.0171
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0072 0.0103
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0053 0.0335 0.0482
Schistosoma mansoni neuropeptide receptor 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.0038 0.0208 0.0208
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0072 0.028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0053 0.0335 0.0335
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0038 0.0208 0.0344
Brugia malayi sulfakinin receptor protein 0.0023 0.0072 0.0072
Leishmania major 4-coumarate:coa ligase-like protein 0.0032 0.0156 0.3702
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0072 0.0103
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0039 0.0039
Echinococcus granulosus hypothetical protein 0.0023 0.0072 0.0171
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0286 0.1115
Echinococcus multilocularis transcription factor btf3 0.0035 0.0178 0.0257
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.004
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0072 0.0171
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0023 0.0072 0.0103
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0038 0.0208 0.0344
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0011
Brugia malayi nuclear receptor NHR-88 0.0025 0.0091 0.0091
Schistosoma mansoni myosin xvIII 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.0448 0.3784 0.3784
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Schistosoma mansoni jumonji domain containing protein 0.006 0.0392 0.1532
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0008 0.0019
Schistosoma mansoni opsin-like receptor 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0012
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0012 0.0017
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0091 0.0091
Brugia malayi jmjC domain containing protein 0.006 0.0392 0.0392
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0032 0.0156 0.0254
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0091 0.0131
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0072 0.0103
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0072 0.0171
Onchocerca volvulus Bile acid receptor homolog 0.0053 0.0335 0.0886
Echinococcus granulosus g protein coupled receptor 0.0023 0.0072 0.0171
Onchocerca volvulus 0.024 0.1966 0.5195
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0008 0.0031
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0218 1
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0012
Echinococcus granulosus neuropeptide receptor 0.0023 0.0072 0.0171
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0091 0.0131
Schistosoma mansoni ran 0.0021 0.0058 0.0228
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0038 0.0208 0.5709
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.0042
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0091 0.0131
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.000000018402 0.000000071823
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0032 0.0156 0.0156
Brugia malayi neuropeptide F receptor 0.0023 0.0072 0.0072
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0072 0.028
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0012 0.0028
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0023 0.0072 0.0103
Schistosoma mansoni nuclear receptor 0.0025 0.0091 0.0355
Echinococcus granulosus g protein coupled receptor 0.0023 0.0072 0.0171
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0028 0.0041
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0039 0.016
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0099 0.2611
Brugia malayi hypothetical protein 0.0243 0.199 0.199
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0008 0.0011
Loa Loa (eye worm) runx1 0.0056 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0099 0.2611
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0409 0.0588
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0523 0.1249
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0077 0.0355
Schistosoma mansoni adenoreceptor 0.0023 0.0072 0.028
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0812 0.6957 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0335 0.0335
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0038 0.0208 0.0344
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0023 0.0072 0.0072
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0091 0.0091
Schistosoma mansoni neuropeptide receptor 0.0023 0.0072 0.028
Onchocerca volvulus 0.0023 0.0072 0.019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0072 0.0103
Onchocerca volvulus 0.0025 0.0091 0.0241
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.007 0.0101
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0039 0.1488
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0072 0.0103
Leishmania major 4-coumarate:coa ligase-like protein 0.0032 0.0156 0.3702
Brugia malayi STAT protein, DNA binding domain containing protein 0.0129 0.0995 0.0995
Brugia malayi hypothetical protein 0.0028 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Onchocerca volvulus 0.0053 0.0335 0.0886
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0058 0.1468
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0072 0.028
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0012
Brugia malayi nuclear hormone receptor 0.0025 0.0091 0.0091
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0125 0.3354
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0137 0.0533
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0011 0.0026
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0012 0.0137
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0072 0.0072
Schistosoma mansoni growth hormone secretagogue receptor 0.0023 0.0072 0.028
Onchocerca volvulus 0.0023 0.0072 0.019
