Detailed information for compound 1016508

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 308.431 | Formula: C19H29FO2
  • H donors: 1 H acceptors: 2 LogP: 3.59 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: F[C@@H]1CC[C@]2([C@H](C1)C(=O)C[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2O)C)C
  • InChi: 1S/C19H29FO2/c1-18-7-5-11(20)9-15(18)16(21)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h11-15,17,22H,3-10H2,1-2H3/t11-,12+,13+,14+,15-,17+,18-,19+/m1/s1
  • InChiKey: AGOFAYPOUMDRDG-XUGNFZLMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0114 0.049 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0016 0.0032 0.0032
Schistosoma mansoni neuropeptide receptor 0.0016 0.0032 0.0032
Trichomonas vaginalis glutaminase, putative 0.0277 0.1252 0.5741
Echinococcus granulosus peptide allatostatin:somatostatin 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0013 0.0016 0.0016
Echinococcus granulosus GPCR family 2 0.0062 0.0248 0.0248
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.029 0.1212
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0032 0.005
Echinococcus multilocularis cpg binding protein 0.003 0.0097 0.0097
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0016 0.0032 0.003
Schistosoma mansoni smad 0.0009 0.0001 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0089 0.0088
Onchocerca volvulus 0.0028 0.0089 0.0343
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1575 0.7332 0.7332
Schistosoma mansoni cpg binding protein 0.0028 0.0089 0.0089
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0032 0.0032
Plasmodium vivax SET domain protein, putative 0.006 0.0237 0.4582
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0124 0.0124
Trypanosoma brucei Aminopeptidase M1, putative 0.0114 0.049 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0032 0.0032
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0183 0.0183
Onchocerca volvulus 0.047 0.2156 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0101 0.1547
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0455 0.2085 1
Echinococcus multilocularis GPCR, family 2 0.0062 0.0248 0.0248
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0048 0.0072
Brugia malayi ORL1-like opioid receptor 0.0016 0.0032 0.0066
Echinococcus granulosus glycine receptor subunit beta 0.0013 0.0016 0.0016
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.029 0.1264
Schistosoma mansoni nAChR subunit 0.0013 0.0016 0.0016
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0016 0.0032 0.0073
Echinococcus granulosus pikachurin 0.0029 0.0093 0.0093
Echinococcus granulosus endonuclease exonuclease phosphatase 0.019 0.0847 0.0847
Echinococcus granulosus neurogenic locus notch protein 0.0029 0.0093 0.0093
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0217 0.1514
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0008 0.0008
Echinococcus granulosus g protein coupled receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0114 0.049 0.0489
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0127 0.2206
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.029 0.1264
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0237 0.0237
Echinococcus granulosus orexin receptor type 2 0.0016 0.0032 0.0032
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0016 0.0032 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0237 0.0237
Echinococcus multilocularis geminin 0.0503 0.2314 0.2314
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0013 0.0016 0.0016
Brugia malayi hypothetical protein 0.0016 0.0032 0.0066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0032 0.0032
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0114 0.049 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0048 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0048 0.0072
Onchocerca volvulus 0.006 0.0237 0.1031
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0013 0.0016 0.0016
Schistosoma mansoni opsin-like receptor 0.0016 0.0032 0.0032
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.003 0.0123
Mycobacterium ulcerans lipase LipD 0.0071 0.029 0.2112
Onchocerca volvulus 0.0016 0.0032 0.0073
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.0454 0.2065
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0089 0.1288
Echinococcus multilocularis mothers against decapentaplegic 5 0.0009 0.0001 0.0001
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0127 0.0127
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0127 0.0446
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0008 0.0008
Echinococcus granulosus sex peptide receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) glutaminase 0.0277 0.1252 0.1251
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0032 0.0032
Onchocerca volvulus 0.0016 0.0032 0.0073
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0016 0.0032 0.0032
Trichomonas vaginalis serine threonine-protein kinase, putative 0.0052 0.0199 0.0783
Schistosoma mansoni hypothetical protein 0.0062 0.0248 0.0248
Echinococcus granulosus 7tm_1 domain containing protein 0.0016 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0016 0.0032 0.0032
