Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0098 | 0.0335 | 0.0927 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.004 | 0.0095 | 0.0148 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0106 | 0.0131 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0091 | 0.0124 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0038 | 0.0086 | 0.0086 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0091 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0135 | 0.0367 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.008 | 0.0259 | 0.0715 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.0174 | 0.0477 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.0214 | 0.0588 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0154 | 0.0564 | 0.0519 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0042 | 0.0104 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0145 | 0.0394 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0091 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0104 | 0.028 |
Schistosoma mansoni | coup transcription factor | 0.008 | 0.0259 | 0.0497 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0515 | 0.2042 | 0.4452 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0104 | 0.0282 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.008 | 0.0259 | 0.0497 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.008 | 0.0259 | 0.0497 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.008 | 0.0259 | 0.0715 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0142 | 0.0513 | 0.104 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.0174 | 0.0477 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.008 | 0.0259 | 0.0715 |
Echinococcus multilocularis | FTZ F1 alpha | 0.008 | 0.0259 | 0.0213 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0038 | 0.0086 | 0.023 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0059 | 0.0174 | 0.0128 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.004 | 0.0095 | 0.0107 |
Echinococcus granulosus | expressed conserved protein | 0.0093 | 0.0313 | 0.0594 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0106 | 0.0284 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0029 | 0.3036 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.008 | 0.0259 | 0.0713 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0038 | 0.0086 | 0.0039 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0086 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0141 | 0.0509 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0099 | 0.0141 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0095 | 0.0146 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0028 | 0.0047 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.004 | 0.0095 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0029 | 0.2729 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0106 | 0.0059 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0029 | 0.0071 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Brugia malayi | steroid hormone receptor | 0.008 | 0.0259 | 0.0715 |
Onchocerca volvulus | Bile acid receptor homolog | 0.008 | 0.0259 | 0.7525 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0038 | 0.0086 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0259 | 0.0713 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.008 | 0.0259 | 0.0497 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0059 | 0.0174 | 0.0128 |
Onchocerca volvulus | 0.0038 | 0.0086 | 0.1855 | |
Leishmania major | DNA polymerase eta, putative | 0.0068 | 0.0209 | 0.0507 |
Schistosoma mansoni | zinc finger protein | 0.0038 | 0.0086 | 0.0111 |
Brugia malayi | hypothetical protein | 0.0483 | 0.1911 | 0.5337 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0029 | 0.2729 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.008 | 0.0259 | 0.0713 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.004 | 0.0095 | 0.0186 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0038 | 0.0086 | 0.1855 |
Entamoeba histolytica | Flap nuclease, putative | 0.0028 | 0.0047 | 0.0051 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.008 | 0.0259 | 0.0473 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0038 | 0.0086 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0104 | 0.028 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.013 | 0.0084 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.004 | 0.0095 | 0.8183 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0889 | 0.3578 | 1 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0889 | 0.3578 | 0.7886 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.004 | 0.0095 | 1 |
Brugia malayi | ecdysteroid receptor | 0.008 | 0.0259 | 0.0715 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0214 | 0.0396 |
Schistosoma mansoni | nuclear hormone receptor | 0.0038 | 0.0086 | 0.0111 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0038 | 0.0086 | 0.0228 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.008 | 0.0259 | 0.0715 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0043 | 0.9132 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0483 | 0.1911 | 0.1873 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0044 | 0.0002 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0059 | 0.0174 | 0.0284 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0095 | 0.0146 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0091 | 0.0124 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0068 | 0.0209 | 0.0468 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0141 | 0.0509 | 0.1413 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.004 | 0.0095 | 0.0132 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0335 | 0.0665 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0038 | 0.0086 | 0.0039 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0106 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.008 | 0.0259 | 0.0715 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0095 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.008 | 0.0259 | 0.0715 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0214 | 0.0396 |
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.0214 | 0.0372 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.008 | 0.0259 | 0.7525 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Brugia malayi | nuclear receptor NHR-67 | 0.0038 | 0.0086 | 0.023 |
Schistosoma mansoni | hypothetical protein | 0.0522 | 0.2072 | 0.4534 |
Echinococcus multilocularis | dna polymerase kappa | 0.004 | 0.0095 | 0.0048 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.004 | 0.0095 | 0.0254 |
Echinococcus multilocularis | tumor protein p63 | 0.0341 | 0.1329 | 0.1288 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0259 | 0.0713 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0091 | 0.0176 |
Schistosoma mansoni | survival motor neuron protein | 0.0098 | 0.0335 | 0.0665 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.008 | 0.0259 | 0.0713 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0099 | 0.0338 | 0.0936 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.008 | 0.0259 | 0.0715 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0028 | 0.0047 | 0.0715 |
Brugia malayi | TAR-binding protein | 0.0069 | 0.0214 | 0.0588 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0029 | 0.0071 |