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0127 0.0985 0.2349
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0309 0.0309
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0023 0.0072 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0038 0.0208 0.0344
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0038 0.0208 0.5709
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0409 0.0976
Schistosoma mansoni amine GPCR 0.0023 0.0072 0.028
Echinococcus multilocularis Ankyrin 0.0015 0.0001 0.0002
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0023 0.0072 0.0171
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0072 0.028
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0038 0.0208 0.0344
Onchocerca volvulus 0.0023 0.0072 0.019
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0021 0.0023
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0053 0.0335 0.08
Echinococcus granulosus ecdysone induced protein 78C 0.0053 0.0335 0.08
Loa Loa (eye worm) hypothetical protein 0.0046 0.0277 0.0277
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0058 0.126
Onchocerca volvulus 0.0023 0.0072 0.019
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0099 0.2611
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0032 0.0156 0.739
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0053 0.0335 0.0335
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0392 0.0936
Echinococcus multilocularis allatostatin A receptor 0.0023 0.0072 0.0103
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0117 0.0458
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0072 0.0103
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Echinococcus multilocularis neuropeptide FF receptor 2 0.0023 0.0072 0.0103
Echinococcus multilocularis FTZ F1 alpha 0.0053 0.0335 0.0482
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0072 0.0171
Echinococcus multilocularis somatostatin receptor 0.0023 0.0072 0.0103
Brugia malayi Death domain containing protein 0.0015 0.000000018402 0.000000018402
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0392 0.0564
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0038 0.0208 0.0344
Brugia malayi putative neuropeptide receptor NPR1 0.0023 0.0072 0.0072
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0318 0.0457
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0127 0.0985 0.1415
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0091 0.0355
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0072 0.028
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0039 0.092
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0318 0.8836
Schistosoma mansoni hypothetical protein 0.0308 0.2562 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0023 0.0072 0.0171
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0039 0.0805
Echinococcus granulosus FTZ F1 alpha 0.0053 0.0335 0.08
Echinococcus granulosus allatostatin A receptor 0.0023 0.0072 0.0171
Echinococcus multilocularis sex peptide receptor 0.0023 0.0072 0.0103
Brugia malayi Cytochrome P450 family protein 0.0038 0.0208 0.0208
Brugia malayi hypothetical protein 0.0448 0.3784 0.3784
Echinococcus multilocularis survival motor neuron protein 1 0.0243 0.199 0.2861
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0023 0.0072 0.028
Onchocerca volvulus 0.0023 0.0072 0.019
Loa Loa (eye worm) hypothetical protein 0.0028 0.0117 0.0117
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0072 0.0103
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0099 0.3466
Schistosoma mansoni amine GPCR 0.0023 0.0072 0.028
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0058 0.1929
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0038 0.0208 0.0344
Schistosoma mansoni hypothetical protein 0.0023 0.0072 0.028
Onchocerca volvulus 0.0036 0.0188 0.0496
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0039 0.0054
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0032 0.0156 0.0254
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0039 0.1488
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0058 0.0058
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0099 0.4324
Echinococcus granulosus neuropeptide FF receptor 2 0.0023 0.0072 0.0171
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0072 0.0171
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0091 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0053 0.0335 0.0335
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0038 0.0208 0.0344
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.007 0.0167
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0008 0.0029
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0127 0.0303
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0038 0.0208 0.0344
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0335 0.0335
Schistosoma mansoni coup transcription factor 0.0053 0.0335 0.1309
Brugia malayi Bromodomain containing protein 0.0042 0.0239 0.0239
Brugia malayi Dopamine receptor 0.0023 0.0072 0.0072
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0038 0.0208 0.0344
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0053 0.0335 0.0482
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0032 0.0156 0.0254
Onchocerca volvulus 0.0023 0.0072 0.019
Echinococcus granulosus transcription factor btf3 0.0035 0.0178 0.0426
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0023 0.0072 0.0103
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0409 1
Brugia malayi PHD-finger family protein 0.0029 0.0122 0.0122
Trypanosoma brucei cytochrome P450, putative 0.0056 0.0359 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0023 0.0072 0.0072
Brugia malayi hypothetical protein 0.0025 0.0091 0.0091
Schistosoma mansoni alpha-1 adrenergic receptor 0.0023 0.0072 0.028
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0038 0.0208 0.0344