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0016 0.0032 0.0032
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0048 0.0048
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0032 0.005
Schistosoma mansoni laminin gamma-3 chain 0.0029 0.0093 0.0093
Onchocerca volvulus 0.0016 0.0032 0.0073
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.029 0.1212
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0013 0.0016 0.0015
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0068 0.0928
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0032 0.0032
Echinococcus multilocularis glycine receptor subunit beta 0.0013 0.0016 0.0016
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0013 0.0016 0.0016
Brugia malayi Peptidase family M1 containing protein 0.0114 0.049 0.107
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0071 0.029 0.0289
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0127 0.2249
Echinococcus granulosus hypothetical protein 0.0714 0.3301 0.3301
Plasmodium vivax hypothetical protein, conserved 0.0071 0.029 0.5721
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0048 0.0048
Echinococcus granulosus neuropeptide receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0013 0.0016 0.0016
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0032 0.0032
Brugia malayi G protein-coupled receptor 0.0016 0.0032 0.0066
Echinococcus granulosus allatostatin A receptor 0.0016 0.0032 0.0032
Brugia malayi latrophilin 2 splice variant baaae 0.0134 0.0585 0.1277
Echinococcus granulosus expressed protein 0.0378 0.1725 0.1725
Toxoplasma gondii aminopeptidase N protein 0.0114 0.049 1
Schistosoma mansoni nAChR subunit 0.0013 0.0016 0.0016
Leishmania major hypothetical protein, conserved 0.0071 0.029 0.5644
Brugia malayi Cation transporter family protein 0.0013 0.0016 0.0032
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0183 0.0183
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.003 0.003
Schistosoma mansoni amine GPCR 0.0016 0.0032 0.0032
Echinococcus granulosus serine:threonine protein kinase:endoribonuclease 0.0101 0.0432 0.0432
Echinococcus multilocularis somatostatin receptor 0.0016 0.0032 0.0032
Brugia malayi Cation transporter family protein 0.0013 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0114 0.049 0.049
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0175 0.0175
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0013 0.0016 0.0016
Schistosoma mansoni smad1 5 8 and 0.0009 0.0001 0.0001
Onchocerca volvulus 0.0048 0.0182 0.0778
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0013 0.0016 0.0016
Onchocerca volvulus 0.0016 0.0032 0.0073
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0183 0.0183
Echinococcus granulosus 7TM GPCR rhodopsin 0.0016 0.0032 0.0032
Schistosoma mansoni adenoreceptor 0.0016 0.0032 0.0032
Mycobacterium tuberculosis Conserved protein 0.0071 0.029 0.1264
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.029 0.1264
Brugia malayi laminin alpha chain 0.0029 0.0093 0.02
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0032 0.005
Echinococcus multilocularis tumor protein p63 0.0329 0.1498 0.1498
Schistosoma mansoni inositol monophosphatase 0.0036 0.0127 0.0127
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0032 0.005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Onchocerca volvulus 0.0114 0.049 0.2217
Trichomonas vaginalis set domain proteins, putative 0.047 0.2156 1
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0032 0.0032
Leishmania major hypothetical protein, conserved 0.0024 0.0071 0.0892
Onchocerca volvulus 0.0016 0.0032 0.0073
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0032 0.0032
Echinococcus granulosus dro:myosuppressin receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0092
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.029 0.2112
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0214 0.0465
Mycobacterium tuberculosis Conserved protein 0.0071 0.029 0.1264
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0218 0.4154
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0032 0.0172
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0127 0.2109
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0048 0.0072
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0248 0.0248
Loa Loa (eye worm) RecQ helicase 0.0041 0.0147 0.0146
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0089 0.1394
Brugia malayi Pre-SET motif family protein 0.006 0.0237 0.0514
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0032 0.0172
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0013 0.0016 0.0032
Brugia malayi hypothetical protein 0.0036 0.0124 0.0268
Brugia malayi hypothetical protein 0.0986 0.4574 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0049 0.0049
Schistosoma mansoni hypothetical protein 0.0016 0.0032 0.0032
Echinococcus granulosus TGF beta signal transducer SmadC 0.0009 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0237 0.0237
Echinococcus multilocularis g-protein coupled receptor 0.0016 0.0032 0.0032
Mycobacterium ulcerans aminopeptidase N PepN 0.0114 0.049 0.3756
