Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0032 | 0.1463 | 0.4775 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0069 | 0.5895 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0045 | 0.3064 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0045 | 0.3064 | 0.3064 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.3064 | 0.5198 |
Echinococcus granulosus | dna polymerase eta | 0.0045 | 0.3064 | 0.3064 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0103 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0103 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.5895 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0045 | 0.3064 | 0.3064 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0045 | 0.3064 | 1 |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.0103 | 1 | 1 |
Brugia malayi | Melibiase family protein | 0.0069 | 0.5895 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0069 | 0.5895 | 0.5895 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0045 | 0.3064 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0032 | 0.1463 | 0.4775 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0 | 0.5 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.0103 | 1 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0045 | 0.3064 | 0.5198 |
Toxoplasma gondii | melibiase subfamily protein | 0.0103 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0069 | 0.5895 | 0.5895 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0103 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0103 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.