Echinococcus granulosus | muscleblind protein | 0.0154 | 0.0564 | 0.1153 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0038 | 0.0086 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.004 | 0.0095 | 0.0186 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.008 | 0.0259 | 0.0715 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.008 | 0.0259 | 0.0473 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.008 | 0.0259 | 0.0213 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0091 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0104 | 0.028 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0099 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0029 | 0.0069 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0029 | 0.3036 |
Trypanosoma brucei | unspecified product | 0.004 | 0.0095 | 0.0146 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.008 | 0.0259 | 0.0715 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.008 | 0.0259 | 0.0715 |
Brugia malayi | conserved hypotetical protein | 0.0038 | 0.0086 | 0.023 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0029 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0104 | 0.028 |
Echinococcus granulosus | dna polymerase eta | 0.0068 | 0.0209 | 0.0361 |
Echinococcus granulosus | dna polymerase kappa | 0.004 | 0.0095 | 0.0107 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.008 | 0.0259 | 0.0715 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0059 | 0.0174 | 0.0284 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0141 | 0.0509 | 0.0464 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0099 | 0.0338 | 0.0871 |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.0214 | 0.0586 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.1121 | 0.4528 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.0214 | 0.0167 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.008 | 0.0259 | 0.0473 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0042 | 0.0104 | 0.028 |
Schistosoma mansoni | thyroid hormone receptor | 0.008 | 0.0259 | 0.0497 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0259 | 0.0713 |
Echinococcus multilocularis | expressed conserved protein | 0.0093 | 0.0313 | 0.0268 |
Plasmodium falciparum | flap endonuclease 1 | 0.0028 | 0.0047 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0259 | 0.0713 |
Brugia malayi | Flap endonuclease-1 | 0.0028 | 0.0047 | 0.0122 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0038 | 0.0086 | 0.023 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Leishmania major | DNA polymerase eta, putative | 0.004 | 0.0095 | 0.0188 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0029 | 0.2729 |
Trypanosoma brucei | unspecified product | 0.0028 | 0.0044 | 0.0002 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.008 | 0.0259 | 0.0213 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.008 | 0.0259 | 0.0715 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0142 | 0.0513 | 0.0468 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0047 | 0.0011 |
Onchocerca volvulus | 0.008 | 0.0259 | 0.7525 | |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0106 | 0.0131 |
Giardia lamblia | DINP protein human, muc B family | 0.004 | 0.0095 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0099 | 0.0141 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0104 | 0.0282 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0095 | 0.0146 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0029 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0043 | 0.0041 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0889 | 0.3578 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0186 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0038 | 0.0086 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0106 | 0.0284 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0141 | 0.0509 | 0.1031 |
Onchocerca volvulus | 0.005 | 0.0135 | 0.3483 | |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.008 | 0.0259 | 0.0473 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0029 | 0.2729 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0141 | 0.0509 | 0.0464 |
Loa Loa (eye worm) | DR-78 | 0.0038 | 0.0086 | 0.0228 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0044 | 0.0002 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0043 | 0.0112 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0038 | 0.0086 | 0.0111 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Schistosoma mansoni | nuclear hormone receptor | 0.008 | 0.0259 | 0.0497 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.008 | 0.0259 | 0.0497 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.008 | 0.0259 | 0.0713 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0099 | 0.0338 | 0.065 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0038 | 0.0086 | 0.0039 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.008 | 0.0259 | 0.0715 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.0564 | 0.1566 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0259 | 0.0713 |
Brugia malayi | nuclear hormone receptor | 0.0038 | 0.0086 | 0.023 |
Brugia malayi | Muscleblind-like protein | 0.0154 | 0.0564 | 0.1567 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.008 | 0.0259 | 0.0473 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.1078 | 0.4354 | 0.4328 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0889 | 0.3578 | 1 |
Echinococcus multilocularis | geminin | 0.0522 | 0.2072 | 0.2035 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0038 | 0.0086 | 0.023 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0028 | 0.0047 | 0.012 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0889 | 0.3578 | 1 |
Echinococcus granulosus | geminin | 0.0522 | 0.2072 | 0.452 |
Loa Loa (eye worm) | steroid hormone receptor | 0.008 | 0.0259 | 0.0713 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.0214 | 0.0586 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0091 | 0.0099 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0029 | 0.2729 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0141 | 0.0509 | 0.1031 |
Onchocerca volvulus | 0.0098 | 0.0335 | 1 | |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.008 | 0.0259 | 0.7525 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0889 | 0.3578 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0059 | 0.0174 | 0.0308 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0038 | 0.0086 | 0.0086 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.008 | 0.0259 | 0.0715 |
Schistosoma mansoni | thyroid hormone receptor | 0.008 | 0.0259 | 0.0497 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.004 | 0.0095 | 1 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0106 | 0.0286 |
