Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0183 | 0.0229 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0862 | 0.0853 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.0862 | 0.133 |
Onchocerca volvulus | 0.0039 | 0.0862 | 0.2428 | |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0862 | 0.1878 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.0862 | 0.4314 |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.0862 | 0.1399 |
Mycobacterium ulcerans | lipase LipD | 0.0039 | 0.0862 | 0.1399 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0686 | 0.1044 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0026 | 0.042 | 0.0612 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.0862 | 0.133 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0034 | 0.0686 | 0.1475 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0906 | 0.4533 |
Loa Loa (eye worm) | histone methyltransferase | 0.0019 | 0.0178 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0862 | 0.1878 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0306 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.1888 | 0.2992 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0034 | 0.0686 | 0.0512 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0686 | 0.1044 |
Echinococcus multilocularis | chromobox protein 1 | 0.0072 | 0.1999 | 0.3172 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1194 | 0.1867 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0145 | 0.4476 | 0.4373 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.042 | 0.0241 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.1012 | 0.5063 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0183 | 0.0229 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0145 | 0.4476 | 0.4373 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0044 | 0.0004 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0039 | 0.0862 | 0.1878 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0039 | 0.0862 | 0.0853 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.1888 | 0.2992 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0034 | 0.0686 | 0.1044 |
Schistosoma mansoni | cpg binding protein | 0.0066 | 0.1788 | 0.2831 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0407 | 0.2036 |
Onchocerca volvulus | 0.0039 | 0.0862 | 0.2428 | |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0034 | 0.0686 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0862 | 0.4314 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0034 | 0.0686 | 0.1044 |
Plasmodium vivax | hypothetical protein, conserved | 0.0039 | 0.0862 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0072 | 0.1999 | 0.3172 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0862 | 0.1878 |
Entamoeba histolytica | Flap nuclease, putative | 0.0026 | 0.042 | 0.0392 |
Entamoeba histolytica | hypothetical protein | 0.0195 | 0.621 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0034 | 0.0686 | 0.0512 |
Brugia malayi | Flap endonuclease-1 | 0.0026 | 0.042 | 0.0612 |
Echinococcus multilocularis | cpg binding protein | 0.0066 | 0.1788 | 0.2831 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0044 | 0.0005 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0019 | 0.0178 | 0.0221 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0044 | 0.0004 |
Trichomonas vaginalis | chromobox protein, putative | 0.0072 | 0.1999 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0019 | 0.0181 | 0.0905 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0016 | 0.0047 | 0.0008 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0499 | 0.2497 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.042 | 0.0241 |
Loa Loa (eye worm) | beta-lactamase | 0.0039 | 0.0862 | 0.1878 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0026 | 0.0407 | 0.2036 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0686 | 0.1044 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0143 | 0.4411 | 0.7083 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0407 | 0.2036 |
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.1888 | 0.2992 |
Echinococcus granulosus | chromobox protein 1 | 0.0072 | 0.1999 | 0.3172 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0034 | 0.0686 | 0.7402 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0034 | 0.0686 | 0.1044 |
Schistosoma mansoni | chromobox protein | 0.0072 | 0.1999 | 0.3172 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0016 | 0.0047 | 0.0008 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0161 | 0.5036 | 0.6101 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0145 | 0.0727 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0044 | 0.0004 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0862 | 0.4314 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0034 | 0.0686 | 0.1474 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0016 | 0.0047 | 0.0008 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0034 | 0.0686 | 0.0632 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0039 | 0.0862 | 0.0853 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.042 | 0.0241 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0034 | 0.0686 | 0.1044 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0063 | 0.1665 | 0.3715 |
Brugia malayi | CXXC zinc finger family protein | 0.0063 | 0.1665 | 0.2632 |
Trichomonas vaginalis | chromobox protein, putative | 0.0072 | 0.1999 | 1 |
Brugia malayi | RNA binding protein | 0.0069 | 0.1888 | 0.2992 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0044 | 0.0004 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0143 | 0.4411 | 0.7083 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0039 | 0.0862 | 0.1399 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0039 | 0.0862 | 0.133 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0862 | 0.0692 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.1888 | 0.2992 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.1888 | 0.2992 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0862 | 0.1878 |
Schistosoma mansoni | flap endonuclease-1 | 0.0024 | 0.0332 | 0.0471 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0039 | 0.0862 | 0.0853 |
Brugia malayi | isocitrate dehydrogenase | 0.0034 | 0.0686 | 0.1044 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0906 | 0.1978 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0143 | 0.4411 | 0.7083 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0407 | 0.2036 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0183 | 0.0229 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0183 | 0.0229 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0181 | 0.0905 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0306 | 1 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0039 | 0.0862 | 0.1399 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0034 | 0.0686 | 0.0512 |
Mycobacterium leprae | Probable lipase LipE | 0.0039 | 0.0862 | 0.5 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0052 | 0.1309 | 0.1147 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.1888 | 0.2992 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0183 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.0862 | 0.133 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1194 | 0.2636 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0862 | 0.1878 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0044 | 0.0004 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0019 | 0.017 | 0.0207 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0044 | 0.0004 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0039 | 0.0862 | 0.133 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0862 | 0.1878 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0044 | 0.0004 |
