Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0009 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0009 | 0.003 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0253 | 0.1017 | 0.3308 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0067 | 0.0215 | 0.0673 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0025 | 0.0032 | 0.0054 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.0243 | 0.0764 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0067 | 0.0215 | 0.0673 |
Echinococcus multilocularis | glutamate synthase | 0.0067 | 0.0215 | 0.0362 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0019 | 0.0009 | 0.003 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0067 | 0.0215 | 0.0701 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0067 | 0.0215 | 0.0701 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0067 | 0.0215 | 0.0701 |
Onchocerca volvulus | 0.0019 | 0.0009 | 0.0114 | |
Plasmodium falciparum | glutathione reductase | 0.0731 | 0.3073 | 1 |
Brugia malayi | glutathione reductase | 0.0731 | 0.3073 | 1 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0067 | 0.0215 | 0.0362 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0253 | 0.1017 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0243 | 0.0097 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0215 | 0.0215 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0253 | 0.1017 | 0.2803 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0067 | 0.0215 | 0.0673 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0253 | 0.1017 | 0.3288 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0253 | 0.1017 | 0.3288 |
Plasmodium vivax | vivapain-2 | 0.0019 | 0.0009 | 0.003 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0067 | 0.0215 | 0.0673 |
Onchocerca volvulus | 0.0019 | 0.0009 | 0.0114 | |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0067 | 0.0215 | 0.0362 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.0067 | 0.0215 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0009 | 0.003 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0253 | 0.1017 | 0.3308 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0253 | 0.1017 | 0.3288 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0253 | 0.1017 | 1 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0067 | 0.0215 | 0.0673 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0058 | 0.0175 | 0.0542 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0025 | 0.0032 | 0.0104 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0032 | 0.0032 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0215 | 0.0673 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0025 | 0.0032 | 0.0054 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0019 | 0.0009 | 0.0016 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Schistosoma mansoni | smad | 0.0025 | 0.0032 | 0.0032 |
Entamoeba histolytica | thioredoxin reductase, putative | 0.0067 | 0.0215 | 1 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0067 | 0.0215 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Toxoplasma gondii | thioredoxin reductase | 0.0731 | 0.3073 | 1 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0067 | 0.0215 | 0.0362 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0253 | 0.1017 | 0.3308 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0067 | 0.0215 | 0.0701 |
Loa Loa (eye worm) | fibroinase | 0.0019 | 0.0009 | 0.003 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0067 | 0.0215 | 0.212 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0253 | 0.1017 | 0.1709 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0253 | 0.1017 | 0.3288 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Schistosoma mansoni | glutamate synthase | 0.0067 | 0.0215 | 0.0215 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0067 | 0.0215 | 0.0673 |
Mycobacterium tuberculosis | Probable reductase | 0.1667 | 0.7105 | 0.8958 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.1853 | 0.7907 | 1 |
Onchocerca volvulus | 0.0019 | 0.0009 | 0.0114 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0019 | 0.0009 | 0.003 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.0243 | 0.0764 |
Echinococcus multilocularis | Smad4 | 0.0025 | 0.0032 | 0.0054 |
Entamoeba histolytica | disulphide oxidoreductase, putative | 0.0067 | 0.0215 | 1 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0067 | 0.0215 | 0.0362 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0019 | 0.0009 | 0.003 |
Plasmodium falciparum | thioredoxin reductase | 0.0731 | 0.3073 | 1 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0067 | 0.0215 | 0.0362 |
Loa Loa (eye worm) | cysteine protease | 0.0019 | 0.0009 | 0.003 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0253 | 0.1017 | 1 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0067 | 0.0215 | 0.0673 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0067 | 0.0215 | 0.212 |
Onchocerca volvulus | Cathepsin F homolog | 0.0019 | 0.0009 | 0.0114 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0253 | 0.1017 | 0.3288 |
Onchocerca volvulus | 0.0019 | 0.0009 | 0.0114 | |
Echinococcus granulosus | Smad4 | 0.0025 | 0.0032 | 0.0054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0739 | 0.311 | 0.5227 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0025 | 0.0032 | 0.0032 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0253 | 0.1017 | 0.2803 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0215 | 0.0701 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.0243 | 0.0764 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0215 | 0.212 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0067 | 0.0215 | 0.0362 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0253 | 0.1017 | 1 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0253 | 0.1017 | 0.3288 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0025 | 0.0032 | 0.0054 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0236 | 0.0236 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0731 | 0.3073 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0009 | 0.0016 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0253 | 0.1017 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0236 | 0.0236 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.0009 | 0.0114 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0215 | 0.212 |
