Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Niemann Pick C1 protein | 0.0106 | 0.2968 | 0.3127 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0468 | 0.1281 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0056 | 0.1364 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0066 | 0.006 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1485 | 0.1659 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0292 | 0.0101 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0015 | 0.0009 | 0.001 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0033 | 0.0606 | 0.0511 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.0209 | 0.0236 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.1485 | 0.2798 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0222 | 0.1071 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.054 | 0.0569 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0322 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0956 | 0.1007 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0106 | 0.2968 | 0.3508 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.054 | 0.0559 |
Echinococcus multilocularis | dna polymerase kappa | 0.0021 | 0.0209 | 0.022 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0033 | 0.0606 | 0.0708 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0031 | 0.054 | 0.0559 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.0085 | 0.009 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0056 | 0.1364 | 0.5 |
Schistosoma mansoni | pyruvate kinase | 0.0017 | 0.0085 | 0.009 |
Brugia malayi | CXXC zinc finger family protein | 0.0058 | 0.1404 | 0.1654 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.1723 | 0.2032 |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.0379 | 0.0438 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0222 | 0.0224 |
Leishmania major | DNA polymerase eta, putative | 0.0021 | 0.0209 | 0.011 |
Schistosoma mansoni | patched 1 | 0.0045 | 0.1009 | 0.1063 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0015 | 0.0009 | 0.001 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0033 | 0.0606 | 0.0483 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3727 | 0.3926 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.0209 | 0.0219 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0716 | 0.0755 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.0209 | 0.013 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.054 | 0.0569 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0337 | 0.0388 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.0593 | 0.0995 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0222 | 0.0123 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0716 | 0.0745 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0015 | 0.0009 | 0.001 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0031 | 0.054 | 0.0559 |
Schistosoma mansoni | nuclear hormone receptor | 0.0015 | 0.0009 | 0.001 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0045 | 0.1009 | 0.1063 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0222 | 0.1071 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0222 | 0.0049 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3727 | 0.3926 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.054 | 0.0569 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0026 | 0.0379 | 0.0281 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.2736 | 0.2875 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0716 | 0.0755 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0031 | 0.054 | 0.0569 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0056 | 0.1364 | 0.1514 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0031 | 0.054 | 0.0569 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0222 | 0.0123 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0606 | 0.063 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0055 | 0.1329 | 0.1241 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0716 | 0.0838 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0066 | 0.0067 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0026 | 0.0379 | 0.0281 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0716 | 0.0622 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0209 | 0.022 |
Mycobacterium ulcerans | pyruvate kinase | 0.0033 | 0.0606 | 0.0607 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0093 | 0.2572 | 0.3038 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0379 | 0.0389 |
Loa Loa (eye worm) | glutaminase | 0.0274 | 0.8444 | 0.8895 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0956 | 0.1007 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3727 | 0.3926 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.054 | 0.0559 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0209 | 0.011 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0033 | 0.0606 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0337 | 0.0239 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0548 | 0.0639 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0015 | 0.0009 | 0.001 |
Echinococcus multilocularis | pyruvate kinase | 0.0026 | 0.0381 | 0.0401 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0337 | 0.0239 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0056 | 0.1364 | 0.1402 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.1069 | 0.1126 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0056 | 0.1364 | 0.2554 |
Leishmania major | cytochrome p450-like protein | 0.0026 | 0.0379 | 0.0281 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0056 | 0.1364 | 0.1276 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0337 | 0.1969 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0018 | 0.0107 | 0.0115 |
Toxoplasma gondii | exonuclease III APE | 0.0056 | 0.1364 | 0.4275 |
Schistosoma mansoni | pyruvate kinase | 0.0033 | 0.0606 | 0.0639 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0031 | 0.054 | 0.0629 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0222 | 0.0016 |
Onchocerca volvulus | 0.0058 | 0.1404 | 1 | |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0468 | 0.0494 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0033 | 0.0606 | 0.0708 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0231 | 0.7052 | 0.743 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.054 | 0.0569 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0468 | 0.2997 |
Mycobacterium ulcerans | hypothetical protein | 0.017 | 0.5048 | 0.593 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0056 | 0.1364 | 0.1276 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0031 | 0.054 | 0.0569 |
Mycobacterium ulcerans | glutaminase | 0.0274 | 0.8444 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0056 | 0.1364 | 0.1606 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0129 | 0.3727 | 0.4407 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0322 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0016 | 0.0066 | 0.007 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0016 | 0.0066 | 0.007 |
