Detailed information for compound 1012263

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 426.462 | Formula: C23H26N2O6
  • H donors: 2 H acceptors: 4 LogP: 1.42 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)N1c2ccccc2[C@@]23[C@]41CC[C@@]1([C@@H]([C@]4(O)C(=O)OC)O)[C@H]3N(CC2)CC=C1
  • InChi: 1S/C23H26N2O6/c1-30-18(27)23(29)17(26)20-8-5-12-24-13-11-21(16(20)24)14-6-3-4-7-15(14)25(19(28)31-2)22(21,23)10-9-20/h3-8,16-17,26,29H,9-13H2,1-2H3/t16-,17+,20-,21+,22-,23+/m1/s1
  • InChiKey: HVUPNDMRYTUMME-JLCSSFLSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0078 0.0175
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.1629 0.2039
Loa Loa (eye worm) cysteine protease 0.002 0.0042 0.0053
Loa Loa (eye worm) hypothetical protein 0.004 0.0298 0.0373
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0799 0.1787
Schistosoma mansoni tyrosinase precursor 0.0097 0.1059 0.1326
Entamoeba histolytica diacylglycerol kinase, putative 0.0045 0.0368 0.0736
Echinococcus multilocularis Rac GTPase activating protein 1 0.0045 0.0368 0.0368
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0147 0.0328
Mycobacterium ulcerans peptide amidase, GatA 0.0075 0.0764 0.103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0799 0.1787
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0097 0.1059 0.1326
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0097 0.1059 0.1326
Schistosoma mansoni fatty-acid amide hydrolase 0.0621 0.7991 1
Leishmania major hypothetical protein, conserved 0.0021 0.005 0.0111
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.1546 0.1934
Toxoplasma gondii protein c14orf29, putative 0.0021 0.005 0.0807
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0615 0.077
Brugia malayi MGC79044 protein 0.0021 0.005 0.0062
Loa Loa (eye worm) hypothetical protein 0.0045 0.0368 0.0461
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0355 0.4473 1
Echinococcus multilocularis protein kinase c epsilon type 0.0184 0.2204 0.2204
Schistosoma mansoni atypical protein kinase C 0.0109 0.1211 0.1516
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.0298 0.0373
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0147 0.0328
Echinococcus multilocularis unc 13 (munc13) 0.0051 0.0451 0.0451
Brugia malayi RhoGAP domain containing protein 0.0045 0.0368 0.0461
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0062 0.0597 0.1253
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0053
Plasmodium vivax unspecified product 0.0021 0.005 0.0111
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0298 0.0373
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.0298 0.0298
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.0298 0.0373
Echinococcus granulosus Rac GTPase activating protein 1 0.0045 0.0368 0.0368
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0021 0.005 0.0017
Brugia malayi hypothetical protein 0.0035 0.0234 0.0292
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0078 0.0078
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0053
Plasmodium falciparum exported lipase 1 0.0021 0.005 0.0111
Brugia malayi Protein kinase domain containing protein 0.0064 0.0615 0.077
Plasmodium vivax PST-A protein 0.0021 0.005 0.0111
Plasmodium vivax PST-A protein 0.0355 0.4473 1
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0298 0.0577
Loa Loa (eye worm) hypothetical protein 0.0045 0.0368 0.0461
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0316 0.0395
Entamoeba histolytica protein kinase, putative 0.0064 0.0615 0.1294
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0046 0.0387 0.0387
Onchocerca volvulus 0.0097 0.1059 0.3017
Leishmania major cysteine peptidase A (CPA) 0.002 0.0042 0.0094
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0021 0.005 0.0111
Plasmodium vivax vivapain-2 0.002 0.0042 0.0094
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0078 0.0098
Plasmodium falciparum lysophospholipase, putative 0.0355 0.4473 1
Plasmodium vivax lysophospholipase, putative 0.0021 0.005 0.0111
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0045 0.0368 0.0461
Toxoplasma gondii diacylglycerol kinase, putative 0.0045 0.0368 0.5987
Schistosoma mansoni regulator of G protein signaling 0.004 0.0298 0.0373
Trypanosoma cruzi cysteine peptidase, putative 0.0078 0.0799 0.1787
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.005 0.0071
Plasmodium vivax unspecified product 0.0021 0.005 0.0111
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0041 0.0316 0.0395
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0064 0.0615 0.0615
