Detailed information for compound 1016194

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 322.401 | Formula: C20H22N2O2
  • H donors: 1 H acceptors: 1 LogP: 1.78 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=C[C@]12CN([C@H]3[C@@H]2[C@]2([C@H]4C[C@@H]1[C@@H]3CO4)C(=O)Nc1c2cccc1)C
  • InChi: 1S/C20H22N2O2/c1-3-19-10-22(2)16-11-9-24-15(8-13(11)19)20(17(16)19)12-6-4-5-7-14(12)21-18(20)23/h3-7,11,13,15-17H,1,8-10H2,2H3,(H,21,23)/t11-,13+,15+,16+,17-,19-,20-/m0/s1
  • InChiKey: NFYYATWFXNPTRM-QJICHLCESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus cathepsin L 0.0015 0.0011 0.001
Plasmodium vivax hypothetical protein, conserved 0.0106 0.0314 0.4403
Brugia malayi sulfakinin receptor protein 0.0118 0.0354 0.0518
Mycobacterium tuberculosis Probable hydrolase 0.0106 0.0314 0.1401
Echinococcus multilocularis cathepsin L 0.0015 0.0011 0.001
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.016 0.016
Echinococcus multilocularis RUN 0.0064 0.0175 0.0174
Schistosoma mansoni hypothetical protein 0.0051 0.0132 0.0132
Brugia malayi putative neuropeptide receptor NPR1 0.0118 0.0354 0.0518
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0118 0.0354 0.1375
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Leishmania major phosphoglycerate kinase C, glycosomal 0.0165 0.0512 0.2333
Mycobacterium ulcerans bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.0017 0.0015 0.006
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0035 0.0076 0.0331
Loa Loa (eye worm) hypothetical protein 0.0489 0.1596 0.2358
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0059 0.0143
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0199 0.0626 0.8831
Echinococcus granulosus cathepsin L cysteine protease 0.0015 0.0011 0.001
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.0029 0.0029
Brugia malayi jmjC domain containing protein 0.0035 0.0076 0.0107
Wolbachia endosymbiont of Brugia malayi bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.0017 0.0015 0.0169
Brugia malayi ORL1-like opioid receptor 0.0118 0.0354 0.0518
Echinococcus multilocularis somatostatin receptor 0.0118 0.0354 0.0353
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0165 0.0512 0.7209
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0453 0.0452
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0059 0.0255
Schistosoma mansoni hypothetical protein 0.0084 0.0241 0.0241
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.043 0.0429
Brugia malayi Cathepsin L-like precursor 0.002 0.0026 0.0034
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1248 0.4136 1
Schistosoma mansoni hypothetical protein 0.0039 0.009 0.009
Schistosoma mansoni sex comb on midleg homolog 0.0095 0.0279 0.0279
Schistosoma mansoni hypothetical protein 0.0023 0.0036 0.0036
Onchocerca volvulus 0.003 0.0059 0.0183
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0227 0.0719 0.0719
Trichomonas vaginalis ran, putative 0.0021 0.003 0.0073
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.061 0.2 1
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0314 0.0759
Echinococcus granulosus sex peptide receptor 0.0118 0.0354 0.0353
Leishmania major mitochondrial DNA polymerase beta 0.0664 0.2183 1
Echinococcus multilocularis JmjC domain containing protein 4 0.0035 0.0076 0.0075
Plasmodium falciparum M17 leucyl aminopeptidase 0.0224 0.0709 0.9612
Mycobacterium ulcerans leucyl aminopeptidase 0.0224 0.0709 0.3534
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0104 0.0462
Brugia malayi cathepsin L-like precursor 0.002 0.0026 0.0034
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0039 0.009 0.0089
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0172 0.2393
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0163 0.0731
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0095 0.0279 0.0279
Brugia malayi 3'-5' exonuclease family protein 0.0028 0.0053 0.0073
Trypanosoma brucei phosphoglycerate kinase 0.0165 0.0512 0.2333
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0118 0.0354 0.0354
Onchocerca volvulus 0.0106 0.0314 0.1215
Onchocerca volvulus 0.0106 0.0314 0.1215
Schistosoma mansoni ap endonuclease 0.0039 0.0089 0.0089
Mycobacterium tuberculosis Conserved protein 0.0106 0.0314 0.1401
Loa Loa (eye worm) DnaJ domain-containing protein 0.0134 0.041 0.0604
Echinococcus granulosus allatostatin A receptor 0.0118 0.0354 0.0353
Echinococcus granulosus g protein coupled receptor 0.0118 0.0354 0.0353
Schistosoma mansoni myosin xvIII 0.0118 0.0354 0.0354
Plasmodium vivax glutathione reductase, putative 0.0037 0.0085 0.1157
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0202 0.0489
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.0277 0.1233
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0015 0.0011 0.0011
Echinococcus granulosus neutral alpha glucosidase AB 0.0194 0.0611 0.061
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0118 0.0354 0.0354
Entamoeba histolytica exosome component 10, putative 0.0028 0.0053 0.0101
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0163 0.0731
Loa Loa (eye worm) MH2 domain-containing protein 0.0244 0.0775 0.1144
Schistosoma mansoni hypothetical protein 0.0118 0.0354 0.0354
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0087 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0059 0.0143
Brugia malayi G protein-coupled receptor 0.0118 0.0354 0.0518
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0198 0.0197
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.003 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0011 0.0027
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.2034 0.6765 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0118 0.0354 0.0354
Entamoeba histolytica hypothetical protein 0.0071 0.0198 0.0454
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.003 0.0029
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0876 0.2891 0.4273
Trypanosoma cruzi WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0037 0.0082 0.0362
Echinococcus granulosus somatostatin receptor 0.0118 0.0354 0.0353
Echinococcus multilocularis neuropeptide receptor 0.0118 0.0354 0.0353
Treponema pallidum fructose-bisphosphate aldolase 0.1248 0.4136 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.018 0.0562 0.0561
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0129 0.0393 0.0392
Brugia malayi hypothetical protein 0.0118 0.0354 0.0518
Schistosoma mansoni terminal deoxycytidyl transferase 0.0139 0.0424 0.0424
Trichomonas vaginalis alpha-glucosidase, putative 0.0194 0.0611 0.1476
Schistosoma mansoni polycystin 1-related 0.0064 0.0175 0.0175
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0106 0.0314 0.0314
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0019
Trypanosoma brucei trypanothione reductase 0.0037 0.0085 0.0375
Echinococcus multilocularis adam 0.0016 0.0014 0.0013
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0055 0.0238
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0129 0.1775
Leishmania major hypothetical protein, conserved 0.0018 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0037
Loa Loa (eye worm) hypothetical protein 0.003 0.0059 0.0086
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0015 0.0011 0.0035
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0026 0.0047 0.06
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0118 0.0354 0.0521
Plasmodium vivax multidomain scavenger receptor, putative 0.0064 0.0175 0.2432
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0085 0.1157
Echinococcus multilocularis phd:f box containing protein 0.0035 0.0076 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Loa Loa (eye worm) hypothetical protein 0.0043 0.0104 0.0153
Toxoplasma gondii hypothetical protein 0.0107 0.0319 0.4469
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Onchocerca volvulus 0.0507 0.1655 0.6641
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Echinococcus granulosus biogenic amine 5HT receptor 0.0118 0.0354 0.0353
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0045 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0106 0.0314 0.0463
Schistosoma mansoni biogenic amine receptor 0.0118 0.0354 0.0354
Plasmodium vivax DNA repair protein REV1, putative 0.0043 0.0104 0.1429
Brugia malayi RNA, U transporter 1 0.0081 0.0231 0.0336
Loa Loa (eye worm) hypothetical protein 0.0132 0.0402 0.0593
Echinococcus granulosus 7TM GPCR rhodopsin 0.0118 0.0354 0.0353
Onchocerca volvulus 0.0096 0.028 0.1078
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0118 0.0354 0.0354
Echinococcus granulosus arachidonate 5 lipoxygenase 0.018 0.0562 0.0561
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0118 0.0354 0.0354
Loa Loa (eye worm) RecQ helicase 0.0258 0.0825 0.1218
Echinococcus granulosus leucyl aminopeptidase 0.0045 0.0109 0.0108
Onchocerca volvulus 0.0118 0.0354 0.1375
Loa Loa (eye worm) hypothetical protein 0.0046 0.0115 0.0169
Trichomonas vaginalis alpha-glucosidase, putative 0.0194 0.0611 0.1476
Trypanosoma brucei DNA damage repair protein, putative 0.0043 0.0104 0.0462
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0118 0.0354 0.0353
Echinococcus multilocularis cysteine protease 0.003 0.0059 0.0058
Echinococcus multilocularis survival motor neuron protein 1 0.0252 0.0802 0.0801
Echinococcus multilocularis cathepsin l cysteine peptidase 0.003 0.0059 0.0058
Schistosoma mansoni hypothetical protein 0.0025 0.0043 0.0043