Loa Loa (eye worm) | glutaminase 2 | 0.0274 | 0.8444 | 0.8895 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0337 | 0.0239 |
Brugia malayi | hypothetical protein | 0.0231 | 0.7052 | 0.835 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0379 | 0.0389 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.1009 | 0.0972 |
Echinococcus granulosus | cpg binding protein | 0.0061 | 0.1511 | 0.1592 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.7052 | 0.7427 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.054 | 0.0569 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0021 | 0.0209 | 0.011 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.2572 | 0.271 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0045 | 0.1009 | 0.1054 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0106 | 0.2968 | 1 |
Brugia malayi | cytochrome P450 | 0.0017 | 0.01 | 0.0108 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0222 | 0.0458 |
Schistosoma mansoni | hypothetical protein | 0.0307 | 0.9492 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0337 | 0.1969 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0031 | 0.054 | 0.0629 |
Loa Loa (eye worm) | histone methyltransferase | 0.0018 | 0.0114 | 0.011 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0209 | 0.011 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0031 | 0.054 | 0.0629 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.054 | 0.0629 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0031 | 0.054 | 0.0559 |
Brugia malayi | glutaminase DH11.1 | 0.0274 | 0.8444 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.1485 | 0.1564 |
Giardia lamblia | Pyruvate kinase | 0.0033 | 0.0606 | 0.4076 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.2968 | 0.3121 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0606 | 0.428 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.054 | 0.0559 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0107 | 0.3022 | 0.3183 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.0209 | 0.013 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.1723 | 0.1815 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0337 | 0.0346 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.054 | 0.0569 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0292 | 0.0101 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0548 | 0.0568 |
Echinococcus granulosus | expressed conserved protein | 0.0099 | 0.276 | 0.2908 |
Schistosoma mansoni | cpg binding protein | 0.0061 | 0.1511 | 0.1592 |
Schistosoma mansoni | cpg binding protein | 0.0058 | 0.1404 | 0.1479 |
Loa Loa (eye worm) | RNA binding protein | 0.0129 | 0.3727 | 0.392 |
Brugia malayi | CHE-14 protein | 0.0045 | 0.1009 | 0.1185 |
Schistosoma mansoni | glutaminase | 0.0274 | 0.8444 | 0.8896 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0031 | 0.054 | 0.0569 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0606 | 0.063 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0292 | 0.0194 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0015 | 0.0009 | 0.001 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0031 | 0.054 | 0.0559 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0056 | 0.1364 | 0.4185 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0066 | 0.0067 |
Loa Loa (eye worm) | cytochrome P450 | 0.0017 | 0.01 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.054 | 0.0559 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1485 | 0.1564 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0017 | 0.01 | 0.0049 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1485 | 0.1659 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0056 | 0.1364 | 0.1437 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0548 | 0.0578 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0031 | 0.054 | 0.0569 |
Echinococcus granulosus | FTZ F1 alpha | 0.0031 | 0.054 | 0.0569 |
Echinococcus granulosus | dna polymerase eta | 0.0021 | 0.0209 | 0.022 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0307 | 0.9492 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.054 | 0.0629 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Trichomonas vaginalis | glutaminase, putative | 0.0274 | 0.8444 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0152 | 0.4488 | 0.4432 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0716 | 0.0622 |
Schistosoma mansoni | coup transcription factor | 0.0031 | 0.054 | 0.0569 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0015 | 0.0009 | 0.001 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0222 | 0.0123 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0015 | 0.0009 | 0.001 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0015 | 0.0009 | 0.001 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0031 | 0.054 | 0.0629 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1485 | 0.1659 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.1069 | 0.1126 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.054 | 0.0569 |
Echinococcus multilocularis | protein dispatched 1 | 0.0052 | 0.1217 | 0.1282 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0033 | 0.0606 | 0.1023 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0016 | 0.0066 | 0.007 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0009 | 0.001 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0031 | 0.054 | 0.0559 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0058 | 0.1404 | 0.1471 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0053 | 0.0052 |
Brugia malayi | RNA binding protein | 0.0129 | 0.3727 | 0.4407 |
Leishmania major | pyruvate kinase | 0.0033 | 0.0606 | 0.0511 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0716 | 0.0755 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0151 | 0.4442 | 0.4679 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.054 | 0.0569 |
Schistosoma mansoni | cpg binding protein | 0.0061 | 0.1511 | 0.1592 |
Brugia malayi | nuclear receptor RXR | 0.0016 | 0.0066 | 0.0067 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0109 | 0.3076 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0152 | 0.4488 | 0.4432 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0468 | 0.0494 |
Echinococcus multilocularis | 0.0017 | 0.01 | 0.0106 | |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0222 | 0.0234 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0031 | 0.054 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0066 | 0.006 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.054 | 0.0629 |
Schistosoma mansoni | ran | 0.0021 | 0.0222 | 0.0234 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0337 | 0.0842 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0106 | 0.2968 | 0.3127 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0056 | 0.1364 | 0.1428 |
