Detailed information for compound 1016424

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 445.553 | Formula: C27H31N3O3
  • H donors: 1 H acceptors: 3 LogP: 2.75 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCN1C(=O)Cn2c(c3c1cccc3)c(c1c2cc(cc1)C(=O)O)C1CCCCC1)C
  • InChi: 1S/C27H31N3O3/c1-28(2)14-15-29-22-11-7-6-10-21(22)26-25(18-8-4-3-5-9-18)20-13-12-19(27(32)33)16-23(20)30(26)17-24(29)31/h6-7,10-13,16,18H,3-5,8-9,14-15,17H2,1-2H3,(H,32,33)
  • InChiKey: UPBZUQDYPCFXDY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) isoleucyl-tRNA synthetase 0.0177 0.0607 0.5791
Plasmodium falciparum isoleucine--tRNA ligase, putative 0.0177 0.0607 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0049 0.0441
Plasmodium vivax methionine--tRNA ligase, putative 0.0046 0.0089 0.1469
Schistosoma mansoni isoleucine--tRNA ligase 0.0177 0.0607 0.5071
Echinococcus multilocularis methionyl tRNA synthetase, cytoplasmic 0.0326 0.1196 1
Leishmania major valyl-tRNA synthetase, putative 0.0063 0.0155 0.2562
Leishmania major arginyl-tRNA synthetase, putative 0.0031 0.0031 0.0514
Mycobacterium ulcerans polyketide synthase associated protein PapA3 0.0031 0.0031 0.0031
Trypanosoma cruzi arginyl-tRNA synthetase, putative 0.0031 0.0031 0.0514
Plasmodium vivax valine--tRNA ligase, putative 0.0025 0.0007 0.0109
Loa Loa (eye worm) hypothetical protein 0.0025 0.0007 0.0063
Mycobacterium leprae Probable methionyl-tRNA synthase MetS 0.0046 0.0089 0.0089
Plasmodium falciparum leucine--tRNA ligase, putative 0.0025 0.0007 0.0109
Schistosoma mansoni leucyl-tRNA synthetase 0.0109 0.0337 0.2816
Trichomonas vaginalis leucyl-tRNA synthetase, putative 0.0038 0.0056 0.093
Leishmania major hypothetical protein, conserved 0.0037 0.0053 0.0877
Entamoeba histolytica valyl tRNA synthetase, putative 0.0063 0.0155 0.1404
Mycobacterium ulcerans methionyl-tRNA synthetase 0.0046 0.0089 0.0089
Trypanosoma brucei isoleucyl-tRNA synthetase, putative 0.0177 0.0607 1
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0054 0.012 0.1974
Schistosoma mansoni leucyl-tRNA synthetase 0.0025 0.0007 0.0055
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0054 0.012 0.012
Treponema pallidum valyl-tRNA synthetase 0.0063 0.0155 0.1155
Trypanosoma cruzi leucyl-tRNA synthetase, putative 0.0025 0.0007 0.0109
Loa Loa (eye worm) hypothetical protein 0.0063 0.0155 0.1484
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0054 0.012 0.1081
Onchocerca volvulus 0.0038 0.0056 0.1232
Mycobacterium ulcerans isoleucyl-tRNA synthetase 0.0177 0.0607 0.0607
Schistosoma mansoni valine-tRNA ligase 0.0063 0.0155 0.1299
Plasmodium vivax arginyl-tRNA synthetase, putative 0.0031 0.0031 0.0514
Trypanosoma cruzi valyl-tRNA synthetase, putative 0.0063 0.0155 0.2562
Mycobacterium tuberculosis Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.2556 1 1
Mycobacterium leprae Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA GLYCOSYLASE) 0.0103 0.0316 0.0316
Mycobacterium tuberculosis Isoleucyl-tRNA synthetase IleS 0.0114 0.0359 0.0359
Toxoplasma gondii pantoate-beta-alanine ligase 0.2556 1 1
Mycobacterium tuberculosis Probable valyl-tRNA synthase protein ValS (valyl-tRNA synthetase) (valine--tRNA ligase) (valine translase) 0.0063 0.0155 0.0155
Mycobacterium tuberculosis Unknown protein 0.0031 0.0031 0.0031