Plasmodium falciparum | flap endonuclease 1 | 0.0026 | 0.042 | 0.47 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0026 | 0.042 | 0.3479 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0044 | 0.0005 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.1012 | 0.3839 |
Echinococcus granulosus | chromobox protein 1 | 0.0072 | 0.1999 | 0.3172 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0143 | 0.4411 | 0.7083 |
Brugia malayi | Isocitrate dehydrogenase | 0.0034 | 0.0686 | 0.1044 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0026 | 0.042 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0044 | 0.0004 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0143 | 0.4411 | 0.7083 |
Trichomonas vaginalis | esterase, putative | 0.0039 | 0.0862 | 0.4314 |
Echinococcus multilocularis | chromobox protein 1 | 0.0072 | 0.1999 | 0.3172 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0039 | 0.0862 | 0.0853 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0044 | 0.0004 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0143 | 0.4411 | 0.7083 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0499 | 0.2497 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0034 | 0.0686 | 0.1475 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.0862 | 0.133 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1194 | 0.2636 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.0862 | 0.4314 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0906 | 0.284 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0043 | 0.0987 | 0.0818 |
Entamoeba histolytica | hypothetical protein | 0.0195 | 0.621 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0662 | 0.1005 |
Toxoplasma gondii | hypothetical protein | 0.0049 | 0.1204 | 0.2994 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0183 | 0.0918 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0.0862 | 0.0692 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0183 | 0.0918 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0862 | 0.0692 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0026 | 0.0407 | 0.2036 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0195 | 0.621 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0195 | 0.621 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0251 | 0.8138 | 1 |
Brugia malayi | hypothetical protein | 0.0195 | 0.621 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0016 | 0.0047 | 0.0008 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0044 | 0.0004 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0039 | 0.0862 | 0.1399 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0987 | 0.0818 |
Onchocerca volvulus | 0.0039 | 0.0862 | 0.2428 | |
Toxoplasma gondii | ABC1 family protein | 0.0039 | 0.0862 | 0.1992 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0143 | 0.4411 | 0.7083 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0034 | 0.0686 | 0.0512 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0183 | 0.0229 |
Mycobacterium leprae | conserved hypothetical protein | 0.0039 | 0.0862 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0044 | 0.0004 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0019 | 0.0178 | 0.0221 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0026 | 0.042 | 0.0693 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.1888 | 0.2992 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0034 | 0.0686 | 0.0512 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0906 | 0.4533 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0407 | 0.2036 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0862 | 0.4314 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0026 | 0.042 | 0.2099 |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.1888 | 0.4224 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0662 | 0.1005 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0044 | 0.0004 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0407 | 0.2036 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.621 | 1 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0026 | 0.042 | 0.0864 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0016 | 0.0047 | 0.0008 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1194 | 0.1867 |
Echinococcus granulosus | flap endonuclease 1 | 0.0026 | 0.042 | 0.0612 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0143 | 0.4411 | 0.7083 |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.1888 | 0.4224 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0119 | 0.3591 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0183 | 0.0324 |
Onchocerca volvulus | 0.0063 | 0.1665 | 1 | |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0.0862 | 0.0692 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0143 | 0.4411 | 1 |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.0906 | 0.1401 |
Brugia malayi | TAR-binding protein | 0.0069 | 0.1888 | 0.2992 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0043 | 0.0987 | 0.0818 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0987 | 0.0818 |
Brugia malayi | beta-lactamase | 0.0039 | 0.0862 | 0.133 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0183 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0195 | 0.621 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0133 | 0.4079 | 0.6545 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0862 | 0.0853 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0306 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0605 | 0.1289 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0039 | 0.0862 | 0.0853 |
Schistosoma mansoni | cpg binding protein | 0.0063 | 0.1665 | 0.2632 |
Schistosoma mansoni | chromobox protein | 0.0072 | 0.1999 | 0.3172 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.0862 | 0.0853 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.1012 | 0.5063 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0662 | 0.1418 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0145 | 0.4476 | 0.4373 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0195 | 0.621 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0039 | 0.0862 | 0.0853 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0039 | 0.0862 | 0.0853 |
Mycobacterium ulcerans | hypothetical protein | 0.0161 | 0.5036 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0072 | 0.1999 | 0.4479 |
Echinococcus granulosus | cpg binding protein | 0.0066 | 0.1788 | 0.2831 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0407 | 0.2036 |
Schistosoma mansoni | cpg binding protein | 0.0066 | 0.1788 | 0.2831 |
Entamoeba histolytica | hypothetical protein | 0.0195 | 0.621 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.1888 | 0.2992 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0039 | 0.0862 | 0.133 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.1888 | 0.4224 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -5.817 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.783 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.754 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.75 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.748 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.734 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.732 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.698 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.666 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.622 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.