Schistosoma mansoni | nuclear receptor | 0.0015 | 0.0009 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0548 | 0.0578 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0026 | 0.0379 | 0.0334 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0716 | 0.0616 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Echinococcus multilocularis | tar DNA binding protein | 0.0129 | 0.3727 | 0.3926 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0031 | 0.054 | 0.0629 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0209 | 0.011 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0066 | 0.0067 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0056 | 0.1364 | 0.1276 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0015 | 0.0009 | 0.001 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0056 | 0.1364 | 0.1437 |
Brugia malayi | RNA, U transporter 1 | 0.0082 | 0.2188 | 0.2583 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0033 | 0.0606 | 0.0511 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.054 | 0.0629 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0468 | 0.0544 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0031 | 0.054 | 0.0569 |
Schistosoma mansoni | ran | 0.0021 | 0.0222 | 0.0234 |
Onchocerca volvulus | 0.0031 | 0.054 | 0.3802 | |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.0209 | 0.0219 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0222 | 0.0123 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0023 | 0.0282 | 0.0267 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.0085 | 0.009 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0716 | 0.0616 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0209 | 0.022 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0151 | 0.4442 | 0.4679 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0548 | 0.0578 |
Schistosoma mansoni | cytochrome P450 | 0.0017 | 0.01 | 0.0106 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Brugia malayi | ecdysteroid receptor | 0.0031 | 0.054 | 0.0629 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0716 | 0.0622 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.054 | 0.0629 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0129 | 0.3727 | 0.392 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0606 | 0.0639 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.2736 | 0.3232 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0031 | 0.054 | 0.0569 |
Brugia malayi | Cytochrome P450 family protein | 0.0017 | 0.01 | 0.0108 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0056 | 0.1364 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0716 | 0.0616 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0031 | 0.054 | 0.3802 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.0716 | 0.1839 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.1007 | 0.0916 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.2572 | 0.271 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.0085 | 0.009 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0066 | 0.0067 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0231 | 0.7052 | 0.743 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0031 | 0.054 | 0.3802 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.0209 | 0.0965 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.054 | 0.0569 |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.0379 | 0.0438 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.054 | 0.0629 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0031 | 0.054 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.054 | 0.0559 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0056 | 0.1364 | 1 |
Brugia malayi | TAR-binding protein | 0.0129 | 0.3727 | 0.4407 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.0085 | 0.009 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.2572 | 0.271 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Echinococcus multilocularis | expressed conserved protein | 0.0099 | 0.276 | 0.2908 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0282 | 0.0288 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0093 | 0.2572 | 0.2702 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.01 | 0.0106 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0031 | 0.054 | 0.0569 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0031 | 0.054 | 0.0559 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0292 | 0.0302 |
Schistosoma mansoni | ap endonuclease | 0.0056 | 0.1364 | 0.1437 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0023 | 0.0282 | 0.0288 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0222 | 0.0252 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0031 | 0.054 | 0.0629 |
Onchocerca volvulus | 0.0047 | 0.1069 | 0.7596 | |
Trichomonas vaginalis | ap endonuclease, putative | 0.0056 | 0.1364 | 0.1402 |
Echinococcus granulosus | tar DNA binding protein | 0.0129 | 0.3727 | 0.3926 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0292 | 0.0194 |
Echinococcus granulosus | dna polymerase kappa | 0.0021 | 0.0209 | 0.022 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0033 | 0.0606 | 0.0483 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0045 | 0.1009 | 0.1063 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0015 | 0.0009 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0548 | 0.0568 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.054 | 0.0559 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0548 | 0.0578 |
Plasmodium falciparum | pyruvate kinase | 0.0033 | 0.0606 | 0.4076 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0337 | 0.1969 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.054 | 0.0569 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0031 | 0.054 | 0.0559 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0045 | 0.1007 | 0.0916 |
Echinococcus multilocularis | dna polymerase eta | 0.0021 | 0.0209 | 0.022 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0015 | 0.0009 | 0.001 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0548 | 0.0639 |
Schistosoma mansoni | ap endonuclease | 0.0056 | 0.1364 | 0.1437 |
Schistosoma mansoni | pyruvate kinase | 0.0033 | 0.0606 | 0.0639 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0015 | 0.0009 | 0.001 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0716 | 0.211 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0031 | 0.054 | 0.0629 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0056 | 0.1364 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0066 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.2736 | 0.2875 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.054 | 0.0559 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0716 | 0.0739 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0716 | 0.0755 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3727 | 0.3926 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.1485 | 0.4679 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0956 | 0.1007 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.054 | 0.0559 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0322 | 1 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0061 | 0.1511 | 0.1592 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0606 | 0.063 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.1723 | 0.1807 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0016 | 0.0066 | 0.007 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.2572 | 0.271 |