Echinococcus granulosus | tumor protein p63 | 0.0341 | 0.1329 | 0.2861 |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.0214 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.0564 | 0.1566 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.008 | 0.0259 | 0.0497 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0029 | 0.0069 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0141 | 0.0509 | 0.1415 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0483 | 0.1911 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0038 | 0.0086 | 0.0039 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0091 | 0.0045 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0059 | 0.0174 | 0.0308 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0038 | 0.0086 | 0.0039 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0028 | 0.0044 | 0.0002 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0042 | 0.0104 | 0.0152 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0889 | 0.3578 | 0.7881 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0259 | 0.0713 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0038 | 0.0086 | 0.0086 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.008 | 0.0259 | 0.0213 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.008 | 0.0259 | 0.0497 |
Onchocerca volvulus | 0.0038 | 0.0086 | 0.1855 | |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.008 | 0.0259 | 0.0213 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.004 | 0.0095 | 0.0132 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0095 | 1 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0889 | 0.3578 | 0.3548 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0889 | 0.3578 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0038 | 0.0086 | 0.1855 |
Loa Loa (eye worm) | hypothetical protein | 0.0483 | 0.1911 | 0.5336 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0214 | 0.0396 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0042 | 0.0104 | 0.0152 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.008 | 0.0259 | 0.0473 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0091 | 0.0176 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.008 | 0.0259 | 0.0213 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0004 | 0.0422 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0214 | 0.0396 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0106 | 0.0155 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0043 | 0.9132 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.004 | 0.0095 | 0.0048 |
Echinococcus multilocularis | muscleblind protein | 0.0154 | 0.0564 | 0.0519 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0029 | 0.2729 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0068 | 0.0209 | 0.0468 |
Schistosoma mansoni | nuclear receptor | 0.0038 | 0.0086 | 0.0111 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0029 | 0.2729 |
Schistosoma mansoni | DNA polymerase eta | 0.0068 | 0.0209 | 0.0385 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0043 | 0.011 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.0135 | 0.0222 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0038 | 0.0086 | 0.0086 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.008 | 0.0259 | 0.0715 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0029 | 0.0071 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0141 | 0.0509 | 0.1054 |
Brugia malayi | tailless protein | 0.0038 | 0.0086 | 0.023 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0101 | 0.0344 | 0.0687 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.008 | 0.0259 | 0.0213 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.008 | 0.0259 | 0.0473 |
Trypanosoma brucei | unspecified product | 0.0028 | 0.0044 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0104 | 0.028 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0029 | 0.2729 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.008 | 0.0259 | 0.0497 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0214 | 0.0396 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0099 | 0.0338 | 0.0292 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0099 | 0.0141 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.1121 | 0.4528 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0042 | 0.0104 | 0.0057 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0029 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0042 | 0.0104 | 0.0282 |
Brugia malayi | nuclear hormone receptor | 0.008 | 0.0259 | 0.0715 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0038 | 0.0086 | 0.023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.008 | 0.0259 | 0.0713 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0259 | 0.0713 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.008 | 0.0259 | 0.0213 |
Echinococcus granulosus | FTZ F1 alpha | 0.008 | 0.0259 | 0.0473 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.008 | 0.0259 | 0.0713 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0047 | 0.0051 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.008 | 0.0259 | 0.0715 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.008 | 0.0259 | 0.0213 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0028 | 0.0047 | 0.0011 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0059 | 0.0174 | 0.0308 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0038 | 0.0086 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0259 | 0.0713 |
Schistosoma mansoni | hypothetical protein | 0.0522 | 0.2072 | 0.4534 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0038 | 0.0086 | 0.0111 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0106 | 0.0059 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0086 | 0.023 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0515 | 0.2042 | 0.2004 |
Brugia malayi | nuclear receptor NHR-88 | 0.0038 | 0.0086 | 0.023 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0068 | 0.0209 | 0.0574 |
Brugia malayi | nuclear receptor RXR | 0.0038 | 0.0086 | 0.023 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.004 | 0.0095 | 0.8183 |
Schistosoma mansoni | nuclear hormone receptor | 0.0038 | 0.0086 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0338 | 0.0935 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.008 | 0.0259 | 0.0713 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0004 | 0.5 |
Brugia malayi | ecdysone receptor | 0.0038 | 0.0086 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0209 | 0.0572 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0042 | 0.0104 | 0.0128 |
Brugia malayi | nuclear receptor NHR-88 | 0.008 | 0.0259 | 0.0715 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0086 | 0.0228 |
Echinococcus multilocularis | dna polymerase eta | 0.0068 | 0.0209 | 0.0162 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.008 | 0.0259 | 0.0497 |
Schistosoma mansoni | nuclear receptor | 0.0038 | 0.0086 | 0.0111 |
Brugia malayi | nuclear receptor RXR | 0.0042 | 0.0104 | 0.0282 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0889 | 0.3578 | 1 |
Brugia malayi | RNA binding protein | 0.0069 | 0.0214 | 0.0588 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0043 | 0.9132 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0174 | 0.0476 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.004 | 0.0095 | 0.0256 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0141 | 0.0509 | 0.1054 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0038 | 0.0086 | 0.0111 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0038 | 0.0086 | 0.0228 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0095 | 0.0146 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | < 5 % | Inhibition of human C-terminal His-tagged AdoMetDC assessed as release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine at 100 uM | ChEMBL. | 19209891 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.