Brugia malayi DnaJ domain containing protein 0.0134 0.041 0.0601
Schistosoma mansoni DNA helicase recq1 0.0132 0.0402 0.0402
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0016 0.0015
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0037 0.0155
Brugia malayi G-protein coupled receptor 0.0118 0.0354 0.0518
Loa Loa (eye worm) hypothetical protein 0.0072 0.0202 0.0298
Brugia malayi Cathepsin L-like precursor 0.003 0.0059 0.0082
Schistosoma mansoni cpg binding protein 0.0032 0.0068 0.0068
Trypanosoma brucei C-1-tetrahydrofolate synthase, cytoplasmic, putative 0.0017 0.0015 0.0055
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0118 0.0354 0.0353
Leishmania major alpha glucosidase II subunit, putative 0.0194 0.0611 0.2785
Echinococcus granulosus tm gpcr rhodopsin 0.0118 0.0354 0.0353
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0165 0.0512 0.1238
Echinococcus multilocularis integrin beta 2 0.0368 0.119 0.1189
Schistosoma mansoni jumonji/arid domain-containing protein 0.0133 0.0406 0.0406
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0227 0.0719 0.1062
Giardia lamblia NADH oxidase lateral transfer candidate 0.0013 0.0003 0.0008
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0224 0.0709 0.3181
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1248 0.4136 1
Brugia malayi RE15519p 0.0118 0.0354 0.0518
Brugia malayi hypothetical protein 0.0118 0.0354 0.0518
Mycobacterium ulcerans beta-lactamase 0.0106 0.0314 0.1556
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0072 0.0202 0.0763
Trypanosoma brucei glucosidase, putative 0.0194 0.0611 0.2785
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0129 0.0575
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1248 0.4136 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0059 0.0255
Loa Loa (eye worm) fibroinase 0.003 0.0059 0.0086
Schistosoma mansoni biogenic amine (5HT) receptor 0.0118 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Mycobacterium tuberculosis Probable ATP-dependent DNA helicase II UvrD2 0.0026 0.0047 0.0199
Echinococcus multilocularis allatostatin A receptor 0.0118 0.0354 0.0353
Leishmania major cathepsin L-like protease 0.003 0.0059 0.0255
Echinococcus multilocularis SAM and MBT domain containing protein 0.0095 0.0279 0.0278
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0055 0.0736
Onchocerca volvulus 0.0053 0.0139 0.0507
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0123 0.0371 0.0547
Echinococcus granulosus rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.0064
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.016 0.0784
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0045 0.0109 0.0486
Brugia malayi hypothetical protein 0.0033 0.0069 0.0097
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0139 0.0424 0.0423
Echinococcus granulosus fibrillin 1 0.0016 0.0014 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.028 0.127
Trypanosoma brucei DNA polymerase IV, putative 0.0139 0.0424 0.1931
Echinococcus granulosus rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Schistosoma mansoni importin beta-1 0.0028 0.0055 0.0055
Schistosoma mansoni alpha-1 adrenergic receptor 0.0118 0.0354 0.0354
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.028 0.028
Leishmania major importin beta-1 subunit, putative 0.0023 0.0037 0.0155
Echinococcus granulosus cathepsin l1 0.003 0.0059 0.0058
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0129 0.0575
Mycobacterium ulcerans DNA polymerase IV 0.0139 0.0424 0.2109
Echinococcus multilocularis fmrfamide receptor 0.0118 0.0354 0.0353
Echinococcus multilocularis g-protein coupled receptor 0.0118 0.0354 0.0353
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0089 0.0216
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0112 0.0271
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0036 0.0035
Echinococcus multilocularis microtubule associated protein 2 0.1518 0.504 0.504
Trypanosoma cruzi hypothetical protein, conserved 0.0194 0.0611 0.2785
Trichomonas vaginalis penicillin-binding protein, putative 0.0106 0.0314 0.0759
Trypanosoma brucei phosphoglycerate kinase 0.0061 0.0163 0.0731
Echinococcus granulosus methyl CpG binding domain protein 2 0.0021 0.0029 0.0028
Echinococcus granulosus lamin dm0 0.0053 0.0139 0.0138
Schistosoma mansoni hypothetical protein 0.1401 0.4648 0.4648
Schistosoma mansoni blooms syndrome DNA helicase 0.0067 0.0186 0.0186
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0059 0.0143
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0085 0.0245 0.109
Echinococcus granulosus neuropeptide Y receptor 0.0118 0.0354 0.0353
Echinococcus multilocularis leucyl aminopeptidase 0.0045 0.0109 0.0108
Brugia malayi hypothetical protein 0.0118 0.0354 0.0518
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0089 0.1219
Loa Loa (eye worm) G-protein coupled receptor 0.0118 0.0354 0.0521
Loa Loa (eye worm) hypothetical protein 0.0053 0.0137 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0118 0.0354 0.0354
Onchocerca volvulus 0.0118 0.0354 0.1375
Echinococcus multilocularis Polycystic kidney disease protein 0.0064 0.0175 0.0174
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0038 0.0089 0.0088
Loa Loa (eye worm) integrin beta-2 0.0397 0.1287 0.1901
Trypanosoma cruzi cysteine peptidase, putative 0.003 0.0059 0.0255
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0118 0.0354 0.0354
Onchocerca volvulus 0.0118 0.0354 0.1375
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0118 0.0354 0.0353
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0016 0.0015
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0132 0.0402 0.0401
Echinococcus multilocularis lamin dm0 0.0053 0.0139 0.0138
Brugia malayi Cathepsin L-like precursor 0.002 0.0026 0.0034
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.002 0.0026 0.0105
Schistosoma mansoni hypothetical protein 0.0402 0.1306 0.1306
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.3001 1 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.003 0.0379
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0175 0.0174
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0116 0.0349 0.0348
Plasmodium falciparum LCCL domain-containing protein 0.0064 0.0175 0.2337
Echinococcus granulosus neuropeptides capa receptor 0.0118 0.0354 0.0353
Echinococcus granulosus neuropeptide s receptor 0.0118 0.0354 0.0353
Schistosoma mansoni lamin 0.0053 0.0139 0.0139
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0663 0.2179 0.322
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0172 0.0172
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0085 0.0375
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0076 0.0331
Mycobacterium tuberculosis Conserved protein 0.0106 0.0314 0.1401
Trichomonas vaginalis alpha-glucosidase, putative 0.0194 0.0611 0.1476
Toxoplasma gondii PUL domain-containing protein 0.0037 0.0082 0.1118
Onchocerca volvulus 0.0095 0.0279 0.1072
Entamoeba histolytica recQ family helicase, putative 0.0065 0.0177 0.0402
Brugia malayi polk-prov protein 0.0043 0.0104 0.0149
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0202 0.0489
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0165 0.0512 0.7209
Mycobacterium ulcerans esterase/lipase LipP 0.0106 0.0314 0.1556
Onchocerca volvulus 0.0118 0.0354 0.1375
Echinococcus multilocularis g protein coupled receptor 0.0118 0.0354 0.0353
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0118 0.0354 0.0353
Mycobacterium tuberculosis Probable lipase LipE 0.0106 0.0314 0.1401
Echinococcus granulosus g protein coupled receptor 0.0118 0.0354 0.0353
Echinococcus multilocularis g protein coupled receptor 0.0118 0.0354 0.0353
Schistosoma mansoni hypothetical protein 0.1401 0.4648 0.4648
Schistosoma mansoni amine GPCR 0.0118 0.0354 0.0354
Onchocerca volvulus 0.003 0.0059 0.0183
Echinococcus granulosus rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1248 0.4136 1
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0003 0.0008
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0232 0.0737 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0118 0.0354 0.0354
Echinococcus multilocularis neuropeptides capa receptor 0.0118 0.0354 0.0353
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0129 0.1707
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0132 0.0402 0.0401
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.0202 0.0464
Schistosoma mansoni phd/f-box containing protein 0.0035 0.0076 0.0076
Schistosoma mansoni intermediate filament proteins 0.0053 0.0139 0.0139
Schistosoma mansoni hypothetical protein 0.0039 0.009 0.009
Schistosoma mansoni jumonji domain containing protein 0.0129 0.0393 0.0393
Echinococcus multilocularis rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0165 0.0512 0.7209
Echinococcus granulosus phosphoglycerate kinase 1 0.0165 0.0512 0.0511
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0118 0.0354 0.0353
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.016 0.016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1248 0.4136 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0118 0.0354 0.0353
Giardia lamblia Tenascin-like 0.0016 0.0014 0.0033
Leishmania major cathepsin L-like protease 0.003 0.0059 0.0255
Echinococcus granulosus RUN 0.0064 0.0175 0.0174
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0118 0.0354 0.0353
Brugia malayi larval opioid receptor 0.0118 0.0354 0.0518