Mycobacterium ulcerans beta-lactamase 0.0071 0.029 0.2112
Brugia malayi excitatory GABA receptor EXP-1A 0.0013 0.0016 0.0032
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0032 0.0032
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0214 0.0214
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0248 0.0539
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0217 0.4061
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0048 0.0101
Mycobacterium ulcerans hypothetical protein 0.0071 0.029 0.2112
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0032 0.0226
Brugia malayi Bloom's syndrome protein homolog 0.0041 0.0147 0.0319
Brugia malayi larval opioid receptor 0.0016 0.0032 0.0066
Brugia malayi Dopamine receptor protein 1 0.0016 0.0032 0.0066
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.0032 0.0032
Brugia malayi hypothetical protein 0.0016 0.0032 0.0066
Schistosoma mansoni biogenic amine receptor 0.0016 0.0032 0.0032
Echinococcus granulosus glycine receptor subunit alpha 1 0.0013 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0023
Plasmodium falciparum glutathione reductase 0.0047 0.0175 0.3146
Echinococcus granulosus g protein coupled receptor 0.0016 0.0032 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0071 0.029 0.0289
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0032 0.0032
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0114 0.049 1
Brugia malayi G-protein coupled receptor 0.0016 0.0032 0.0066
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0046
Entamoeba histolytica hypothetical protein 0.0019 0.0048 0.0551
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0032 0.0032
Echinococcus multilocularis neuropeptide receptor A26 0.0016 0.0032 0.0032
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0049 0.0105
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.007 0.1033
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Entamoeba histolytica hypothetical protein 0.0036 0.0124 0.2174
Brugia malayi Inositol-1 0.0036 0.0127 0.0275
Onchocerca volvulus 0.0016 0.0032 0.0073
Schistosoma mansoni Smad4 0.0009 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0032 0.0032
Onchocerca volvulus 0.0016 0.0032 0.0073
Schistosoma mansoni DNA helicase recq1 0.0028 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Trichomonas vaginalis DNA helicase recq, putative 0.0041 0.0147 0.054
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0048 0.0046
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0089 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0237 0.0237
Brugia malayi beta-lactamase 0.0071 0.029 0.0631
Brugia malayi hypothetical protein 0.0016 0.0032 0.0066
Schistosoma mansoni smad1 5 8 and 0.0009 0.0001 0.0001
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.0454 0.2065
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0032 0.005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0013 0.0016 0.0032
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0114 0.049 0.049
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0013 0.0016 0.0016
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0008 0.0008
Loa Loa (eye worm) TATA binding protein associated factor 0.0114 0.049 0.0489
Echinococcus multilocularis leukotriene A 4 hydrolase 0.2145 1 1
Schistosoma mansoni hypothetical protein 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0127 1
Brugia malayi GnHR receptor homolog 0.0016 0.0032 0.0066
Echinococcus granulosus serotonin receptor 0.0016 0.0032 0.0032
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0013 0.0016 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Echinococcus granulosus neuropeptide receptor 0.0016 0.0032 0.0032
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0016 0.0032 0.0032
Schistosoma mansoni neuropeptide receptor 0.0016 0.0032 0.0032
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.029 0.029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0377 0.0377
Trypanosoma cruzi aminopeptidase, putative 0.0114 0.049 1
Schistosoma mansoni nAChR subunit 0.0013 0.0016 0.0016
Echinococcus granulosus slit 2 protein 0.0029 0.0093 0.0093
Echinococcus multilocularis neuropeptide FF receptor 2 0.0016 0.0032 0.0032
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0089 0.1394
Onchocerca volvulus 0.0016 0.0032 0.0073
Schistosoma mansoni aminopeptidase A (M01 family) 0.0114 0.049 0.049
Schistosoma mansoni biogenic amine receptor 0.0016 0.0032 0.0032
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0377 0.0377
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0175 0.0175
Echinococcus multilocularis conserved hypothetical protein 0.0698 0.3226 0.3226
Echinococcus multilocularis serine:threonine protein kinase:endoribonuclease 0.0101 0.0432 0.0432
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0048 0.0046
Echinococcus multilocularis sex peptide receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0048 0.0182 0.0181
Echinococcus granulosus Smad4 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0071 0.0892
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Onchocerca volvulus 0.0016 0.0032 0.0073