Plasmodium vivax | glutathione reductase, putative | 0.0731 | 0.3073 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0009 | 0.003 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0009 | 0.0016 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0067 | 0.0215 | 0.0701 |
Loa Loa (eye worm) | RNA binding protein | 0.0072 | 0.0236 | 0.0768 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0253 | 0.1017 | 0.1042 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0236 | 0.0236 |
Schistosoma mansoni | glutamate synthase | 0.0067 | 0.0215 | 0.0215 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0025 | 0.0032 | 0.0054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0067 | 0.0215 | 0.0701 |
Onchocerca volvulus | 0.0019 | 0.0009 | 0.0114 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.0243 | 0.0764 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0067 | 0.0215 | 0.0362 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0009 | 0.0016 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0067 | 0.0215 | 0.212 |
Brugia malayi | RNA binding protein | 0.0072 | 0.0236 | 0.0768 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.1853 | 0.7907 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0205 | 0.0808 | 0.0808 |
Echinococcus granulosus | smad | 0.0025 | 0.0032 | 0.0054 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0067 | 0.0215 | 0.0362 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.0067 | 0.0215 | 0.0701 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0253 | 0.1017 | 0.3288 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0253 | 0.1017 | 0.3308 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0067 | 0.0215 | 0.0362 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0253 | 0.1017 | 0.2803 |
Toxoplasma gondii | selenide, water dikinase | 0.0067 | 0.0215 | 0.0701 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0253 | 0.1017 | 0.3288 |
Echinococcus granulosus | tar DNA binding protein | 0.0072 | 0.0236 | 0.0396 |
Echinococcus granulosus | cathepsin l1 | 0.0019 | 0.0009 | 0.0016 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0032 | 0.0104 |
Treponema pallidum | NADH oxidase | 0.0253 | 0.1017 | 1 |
Leishmania major | cathepsin L-like protease | 0.0074 | 0.0243 | 0.0764 |
Echinococcus granulosus | glutamate synthase | 0.0067 | 0.0215 | 0.0362 |
Brugia malayi | MH2 domain containing protein | 0.0361 | 0.148 | 0.4817 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0009 | 0.0009 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0215 | 0.0673 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0067 | 0.0215 | 0.0362 |
Onchocerca volvulus | 0.0019 | 0.0009 | 0.0114 | |
Loa Loa (eye worm) | Smad1 | 0.0025 | 0.0032 | 0.0104 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0032 | 0.0104 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0067 | 0.0215 | 0.0673 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0032 | 0.0104 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0009 | 0.003 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0067 | 0.0215 | 0.0673 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0067 | 0.0215 | 0.0673 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0253 | 0.1017 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.0808 | 0.2628 |
Echinococcus granulosus | tumor protein p63 | 0.1399 | 0.595 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0019 | 0.0009 | 0.0016 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0009 | 0.0016 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Schistosoma mansoni | Smad4 | 0.0025 | 0.0032 | 0.0032 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0253 | 0.1017 | 0.3308 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0253 | 0.1017 | 0.1017 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0009 | 0.003 |
Onchocerca volvulus | 0.0067 | 0.0215 | 0.2668 | |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0428 | 0.1769 | 0.1769 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0253 | 0.1017 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0243 | 0.0097 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Plasmodium falciparum | glutathione reductase | 0.0253 | 0.1017 | 0.3308 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0243 | 0.0097 |
Trypanosoma brucei | trypanothione reductase | 0.0731 | 0.3073 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.1853 | 0.7907 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.1667 | 0.7105 | 0.8958 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0019 | 0.0009 | 0.003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0243 | 0.0097 |
Loa Loa (eye worm) | glutathione reductase | 0.0731 | 0.3073 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0253 | 0.1017 | 0.3288 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0067 | 0.0215 | 0.212 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0739 | 0.311 | 0.5227 |
Echinococcus multilocularis | tumor protein p63 | 0.1399 | 0.595 | 1 |
Onchocerca volvulus | 0.0019 | 0.0009 | 0.0114 | |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.1667 | 0.7105 | 0.8958 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0253 | 0.1017 | 0.3288 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0253 | 0.1017 | 0.3308 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0067 | 0.0215 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0243 | 0.0097 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0032 | 0.0032 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0067 | 0.0215 | 0.0701 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0009 | 0.003 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0072 | 0.0236 | 0.0768 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0253 | 0.1017 | 0.3288 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0019 | 0.0009 | 0.003 |