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.016 0.0706
Echinococcus granulosus Smad4 0.0017 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0085 0.0246 0.0362
Leishmania major exosome subunit rrp6p homologue, putative 0.0028 0.0053 0.0225
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.028 0.0279
Onchocerca volvulus 0.0118 0.0354 0.1375
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0095 0.0279 0.1072
Loa Loa (eye worm) hypothetical protein 0.0824 0.2717 0.4015
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Onchocerca volvulus 0.003 0.0059 0.0183
Plasmodium vivax phosphoglycerate kinase, putative 0.0165 0.0512 0.7209
Schistosoma mansoni lamin 0.0053 0.0139 0.0139
Brugia malayi Kelch motif family protein 0.0075 0.0212 0.0309
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0047 0.0624
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0227 0.0719 0.0719
Schistosoma mansoni protein phosphatase 2C 0.0035 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.0071 0.0198 0.0198
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0089 0.0394
Onchocerca volvulus 0.0118 0.0354 0.1375
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0165 0.0512 0.2293
Echinococcus multilocularis Helicase RNase D C terminal, HRDC domain 0.0028 0.0053 0.0052
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0139 0.0424 0.1931
Echinococcus granulosus microtubule associated protein 2 0.1518 0.504 0.504
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Plasmodium falciparum glutathione reductase 0.0037 0.0085 0.1113
Brugia malayi intermediate filament protein 0.0053 0.0139 0.02
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0059 0.0255
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.003 0.0059 0.0086
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0194 0.0611 0.1476
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Onchocerca volvulus 0.0064 0.0175 0.0653
Echinococcus granulosus beta LACTamase domain containing family member 0.0106 0.0314 0.0313
Loa Loa (eye worm) hypothetical protein 0.0123 0.0371 0.0547
Trichomonas vaginalis phospholipase A-2-activating protein, putative 0.0025 0.0042 0.0103
Trypanosoma brucei ISWI complex protein 0.0018 0.0022 0.0085
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0085 0.0368
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.009 0.1186
Schistosoma mansoni jumonji/arid domain-containing protein 0.0133 0.0406 0.0406
Echinococcus multilocularis lamin 0.0053 0.0139 0.0138
Schistosoma mansoni growth hormone secretagogue receptor 0.0118 0.0354 0.0354
Schistosoma mansoni histamine h1 receptor 0.0118 0.0354 0.0354
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.009 0.0219
Schistosoma mansoni bromodomain containing protein 0.0082 0.0233 0.0233
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0118 0.0354 0.0521
Giardia lamblia Sgs1 DNA helicase, putative 0.0132 0.0402 0.0973
Brugia malayi Glycosyl hydrolases family 31 protein 0.0072 0.0202 0.0294
Brugia malayi WD domain containing protein 0.0037 0.0082 0.0117
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0224 0.0709 0.337
Trichomonas vaginalis penicillin-binding protein, putative 0.0106 0.0314 0.0759
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0109 0.0157
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0118 0.0354 0.0354
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Brugia malayi EGF-like domain containing protein 0.0016 0.0014 0.0015
Echinococcus multilocularis neuropeptide receptor A26 0.0118 0.0354 0.0353
Loa Loa (eye worm) hypothetical protein 0.0025 0.0043 0.0062
Echinococcus multilocularis lysosomal alpha glucosidase 0.0876 0.2891 0.2891
Echinococcus multilocularis dna polymerase kappa 0.0139 0.0424 0.0423
Loa Loa (eye worm) hypothetical protein 0.0025 0.0043 0.0062
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0112 0.0111
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0037 0.009
Echinococcus multilocularis G protein coupled receptor 139 0.0118 0.0354 0.0353
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0015 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0052 0.0136 0.0199
Brugia malayi Cathepsin L-like precursor 0.003 0.0059 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.0314 0.1425
Entamoeba histolytica hypothetical protein 0.0071 0.0198 0.0454
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0089 0.0088
Mycobacterium ulcerans lipase LipD 0.0106 0.0314 0.1556
Trypanosoma cruzi DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0116 0.0349 0.0349
Brugia malayi follicle stimulating hormone receptor 0.0343 0.1108 0.1634
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0047 0.0115
Schistosoma mansoni neuropeptide receptor 0.0118 0.0354 0.0354
Brugia malayi Serotonin receptor 0.0118 0.0354 0.0518
Leishmania major cathepsin L-like protease 0.003 0.0059 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.003 0.0059 0.0143
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0114 0.0341 0.1549
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0224 0.0709 1
Schistosoma mansoni lipoxygenase 0.0064 0.0175 0.0175
Giardia lamblia hypothetical protein 0.0016 0.0014 0.0033
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0043 0.0104 0.1429
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0059 0.0143
Mycobacterium ulcerans hypothetical protein 0.035 0.1131 0.5648
Brugia malayi Serotonin receptor 0.0118 0.0354 0.0518
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Mycobacterium leprae Probable lipase LipE 0.0106 0.0314 0.1343
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0129 0.1775
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0116 0.0349 0.0349
Loa Loa (eye worm) cysteine protease 0.003 0.0059 0.0086
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.016 0.0784
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0118 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.003 0.0043
Mycobacterium tuberculosis Conserved hypothetical protein 0.0139 0.0424 0.1898
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0118 0.0354 0.0354
Schistosoma mansoni ap endonuclease 0.0039 0.0089 0.0089
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0106 0.0314 0.1556
Trypanosoma cruzi cysteine proteinase, putative 0.0015 0.0011 0.0035
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0118 0.0354 0.0353
Trypanosoma cruzi cysteine peptidase, putative 0.003 0.0059 0.0255
Echinococcus multilocularis snurportin 1 0.0304 0.0976 0.0975
Leishmania major GTP-binding protein, putative 0.0021 0.003 0.0123
Brugia malayi mbt repeat family protein 0.0095 0.0279 0.0407
Schistosoma mansoni myelin transcription factor 1 myt1 0.0108 0.0323 0.0323
Treponema pallidum methylenetetrahydrofolate dehydrogenase (folD) 0.0017 0.0015 0.0029
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.016 0.0159
Loa Loa (eye worm) G-protein coupled receptor 0.0118 0.0354 0.0521
Schistosoma mansoni alkaline phosphatase 0.3001 1 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.0976 0.1442
Brugia malayi hypothetical protein 0.0118 0.0354 0.0518
Onchocerca volvulus 0.0118 0.0354 0.1375
Leishmania major DNA polymerase eta, putative 0.0199 0.0626 0.2858
Schistosoma mansoni hypothetical protein 0.0018 0.0022 0.0022
Entamoeba histolytica phosphoglycerate kinase, putative 0.0165 0.0512 0.1215
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0227 0.0719 0.1059
Loa Loa (eye worm) hypothetical protein 0.0106 0.0314 0.0463
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0139 0.0424 0.0424
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.0277 0.1233
Brugia malayi jmjC domain containing protein 0.0035 0.0076 0.0107
Trichomonas vaginalis DNA polymerase eta, putative 0.0139 0.0424 0.1026
Plasmodium falciparum cysteine proteinase falcipain 3 0.003 0.0059 0.0757
Brugia malayi Bromodomain containing protein 0.0096 0.028 0.041
Schistosoma mansoni jumonji domain containing protein 0.0035 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0053 0.0139 0.0204
Echinococcus multilocularis dna polymerase eta 0.0295 0.0947 0.0946
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0118 0.0354 0.0518
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0072 0.0202 0.0913
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Brugia malayi Dopamine receptor protein 1 0.0118 0.0354 0.0518
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.003 0.0123
Entamoeba histolytica hypothetical protein 0.0071 0.0198 0.0454
Brugia malayi hypothetical protein 0.0118 0.0354 0.0518
Loa Loa (eye worm) acetyltransferase 0.0147 0.0453 0.0669
Loa Loa (eye worm) hypothetical protein 0.0106 0.0314 0.0463
Toxoplasma gondii exonuclease III APE 0.0039 0.0089 0.1219
Plasmodium falciparum DNA repair protein REV1, putative 0.0043 0.0104 0.1373
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0045 0.0109 0.0486
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.011
Brugia malayi cytosol aminopeptidase 0.0045 0.0109 0.0157
Loa Loa (eye worm) melatonin receptor type 1A 0.0118 0.0354 0.0521
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0106 0.0314 0.0459
Brugia malayi Abnormal catecholamine distribution protein 1 0.2034 0.6765 1
Giardia lamblia High cysteine protein 0.0016 0.0014 0.0033
Brugia malayi Cathepsin L-like precursor 0.003 0.0059 0.0082
Onchocerca volvulus 0.0028 0.0055 0.0166
Brugia malayi Tachykinin-like peptides receptor 99D 0.0118 0.0354 0.0518