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0042 0.0094
Echinococcus granulosus monoacylglycerol lipase abhd12 0.0021 0.005 0.005
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0075 0.0764 0.1094
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.005 0.0017
Loa Loa (eye worm) hypothetical protein 0.0045 0.0368 0.0461
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.1629 0.2039
Schistosoma mansoni importin beta-1 0.0031 0.0188 0.0235
Echinococcus granulosus protein kinase C gamma type 0.0226 0.2764 0.2764
Echinococcus granulosus Protein kinase C brain isozyme 0.0271 0.336 0.336
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0298 0.0298
Echinococcus granulosus RNA directed DNA polymerase 0.0156 0.1839 0.1839
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0042 0.0094
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0234 0.0234
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0355 0.4473 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0368 0.0461
Entamoeba histolytica hypothetical protein 0.0035 0.0234 0.0432
Trichomonas vaginalis ran, putative 0.0023 0.0078 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0615 0.1294
Brugia malayi hypothetical protein 0.0066 0.0642 0.0804
Loa Loa (eye worm) hypothetical protein 0.0339 0.4257 0.5327
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0615 0.1294
Entamoeba histolytica hypothetical protein 0.0035 0.0234 0.0432
Brugia malayi protein kinase C3,putative 0.0046 0.0387 0.0484
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0046 0.0387 0.0484
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.1629 0.1629
Entamoeba histolytica hypothetical protein 0.0035 0.0234 0.0432
Echinococcus multilocularis serine:threonine protein kinase 38 0.0064 0.0615 0.0615
Echinococcus multilocularis N chimaerin 0.0045 0.0368 0.0368
Brugia malayi ShTK domain containing protein 0.0097 0.1059 0.1326
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0075 0.0764 0.1708
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0042 0.0053
Loa Loa (eye worm) hypothetical protein 0.0045 0.0368 0.0461
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0147 0.0328
Echinococcus multilocularis raf serine:threonine protein kinase 0.0045 0.0368 0.0368
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0621 0.7991 0.7991
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0424 0.053
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.005 0.0017
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0021 0.005 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0355 0.4473 1
Brugia malayi putative amidase 0.0075 0.0764 0.0956
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.0298 0.0373
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0075 0.0764 0.5
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0083 0.0104
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0615 0.1294
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0298 0.0577
Toxoplasma gondii t-complex protein beta subunit 0.0023 0.0083 0.1345
Schistosoma mansoni unc-13 (munc13) 0.0051 0.0451 0.0564
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0046 0.0387 0.0484
Plasmodium vivax alpha/beta hydrolase, putative 0.0021 0.005 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0799 0.1787
Mycobacterium ulcerans amidase 0.0075 0.0764 0.103
Leishmania major T-complex protein 1, beta subunit, putative 0.0023 0.0083 0.0185
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0799 0.1787
Leishmania major cathepsin L-like protease 0.0078 0.0799 0.1787
Brugia malayi T-complex protein 1, beta subunit 0.0023 0.0083 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0799 0.1787
Trypanosoma cruzi Serine peptidase, Clan SC, Family S09X, putative 0.0021 0.005 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0615 0.077
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0615 0.1294
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0298 0.0577
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0078 0.0175
Entamoeba histolytica Ran family GTPase 0.0023 0.0078 0.0081
Onchocerca volvulus 0.0097 0.1059 0.3017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0799 0.1787
Entamoeba histolytica hypothetical protein 0.004 0.0298 0.0577
Schistosoma mansoni axis inhibition protein axin 0.004 0.0298 0.0373
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0078 0.1269
Toxoplasma gondii hypothetical protein 0.0021 0.005 0.0807
Toxoplasma gondii hypothetical protein 0.0021 0.005 0.0807
Brugia malayi hypothetical protein 0.0028 0.0147 0.0184
