TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 479.787 | Formula: C22H21Cl3N4O2
H donors: 2 H acceptors: 3 LogP: 6.56 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: Clc1ccc(cc1)c1c(C)c(nn1c1ccc(cc1Cl)Cl)C(=O)NC(=O)NC(C)(C)C
InChi: 1S/C22H21Cl3N4O2/c1-12-18(20(30)26-21(31)27-22(2,3)4)28-29(17-10-9-15(24)11-16(17)25)19(12)13-5-7-14(23)8-6-13/h5-11H,1-4H3,(H2,26,27,30,31)
InChiKey: NTYBEEOJKCSIQW-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	chromobox protein 1	0.007	0.0391	0.0813
Echinococcus multilocularis	methionine aminopeptidase, type I	0.0042	0.0035	0.0027
Schistosoma mansoni	hypothetical protein	0.0179	0.1779	0.4757
Mycobacterium ulcerans	aminopeptidase	0.0042	0.0035	0.0072
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0199	0.2033	0.4307
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0061	0.0274	0.0713
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0085	0.0077
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0274	0.0582
Brugia malayi	DNA-binding protein, 42 kDa containing protein	0.0042	0.0035	0.0075
Leishmania major	aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Echinococcus multilocularis	lysine specific demethylase 5A	0.0074	0.0437	0.0428
Trypanosoma brucei	hypothetical protein, conserved	0.0077	0.0479	0.1001
Schistosoma mansoni	aminopeptidase P homologue (M24 family)	0.0042	0.0035	0.0072
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0046	0.0085	0.0181
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Toxoplasma gondii	proliferation-associated protein 2G4, putative	0.0042	0.0035	0.0057
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0085	0.0163
Brugia malayi	Heterochromatin protein 1	0.007	0.0391	0.0831
Echinococcus multilocularis	xaa Pro dipeptidase	0.0042	0.0035	0.0027
Trypanosoma cruzi	Metallopeptidase family M24, putative	0.0042	0.0035	0.0057
Trypanosoma brucei	Xaa-Pro aminopeptidase, putative	0.0042	0.0035	0.0057
Trypanosoma brucei	methionine aminopeptidase 2, putative	0.0042	0.0035	0.0057
Leishmania major	aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Plasmodium vivax	hypothetical protein, conserved	0.0061	0.0274	0.0511
Schistosoma mansoni	tyrosyl-DNA phosphodiesterase	0.0071	0.0408	0.1074
Echinococcus granulosus	survival motor neuron protein 1	0.0241	0.2563	0.5435
Brugia malayi	metallopeptidase family M24 containing protein	0.0042	0.0035	0.0075
Brugia malayi	metallopeptidase family M24 containing protein	0.0042	0.0035	0.0075
Onchocerca volvulus	Dipeptidase C homolog	0.0042	0.0035	0.1293
Trypanosoma brucei	methionine aminopeptidase, type I, putative	0.041	0.4708	1
Brugia malayi	PHD-finger family protein	0.0061	0.0274	0.0582
Toxoplasma gondii	hypothetical protein	0.0077	0.0479	0.1001
Trypanosoma cruzi	aminopeptidase P, putative	0.0042	0.0035	0.0057
Entamoeba histolytica	hypothetical protein, conserved	0.0042	0.0035	0.0669
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Trypanosoma brucei	metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0104	0.0826	0.1755
Entamoeba histolytica	tyrosyl-DNA phosphodiesterase, putative	0.0071	0.0408	1
Echinococcus multilocularis	chromobox protein 1	0.007	0.0391	0.0383
Giardia lamblia	PHD finger protein 15	0.0061	0.0274	1
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0049	0.0126	0.0267
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0071	0.0408	0.085
Loa Loa (eye worm)	jmjC domain-containing protein	0.0126	0.1097	0.233
Schistosoma mansoni	hypothetical protein	0.0049	0.0126	0.0314
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0061	0.0274	0.0266
Echinococcus multilocularis	methionyl aminopeptidase 1 (M24 family)	0.041	0.4708	0.4703
Echinococcus granulosus	jumonji domain containing protein	0.0085	0.0577	0.1209
Brugia malayi	Methionine aminopeptidase protein type I	0.041	0.4708	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0085	0.0206