Loa Loa (eye worm) hypothetical protein 0.0165 0.0512 0.0755
Treponema pallidum phosphoglycerate kinase 0.0165 0.0512 0.1231
Echinococcus multilocularis sex peptide receptor 0.0118 0.0354 0.0353
Schistosoma mansoni phosphoglycerate kinase 0.0165 0.0512 0.0512
Echinococcus multilocularis rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.0277 0.1233
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.1306 0.1305
Loa Loa (eye worm) hypothetical protein 0.0064 0.0175 0.0257
Trypanosoma cruzi DNA polymerase eta, putative 0.0199 0.0626 0.2858
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0089 0.0088
Plasmodium falciparum cysteine proteinase falcipain 2a 0.003 0.0059 0.0757
Loa Loa (eye worm) hypothetical protein 0.0252 0.0802 0.1184
Loa Loa (eye worm) neuropeptide F receptor 0.0118 0.0354 0.0521
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0165 0.0512 0.2333
Schistosoma mansoni zinc finger protein 0.0018 0.0022 0.0022
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0118 0.0354 0.0353
Trypanosoma brucei phosphoglycerate kinase 0.0165 0.0512 0.2333
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0043 0.0104 0.1429
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0059 0.0255
Schistosoma mansoni vesicular amine transporter 0.2034 0.6765 0.6765
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0118 0.0354 0.0521
Brugia malayi Latrophilin receptor protein 2 0.0039 0.009 0.0128
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0314 0.1012 0.4628
Leishmania major phosphoglycerate kinase B, cytosolic 0.0165 0.0512 0.2333
Loa Loa (eye worm) hypothetical protein 0.0057 0.015 0.022
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0453 0.0453
Echinococcus multilocularis synaptic vesicular amine transporter 0.2034 0.6765 0.6765
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.016 0.0159
Brugia malayi Pre-SET motif family protein 0.0663 0.2179 0.3218
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0139 0.0424 0.1898
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0104 0.0462
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0314 0.1012 0.4628
Echinococcus multilocularis alkaline phosphatase 0.3001 1 1
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.016 0.2218
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0118 0.0354 0.0354
Brugia malayi Phosphoglycerate kinase 0.0061 0.0163 0.0236
Brugia malayi hypothetical protein 0.0118 0.0354 0.0518
Trichomonas vaginalis alpha-glucosidase, putative 0.0194 0.0611 0.1476
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Schistosoma mansoni alkaline phosphatase 0.3001 1 1
Toxoplasma gondii ABC1 family protein 0.0106 0.0314 0.4403
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0132 0.0402 0.059
Schistosoma mansoni biogenic amine receptor 0.0118 0.0354 0.0354
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0057 0.0056
Schistosoma mansoni cathepsin F (C01 family) 0.003 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.005 0.0129 0.0189
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0132 0.0402 0.5655
Mycobacterium tuberculosis Probable lipase LipD 0.0106 0.0314 0.1401
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0227 0.0719 0.0718
Brugia malayi latrophilin 2 splice variant baaae 0.0084 0.0241 0.0351
Toxoplasma gondii leucyl aminopeptidase LAP 0.0224 0.0709 1
Brugia malayi hypothetical protein 0.0075 0.0212 0.0309
Brugia malayi Melatonin receptor type 1A 0.0118 0.0354 0.0518
Leishmania major hypothetical protein, conserved 0.0035 0.0076 0.0331
Brugia malayi Papain family cysteine protease containing protein 0.003 0.0059 0.0082
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0118 0.0354 0.0354
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0089 0.019
Echinococcus multilocularis cathepsin L cysteine protease 0.003 0.0059 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0059 0.0143
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0202 0.0489
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0194 0.0611 0.8606
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0343 0.1108 0.1637
Echinococcus granulosus hypothetical protein 0.0118 0.0354 0.0353
Chlamydia trachomatis bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.0017 0.0015 0.0169
Giardia lamblia Fructose-bisphosphate aldolase 0.1248 0.4136 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0118 0.0354 0.0353
Echinococcus multilocularis neuropeptide s receptor 0.0118 0.0354 0.0353
Mycobacterium ulcerans phosphoglycerate kinase 0.0165 0.0512 0.2547
Brugia malayi hypothetical protein 0.0071 0.0198 0.0288
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.0314 0.1425
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1248 0.4136 1
Echinococcus multilocularis neuropeptides capa receptor 0.0118 0.0354 0.0353
Trypanosoma cruzi ribosomal RNA processing protein 6, putative 0.0028 0.0053 0.0225
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0036 0.0035
Mycobacterium tuberculosis Probable dehydrogenase 0.0085 0.0245 0.109
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0039 0.009 0.0089
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0085 0.0124
Trichomonas vaginalis esterase, putative 0.0106 0.0314 0.0759
Brugia malayi ImpB/MucB/SamB family protein 0.0139 0.0424 0.0623
Echinococcus granulosus rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0104 0.0462
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.028 0.127
Loa Loa (eye worm) hypothetical protein 0.0108 0.0323 0.0476
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0158 0.049 0.2231
Brugia malayi beta-lactamase family protein 0.0106 0.0314 0.0459
Schistosoma mansoni hypothetical protein 0.0064 0.0175 0.0175
Schistosoma mansoni amine GPCR 0.0118 0.0354 0.0354
Echinococcus granulosus Polycystic kidney disease protein 0.0064 0.0175 0.0174
Brugia malayi MH1 domain containing protein 0.0017 0.0016 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0059 0.0143
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0118 0.0354 0.0353
Trypanosoma cruzi C-1-tetrahydrofolate synthase, cytoplasmic, putative 0.0017 0.0015 0.0055
Trichomonas vaginalis hypothetical protein 0.0016 0.0014 0.0033
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0224 0.0709 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0046 0.0067
Trypanosoma cruzi cruzipain precursor, putative 0.003 0.0059 0.0255
Echinococcus granulosus peptide allatostatin:somatostatin 0.0118 0.0354 0.0353
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0194 0.0611 0.1453
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0077 0.0219 0.0218
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0085 0.0245 0.0989
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0118 0.0354 0.0353
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.163 0.5415 0.5415
Mycobacterium ulcerans ATP-dependent DNA helicase II UvrD2 0.0026 0.0047 0.0221
Brugia malayi EGF-like domain containing protein 0.0016 0.0014 0.0015
Brugia malayi putative neuropeptide receptor 0.0118 0.0354 0.0518
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Mycobacterium tuberculosis Probable reductase 0.0085 0.0245 0.109
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0085 0.0245 0.109
Toxoplasma gondii 3'-5' exonuclease domain-containing protein 0.0028 0.0053 0.0697
Brugia malayi hypothetical protein 0.0118 0.0354 0.0518
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Brugia malayi Dopamine receptor protein 2 0.0118 0.0354 0.0518
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0664 0.2183 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0093 0.0273 0.1235
Echinococcus multilocularis phospholipase A 2 activating protein 0.0037 0.0082 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Brugia malayi MH2 domain containing protein 0.0017 0.0016 0.0018
Schistosoma mansoni lipoxygenase 0.018 0.0562 0.0562
Plasmodium vivax vivapain-3 0.0015 0.0011 0.0108
Trypanosoma brucei WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0025 0.0042 0.0179
Trypanosoma cruzi cysteine protease, putative 0.0015 0.0011 0.0035
Trypanosoma cruzi cysteine proteinase, putative 0.0015 0.0011 0.0035
Echinococcus granulosus snurportin 1 0.0304 0.0976 0.0975
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0067 0.0186 0.0835
Echinococcus granulosus rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0118 0.0354 0.0518
Onchocerca volvulus 0.0118 0.0354 0.1375
Schistosoma mansoni hypothetical protein 0.0118 0.0354 0.0354
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0092 0.0266 0.0265
Schistosoma mansoni neuropeptide receptor 0.0118 0.0354 0.0354
Echinococcus granulosus rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0055 0.0238
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0118 0.0354 0.0354
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0059 0.0143
Trypanosoma cruzi ISWI complex protein 0.0018 0.0022 0.0085
Schistosoma mansoni Smad4 0.0017 0.0016 0.0016
Echinococcus multilocularis lysine specific demethylase 5A 0.0129 0.0393 0.0392
Onchocerca volvulus 0.0106 0.0314 0.1215
Onchocerca volvulus 0.0118 0.0354 0.1375
Echinococcus multilocularis jumonji domain containing 1A 0.0035 0.0076 0.0075
Echinococcus granulosus cathepsin l1 0.002 0.0026 0.0025
Schistosoma mansoni DNA polymerase eta 0.0295 0.0947 0.0947
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0129 0.1707