Trichomonas vaginalis leucyl-tRNA synthetase, putative 0.0063 0.0155 0.2562
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0061 0.0148 0.2444
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0054 0.012 0.012
Mycobacterium ulcerans pantoate--beta-alanine ligase 0.2556 1 1
Trichomonas vaginalis valyl-tRNA synthetase, putative 0.0038 0.0056 0.093
Echinococcus granulosus valyl tRNA synthetase 0.0063 0.0155 0.1299
Wolbachia endosymbiont of Brugia malayi valyl-tRNA synthetase 0.0063 0.0155 0.2159
Trypanosoma brucei valyl-tRNA synthetase, putative 0.0063 0.0155 0.2562
Loa Loa (eye worm) multisynthetase complex auxiliary component p43 0.0258 0.0926 0.8836
Brugia malayi arginyl aa-tRNA synthetase protein 1 0.0031 0.0031 0.0282
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0061 0.0148 0.2444
Mycobacterium tuberculosis Possible conserved polyketide synthase associated protein PapA2 0.0031 0.0031 0.0031
Plasmodium falciparum threonine--tRNA ligase 0.0054 0.012 0.1974
Leishmania major leucyl-tRNA synthetase, putative 0.0109 0.0337 0.5554
Entamoeba histolytica arginyl-tRNA synthetase 0.0031 0.0031 0.0282
Chlamydia trachomatis threonine--tRNA ligase 0.0061 0.0148 0.1005
Toxoplasma gondii tRNA synthetase, putative 0.0063 0.0155 0.0155
Mycobacterium ulcerans formamidopyrimidine-DNA glycosylase 0.0103 0.0316 0.0316
Echinococcus multilocularis methionine tRNA synthetase 0.0046 0.0089 0.0745
Echinococcus multilocularis isoleucyl tRNA synthetase, cytoplasmic 0.0177 0.0607 0.5071
Chlamydia trachomatis valine--tRNA ligase 0.0063 0.0155 0.1066
Echinococcus granulosus methionyl tRNA synthetase cytoplasmic 0.0326 0.1196 1
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.1139 0.4404 0.4404
Plasmodium falciparum valine--tRNA ligase, putative 0.0063 0.0155 0.2562
Trypanosoma brucei leucyl-tRNA synthetase, putative 0.0063 0.0155 0.2562
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0166 0.0564 0.5096
Onchocerca volvulus 0.0139 0.0458 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0067 0.0172 0.1646
Chlamydia trachomatis methionine--tRNA ligase 0.0326 0.1196 1
Trypanosoma brucei arginyl-tRNA synthetase, putative 0.0031 0.0031 0.0514
Trichomonas vaginalis isoleucyl, leucyl, tyrosyl, valyl and methionyl-tRNA synthetases, putative 0.0038 0.0056 0.093
Plasmodium vivax valine--tRNA ligase, putative 0.0063 0.0155 0.2562
Mycobacterium tuberculosis Conserved protein 0.0037 0.0053 0.0053
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.1429 0.5551 0.5551
Mycobacterium ulcerans arginyl-tRNA synthetase 0.0031 0.0031 0.0031
Schistosoma mansoni methyltransferase-related 0.0037 0.0053 0.0445
Mycobacterium ulcerans valyl-tRNA synthetase 0.0063 0.0155 0.0155
Loa Loa (eye worm) methionyl-tRNA synthetase 0.0046 0.0089 0.0851
Wolbachia endosymbiont of Brugia malayi isoleucyl-tRNA synthetase 0.0177 0.0607 1
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0044 0.008 0.008
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0067 0.0172 0.0172
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0054 0.012 0.012
Echinococcus multilocularis leucyl tRNA synthetase 0.0109 0.0337 0.2816
Entamoeba histolytica isoleucyl-tRNA synthetase, putative 0.0177 0.0607 0.548
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0036 0.0049 0.0049
Brugia malayi methionyl-tRNA synthetase 0.0046 0.0089 0.0805