Brugia malayi follicle stimulating hormone receptor 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0072 0.0103
Onchocerca volvulus 0.0015 0.0008 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0072 0.028
Brugia malayi GnHR receptor homolog 0.0023 0.0072 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0053 0.0335 0.0335
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0091 0.0217
Plasmodium vivax importin-beta 2, putative 0.0029 0.0125 0.4465
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0137 0.0196
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0091 0.0091
Brugia malayi nuclear receptor NHR-67 0.0025 0.0091 0.0091
Brugia malayi G-protein coupled receptor 0.0023 0.0072 0.0072
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0032 0.0156 0.0254
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0053 0.0335 0.0482
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0038 0.0208 0.0344
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0038 0.0208 0.0344
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0012 0.0028
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0077 0.0355
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0022 0.0086
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0359 1
Schistosoma mansoni hypothetical protein 0.0038 0.0208 0.0812
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0409 0.0409
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0012
Loa Loa (eye worm) cytochrome P450 family protein 0.0095 0.07 0.07
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0091 0.0217
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0188 0.0309
Brugia malayi Steroid receptor seven-up type 2 0.0053 0.0335 0.0335
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0038 0.0208 0.0344
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.000000018402 0.000000043907
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0023 0.0072 0.0072
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0091 0.0241
Brugia malayi Cytochrome P450 family protein 0.0056 0.0359 0.0359
Brugia malayi Serotonin receptor 0.0023 0.0072 0.0072
Schistosoma mansoni neuropeptide f receptor 76f 0.0023 0.0072 0.028
Schistosoma mansoni single-minded 0.0049 0.0298 0.1163
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0117 0.0458
Echinococcus granulosus 7TM GPCR rhodopsin 0.0023 0.0072 0.0171
Leishmania major cytochrome p450-like protein 0.0056 0.0359 0.8758
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0318 0.7732
Echinococcus granulosus 7tm_1 domain containing protein 0.0023 0.0072 0.0171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0072 0.028
Echinococcus granulosus cytochrome P450 2K1 0.0038 0.0208 0.0496
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0072 0.0103
Leishmania major cytochrome p450-like protein 0.0038 0.0208 0.5
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0012 0.0176
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0053 0.0335 0.08
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0523 0.0752
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0038 0.0208 0.0344
Echinococcus granulosus peptide allatostatin:somatostatin 0.0023 0.0072 0.0171
Loa Loa (eye worm) hypothetical protein 0.0028 0.0117 0.0117
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0058 0.0692
Echinococcus granulosus alpha 1A adrenergic receptor 0.0023 0.0072 0.0171
Echinococcus granulosus Ankyrin 0.0015 0.0001 0.0003
Echinococcus multilocularis thyroid hormone receptor alpha 0.018 0.1447 0.208
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0038 0.0208 0.0344
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0178 0.0872
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0091 0.0355
Brugia malayi steroid hormone receptor 0.0053 0.0335 0.0335
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0091 0.0217
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.2562 0.2562
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0072 0.0103
Brugia malayi nuclear receptor NHR-88 0.0053 0.0335 0.0335
Echinococcus granulosus dro:myosuppressin receptor 0.0023 0.0072 0.0171
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0038 0.0208 0.0344
Loa Loa (eye worm) hypothetical protein 0.0034 0.0171 0.0171
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0318 0.0759
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0053 0.0335 0.08
Schistosoma mansoni bromodomain containing protein 0.0067 0.0457 0.1785
Brugia malayi Melatonin receptor type 1A 0.0023 0.0072 0.0072
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0012 0.0092
Brugia malayi AKH receptor 0.0023 0.0072 0.0072
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0178 0.8117
Echinococcus multilocularis neuropeptide s receptor 0.0495 0.4191 0.6024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0025 0.0091 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0053 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.1161 1 1
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0218 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0038 0.0208 0.5709
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0072 0.028
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0125 0.2917
Onchocerca volvulus 0.003 0.0137 0.0361
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0038 0.0208 0.0344
Brugia malayi jmjC domain containing protein 0.0016 0.0012 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0072 0.028
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0039 0.016
Mycobacterium ulcerans acyl-CoA synthetase 0.0032 0.0156 0.0254
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0021 0.0023
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0286 0.0681
Entamoeba histolytica acyl-CoA synthetase, putative 0.0032 0.0156 0.7035
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0039 0.1192