Loa Loa (eye worm) hypothetical protein 0.0051 0.0451 0.0564
Leishmania major cathepsin L-like protease 0.002 0.0042 0.0094
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0075 0.0764 0.1094
Mycobacterium ulcerans lysophospholipase 0.0355 0.4473 0.638
Schistosoma mansoni regulator of G protein signaling 0.004 0.0298 0.0373
Echinococcus granulosus fatty acid amide hydrolase 1 0.0621 0.7991 0.7991
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0147 0.0328
Trypanosoma cruzi cruzipain precursor, putative 0.0078 0.0799 0.1787
Brugia malayi Protein kinase c protein 2 0.0209 0.2535 0.3173
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0387 0.0484
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0615 0.077
Brugia malayi amidase 0.0621 0.7991 1
Mycobacterium ulcerans amidase 0.0075 0.0764 0.103
Plasmodium falciparum esterase, putative 0.0021 0.005 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0387 0.0484
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0023 0.0083 0.0185
Wolbachia endosymbiont of Brugia malayi aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0075 0.0764 0.5
Echinococcus granulosus importin subunit beta 1 0.0031 0.0188 0.0188
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0147 0.0328
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.1629 0.2039
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0083 0.0104
Loa Loa (eye worm) hypothetical protein 0.0275 0.3414 0.4272
Loa Loa (eye worm) hypothetical protein 0.0021 0.005 0.0062
Echinococcus granulosus fatty acid amide hydrolase 1 0.0075 0.0764 0.0764
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0064 0.0615 0.077
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0298 0.0577
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0064 0.0615 0.077
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0075 0.0764 0.103
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0084 0.088 0.088
Echinococcus granulosus Diacylglycerol kinase theta 0.0045 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0275 0.3414 0.4272
Loa Loa (eye worm) hypothetical protein 0.0045 0.0368 0.0461
Plasmodium falciparum alpha/beta hydrolase, putative 0.0021 0.005 0.0111
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0045 0.0368 0.0368
Loa Loa (eye worm) AGC/NDR protein kinase 0.0064 0.0615 0.077
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.005 0.0017
Plasmodium vivax alpha/beta hydrolase, putative 0.0021 0.005 0.0111
Echinococcus granulosus protein kinase c eta type 0.0045 0.0368 0.0368
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0298 0.0373
Schistosoma mansoni ran 0.0023 0.0078 0.0098
Toxoplasma gondii hypothetical protein 0.0021 0.005 0.0807
Onchocerca volvulus 0.0066 0.0642 0.1781
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0799 0.1787
Schistosoma mansoni jun-related protein 0.0068 0.0673 0.0842
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0075 0.0764 1
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0075 0.0764 0.0764
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0615 0.1294
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0042 0.0094
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0045 0.0368 0.0461
Loa Loa (eye worm) hypothetical protein 0.0576 0.7393 0.9251
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0053
Entamoeba histolytica hypothetical protein 0.004 0.0298 0.0577
Plasmodium falciparum lysophospholipase, putative 0.0021 0.005 0.0111
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0078 0.0175
Echinococcus multilocularis protein kinase c iota type 0.0109 0.1211 0.1211
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0053
Schistosoma mansoni peptidase 0.0021 0.005 0.0062
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0023 0.0083 0.0185
Brugia malayi bZIP transcription factor family protein 0.0084 0.088 0.1102
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.1629 0.1629
Brugia malayi PXA domain containing protein 0.004 0.0298 0.0373
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0097 0.1059 0.1326
Plasmodium falciparum alpha/beta-hydrolase, putative 0.0021 0.005 0.0111
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.004 0.0298 0.0577
Plasmodium falciparum lysophospholipase, putative 0.0355 0.4473 1
Entamoeba histolytica hypothetical protein 0.0045 0.0368 0.0736
Loa Loa (eye worm) hypothetical protein 0.0021 0.005 0.0062
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0147 0.0328
Toxoplasma gondii phospholipase/carboxylesterase 0.0021 0.005 0.0807