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Echinococcus multilocularis	peregrin	0.0061	0.0274	0.0266
Schistosoma mansoni	methionyl aminopeptidase 1 (M24 family)	0.0333	0.373	1
Brugia malayi	metallopeptidase family M24 containing protein	0.0042	0.0035	0.0075
Echinococcus multilocularis	xaa Pro dipeptidase	0.0042	0.0035	0.0027
Trypanosoma brucei	metallo- peptidase, Clan MG, Family M24	0.041	0.4708	1
Schistosoma mansoni	methionyl aminopeptidase 2 (M24 family)	0.0042	0.0035	0.0072
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.004	0.0009	0.0223
Schistosoma mansoni	chromobox protein	0.007	0.0391	0.1027
Echinococcus granulosus	tyrosyl DNA phosphodiesterase 1	0.0071	0.0408	0.085
Schistosoma mansoni	hypothetical protein	0.0179	0.1779	0.4757
Loa Loa (eye worm)	methionine aminopeptidase type I	0.041	0.4708	1
Schistosoma mansoni	chromobox protein	0.007	0.0391	0.1027
Entamoeba histolytica	aminopeptidase, putative	0.0042	0.0035	0.0669
Trypanosoma brucei	metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Mycobacterium tuberculosis	Methionine aminopeptidase MapB (map) (peptidase M)	0.0333	0.373	1
Mycobacterium ulcerans	methionine aminopeptidase	0.0333	0.373	1
Plasmodium falciparum	HP12 protein homolog, putative	0.0077	0.0479	0.0949
Brugia malayi	initiation factor 2-associated protein.	0.0042	0.0035	0.0075
Brugia malayi	Inositol-1	0.004	0.0009	0.0019
Trichomonas vaginalis	chromobox protein, putative	0.0042	0.0038	0.0969
Echinococcus multilocularis	jumonji domain containing protein	0.0085	0.0577	0.0569
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.004	0.0009	0.0223
Echinococcus granulosus	Proliferation associated protein 2G4	0.0042	0.0035	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0035	0.0075
Entamoeba histolytica	peptidase, putative	0.0042	0.0035	0.0669
Trypanosoma cruzi	metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Loa Loa (eye worm)	tyrosyl-DNA phosphodiesterase	0.0071	0.0408	0.0867
Trypanosoma cruzi	hypothetical protein, conserved	0.0077	0.0479	0.1001
Loa Loa (eye worm)	DNA-binding protein	0.0042	0.0035	0.0075
Mycobacterium ulcerans	methionine aminopeptidase MapB	0.0333	0.373	1
Onchocerca volvulus		0.0049	0.0126	0.4586
Echinococcus granulosus	Xaa Pro aminopeptidase 3	0.0042	0.0035	0.0057
Wolbachia endosymbiont of Brugia malayi	methionine aminopeptidase	0.0333	0.373	1
Leishmania major	aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Trichomonas vaginalis	inositol monophosphatase, putative	0.004	0.0009	0.0223
Echinococcus multilocularis	chromobox protein 1	0.007	0.0391	0.0383
Toxoplasma gondii	PHD-finger domain-containing protein	0.0061	0.0274	0.0565
Echinococcus granulosus	lysine specific demethylase 5A	0.0074	0.0437	0.0911
Trypanosoma cruzi	metallo- peptidase, Clan MG, Family M24	0.041	0.4708	1
Chlamydia trachomatis	methionine aminopeptidase	0.0333	0.373	1
Echinococcus multilocularis	transcription factor Dp 1	0.0041	0.0026	0.0018
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0074	0.0437	0.115
Plasmodium vivax	methionine aminopeptidase 1b, putative	0.041	0.4708	1
Trypanosoma brucei	Metallopeptidase family M24, putative	0.0042	0.0035	0.0057
Trypanosoma cruzi	metallo-peptidase, Clan MG, Family M24, putative	0.0042	0.0035	0.0057
Echinococcus granulosus	transcription factor Dp 1	0.0041	0.0026	0.0037
Toxoplasma gondii	PHD-finger domain-containing protein	0.0061	0.0274	0.0565
Leishmania major	hypothetical protein, conserved	0.0077	0.0479	0.1001
Loa Loa (eye worm)	metallopeptidase family M24 containing protein	0.0042	0.0035	0.0075
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Entamoeba histolytica	methionine aminopeptidase, putative	0.0042	0.0035	0.0669
Plasmodium vivax	hypothetical protein, conserved	0.0077	0.0479	0.0949
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0085	0.0206
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Echinococcus multilocularis	Xaa Pro aminopeptidase 3	0.0042	0.0035	0.0027