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0089 0.0216
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0123 0.0371 0.0544
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0383 0.1242 0.1241
Onchocerca volvulus 0.0755 0.2486 1
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0104 0.0462
Brugia malayi hypothetical protein 0.0118 0.0354 0.0518
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Brugia malayi Bloom's syndrome protein homolog 0.0258 0.0825 0.1215
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0118 0.0354 0.0354
Brugia malayi jmjC domain containing protein 0.0133 0.0406 0.0596
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0093 0.0273 0.1235
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0139 0.0424 0.0423
Schistosoma mansoni leucine aminopeptidase 0.0045 0.0109 0.0109
Schistosoma mansoni loxhd1 0.0064 0.0175 0.0175
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0106 0.0314 0.0463
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0057 0.0057
Brugia malayi G protein-coupled receptor F59B2.13 0.0118 0.0354 0.0518
Loa Loa (eye worm) hypothetical protein 0.0095 0.0279 0.0411
Mycobacterium tuberculosis Conserved protein 0.0106 0.0314 0.1401
Trypanosoma cruzi C-1-tetrahydrofolate synthase, cytoplasmic, putative 0.0017 0.0015 0.0055
Schistosoma mansoni hypothetical protein 0.0587 0.1923 0.1923
Echinococcus granulosus neuropeptide receptor 0.0118 0.0354 0.0353
Leishmania major glycosyl hydrolase-like protein 0.0072 0.0202 0.0913
Trichomonas vaginalis set domain proteins, putative 0.0755 0.2485 0.6009
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0085 0.0245 0.109
Echinococcus granulosus alkaline phosphatase 0.3001 1 1
Giardia lamblia DINP protein human, muc B family 0.0139 0.0424 0.1026
Echinococcus granulosus tm gpcr rhodopsin 0.0118 0.0354 0.0353
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0089 0.0431
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0106 0.0314 0.0314
Schistosoma mansoni opsin-like receptor 0.0118 0.0354 0.0354
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0046 0.0045
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0163 0.0731
Brugia malayi G-protein coupled receptor 0.0118 0.0354 0.0518
Trypanosoma cruzi DNA damage repair protein, putative 0.0043 0.0104 0.0462
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.0029 0.0029
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0118 0.0354 0.0353
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.028 0.028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0015 0.0011 0.0035
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0118 0.0354 0.0354
Plasmodium vivax importin-beta 2, putative 0.0028 0.0055 0.0736
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0045 0.0109 0.016
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0089 0.0394
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0089 0.1172
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1248 0.4136 1
Plasmodium falciparum thioredoxin reductase 0.0037 0.0085 0.1113
Mycobacterium leprae conserved hypothetical protein 0.0106 0.0314 0.1343
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0118 0.0354 0.0353
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0202 0.0489
Schistosoma mansoni blooms syndrome DNA helicase 0.0191 0.0599 0.0599
Brugia malayi Papain family cysteine protease containing protein 0.0015 0.0011 0.0011
Brugia malayi hypothetical protein 0.0064 0.0175 0.0254
Entamoeba histolytica deoxycytidyl transferase, putative 0.0139 0.0424 0.1002
Echinococcus granulosus lysine specific demethylase 6a 0.0035 0.0076 0.0075
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0106 0.0314 0.1401
Schistosoma mansoni sex comb on midleg homolog 0.0095 0.0279 0.0279
Schistosoma mansoni hypothetical protein 0.0134 0.041 0.041
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0011 0.0027
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0045 0.0109 0.0157
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0112 0.1537
Echinococcus granulosus dnaJ subfamily C 6 0.0134 0.041 0.0409
Loa Loa (eye worm) hypothetical protein 0.0028 0.0055 0.008
Echinococcus granulosus intermediate filament protein 0.0053 0.0139 0.0138
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0118 0.0354 0.0518
Mycobacterium tuberculosis Probable esterase LipL 0.0106 0.0314 0.1401
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0112 0.0271
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0089 0.0216
Entamoeba histolytica Ran family GTPase 0.0021 0.003 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Brugia malayi Glycosyl hydrolases family 31 protein 0.0194 0.0611 0.0898
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0056 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0059 0.0255
Leishmania major C-1-tetrahydrofolate synthase, cytoplasmic, putative 0.0017 0.0015 0.0055
Schistosoma mansoni polymyositis/scleroderma autoantigen-related 0.0028 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0075 0.0212 0.0312
Brugia malayi GnHR receptor homolog 0.0118 0.0354 0.0518
Echinococcus multilocularis dnaJ subfamily C 6 0.0134 0.041 0.0409
Plasmodium falciparum polyubiquitin binding protein, putative 0.0037 0.0082 0.1075
Trypanosoma cruzi WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0037 0.0082 0.0362
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0227 0.0719 0.0719
Loa Loa (eye worm) hypothetical protein 0.0106 0.0314 0.0463
Echinococcus granulosus SAM and MBT domain containing protein 0.0095 0.0279 0.0278
Entamoeba histolytica hypothetical protein 0.0024 0.004 0.007
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0118 0.0354 0.0353
Loa Loa (eye worm) ctsf protein 0.003 0.0059 0.0086
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Loa Loa (eye worm) 3'-5' exonuclease 0.0028 0.0053 0.0076
Schistosoma mansoni alpha glucosidase 0.0194 0.0611 0.0611
Onchocerca volvulus Cathepsin L homolog 0.003 0.0059 0.0183
Brugia malayi hypothetical protein 0.0064 0.0175 0.0254
Echinococcus multilocularis neuropeptide Y receptor 0.0118 0.0354 0.0353
Schistosoma mansoni amine GPCR 0.0118 0.0354 0.0354
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.028 0.3922
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0129 0.0575
Schistosoma mansoni opsin-like receptor 0.0118 0.0354 0.0354
Trichomonas vaginalis protein kinase inhibitor, putative 0.0134 0.041 0.099
Trypanosoma cruzi cysteine peptidase, putative 0.0015 0.0011 0.0035
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0118 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0039 0.009 0.0132
Leishmania major DNA polymerase kappa, putative 0.0043 0.0104 0.0462
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Echinococcus multilocularis rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Trichomonas vaginalis DNA helicase recq, putative 0.0158 0.049 0.1184
Trypanosoma cruzi cysteine peptidase, putative 0.003 0.0059 0.0255
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Schistosoma mansoni hypothetical protein 0.0039 0.009 0.009
Brugia malayi Cathepsin L-like precursor 0.003 0.0059 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.003 0.0073
Brugia malayi Bromodomain containing protein 0.005 0.0127 0.0182
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0087 0.0086
Echinococcus granulosus lysine specific demethylase 5A 0.0133 0.0406 0.0405
Schistosoma mansoni neuropeptide F-like receptor 0.0118 0.0354 0.0354
Echinococcus granulosus tachykinin peptides receptor 99D 0.0118 0.0354 0.0353
Echinococcus multilocularis neuropeptide receptor 0.0118 0.0354 0.0353
Brugia malayi Cathepsin L-like cysteine proteinase 0.002 0.0026 0.0034
Brugia malayi Cathepsin L-like precursor 0.003 0.0059 0.0082
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.009 0.0193
Trypanosoma brucei DNA polymerase IV, putative 0.0139 0.0424 0.1931
Brugia malayi Papain family cysteine protease containing protein 0.0015 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0489 0.1596 0.2358
Echinococcus multilocularis smad 0.0017 0.0016 0.0015
Echinococcus multilocularis beta LACTamase domain containing family member 0.0106 0.0314 0.0313
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0105 0.0104
Schistosoma mansoni phosphatidylserine receptor 0.0035 0.0076 0.0076
Onchocerca volvulus 0.003 0.0059 0.0183
Onchocerca volvulus 0.0118 0.0354 0.1375
Entamoeba histolytica hypothetical protein 0.0023 0.0037 0.0064
Brugia malayi Importin beta-1 subunit 0.0028 0.0055 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0059 0.0255
Echinococcus granulosus cathepsin L cysteine proteinase 0.003 0.0059 0.0058
Leishmania major cathepsin L-like protease 0.003 0.0059 0.0255
Loa Loa (eye worm) transcription factor SMAD2 0.0244 0.0775 0.1144
Loa Loa (eye worm) hypothetical protein 0.0025 0.0042 0.0061
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0194 0.0611 0.1453
Onchocerca volvulus 0.003 0.0059 0.0183
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Toxoplasma gondii cathepsin CPL 0.003 0.0059 0.0787
Schistosoma mansoni cpg binding protein 0.0028 0.0055 0.0055
Toxoplasma gondii thioredoxin reductase 0.0037 0.0085 0.1157
Loa Loa (eye worm) glutathione reductase 0.0037 0.0085 0.0124
Giardia lamblia Neurogenic locus notch-like protein 0.0016 0.0014 0.0033
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0167 0.0521 0.733
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0106 0.0314 0.1401