Loa Loa (eye worm) ctsf protein 0.002 0.0042 0.0053
Trypanosoma cruzi serine peptidase, putative 0.0021 0.005 0.0111
Brugia malayi T-complex protein 1, beta subunit 0.0023 0.0083 0.0104
Onchocerca volvulus 0.0275 0.3414 1
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0075 0.0764 0.1094
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0298 0.0373
Echinococcus multilocularis RNA directed DNA polymerase 0.0156 0.1839 0.1839
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0355 0.4473 1
Schistosoma mansoni ran 0.0023 0.0078 0.0098
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0064 0.0615 0.077
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0021 0.005 0.0807
Brugia malayi Cytochrome P450 family protein 0.0049 0.0424 0.053
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0156 0.1839 0.1839
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0078 0.0098
Plasmodium falciparum alpha/beta hydrolase, putative 0.0021 0.005 0.0111
Echinococcus granulosus jun protein 0.0084 0.088 0.088
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0075 0.0764 0.1094
Loa Loa (eye worm) RasGEF domain-containing protein 0.0045 0.0368 0.0461
Onchocerca volvulus 0.0045 0.0368 0.0968
Brugia malayi Amidase family protein 0.0075 0.0764 0.0956
Schistosoma mansoni protein kinase C mu 0.0045 0.0368 0.0461
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0021 0.005 0.0111
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0042 0.0042
Echinococcus multilocularis protein kinase c eta type 0.0045 0.0368 0.0368
Schistosoma mansoni hypothetical protein 0.0335 0.4204 0.5261
Plasmodium vivax PST-A protein 0.0021 0.005 0.0111
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.0298 0.0298
Brugia malayi hypothetical protein 0.004 0.0298 0.0373
Leishmania major hypothetical protein, conserved 0.0075 0.0764 0.1708
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0078 0.0175
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0799 0.1787
Toxoplasma gondii phospholipase 0.0021 0.005 0.0807
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0045 0.0368 0.0368
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0298 0.0577
Loa Loa (eye worm) ShTK domain-containing protein 0.0097 0.1059 0.1326
Echinococcus granulosus raf serine:threonine protein kinase 0.0045 0.0368 0.0368
Schistosoma mansoni axis inhibition protein axin 0.004 0.0298 0.0373
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0045 0.0368 0.0461
Echinococcus multilocularis Phospholipase carboxylesterase 0.0021 0.005 0.005
Plasmodium falciparum epoxide hydrolase 2 0.0021 0.005 0.0111
Loa Loa (eye worm) amidase 0.0075 0.0764 0.0956
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0075 0.0764 0.1708
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0083 0.0104
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0075 0.0764 0.0764
Loa Loa (eye worm) tyrosinase 1 0.0097 0.1059 0.1326
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0023 0.0083 0.0083
Brugia malayi RNA, U transporter 1 0.0089 0.0953 0.1193
Loa Loa (eye worm) hypothetical protein 0.0097 0.1059 0.1326
Schistosoma mansoni tyrosinase precursor 0.0097 0.1059 0.1326
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0064 0.0615 0.0615
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0064 0.0615 0.077
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0078 0.0078
Loa Loa (eye worm) fibroinase 0.002 0.0042 0.0053
Schistosoma mansoni protein kinase C mu 0.0046 0.0387 0.0484
Brugia malayi RhoGAP domain containing protein 0.0045 0.0368 0.0461
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.005 0.0017
Echinococcus granulosus abhydrolase domain containing 3 0.0021 0.005 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0368 0.0461
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0298 0.0298
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0621 0.7991 0.7991
Brugia malayi diacylglycerol kinase 0.0045 0.0368 0.0461
Plasmodium vivax lysophospholipase, putative 0.0021 0.005 0.0111
Plasmodium falciparum BEM46-like protein, putative 0.0021 0.005 0.0111
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0298 0.0298
Mycobacterium ulcerans amidase 0.0075 0.0764 0.103
Leishmania major Bem46-like serine peptidase,Serine peptidase, Clan SC, Family S09X 0.0021 0.005 0.0111
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0042 0.0042
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0188 0.042
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0042 0.0042
Trypanosoma brucei monoglyceride lipase, putative 0.0355 0.4473 1
