Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0119 | 1 | 0.5 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0032 | 0 | 0.5 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0119 | 1 | 1 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0032 | 0 | 0.5 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0032 | 0 | 0.5 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0032 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.4283 | 0.2796 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0032 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0096 | 0.7406 | 0.6731 |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.4283 | 0.2796 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0119 | 1 | 1 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0119 | 1 | 1 |
Loa Loa (eye worm) | phosphofructokinase | 0.0119 | 1 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0119 | 1 | 1 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0119 | 1 | 0.5 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0119 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0069 | 0.4283 | 0.2796 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0032 | 0 | 0.5 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0119 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.4283 | 0.2796 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.7406 | 0.6731 |
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.4283 | 0.2796 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0119 | 1 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0119 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.4283 | 0.2796 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0119 | 1 | 1 |
Schistosoma mansoni | eyes absent homolog | 0.0096 | 0.7406 | 0.6731 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0032 | 0 | 0.5 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0119 | 1 | 0.5 |
Brugia malayi | 6-phosphofructokinase | 0.0119 | 1 | 1 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0119 | 1 | 0.5 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0032 | 0 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0069 | 0.4283 | 0.2796 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0119 | 1 | 0.5 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0119 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.4283 | 0.2796 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0119 | 1 | 1 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0119 | 1 | 0.5 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0119 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.4283 | 0.2796 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.4283 | 0.2796 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0119 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.4283 | 0.2796 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.4283 | 0.2796 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0119 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.4283 | 0.2796 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0032 | 0 | 0.5 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0032 | 0 | 0.5 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0119 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.7406 | 0.6731 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.