Leishmania major | NADH dehydrogenase, putative | 0.0067 | 0.0215 | 0.0673 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0731 | 0.3073 | 0.3716 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0067 | 0.0215 | 0.212 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0361 | 0.148 | 0.4817 |
Toxoplasma gondii | cathepsin CPL | 0.0019 | 0.0009 | 0.003 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0731 | 0.3073 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0253 | 0.1017 | 0.1709 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Loa Loa (eye worm) | ctsf protein | 0.0019 | 0.0009 | 0.003 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0186 | 0.0727 | 0.2366 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0072 | 0.0236 | 0.0768 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.0067 | 0.0215 | 0.0701 |
Schistosoma mansoni | sulfide quinone reductase | 0.0067 | 0.0215 | 0.0215 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.1667 | 0.7105 | 0.8958 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0019 | 0.0009 | 0.003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0243 | 0.0097 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0243 | 0.0097 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.1667 | 0.7105 | 0.8958 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.1667 | 0.7105 | 0.8958 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Echinococcus multilocularis | smad | 0.0025 | 0.0032 | 0.0054 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0032 | 0.0104 |
Onchocerca volvulus | 0.0205 | 0.0808 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0067 | 0.0215 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0731 | 0.3073 | 1 |
Schistosoma mansoni | glutamate synthase | 0.0067 | 0.0215 | 0.0215 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0215 | 0.212 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0067 | 0.0215 | 0.212 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.0067 | 0.0215 | 0.0701 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0025 | 0.0032 | 0.0104 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0361 | 0.148 | 0.4817 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0067 | 0.0215 | 0.212 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0009 | 0.003 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0215 | 0.212 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0067 | 0.0215 | 0.0701 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0253 | 0.1017 | 0.3288 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0067 | 0.0215 | 0.0362 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0236 | 0.0236 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0253 | 0.1017 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0067 | 0.0215 | 0.0701 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0243 | 0.0097 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0186 | 0.0727 | 0.2366 |
Schistosoma mansoni | sulfide quinone reductase | 0.0067 | 0.0215 | 0.0215 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0067 | 0.0215 | 0.0701 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0067 | 0.0215 | 0.0701 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0009 | 0.0009 |
Plasmodium falciparum | thioredoxin reductase | 0.0253 | 0.1017 | 0.3308 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.1853 | 0.7907 | 1 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0067 | 0.0215 | 0.0215 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0253 | 0.1017 | 0.2803 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0243 | 0.0097 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0236 | 0.0236 |
Brugia malayi | TAR-binding protein | 0.0072 | 0.0236 | 0.0768 |
Echinococcus multilocularis | tar DNA binding protein | 0.0072 | 0.0236 | 0.0396 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0074 | 0.0243 | 0.0764 |
Entamoeba histolytica | pyridine nucleotide-disulfide oxidoreductase family protein | 0.0067 | 0.0215 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0243 | 0.0097 |
Brugia malayi | glutamate synthase | 0.0067 | 0.0215 | 0.0701 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0074 | 0.0243 | 0.0764 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Leishmania major | trypanothione reductase | 0.0731 | 0.3073 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0731 | 0.3073 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0215 | 0.0673 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0074 | 0.0243 | 0.0097 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0067 | 0.0215 | 0.0701 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0009 | 0.0091 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.0009 | 0.0114 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0253 | 0.1017 | 0.3308 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0215 | 0.212 |
Loa Loa (eye worm) | TAR-binding protein | 0.0072 | 0.0236 | 0.0768 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0067 | 0.0215 | 0.0673 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0215 | 0.212 |
Plasmodium vivax | vivapain-2 | 0.0019 | 0.0009 | 0.003 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.1667 | 0.7105 | 0.8958 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0067 | 0.0215 | 0.0362 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0253 | 0.1017 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0067 | 0.0216 | 0.0674 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0009 | 0.0016 |
Brugia malayi | Smad1 | 0.0025 | 0.0032 | 0.0104 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0067 | 0.0215 | 0.0701 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0253 | 0.1017 | 0.3288 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.