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0075 0.0764 0.0956
Trichomonas vaginalis chaperonin, putative 0.0023 0.0083 0.0092
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0615 0.1294
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0021 0.005 0.0017
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0064 0.0615 0.0615
Leishmania major cathepsin L-like protease 0.0078 0.0799 0.1787
Loa Loa (eye worm) hypothetical protein 0.0021 0.005 0.0062
Loa Loa (eye worm) hypothetical protein 0.004 0.0298 0.0373
Loa Loa (eye worm) AGC/PKN protein kinase 0.0064 0.0615 0.077
Echinococcus multilocularis beta adrenergic receptor kinase 0.0041 0.0316 0.0316
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0053
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0078 0.0175
Echinococcus granulosus axis inhibition protein axin 0.004 0.0298 0.0298
Schistosoma mansoni hypothetical protein 0.0035 0.0234 0.0292
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0021 0.005 0.0111
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.1629 0.1629
Brugia malayi Common central domain of tyrosinase family protein 0.0097 0.1059 0.1326
Trichomonas vaginalis conserved hypothetical protein 0.0355 0.4473 1
Mycobacterium ulcerans short chain dehydrogenase 0.0545 0.6984 1
Schistosoma mansoni diacylglycerol kinase theta 0.0045 0.0368 0.0461
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0053
Mycobacterium ulcerans amidase 0.0075 0.0764 0.103
Loa Loa (eye worm) hypothetical protein 0.004 0.0298 0.0373
Trypanosoma cruzi monoglyceride lipase, putative 0.0355 0.4473 1
Schistosoma mansoni amidase 0.0621 0.7991 1
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0021 0.005 0.0062
Schistosoma mansoni z-protein (S1r protein) 0.004 0.0298 0.0373
Trypanosoma cruzi serine peptidase, putative 0.0021 0.005 0.0111
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0042 0.0042
Plasmodium falciparum esterase, putative 0.0021 0.005 0.0111
Plasmodium vivax hypothetical protein, conserved 0.0021 0.005 0.0111
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0335 0.4204 0.5261
Echinococcus multilocularis abhydrolase domain containing 3 0.0021 0.005 0.005
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0021 0.005 0.0017
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0298 0.0373
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0234 0.0234
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0078 0.8592
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0355 0.4473 1
Echinococcus multilocularis serine:threonine protein kinase N2 0.0064 0.0615 0.0615
Loa Loa (eye worm) hypothetical protein 0.0081 0.085 0.1064
Brugia malayi Protein C20orf22 0.0021 0.005 0.0062
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0021 0.005 0.0017
Loa Loa (eye worm) hypothetical protein 0.0621 0.7991 1
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0042 0.0042
Echinococcus granulosus protein kinase c iota type 0.0109 0.1211 0.1211
Entamoeba histolytica PH domain containing protein kinase, putative 0.007 0.0701 0.1487
Schistosoma mansoni diacylglycerol kinase theta 0.0045 0.0368 0.0461
Echinococcus granulosus abhydrolase domain containing protein 13 0.0021 0.005 0.005
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0355 0.4473 1
Echinococcus multilocularis serine threonine protein kinase 0.0226 0.2764 0.2764
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.005 0.0017
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0298 0.0298
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0164 0.1939 0.2427
Plasmodium falciparum importin beta, putative 0.0031 0.0188 0.042
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.0298 0.0298
Entamoeba histolytica ;Alias 0.0021 0.005 0.0017
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0042 0.0094
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.0298 0.0373
Loa Loa (eye worm) hypothetical protein 0.0275 0.3414 0.4272
Plasmodium falciparum esterase, putative 0.0355 0.4473 1
Entamoeba histolytica diacylglycerol kinase, putative 0.0045 0.0368 0.0736
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0109 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.005 0.0017
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0109 0.0152
Onchocerca volvulus 0.0097 0.1059 0.3017
Plasmodium falciparum alpha/beta hydrolase fold domain containing protein, putative 0.0021 0.005 0.0111
Echinococcus granulosus fatty acid amide hydrolase 1 0.0621 0.7991 0.7991
Echinococcus granulosus serine:threonine protein kinase N2 0.0064 0.0615 0.0615