Onchocerca volvulus 0.0067 0.0172 0.3766
Plasmodium falciparum valine--tRNA ligase, putative 0.0063 0.0155 0.2562
Toxoplasma gondii leucyl-tRNA synthetase (LeuRS2) 0.0063 0.0155 0.0155
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0067 0.0172 0.0172
Mycobacterium leprae PROBABLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA3 0.0031 0.0031 0.0031
Giardia lamblia Threonyl-tRNA synthetase 0.0054 0.012 0.1202
Trypanosoma cruzi methionyl-tRNA synthetase, putative 0.0046 0.0089 0.1469
Leishmania major methionyl-tRNA synthetase, putative 0.0046 0.0089 0.1469
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0053 0.0877
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0304 0.1107 1
Plasmodium vivax hypothetical protein, conserved 0.0109 0.0337 0.5554
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0067 0.0172 0.0172
Brugia malayi methionyl-tRNA synthetase 0.0304 0.1107 1
Mycobacterium tuberculosis Probable conserved polyketide synthase associated protein PapA3 0.0031 0.0031 0.0031
Treponema pallidum leucyl-tRNA synthetase 0.0084 0.0238 0.1921
Trypanosoma cruzi valyl-tRNA synthetase, putative 0.0025 0.0007 0.0109
Toxoplasma gondii Isoleucine-tRNA ligase 0.0025 0.0007 0.0007
Trichomonas vaginalis valyl-tRNA synthetase, putative 0.0025 0.0007 0.0109
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0583 0.2209 0.2209
Toxoplasma gondii tRNA ligases class I (M) protein 0.0046 0.0089 0.0089
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0061 0.0148 0.1239
Echinococcus granulosus arginyl tRNA synthetase cytoplasmic 0.0031 0.0031 0.0261
Echinococcus granulosus glycyl tRNA synthetase 0.0166 0.0564 0.4716
Loa Loa (eye worm) hypothetical protein 0.0084 0.0238 0.2271
Echinococcus granulosus leucyl tRNA synthetase 0.0084 0.0238 0.1987
Plasmodium falciparum leucine--tRNA ligase, putative 0.0063 0.0155 0.2562
Echinococcus multilocularis leucyl tRNA synthetase 0.0063 0.0155 0.1299
Toxoplasma gondii isoleucyl-tRNA synthetase family protein 0.0177 0.0607 0.0607
Schistosoma mansoni threonyl-tRNA synthetase 0.0049 0.0099 0.083
Mycobacterium tuberculosis Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) 0.0046 0.0089 0.0089
Mycobacterium leprae isoleucyl-tRNA synthetase IleS 0.0177 0.0607 0.0607
Treponema pallidum methionyl-tRNA synthetase 0.0304 0.1107 1
Brugia malayi valyl-tRNA synthetase family protein 0.0063 0.0155 0.1404
Mycobacterium leprae POSSIBLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA5 0.0031 0.0031 0.0031
Onchocerca volvulus 0.0067 0.0172 0.3766
Brugia malayi Methyltransferase-like protein 4 0.0037 0.0053 0.0481
Echinococcus granulosus isoleucyl trna synthetase mitochondrial 0.0139 0.0458 0.3827
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0054 0.012 0.1539
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0067 0.0172 0.0172
Trypanosoma cruzi valyl-tRNA synthetase, putative 0.0038 0.0056 0.093
Giardia lamblia Valine-tRNA ligase 0.0063 0.0155 0.1847
Loa Loa (eye worm) hypothetical protein 0.0289 0.1048 1
Mycobacterium leprae PROBABLE VALYL-tRNA SYNTHASE PROTEIN VALS (VALYL-tRNA SYNTHETASE) (VALINE--tRNA LIGASE) (VALINE TRANSLASE) ELONGS TO CLASS-I AMI 0.0063 0.0155 0.0155
Mycobacterium tuberculosis Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA glycosylase) 0.0103 0.0316 0.0316