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.3001 1 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0202 0.0489
Echinococcus multilocularis g protein coupled receptor 0.0118 0.0354 0.0353
Schistosoma mansoni hypothetical protein 0.0118 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0037 0.009
Schistosoma mansoni neuropeptide receptor 0.0118 0.0354 0.0354
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0158 0.049 0.2231
Plasmodium vivax vivapain-2 0.003 0.0059 0.0787
Mycobacterium ulcerans DNA polymerase IV 0.0139 0.0424 0.2109
Schistosoma mansoni alpha-glucosidase 0.0754 0.2483 0.2483
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0089 0.0388
Schistosoma mansoni hypothetical protein 0.0304 0.0976 0.0976
Plasmodium falciparum cysteine proteinase falcipain 1 0.0015 0.0011 0.0104
Trichomonas vaginalis phospholipase A-2-activating protein, putative 0.0037 0.0082 0.0199
Echinococcus granulosus JmjC domain containing protein 4 0.0035 0.0076 0.0075
Echinococcus multilocularis GPCR, family 2 0.0039 0.009 0.0089
Brugia malayi neuropeptide F receptor 0.0118 0.0354 0.0518
Echinococcus multilocularis cathepsin l cysteine peptidase 0.003 0.0059 0.0058
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0089 0.0208
Onchocerca volvulus 0.003 0.0059 0.0183
Schistosoma mansoni alpha-glucosidase 0.0754 0.2483 0.2483
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0453 0.0665
Chlamydia trachomatis phosphoglycerate kinase 0.0165 0.0512 0.7209
Brugia malayi Phosphoglycerate kinase 0.0165 0.0512 0.0752
Echinococcus granulosus cathepsin l cysteine peptidase 0.003 0.0059 0.0058
Leishmania major cathepsin L-like protease 0.003 0.0059 0.0255
Plasmodium vivax unspecified product 0.0015 0.0011 0.0108
Loa Loa (eye worm) hypothetical protein 0.0064 0.0175 0.0257
Echinococcus multilocularis fibrillin 1 0.0024 0.0039 0.0038
Onchocerca volvulus 0.002 0.0026 0.0051
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.016 0.0784
Brugia malayi Glycosyl hydrolases family 31 protein 0.0876 0.2891 0.4271
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0118 0.0354 0.0354
Trypanosoma brucei DNA polymerase eta, putative 0.0295 0.0947 0.4327
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0118 0.0354 0.0354
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0055 0.0054
Echinococcus granulosus leucine aminopeptidase protein 0.0224 0.0709 0.0708
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0118 0.0354 0.0354
Schistosoma mansoni neuropeptide F-like receptor 0.0118 0.0354 0.0354
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0045 0.0109 0.0486
Trichomonas vaginalis DNA helicase recq1, putative 0.0258 0.0825 0.1994
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0227 0.0719 0.0718
Brugia malayi neuropeptide F receptor 0.0118 0.0354 0.0518
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0037 0.009
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0016 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0053 0.0127
Echinococcus multilocularis neutral alpha glucosidase AB 0.0194 0.0611 0.061
Plasmodium vivax JmjC domain containing protein 0.0035 0.0076 0.1023
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.011
Echinococcus multilocularis leucyl aminopeptidase 0.0045 0.0109 0.0108
Echinococcus granulosus cpg binding protein 0.0032 0.0068 0.0067
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0093 0.0273 0.1235
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.003 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1248 0.4136 1
Schistosoma mansoni amine GPCR 0.0118 0.0354 0.0354
Brugia malayi glutathione reductase 0.0037 0.0085 0.0121
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0016 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0194 0.0611 0.1476
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0089 0.0394
Echinococcus granulosus adam 0.0016 0.0014 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0194 0.0611 0.2785
Echinococcus multilocularis serotonin receptor 0.0118 0.0354 0.0353
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0227 0.0719 0.0718
Echinococcus granulosus GPCR family 2 0.0039 0.009 0.0089
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0118 0.0354 0.0353
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0132 0.0402 0.0593
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0314 0.0759
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0045 0.0109 0.0486
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0085 0.0245 0.109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0175 0.0174
Echinococcus multilocularis orexin receptor type 2 0.0118 0.0354 0.0353
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0057 0.0056
Leishmania major hypothetical protein, conserved 0.0106 0.0314 0.1425
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0118 0.0354 0.0353
Trypanosoma brucei unspecified product 0.0096 0.028 0.127
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.003 0.0379
Echinococcus granulosus lamin 0.0053 0.0139 0.0138
Echinococcus granulosus dna polymerase kappa 0.0139 0.0424 0.0423
Plasmodium falciparum JmjC domain-containing protein, putative 0.0035 0.0076 0.0983
Schistosoma mansoni phospholipase A-2-activating protein 0.0025 0.0042 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0132 0.0402 0.0401
Schistosoma mansoni phosphoglycerate kinase 0.0165 0.0512 0.0512
Schistosoma mansoni ran 0.0021 0.003 0.003
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0104 0.0462
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0037
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Echinococcus multilocularis histone acetyltransferase MYST2 0.0108 0.0323 0.0322
Onchocerca volvulus 0.0118 0.0354 0.1375
Giardia lamblia Tenascin-X 0.0016 0.0014 0.0033
Loa Loa (eye worm) hypothetical protein 0.0067 0.0186 0.0273
Brugia malayi hypothetical protein 0.005 0.0129 0.0185
Loa Loa (eye worm) papain family cysteine protease containing protein 0.003 0.0059 0.0086
Brugia malayi AKH receptor 0.0118 0.0354 0.0518
Onchocerca volvulus Cathepsin L homolog 0.003 0.0059 0.0183
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0158 0.049 0.2231
Onchocerca volvulus Cathepsin F homolog 0.003 0.0059 0.0183
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0045 0.0109 0.0486
Onchocerca volvulus 0.0064 0.0175 0.0653
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0118 0.0354 0.0353
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0035 0.0076 0.1023
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0165 0.0512 0.7208
Echinococcus granulosus histone lysine methyltransferase setb 0.0116 0.0349 0.0348
Brugia malayi Cathepsin L-like precursor 0.003 0.0059 0.0082
Brugia malayi hypothetical protein 0.0118 0.0354 0.0518
Schistosoma mansoni zinc finger protein 0.0029 0.0056 0.0056
Trypanosoma brucei unspecified product 0.0096 0.028 0.127
Schistosoma mansoni adenoreceptor 0.0118 0.0354 0.0354
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0089 0.0394
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0132 0.0402 0.5436
Echinococcus granulosus tm gpcr rhodopsin 0.0118 0.0354 0.0353
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0035 0.0076 0.0076
Echinococcus granulosus importin subunit beta 1 0.0028 0.0055 0.0054
Leishmania major hypothetical protein, conserved 0.005 0.0129 0.0575
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0165 0.0512 0.2359
Echinococcus granulosus polycomb protein SCMH1 0.0095 0.0279 0.0278
Echinococcus granulosus neuropeptide receptor A26 0.0118 0.0354 0.0353
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0076 0.011
Leishmania major cysteine peptidase A (CPA) 0.003 0.0059 0.0255
Brugia malayi MH1 domain containing protein 0.0017 0.0016 0.0018
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0106 0.0314 0.1401
Onchocerca volvulus 0.0118 0.0354 0.1375
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0314 0.0759
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.061 0.2 1
Plasmodium vivax vivapain-2 0.003 0.0059 0.0787
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0015 0.0011 0.0035
Leishmania major hypothetical protein, conserved 0.0037 0.0082 0.0362
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0059 0.0255
Echinococcus multilocularis lysosomal alpha glucosidase 0.0876 0.2891 0.2891
Trichomonas vaginalis sucrase-isomaltase, putative 0.0194 0.0611 0.1476
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0132 0.0402 0.0401
Onchocerca volvulus 0.0118 0.0354 0.1375
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0198 0.0197
Schistosoma mansoni smad1 5 8 and 0.0017 0.0016 0.0016
Brugia malayi Smad1 0.0017 0.0016 0.0018
Plasmodium falciparum cysteine proteinase falcipain 2b 0.003 0.0059 0.0757
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Plasmodium vivax vivapain-1 0.0015 0.0011 0.0108
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0089 0.0131
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0165 0.0512 0.1238
Onchocerca volvulus 0.0118 0.0354 0.1375
Trichomonas vaginalis maltase-glucoamylase, putative 0.0194 0.0611 0.1476
Entamoeba histolytica hypothetical protein 0.0071 0.0198 0.0454
Echinococcus granulosus neuropeptide FF receptor 2 0.0118 0.0354 0.0353
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0067 0.0186 0.2582
Echinococcus multilocularis rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Echinococcus multilocularis musashi 0.0053 0.0139 0.0138