Schistosoma mansoni | nuclear receptor | 0.0015 | 0.0009 | 0.001 |
Loa Loa (eye worm) | TAR-binding protein | 0.0129 | 0.3727 | 0.392 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.0593 | 0.9727 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0066 | 0.006 |
Echinococcus multilocularis | protein patched | 0.0045 | 0.1009 | 0.1063 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0045 | 0.1007 | 0.0916 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0548 | 0.0578 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0548 | 0.0578 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0606 | 0.428 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0222 | 0.1071 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0033 | 0.0606 | 0.1743 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.2572 | 0.271 |
Trypanosoma brucei | cytochrome P450, putative | 0.0026 | 0.0379 | 0.0281 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0122 | 0.3499 | 0.3686 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0026 | 0.0379 | 0.0389 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.054 | 0.0569 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.2572 | 0.271 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.0085 | 0.009 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0468 | 0.0494 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0016 | 0.0066 | 0.006 |
Chlamydia trachomatis | pyruvate kinase | 0.0033 | 0.0606 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0548 | 0.0578 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0017 | 0.01 | 0.0106 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.2736 | 0.3232 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0031 | 0.054 | 0.0569 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.054 | 0.0629 |
Echinococcus granulosus | pyruvate kinase | 0.0033 | 0.0606 | 0.0639 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0548 | 0.0578 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0956 | 0.1007 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0056 | 0.1364 | 1 |
Echinococcus granulosus | pyruvate kinase | 0.0033 | 0.0606 | 0.0639 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0015 | 0.0009 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.3727 | 0.3926 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0606 | 0.428 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0031 | 0.054 | 0.0629 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0021 | 0.0209 | 0.021 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0033 | 0.0606 | 0.0511 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.1485 | 0.1398 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.054 | 0.0569 |
Plasmodium vivax | pyruvate kinase, putative | 0.0033 | 0.0606 | 0.4076 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.2572 | 0.271 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.017 | 0.5048 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1485 | 0.1564 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0031 | 0.054 | 0.0569 |
Brugia malayi | steroid hormone receptor | 0.0031 | 0.054 | 0.0629 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.0209 | 0.0236 |
Brugia malayi | Cytochrome P450 family protein | 0.0074 | 0.1926 | 0.2273 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0031 | 0.054 | 0.0569 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.1485 | 0.1564 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0337 | 0.0239 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0468 | 0.0372 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0018 | 0.0114 | 0.012 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0606 | 0.0639 |
Leishmania major | pyruvate kinase | 0.0033 | 0.0606 | 0.0511 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0021 | 0.0209 | 0.022 |
Schistosoma mansoni | DNA polymerase eta | 0.0021 | 0.0209 | 0.022 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0031 | 0.054 | 0.0629 |
Trypanosoma brucei | unspecified product | 0.0021 | 0.0209 | 0.011 |
Echinococcus multilocularis | snurportin 1 | 0.0307 | 0.9492 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0015 | 0.0009 | 0.001 |
Echinococcus granulosus | snurportin 1 | 0.0307 | 0.9492 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0052 | 0.1224 | 0.3807 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.0085 | 0.009 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0045 | 0.1009 | 0.1063 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0031 | 0.054 | 0.0559 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.054 | 0.0569 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0015 | 0.0009 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.134 | 0.1404 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0222 | 0.0234 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0468 | 0.0372 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0021 | 0.0209 | 0.022 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.054 | 0.0629 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0018 | 0.0114 | 0.012 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0015 | 0.0009 | 0.001 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0548 | 0.0578 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0292 | 0.0101 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0031 | 0.054 | 0.0629 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0031 | 0.054 | 0.3802 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0033 | 0.0606 | 0.0511 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0021 | 0.0209 | 0.011 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.0209 | 0.011 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0031 | 0.054 | 0.0569 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.1007 | 0.0916 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0468 | 0.2997 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.1009 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0209 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0066 | 0.006 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0031 | 0.054 | 0.0569 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0548 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0606 | 0.063 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0716 | 0.0622 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0031 | 0.054 | 0.0569 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.1069 | 0.1256 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0074 | 0.1926 | 0.2021 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0209 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0468 | 0.0484 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0152 | 0.4488 | 0.4432 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.