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Plasmodium falciparum	methionine aminopeptidase 1b, putative	0.041	0.4708	1
Schistosoma mansoni	aminopeptidase P1 (M24 family)	0.0042	0.0035	0.0072
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0035	0.0075
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0199	0.2033	0.2026
Treponema pallidum	methionine aminopeptidase (map)	0.0333	0.373	1
Echinococcus granulosus	methionine aminopeptidase type I	0.0042	0.0035	0.0057
Echinococcus multilocularis	geminin	0.0179	0.1779	0.1772
Echinococcus multilocularis	xaa pro aminopeptidase	0.0042	0.0035	0.0027
Echinococcus multilocularis	survival motor neuron protein 1	0.0241	0.2563	0.2556
Toxoplasma gondii	peptidase D, putative	0.0042	0.0035	0.0057
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0046	0.0085	0.0181
Onchocerca volvulus	FACT complex subunit SPT16 homolog	0.0042	0.0035	0.1293
Toxoplasma gondii	methionine aminopeptidase	0.0333	0.373	0.7919
Echinococcus granulosus	xaa pro aminopeptidase	0.0042	0.0035	0.0057
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Trypanosoma cruzi	metallo-peptidase, Clan MG, Family M24, putative	0.0042	0.0035	0.0057
Leishmania major	methionine aminopeptidase 2, putative	0.0042	0.0035	0.0057
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0042	0.0038	0.1382
Schistosoma mansoni	proliferation-associated protein 2G4 38kDa (M24 family)	0.0042	0.0035	0.0072
Echinococcus multilocularis	FACT complex subunit SPT16	0.0042	0.0035	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0035	0.0075
Echinococcus multilocularis	Proliferation associated protein 2G4	0.0042	0.0035	0.0027
Trichomonas vaginalis	chromobox protein, putative	0.007	0.0391	1
Leishmania major	tyrosyl-DNA phosphodiesterase 1	0.0071	0.0408	0.085
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0071	0.0408	0.085
Loa Loa (eye worm)	inositol-1	0.004	0.0009	0.0019
Brugia malayi	Bromodomain containing protein	0.0061	0.0274	0.0582
Trichomonas vaginalis	chromobox protein, putative	0.007	0.0391	1
Toxoplasma gondii	methionine aminopeptidase, type i, putative	0.0333	0.373	0.7919
Entamoeba histolytica	Xaa-Pro dipeptidase, putative	0.0042	0.0035	0.0669
Echinococcus granulosus	methionyl aminopeptidase 2	0.0042	0.0035	0.0057
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0085	0.0163
Onchocerca volvulus		0.0042	0.0035	0.1293
Trypanosoma cruzi	Metallopeptidase family M24, putative	0.0042	0.0035	0.0057
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0235	0.2479	0.6615
Echinococcus granulosus	geminin	0.0179	0.1779	0.3768
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Leishmania major	aminopeptidase P, putative,metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Toxoplasma gondii	creatinase domain-containing protein	0.0042	0.0035	0.0057
Echinococcus multilocularis	methionyl aminopeptidase 1 (M24 family)	0.0333	0.373	0.3725
Echinococcus granulosus	xaa Pro dipeptidase	0.0042	0.0035	0.0057
Trypanosoma brucei	metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Brugia malayi	jmjC domain containing protein	0.0074	0.0437	0.0928
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0085	0.0077
Onchocerca volvulus	Alhambra homolog	0.0061	0.0274	1
Mycobacterium ulcerans	dipeptidase PepE	0.0042	0.0035	0.0072
Toxoplasma gondii	methionine aminopeptidase	0.041	0.4708	1
Leishmania major	hypothetical protein, conserved	0.0042	0.0035	0.0057
Echinococcus multilocularis	tyrosyl DNA phosphodiesterase 1	0.0071	0.0408	0.04
Leishmania major	transcription factor-like protein	0.0042	0.0035	0.0057
Toxoplasma gondii	methionine aminopeptidase 2, putative	0.0042	0.0035	0.0057
Toxoplasma gondii	transcriptional elongation factor FACT140	0.0042	0.0035	0.0057
Brugia malayi	Tyrosyl-DNA phosphodiesterase family protein	0.0071	0.0408	0.0867