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0664 0.2183 1
Brugia malayi CXXC zinc finger family protein 0.0028 0.0055 0.0076
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0067 0.0186 0.0835
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Loa Loa (eye worm) hypothetical protein 0.0116 0.0349 0.0514
Brugia malayi PHD-finger family protein 0.0035 0.0078 0.011
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0016 0.0022
Plasmodium falciparum importin beta, putative 0.0028 0.0055 0.0707
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0026 0.0037
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0163 0.0731
Echinococcus granulosus dro:myosuppressin receptor 0.0118 0.0354 0.0353
Echinococcus granulosus histone acetyltransferase MYST2 0.0108 0.0323 0.0322
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.3001 1 1
Loa Loa (eye worm) hypothetical protein 0.0106 0.0314 0.0463
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.011
Schistosoma mansoni hypothetical protein 0.1559 0.5177 0.5177
Leishmania major cathepsin L-like protease 0.003 0.0059 0.0255
Onchocerca volvulus 0.003 0.0059 0.0183
Brugia malayi mbt repeat family protein 0.0095 0.0279 0.0407
Mycobacterium tuberculosis Conserved hypothetical protein 0.035 0.1131 0.5085
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0037
Echinococcus multilocularis lysine specific demethylase 6a 0.0035 0.0076 0.0075
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0093 0.0273 0.1235
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0132 0.0402 0.5655
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0059 0.0255
Echinococcus granulosus synaptic vesicular amine transporter 0.2034 0.6765 0.6765
Trypanosoma brucei hypothetical protein, conserved 0.0106 0.0314 0.1425
Schistosoma mansoni opsin-like receptor 0.0118 0.0354 0.0354
Echinococcus multilocularis cathepsin L cysteine protease 0.003 0.0059 0.0058
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0075 0.0212 0.0312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Brugia malayi jmjC domain containing protein 0.0129 0.0393 0.0576
Echinococcus multilocularis cpg binding protein 0.0032 0.0068 0.0067
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0108 0.0323 0.0472
Echinococcus granulosus 7tm_1 domain containing protein 0.0118 0.0354 0.0353
Loa Loa (eye worm) hypothetical protein 0.0106 0.0314 0.0463
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0056 0.0081
Entamoeba histolytica recQ family DNA helicase 0.0067 0.0186 0.0423
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0118 0.0354 0.0354
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0139 0.0204
Loa Loa (eye worm) doublecortin family protein 0.0064 0.0175 0.0257
Trypanosoma brucei ribosomal RNA processing protein 6 0.0028 0.0053 0.0225
Loa Loa (eye worm) hypothetical protein 0.0295 0.0947 0.1398
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0163 0.0731
Echinococcus granulosus neuropeptides capa receptor 0.0118 0.0354 0.0353
Echinococcus granulosus cysteine protease 0.0015 0.0011 0.001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0118 0.0354 0.0354
Echinococcus granulosus lysosomal alpha glucosidase 0.0876 0.2891 0.2891
Echinococcus granulosus rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Schistosoma mansoni amine GPCR 0.0118 0.0354 0.0354
Echinococcus multilocularis phosphoglycerate kinase 1 0.0165 0.0512 0.0511
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0076 0.0331
Brugia malayi Pre-SET motif family protein 0.0096 0.028 0.0409
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0035 0.0076 0.1023
Echinococcus multilocularis fibrillin 2 0.0016 0.0014 0.0013
Schistosoma mansoni neuropeptide f receptor 76f 0.0118 0.0354 0.0354
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0021 0.0029 0.0028
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0016 0.0014 0.0033
Trypanosoma brucei aminopeptidase, putative 0.0045 0.0109 0.0486
Echinococcus multilocularis neuropeptide FF receptor 2 0.0118 0.0354 0.0353
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.0277 0.1152
Onchocerca volvulus 0.0118 0.0354 0.1375
Trichomonas vaginalis alpha-glucosidase, putative 0.0194 0.0611 0.1476
Trypanosoma cruzi ISWI complex protein 0.0018 0.0022 0.0085
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0224 0.0709 0.3236
Trypanosoma brucei DNA polymerase IV, putative 0.0139 0.0424 0.1931
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0045 0.0109 0.0157
Echinococcus multilocularis fmrfamide receptor 0.0118 0.0354 0.0353
Echinococcus granulosus neuropeptide Y receptor 0.0118 0.0354 0.0353
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0132 0.0402 0.059
Giardia lamblia Tenascin-37 0.0016 0.0014 0.0033
Echinococcus granulosus dnaJ subfamily B 0.0402 0.1306 0.1305
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0076 0.011
Schistosoma mansoni integrin beta subunit 0.0292 0.0938 0.0938
Onchocerca volvulus 0.0118 0.0354 0.1375
Echinococcus multilocularis dro:myosuppressin receptor 0.0118 0.0354 0.0353
Echinococcus granulosus g-protein coupled receptor 0.0118 0.0354 0.0353
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0175 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Echinococcus granulosus zinc finger protein 0.0029 0.0056 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0026 0.0064
Brugia malayi Doublecortin family protein 0.0064 0.0175 0.0254
Echinococcus granulosus geminin 0.1401 0.4648 0.4647
Brugia malayi F/Y-rich N-terminus family protein 0.0014 0.0008 0.0007
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0104 0.0462
Schistosoma mansoni ran 0.0021 0.003 0.003
Leishmania major trypanothione reductase 0.0037 0.0085 0.0375
Loa Loa (eye worm) beta-lactamase 0.0106 0.0314 0.0463
Echinococcus granulosus alpha 1A adrenergic receptor 0.0118 0.0354 0.0353
Onchocerca volvulus 0.0053 0.0139 0.0507
Loa Loa (eye worm) latrophilin receptor protein 2 0.0039 0.009 0.0132
Treponema pallidum ATP-dependent DNA helicase 0.0067 0.0186 0.0441
Trypanosoma brucei phosphoglycerate kinase, putative 0.0061 0.0163 0.0731
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0108 0.0323 0.0322
Mycobacterium ulcerans hypothetical protein 0.0043 0.0104 0.0505
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Giardia lamblia High cysteine protein 0.0016 0.0014 0.0033
Leishmania major DNA damage repair protein, putative 0.0043 0.0104 0.0462
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0039 0.009 0.0128
Giardia lamblia DNA damage repair protein 0.0043 0.0104 0.0252
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.028 0.127
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0089 0.1219
Echinococcus multilocularis Smad4 0.0017 0.0016 0.0015
Echinococcus granulosus biogenic amine 5HT receptor 0.0118 0.0354 0.0353
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0383 0.1242 0.1241
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0664 0.2183 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0202 0.0489
Schistosoma mansoni microtubule-associated protein tau 0.1518 0.504 0.504
Schistosoma mansoni hypothetical protein 0.0039 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0118 0.0354 0.0354
Trichomonas vaginalis maltase-glucoamylase, putative 0.0072 0.0202 0.0489
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0108 0.0323 0.0322
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0118 0.0354 0.0353
Schistosoma mansoni formate-tetrahydrofolate ligase 0.0017 0.0015 0.0015
Echinococcus granulosus fmrfamide receptor 0.0118 0.0354 0.0353
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.0043 0.0063
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0055 0.0079
Schistosoma mansoni cpg binding protein 0.0032 0.0068 0.0068
Echinococcus multilocularis G-protein coupled receptor, putative 0.0118 0.0354 0.0353
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0003 0.0002
Echinococcus granulosus bloom syndrome protein 0.0258 0.0825 0.0824
Leishmania major DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Onchocerca volvulus Neuropeptide F receptor homolog 0.0118 0.0354 0.1375
Entamoeba histolytica cysteine protease, putative 0.003 0.0059 0.0116
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0045 0.0109 0.016
Loa Loa (eye worm) WD domain-containing protein 0.0025 0.0042 0.0061
Echinococcus granulosus Helicase RNase D C terminal HRDC domain 0.0028 0.0053 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.003 0.0059 0.0143
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.061 0.2 0.9003
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0202 0.0489
Chlamydia trachomatis cytosol aminopeptidase 0.0224 0.0709 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0015 0.0011 0.0011
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0175 0.0174
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0224 0.0709 0.3236
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0065 0.0177 0.246
Loa Loa (eye worm) neuropeptide F receptor 0.0118 0.0354 0.0521
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0076 0.011
Loa Loa (eye worm) TYRA-2 protein 0.0118 0.0354 0.0521
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.016 0.0718
Brugia malayi MH2 domain containing protein 0.0017 0.0016 0.0018
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0139 0.02
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0039 0.009 0.0089