Toxoplasma gondii AGC kinase 0.0064 0.0615 1
Brugia malayi Pleckstrin Homology Domain 0.0045 0.0368 0.0461
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0615 0.1294
Echinococcus multilocularis cysteine protease 0.002 0.0042 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0799 0.1787
Brugia malayi p70 ribosomal S6 kinase beta 0.0064 0.0615 0.077
Echinococcus granulosus serine:threonine protein kinase N2 0.007 0.0701 0.0701
Brugia malayi Hr1 repeat family protein 0.0064 0.0615 0.077
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.005 0.0017
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0041 0.0316 0.0395
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0097 0.1059 0.1326
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0046 0.0387 0.0387
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0109 0.0152
Loa Loa (eye worm) hypothetical protein 0.0045 0.0368 0.0461
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0021 0.005 0.0017
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0298 0.0298
Entamoeba histolytica protein kinase, putative 0.0064 0.0615 0.1294
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0184 0.2204 0.2758
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0046 0.0387 0.0484
Plasmodium vivax hypothetical protein, conserved 0.0021 0.005 0.0111
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0298 0.0298
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0021 0.005 0.0017
Schistosoma mansoni regulator of G protein signaling 0.004 0.0298 0.0373
Brugia malayi MH2 domain containing protein 0.0134 0.1546 0.1934
Brugia malayi small heat shock protein 0.0576 0.7393 0.9251
Brugia malayi protein kinase C II. 0.0184 0.2204 0.2758
Trypanosoma cruzi cysteine peptidase, putative 0.0078 0.0799 0.1787
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0042 0.0053
Schistosoma mansoni hypothetical protein 0.0045 0.0368 0.0461
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0355 0.4473 1
Echinococcus granulosus NDR protein kinase 0.0064 0.0615 0.0615
Giardia lamblia TCP-1 chaperonin subunit beta 0.0023 0.0083 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.1629 0.2039
Echinococcus granulosus snurportin 1 0.0335 0.4204 0.4204
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0188 0.305
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0021 0.005 0.0807
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.0298 0.0373
Onchocerca volvulus 0.0097 0.1059 0.3017
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.0298 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.005 0.0017
Trypanosoma cruzi cysteine peptidase, putative 0.0078 0.0799 0.1787
Leishmania major cathepsin L-like protease 0.002 0.0042 0.0094
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0021 0.005 0.0017
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0041 0.0316 0.0395
Trypanosoma brucei Serine peptidase, Clan SC, Family S09X 0.0021 0.005 0.0111
Loa Loa (eye worm) ShTK domain-containing protein 0.0097 0.1059 0.1326
Mycobacterium tuberculosis Probable oxidoreductase 0.0545 0.6984 1
Brugia malayi Protein kinase domain containing protein 0.0064 0.0615 0.077
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0042 0.0053
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0051 0.0451 0.0451
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0188 0.0188
Leishmania major importin beta-1 subunit, putative 0.0025 0.0109 0.0244
Echinococcus multilocularis Diacylglycerol kinase theta 0.0045 0.0368 0.0368
Leishmania major monoglyceride lipase, putative 0.0355 0.4473 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0298 0.0373
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.1629 0.1629
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0355 0.4473 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.005 0.0062
Plasmodium vivax PST-A protein 0.0021 0.005 0.0111
Brugia malayi MGC83647 protein 0.0021 0.005 0.0062
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0579 0.1295
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0355 0.4473 1
Plasmodium vivax PST-A protein 0.0021 0.005 0.0111
Trypanosoma brucei rac serine-threonine kinase, putative 0.0064 0.0615 0.1375
Entamoeba histolytica hypothetical protein 0.0021 0.005 0.0017
Onchocerca volvulus 0.0051 0.0451 0.1212
Loa Loa (eye worm) hypothetical protein 0.0156 0.1839 0.2301
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.0298 0.0373
Trypanosoma cruzi amidase, putative 0.0075 0.0764 0.1708
Loa Loa (eye worm) raf kinase 0.0045 0.0368 0.0461
