Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.6401 | 0.5929 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.6401 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.6401 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.3606 | 0.5 |
Brugia malayi | hypothetical protein | 0.0025 | 0.3606 | 0.2768 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.1159 | 0.1811 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6401 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.1159 | 0.1811 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.1159 | 0.1811 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.5908 | 0.5371 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6401 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.3606 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.3606 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6401 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.1159 | 0.1811 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.6401 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.3606 | 0.5 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.1159 | 0.1811 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.3606 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.1159 | 0.1811 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.3606 | 0.2768 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.5908 | 0.923 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.3606 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.6401 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6401 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.3606 | 0.5 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.1159 | 0.1811 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.1159 | 0.1811 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.1159 | 0.1811 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.3606 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.5908 | 0.5371 |
Brugia malayi | hypothetical protein | 0.0016 | 0.1289 | 0.0147 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.1159 | 0.1811 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.