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Trypanosoma cruzi	metallo- peptidase, Clan MG, Family M24	0.041	0.4708	1
Trypanosoma cruzi	Metallopeptidase family M24/FACT complex subunit (SPT16/CDC68)/Histone chaperone Rttp106-like, putative	0.0042	0.0035	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0241	0.2563	0.5444
Schistosoma mansoni	proliferation-associated protein 2G4 38kDa (M24 family)	0.0042	0.0035	0.0072
Schistosoma mansoni	jumonji domain containing protein	0.0158	0.1512	0.404
Onchocerca volvulus	Methionine aminopeptidase 2 homolog	0.0042	0.0035	0.1293
Trypanosoma brucei	methionine aminopeptidase, putative	0.041	0.4708	1
Brugia malayi	jmjC domain containing protein	0.0199	0.2033	0.4317
Mycobacterium leprae	PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M)	0.0333	0.373	1
Loa Loa (eye worm)	PHD-finger family protein	0.0061	0.0274	0.0582
Schistosoma mansoni	hypothetical protein	0.0061	0.0274	0.0713
Echinococcus granulosus	PHD finger protein rhinoceros	0.0061	0.0274	0.0565
Trypanosoma brucei	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0071	0.0408	0.085
Mycobacterium ulcerans	dipeptidase	0.0042	0.0035	0.0072
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0074	0.0437	0.115
Trypanosoma cruzi	metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Trichomonas vaginalis	chromobox protein, putative	0.0042	0.0038	0.0969
Mycobacterium ulcerans	cytoplasmic peptidase PepQ	0.0042	0.0035	0.0072
Loa Loa (eye worm)	initiation factor 2-associated protein	0.0042	0.0035	0.0075
Mycobacterium tuberculosis	Methionine aminopeptidase MapA (map) (peptidase M) (MetAP)	0.0333	0.373	1
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Plasmodium falciparum	phd finger protein, putative	0.0061	0.0274	0.0511
Schistosoma mansoni	survival motor neuron protein	0.0049	0.0126	0.0314
Leishmania major	aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Echinococcus granulosus	xaa Pro dipeptidase	0.0042	0.0035	0.0057
Trypanosoma cruzi	aminopeptidase P1, putative	0.0042	0.0035	0.0057
Trypanosoma brucei	Facilitates chromatin transcription complex subunit spt16	0.0042	0.0035	0.0057
Brugia malayi	hypothetical protein	0.0241	0.2563	0.5444
Plasmodium vivax	methionine aminopeptidase 1a, putative	0.0333	0.373	0.7907
Schistosoma mansoni	peptidase	0.0042	0.0035	0.0072
Plasmodium falciparum	methionine aminopeptidase 1a, putative	0.0333	0.373	0.7907
Trypanosoma cruzi	metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Echinococcus granulosus	methionyl aminopeptidase 1 M24 family	0.041	0.4708	1
Schistosoma mansoni	methionyl aminopeptidase 1 (M24 family)	0.0333	0.373	1
Loa Loa (eye worm)	heterochromatin protein 1	0.007	0.0391	0.0831
Schistosoma mansoni	Xaa-Pro dipeptidase (M24 family)	0.0042	0.0035	0.0072
Trypanosoma cruzi	metallo-peptidase, Clan MG, Family M24	0.0042	0.0035	0.0057
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0085	0.0206
Trichomonas vaginalis	Clan MG, familly M24, aminopeptidase P-like metallopeptidase	0.0042	0.0035	0.0906
Mycobacterium leprae	PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP)	0.0333	0.373	1
Wolbachia endosymbiont of Brugia malayi	Xaa-Pro aminopeptidase	0.0042	0.0035	0.0072
Schistosoma mansoni	chromatin-specific transcription elongation factor 140 kDa subunit (M24 family)	0.0042	0.0035	0.0072
Loa Loa (eye worm)	jmjC domain-containing protein	0.0074	0.0437	0.0928
Trypanosoma cruzi	hypothetical protein, conserved	0.0077	0.0479	0.1001
Echinococcus multilocularis	methionyl aminopeptidase 2	0.0042	0.0035	0.0027
Echinococcus granulosus	FACT complex subunit SPT16	0.0042	0.0035	0.0057
Leishmania major	methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24	0.041	0.4708	1
Echinococcus granulosus	chromobox protein 1	0.007	0.0391	0.0813
Echinococcus granulosus	peregrin	0.0061	0.0274	0.0565

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL521166

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1016156