Trichomonas vaginalis isoleucyl tRNA synthetase, putative 0.0177 0.0607 1
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.1429 0.5551 0.5551
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0061 0.0148 0.1339
Brugia malayi isoleucyl-tRNA synthetase 0.0177 0.0607 0.548
Onchocerca volvulus 0.0063 0.0155 0.3394
Loa Loa (eye worm) hypothetical protein 0.0139 0.0458 0.4371
Trypanosoma cruzi isoleucyl-tRNA synthetase, putative 0.0177 0.0607 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0007 0.0063
Brugia malayi Valyl-tRNA synthetase 0.0063 0.0155 0.1404
Mycobacterium ulcerans leucyl-tRNA synthetase 0.0084 0.0238 0.0238
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0044 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0177 0.0607 0.5791
Echinococcus granulosus valyl tRNA synthetase 0.0063 0.0155 0.1299
Plasmodium falciparum methionine--tRNA ligase 0.0046 0.0089 0.1469
Loa Loa (eye worm) VRS-2 protein 0.0025 0.0007 0.0063
Plasmodium vivax threonine--tRNA ligase, putative 0.0054 0.012 0.1974
Trichomonas vaginalis valyl-tRNA synthetase, putative 0.0025 0.0007 0.0109
Mycobacterium leprae Probable cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.1429 0.5551 0.5551
Schistosoma mansoni leucyl-tRNA synthetase 0.0025 0.0007 0.0055
Trichomonas vaginalis leucyl-tRNA synthetase, putative 0.0025 0.0007 0.0109
Trichomonas vaginalis isoleucyl, leucyl, tyrosyl, valyl and methionyl-tRNA synthetases, putative 0.0025 0.0007 0.0109
Entamoeba histolytica valyl-tRNA synthetase, putative 0.0063 0.0155 0.1404
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0009 0.0141
Schistosoma mansoni glycyl-tRNA synthetase 0.0166 0.0564 0.4716
Plasmodium vivax methionine--tRNA ligase, putative 0.0046 0.0089 0.1469
Brugia malayi isoleucyl-tRNA synthetase family protein 0.0177 0.0607 0.548
Trypanosoma cruzi leucyl-tRNA synthetase, putative 0.0063 0.0155 0.2562
Onchocerca volvulus 0.0036 0.0049 0.1066
Toxoplasma gondii isoleucyl-tRNA synthetase, putative 0.0063 0.0155 0.0155
Echinococcus granulosus Threonyl tRNA synthetase C 0.0061 0.0148 0.1239
Brugia malayi glycyl-tRNA synthetase 0.0166 0.0564 0.5096
Toxoplasma gondii leucyl-tRNA synthetase 0.0063 0.0155 0.0155
Echinococcus multilocularis valyl tRNA synthetase 0.0063 0.0155 0.1299
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0054 0.012 0.012
Wolbachia endosymbiont of Brugia malayi formamidopyrimidine-DNA glycosylase 0.0103 0.0316 0.4952
Echinococcus granulosus leucyl tRNA synthetase 0.0063 0.0155 0.1299
Mycobacterium tuberculosis Hypothetical protein 0.0037 0.0053 0.0053
Echinococcus multilocularis isoleucyl tRNA synthetase, mitochondrial 0.0139 0.0458 0.3827
Plasmodium vivax isoleucine--tRNA ligase, putative 0.0177 0.0607 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0036 0.0049 0.0441
Echinococcus multilocularis valyl tRNA synthetase 0.0063 0.0155 0.1299
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0067 0.0172 0.0172
Mycobacterium tuberculosis Possible DNA glycosylase 0.0103 0.0316 0.0316
Wolbachia endosymbiont of Brugia malayi methionyl-tRNA synthetase 0.0046 0.0089 0.1007
Giardia lamblia Isoleucyl-tRNA synthetase 0.0177 0.0607 1
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0061 0.0148 0.2444
Schistosoma mansoni valine-tRNA ligase 0.0063 0.0155 0.1299