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0038 0.0208 0.0344
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0032 0.0156 0.739
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0053 0.0335 0.1309
Loa Loa (eye worm) cytochrome P450 0.0038 0.0208 0.0208
Echinococcus granulosus neuropeptide receptor 0.0023 0.0072 0.0171
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0008 0.0033
Loa Loa (eye worm) hypothetical protein 0.0028 0.0117 0.0117
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0072 0.0103
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) oxidoreductase 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypoxia-induced factor 1 0.0151 0.1188 0.1188
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0077 0.0355
Loa Loa (eye worm) steroid hormone receptor 0.0053 0.0335 0.0335
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0012 0.0045
Loa Loa (eye worm) hypothetical protein 0.0053 0.0335 0.0335
Loa Loa (eye worm) melatonin receptor type 1A 0.0023 0.0072 0.0072
Brugia malayi AMP-binding enzyme family protein 0.0032 0.0156 0.0156
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0072 0.0171
Schistosoma mansoni retinoic acid receptor RXR 0.0053 0.0335 0.1309
Schistosoma mansoni lozenge 0.0056 0.0364 0.1419
Brugia malayi hypothetical protein 0.0025 0.0091 0.0091
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0091 0.0217
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0053 0.0335 0.0335
Echinococcus multilocularis g-protein coupled receptor 0.0023 0.0072 0.0103
Brugia malayi hypothetical protein 0.0017 0.0019 0.0019
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0053 0.0335 0.08
Echinococcus granulosus G protein coupled receptor 139 0.0023 0.0072 0.0171
Schistosoma mansoni hypothetical protein 0.0023 0.0072 0.028
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0309 0.0309
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.1174 0.1174
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0187 0.0269
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0038 0.0208 0.0344
Schistosoma mansoni zinc finger protein 0.0025 0.0091 0.0355
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0038 0.0208 0.0344
Schistosoma mansoni thyroid hormone receptor 0.018 0.1447 0.5647
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0023 0.0072 0.019
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0309 0.0309
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0053 0.0335 0.0335
Brugia malayi ecdysone receptor 0.0025 0.0091 0.0091
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0072 0.028
Brugia malayi MAP kinase sur-1 0.0051 0.0318 0.0318
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0682 0.5823 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi Importin beta-1 subunit 0.0029 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0318 0.7738
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Leishmania major hypothetical protein, conserved 0.0016 0.0012 0.012
Schistosoma mansoni nuclear receptor 0.0025 0.0091 0.0355
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0023 0.0072 0.028
Loa Loa (eye worm) hypothetical protein 0.005 0.0309 0.0309
Schistosoma mansoni hypothetical protein 0.0034 0.0171 0.0666
Echinococcus multilocularis Protein lozenge 0.0056 0.0364 0.0523
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0178 0.4873
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0409 0.069
Loa Loa (eye worm) CYP4Cod1 0.0056 0.0359 0.0359
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0053 0.0335 0.0335
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0058 0.0139
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0008 0.0008
Onchocerca volvulus 0.0025 0.0091 0.0241
Echinococcus multilocularis 0.0038 0.0208 0.0299
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0072 0.028
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0318 0.1242
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0039 0.0093
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0012 0.0137
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0053 0.0335 0.0335
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.004
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0072 0.0103
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0286 0.0411
Echinococcus granulosus snurportin 1 0.0308 0.2562 0.6113
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.004 0.1213
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0426 0.0612
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.027 0.134
Plasmodium vivax JmjC domain containing protein 0.0016 0.0012 0.0141
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0012 0.0045
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0056 0.0359 0.0604
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0011 0.0011
Echinococcus multilocularis neuropeptide receptor A26 0.0495 0.4191 0.6024
Loa Loa (eye worm) TYRA-2 protein 0.0023 0.0072 0.0072
Onchocerca volvulus 0.0023 0.0072 0.019
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0318 0.1586
Brugia malayi Pre-SET motif family protein 0.0211 0.1711 0.1711
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0448 0.3784 0.3784
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0008 0.0029
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0359 0.0359
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.004 0.5
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0318 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 67.22 uM Inhibition of MAOA in rat liver homogenates preincubated for 60 mins ChEMBL. 18980841
IC50 (binding) = 400.05 uM Inhibition of MAOB in rat liver homogenates preincubated for 60 mins ChEMBL. 18980841

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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