Brugia malayi Variant SH3 domain containing protein 0.0045 0.0368 0.0461
Loa Loa (eye worm) hypothetical protein 0.0031 0.0188 0.0235
Loa Loa (eye worm) hypothetical protein 0.0045 0.0368 0.0461
Plasmodium falciparum lysophospholipase, putative 0.0021 0.005 0.0111
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0298 0.0298
Plasmodium vivax vivapain-2 0.002 0.0042 0.0094
Loa Loa (eye worm) hypothetical protein 0.0028 0.0147 0.0184
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0021 0.005 0.0062
Leishmania major cathepsin L-like protease 0.002 0.0042 0.0094
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0021 0.005 0.0111
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.1629 0.2039
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0064 0.0615 0.0615
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0064 0.0615 0.0615
Entamoeba histolytica hypothetical protein 0.004 0.0298 0.0577
Echinococcus multilocularis jun protein 0.0084 0.088 0.088
Entamoeba histolytica protein kinase, putative 0.0064 0.0615 0.1294
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.005 0.0017
Brugia malayi C1-like domain containing protein 0.0046 0.0387 0.0484
Echinococcus multilocularis monoacylglycerol lipase abhd12 0.0021 0.005 0.005
Echinococcus multilocularis snurportin 1 0.0335 0.4204 0.4204
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0615 0.1294
Schistosoma mansoni protein kinase C 0.0051 0.0451 0.0564
Loa Loa (eye worm) AGC/AKT protein kinase 0.0064 0.0615 0.077
Entamoeba histolytica hypothetical protein 0.0021 0.005 0.0017
Plasmodium falciparum alpha/beta hydrolase, putative 0.0021 0.005 0.0111
Plasmodium vivax importin-beta 2, putative 0.0031 0.0188 0.042
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0021 0.005 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0316 0.0395
Toxoplasma gondii cathepsin CPL 0.002 0.0042 0.0683
Plasmodium falciparum alpha/beta hydrolase, putative 0.0021 0.005 0.0111
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0355 0.4473 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.005 0.0062
Schistosoma mansoni regulator of G protein signaling 0.004 0.0298 0.0373
Brugia malayi Protein kinase domain containing protein 0.0046 0.0387 0.0484
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0021 0.005 0.0017
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0021 0.005 0.0111
Brugia malayi diacylglycerol kinase 0.0045 0.0368 0.0461
Loa Loa (eye worm) hypothetical protein 0.004 0.0298 0.0373
Loa Loa (eye worm) RGS-3 protein 0.004 0.0298 0.0373
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0298 0.0298
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0075 0.0764 0.0764
Toxoplasma gondii peptidase S15, putative 0.0021 0.005 0.0807
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0799 0.1787
Onchocerca volvulus 0.0045 0.0368 0.0968
Echinococcus multilocularis myotubularin protein 13 0.0045 0.0368 0.0368
Echinococcus multilocularis cysteine protease 0.002 0.0042 0.0042
Leishmania major cathepsin L-like protease 0.002 0.0042 0.0094
Plasmodium vivax PST-A protein 0.0021 0.005 0.0111
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0023 0.0083 0.0185
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0051 0.0451 0.0451
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0271 0.336 0.336
Echinococcus granulosus beta-adrenergic receptor kinase 0.0041 0.0316 0.0316
Leishmania major GTP-binding protein, putative 0.0023 0.0078 0.0175
Schistosoma mansoni regulator of G protein signaling 0.004 0.0298 0.0373
Brugia malayi Amidase family protein 0.0075 0.0764 0.0956
Brugia malayi RhoGEF domain containing protein 0.0045 0.0368 0.0461
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0042 0.0053
Echinococcus multilocularis expressed protein 0.0773 1 1
Plasmodium vivax hypothetical protein, conserved 0.0021 0.005 0.0111
Schistosoma mansoni rac gtpase activating protein 0.0045 0.0368 0.0461
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0023 0.0083 0.0092
Leishmania major hypothetical protein, conserved 0.0021 0.005 0.0111
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0615 0.1294
Plasmodium falciparum prodrug activation and resistance esterase 0.0021 0.005 0.0111
Schistosoma mansoni unc-13 (munc13) 0.0053 0.0478 0.0599
Brugia malayi hypothetical protein 0.0018 0.0014 0.0018
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0188 0.042
Schistosoma mansoni serine/threonine kinase 0.0064 0.0615 0.077
Schistosoma mansoni hypothetical protein 0.0068 0.0673 0.0842
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0075 0.0764 0.1708