Echinococcus granulosus g protein coupled receptor 0.0118 0.0354 0.0353
Echinococcus granulosus integrin beta 2 0.0368 0.119 0.1189
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0059 0.0116
Loa Loa (eye worm) Smad1 0.0017 0.0016 0.0022
Echinococcus granulosus neuropeptide receptor 0.0118 0.0354 0.0353
Echinococcus granulosus smad 0.0017 0.0016 0.0015
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.003 0.0365
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0059 0.0143
Plasmodium vivax exosome complex exonuclease RRP6, putative 0.0028 0.0053 0.0697
Echinococcus granulosus G protein coupled receptor 139 0.0118 0.0354 0.0353
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0059 0.0143
Loa Loa (eye worm) MBCTL1 0.0108 0.0323 0.0476
Echinococcus multilocularis bloom syndrome protein 0.0258 0.0825 0.0824
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0118 0.0354 0.0521
Echinococcus multilocularis polycomb protein SCMH1 0.0095 0.0279 0.0278
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.3001 1 1
Schistosoma mansoni biogenic amine receptor 0.0118 0.0354 0.0354
Schistosoma mansoni cathepsin F (C01 family) 0.003 0.0059 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0045 0.0109 0.0109
Brugia malayi beta-lactamase family protein 0.0106 0.0314 0.0459
Brugia malayi Thioredoxin reductase 0.0037 0.0085 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0059 0.0255
Trypanosoma cruzi DNA polymerase eta, putative 0.0295 0.0947 0.4327
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0118 0.0354 0.0518
Leishmania major DNA polymerase eta, putative 0.0295 0.0947 0.4327
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0038 0.0089 0.0088
Leishmania major cathepsin L-like protease 0.003 0.0059 0.0255
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0089 0.0127
Mycobacterium tuberculosis Conserved hypothetical alanine rich protein 0.0028 0.0053 0.0222
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0077 0.0219 0.0218
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0112 0.1537
Echinococcus multilocularis protein jagged 2 0.0016 0.0014 0.0013
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0045 0.0109 0.0486
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0061 0.0163 0.0731
Trypanosoma brucei glycosyl hydrolase-like protein 0.0072 0.0202 0.0913
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Mycobacterium ulcerans hypothetical protein 0.0028 0.0053 0.0246
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0139 0.0204
Echinococcus multilocularis neuropeptide Y receptor 0.0118 0.0354 0.0353
Echinococcus multilocularis geminin 0.1401 0.4648 0.4647
Schistosoma mansoni rab6-interacting 0.0064 0.0175 0.0175
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0045 0.0109 0.0486
Echinococcus granulosus leucyl aminopeptidase 0.0045 0.0109 0.0108
Brugia malayi EGF-like domain containing protein 0.0016 0.0014 0.0015
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0003 0.0008
Brugia malayi Dopamine receptor 0.0118 0.0354 0.0518
Schistosoma mansoni survival motor neuron protein 0.0051 0.0132 0.0132
Entamoeba histolytica recQ family helicase, putative 0.0158 0.049 0.1161
Schistosoma mansoni DNA helicase recq5 0.0132 0.0402 0.0402
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0224 0.0709 0.3236
Schistosoma mansoni neuropeptide receptor 0.0118 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Echinococcus multilocularis rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Schistosoma mansoni DNA polymerase IV / kappa 0.0043 0.0104 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1248 0.4136 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0112 0.1537
Loa Loa (eye worm) jmjC domain-containing protein 0.0133 0.0406 0.0599
Loa Loa (eye worm) hypothetical protein 0.0084 0.0241 0.0355
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0105 0.0104
Plasmodium vivax SET domain protein, putative 0.0096 0.028 0.3922
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0227 0.0719 0.0718
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0016 0.0022
Echinococcus granulosus serotonin receptor 0.0118 0.0354 0.0353
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0118 0.0354 0.0518
Echinococcus granulosus jumonji domain containing 1A 0.0035 0.0076 0.0075
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0139 0.0424 0.0626
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0118 0.0354 0.0353
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0129 0.0393 0.0392
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0132 0.019
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0224 0.0709 0.3236
Giardia lamblia Phosphoglycerate kinase 0.0165 0.0512 0.1238
Schistosoma mansoni smad 0.0017 0.0016 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0118 0.0354 0.0354
Brugia malayi ImpB/MucB/SamB family protein 0.0295 0.0947 0.1395
Brugia malayi EGF-like domain containing protein 0.0016 0.0014 0.0015
Plasmodium falciparum phosphoglycerate kinase 0.0165 0.0512 0.6929
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0314 0.1012 0.4628
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0059 0.0116
Echinococcus granulosus phd:f box containing protein 0.0035 0.0076 0.0075
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0198 0.0198
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0043 0.0063
Trypanosoma brucei chrX additional, unordered contigs 0.0043 0.0104 0.0462
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1248 0.4136 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0139 0.0424 0.1026
Mycobacterium ulcerans hypothetical protein 0.0106 0.0314 0.1556
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0059 0.0255
Trypanosoma cruzi DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Trypanosoma brucei DNA damage repair protein, putative 0.0043 0.0104 0.0462
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0676 0.2221 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0123 0.0371 0.0544
Echinococcus multilocularis serotonin receptor 0.0118 0.0354 0.0353
Giardia lamblia Neurogenic locus Notch protein precursor 0.0016 0.0014 0.0033
Brugia malayi MH2 domain containing protein 0.0244 0.0775 0.1141
Trypanosoma cruzi DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0059 0.0143
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0039 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trichomonas vaginalis DNA helicase recq, putative 0.0258 0.0825 0.1994
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0059 0.0255
Giardia lamblia Tenascin precursor 0.0016 0.0014 0.0033
Echinococcus multilocularis leucyl aminopeptidase 0.0045 0.0109 0.0108
Echinococcus multilocularis zinc finger protein 0.0029 0.0056 0.0055
Echinococcus multilocularis intestinal type alkaline phosphatase 0.3001 1 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Schistosoma mansoni smad1 5 8 and 0.0017 0.0016 0.0016
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0072 0.0202 0.0913
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0165 0.0512 0.2333
Toxoplasma gondii hypothetical protein 0.0016 0.0014 0.0145
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0194 0.0611 0.0901
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Trypanosoma brucei unspecified product 0.0139 0.0424 0.1931
Onchocerca volvulus 0.0051 0.0132 0.0478
Onchocerca volvulus 0.0118 0.0354 0.1375
Brugia malayi hypothetical protein 0.0118 0.0354 0.0518
Brugia malayi hypothetical protein 0.0252 0.0802 0.1181
Echinococcus multilocularis rhodopsin orphan GPCR 0.0118 0.0354 0.0353
Echinococcus granulosus dna polymerase eta 0.0295 0.0947 0.0946
Trypanosoma brucei DNA polymerase kappa, putative 0.0139 0.0424 0.1931
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.003 0.0123
Echinococcus multilocularis cysteine protease 0.003 0.0059 0.0058
Brugia malayi jmjC domain containing protein 0.0035 0.0076 0.0107
Brugia malayi beta-lactamase 0.0106 0.0314 0.0459
Trypanosoma cruzi cysteine peptidase, putative 0.003 0.0059 0.0255
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0046 0.0045
Brugia malayi jmjC domain containing protein 0.0035 0.0076 0.0107
Brugia malayi Integrin beta pat-3 precursor 0.0397 0.1287 0.1898
Echinococcus multilocularis leucine aminopeptidase protein 0.0224 0.0709 0.0708
Loa Loa (eye worm) mbt repeat family protein 0.0095 0.0279 0.0411
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0019
Trypanosoma cruzi DNA damage repair protein, putative 0.0043 0.0104 0.0462
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0016 0.0015
Schistosoma mansoni rab6-interacting 0.0064 0.0175 0.0175
Schistosoma mansoni smad1 5 8 and 0.0017 0.0016 0.0016
Echinococcus granulosus orexin receptor type 2 0.0118 0.0354 0.0353
Echinococcus granulosus survival motor neuron protein 1 0.0252 0.0802 0.0801
Echinococcus granulosus phospholipase A 2 activating protein 0.0037 0.0082 0.0081
Loa Loa (eye worm) hypothetical protein 0.0118 0.0354 0.0521
Echinococcus granulosus fibrillin 2 0.0016 0.0014 0.0013
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0026 0.0026
Leishmania major cathepsin L-like protease 0.003 0.0059 0.0255

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 100 uM Cytotoxicity against human A431 cells after 48 hrs by trypan blue test ChEMBL. 16643063

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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