Trichomonas vaginalis leucyl-tRNA synthetase, putative 0.0063 0.0155 0.2562
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0061 0.0148 0.1415
Brugia malayi AMP-binding enzyme family protein 0.0067 0.0172 0.1557
Leishmania major isoleucyl-tRNA synthetase, putative 0.0177 0.0607 1
Brugia malayi leucyl-tRNA synthetase 0.0063 0.0155 0.1404
Plasmodium falciparum isoleucine--tRNA ligase, putative 0.0166 0.0564 0.9296
Schistosoma mansoni methionine-tRNA synthetase 0.0326 0.1196 1
Mycobacterium tuberculosis Conserved polyketide synthase associated protein PapA1 0.0031 0.0031 0.0031
Treponema pallidum threonyl-tRNA synthetase 0.0054 0.012 0.0823
Trichomonas vaginalis valyl-tRNA synthetase, putative 0.0025 0.0007 0.0109
Loa Loa (eye worm) hypothetical protein 0.0047 0.0093 0.0887
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0153 0.0513 0.4898
Toxoplasma gondii valyl-tRNA synthetase 0.0063 0.0155 0.0155
Leishmania major threonyl-tRNA synthetase, putative 0.0061 0.0148 0.2444
Treponema pallidum isoleucyl-tRNA synthetase 0.0177 0.0607 0.5349
Loa Loa (eye worm) hypothetical protein 0.0038 0.0056 0.0538
Chlamydia trachomatis isoleucine--tRNA ligase 0.0177 0.0607 0.4939
Loa Loa (eye worm) hypothetical protein 0.0071 0.0188 0.1796
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.0049 0.0049
Giardia lamblia Leucyl-tRNA synthetase 0.0071 0.0188 0.2438
Echinococcus granulosus isoleucyl tRNA synthetase, cytoplasmic 0.0177 0.0607 0.5071
Plasmodium falciparum arginine--tRNA ligase 0.0031 0.0031 0.0514
Plasmodium falciparum methionine--tRNA ligase, putative 0.0046 0.0089 0.1469
Giardia lamblia Methionyl-tRNA synthetase 0.0046 0.0089 0.0649
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.1139 0.4404 0.4404
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0036 0.0049 0.0049
Mycobacterium tuberculosis Possible conserved polyketide synthase associated protein PapA5 0.0031 0.0031 0.0031
Trypanosoma brucei methionyl-tRNA synthetase, putative 0.0046 0.0089 0.1469
Brugia malayi protein ZK524.3 0.0071 0.0188 0.1699
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0067 0.0172 0.0172
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.1676 0.6524 0.6524
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0166 0.0564 0.5386
Chlamydia trachomatis leucine--tRNA ligase 0.0084 0.0238 0.1774
Echinococcus granulosus methionine tRNA synthetase 0.0046 0.0089 0.0745
Echinococcus multilocularis arginyl tRNA synthetase, cytoplasmic 0.0031 0.0031 0.0261
Echinococcus multilocularis glycyl tRNA synthetase 0.0166 0.0564 0.4716
Wolbachia endosymbiont of Brugia malayi leucyl-tRNA synthetase 0.0109 0.0337 0.5313
Mycobacterium ulcerans formamidopyrimidine-DNA glycosylase 0.0103 0.0316 0.0316
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0093 0.0839
Schistosoma mansoni arginyl-tRNA synthetase 0.0031 0.0031 0.0261
Trichomonas vaginalis methionine-tRNA synthetase, putative 0.0046 0.0089 0.1469
Mycobacterium ulcerans thioesterase 0.0516 0.1944 0.1944
Schistosoma mansoni isoleucine--tRNA ligase 0.0177 0.0607 0.5071
Schistosoma mansoni methionine-tRNA synthetase 0.0046 0.0089 0.0745
Entamoeba histolytica leucyl-tRNA synthetase, putative 0.0063 0.0155 0.1404
Toxoplasma gondii methionyl-tRNA synthetase 0.0061 0.0149 0.0149

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.