Loa Loa (eye worm) hypothetical protein 0.004 0.0298 0.0373
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0023 0.0083 0.0092
Echinococcus granulosus axis inhibition protein axin 0.004 0.0298 0.0298
Toxoplasma gondii hypothetical protein 0.0021 0.005 0.0807
Mycobacterium ulcerans hypothetical protein 0.0355 0.4473 0.638
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0316 0.0395
Schistosoma mansoni fatty-acid amide hydrolase 0.0075 0.0764 0.0956
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0799 0.1787
Brugia malayi Importin beta-1 subunit 0.0031 0.0188 0.0235
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0234 0.0292
Echinococcus granulosus protein kinase c epsilon type 0.0184 0.2204 0.2204
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0147 0.2388
Leishmania major cathepsin L-like protease 0.0078 0.0799 0.1787
Plasmodium falciparum T-complex protein 1 subunit beta 0.0023 0.0083 0.0185
Loa Loa (eye worm) amidase 0.0075 0.0764 0.0956
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0045 0.0368 0.0461
Leishmania major hypothetical protein, conserved 0.0028 0.0147 0.0328
Entamoeba histolytica protein kinase, putative 0.0064 0.0615 0.1294
Echinococcus granulosus unc 13 munc13 0.0051 0.0451 0.0451
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0109 0.0244
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0615 0.1294
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0042 0.0042
Entamoeba histolytica hypothetical protein 0.0025 0.0109 0.0152
Echinococcus multilocularis regulator of G protein signaling 0.004 0.0298 0.0298
Mycobacterium ulcerans amidase 0.0075 0.0764 0.103
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0615 0.077
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0023 0.0083 0.0083
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0615 0.1294
Echinococcus granulosus N chimaerin 0.0045 0.0368 0.0368
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.1546 0.1934
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0071 0.071 0.1587
Loa Loa (eye worm) hypothetical protein 0.0097 0.1059 0.1326
Toxoplasma gondii esterase/lipase/thioesterase domain-containing protein 0.0021 0.005 0.0807
Plasmodium falciparum lysophospholipase, putative 0.0355 0.4473 1
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.2204 0.2758
Echinococcus granulosus myotubularin protein 13 0.0045 0.0368 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.336 0.4204
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0042 0.0053
Brugia malayi Protein kinase domain containing protein 0.0064 0.0615 0.077
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0084 0.088 0.088
Plasmodium falciparum exported lipase 2 0.0021 0.005 0.0111
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0064 0.0615 0.0615
Plasmodium falciparum alpha/beta hydrolase, putative 0.0021 0.005 0.0111
Echinococcus granulosus cathepsin l1 0.002 0.0042 0.0042
Plasmodium vivax lysophospholipase, putative 0.0021 0.005 0.0111
Loa Loa (eye worm) hypothetical protein 0.0045 0.0368 0.0461
Trypanosoma cruzi amidase, putative 0.0075 0.0764 0.1708
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0021 0.005 0.0111
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0298 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0298 0.0577
Echinococcus multilocularis serine:threonine protein kinase N2 0.0132 0.1526 0.1526
Loa Loa (eye worm) hypothetical protein 0.032 0.401 0.5018
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0045 0.0368 0.0461
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0298 0.0298
Brugia malayi Ras association domain family 1 isoform A 0.0045 0.0368 0.0461
Mycobacterium tuberculosis Possible lysophospholipase 0.0355 0.4473 0.6405
Brugia malayi PXA domain containing protein 0.004 0.0298 0.0373
Trypanosoma brucei monoglyceride lipase, putative 0.0355 0.4473 1
Leishmania major cathepsin L-like protease 0.002 0.0042 0.0094
Schistosoma mansoni vav2 0.0045 0.0368 0.0461
Echinococcus granulosus Phospholipase carboxylesterase 0.0021 0.005 0.005
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0075 0.0764 0.1094
Loa Loa (eye worm) T-complex protein 1 0.0023 0.0083 0.0104
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.336 0.4204
Loa Loa (eye worm) hypothetical protein 0.0201 0.2435 0.3047
Brugia malayi hypothetical protein 0.004 0.0298 0.0373
Entamoeba histolytica hypothetical protein 0.0035 0.0234 0.0432

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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