Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0045 | 0.0528 | 0.0482 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0528 | 0.0482 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0237 | 0.8618 | 0.8679 |
Echinococcus granulosus | geminin | 0.0193 | 0.676 | 0.6814 |
Echinococcus granulosus | neuroligin | 0.0045 | 0.0528 | 0.0532 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.1787 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.014 | 0.4523 | 0.453 |
Echinococcus multilocularis | jun protein | 0.0085 | 0.2216 | 0.2192 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0528 | 0.0482 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0528 | 0.0482 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0268 | 0.9922 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.014 | 0.4523 | 0.453 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.9922 | 1 |
Brugia malayi | bZIP transcription factor family protein | 0.0085 | 0.2216 | 0.2192 |
Loa Loa (eye worm) | carboxylesterase | 0.0045 | 0.0528 | 0.0482 |
Echinococcus multilocularis | acetylcholinesterase | 0.0268 | 0.9922 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0268 | 0.9922 | 1 |
Onchocerca volvulus | 0.0045 | 0.0528 | 0.0478 | |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0528 | 0.0482 |
Brugia malayi | Carboxylesterase family protein | 0.0268 | 0.9922 | 1 |
Echinococcus multilocularis | neuroligin | 0.0045 | 0.0528 | 0.0482 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0045 | 0.0528 | 0.5 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0053 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.014 | 0.4523 | 0.453 |
Onchocerca volvulus | 0.0067 | 0.1444 | 0.1398 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.0268 | 0.9922 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0237 | 0.8618 | 0.8679 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0045 | 0.0528 | 0.0482 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0075 | 0.1787 | 0.1801 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0045 | 0.0528 | 0.0482 |
Schistosoma mansoni | acetylcholinesterase | 0.0045 | 0.0528 | 0.0482 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0528 | 0.0482 |
Echinococcus granulosus | acetylcholinesterase | 0.0268 | 0.9922 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0268 | 0.9922 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0528 | 0.0482 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0528 | 0.0482 |
Loa Loa (eye worm) | carboxylesterase | 0.0268 | 0.9922 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.1787 | 0.5 |
Brugia malayi | hypothetical protein | 0.0067 | 0.1444 | 0.1409 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0075 | 0.1787 | 0.1757 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.676 | 0.6797 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.9922 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.0528 | 0.0482 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0085 | 0.2216 | 0.2234 |
Echinococcus granulosus | jun protein | 0.0085 | 0.2216 | 0.2234 |
Onchocerca volvulus | 0.0045 | 0.0528 | 0.0478 | |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0528 | 0.0482 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0053 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0045 | 0.0528 | 0.5 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0045 | 0.0528 | 0.0482 |
Onchocerca volvulus | 0.0045 | 0.0528 | 0.0478 | |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.2118 | 0.2092 |
Echinococcus multilocularis | acetylcholinesterase | 0.0268 | 0.9922 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.1787 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0045 | 0.0528 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0528 | 0.0482 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0045 | 0.0528 | 0.0532 |
Schistosoma mansoni | gliotactin | 0.0045 | 0.0528 | 0.0482 |
Loa Loa (eye worm) | carboxylesterase | 0.0045 | 0.0528 | 0.0482 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0034 | 0.0053 | 0.0053 |
Brugia malayi | Carboxylesterase family protein | 0.0045 | 0.0528 | 0.0482 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.0528 | 0.0482 |
Onchocerca volvulus | 0.0045 | 0.0528 | 0.0478 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0085 | 0.2216 | 0.2192 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0045 | 0.0528 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0059 | 0.1103 | 0.1065 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0528 | 0.0482 |
Brugia malayi | Carboxylesterase family protein | 0.0268 | 0.9922 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0268 | 0.9922 | 1 |
Brugia malayi | hypothetical protein | 0.0075 | 0.1787 | 0.1757 |
Onchocerca volvulus | 0.0045 | 0.0528 | 0.0478 | |
Schistosoma mansoni | jun-related protein | 0.0069 | 0.1542 | 0.1509 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0045 | 0.0528 | 0.0532 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0075 | 0.1787 | 0.1757 |
Trichomonas vaginalis | set domain proteins, putative | 0.027 | 1 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0045 | 0.0528 | 0.0482 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.676 | 0.6797 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0045 | 0.0528 | 0.0482 |
Schistosoma mansoni | hypothetical protein | 0.0075 | 0.1787 | 0.1757 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.1542 | 0.1509 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.1787 | 0.5 |
Echinococcus multilocularis | geminin | 0.0193 | 0.676 | 0.6797 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0045 | 0.0528 | 0.0532 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0045 | 0.0528 | 0.0482 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.