Echinococcus granulosus smad 0.0009 0.0001 0.0001
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0048 0.0048
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0048 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0199 0.0783
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0032 0.0032
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.003 0.0029
Brugia malayi G-protein coupled receptor 0.0016 0.0032 0.0066
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0196 0.0876 0.0875
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0127 0.0446
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0048 0.0072
Toxoplasma gondii thioredoxin reductase 0.0047 0.0175 0.323
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0032 0.0032
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0013 0.0016 0.0016
Brugia malayi CXXC zinc finger family protein 0.0028 0.0089 0.0192
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0048 0.0101
Loa Loa (eye worm) hypothetical protein 0.0136 0.0593 0.0592
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.029 0.5698
Brugia malayi Thioredoxin reductase 0.0047 0.0175 0.038
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0013 0.0016 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Echinococcus granulosus glycine receptor subunit alpha 1 0.0013 0.0016 0.0016
Brugia malayi beta-lactamase family protein 0.0071 0.029 0.0631
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.029 0.1264
Entamoeba histolytica hypothetical protein 0.0036 0.0124 0.2174
Loa Loa (eye worm) leukotriene A4 hydrolase 0.2145 1 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.003 0.003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0071 0.029 0.0289
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0071 0.1004
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0048 0.0048
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0013 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0114 0.049 0.0489
Schistosoma mansoni hypothetical protein 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0046
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0013 0.0016 0.0016
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0175 0.3267
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0016 0.0032 0.0066
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0248 0.0248
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0009 0.0001 0.0001
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0048 0.0048
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0237 0.0237
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0217 0.0217
Entamoeba histolytica protein kinase, putative 0.0101 0.0432 0.8746
Brugia malayi Dopamine receptor 0.0016 0.0032 0.0066
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0013 0.0016 0.0016
Echinococcus granulosus cpg binding protein 0.003 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0013 0.0016 0.0016
Schistosoma mansoni glutaminase 0.0277 0.1252 0.1252
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0224 0.0224
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0032 0.0032
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0214 0.0214
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0109 0.0386
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0114 0.049 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.0032 0.0032
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0032 0.5
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0013 0.0016 0.0032
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0214 0.0214
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0071 0.1004
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0009 0.0001 0.0001
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0101 0.1697
Brugia malayi Serotonin receptor 0.0016 0.0032 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Brugia malayi mbt repeat family protein 0.0048 0.0183 0.0397
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.029 0.1212
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0049 0.0049
Echinococcus granulosus geminin 0.0503 0.2314 0.2314
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0029 0.0093 0.02
Schistosoma mansoni nAChR subunit 0.0013 0.0016 0.0016
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.029 0.2112
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0013 0.0016 0.0032
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0048 0.0101
Loa Loa (eye worm) abnormal epIthelia family member 0.0029 0.0093 0.0092
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0013 0.0016 0.0015
Onchocerca volvulus 0.0071 0.029 0.128
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0114 0.049 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0032 0.0032
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0032 0.0172
Schistosoma mansoni amine GPCR 0.0016 0.0032 0.0032
Echinococcus multilocularis serotonin receptor 0.0136 0.0593 0.0593
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0048 0.0048
Loa Loa (eye worm) IRE protein kinase 0.0101 0.0432 0.043
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0016 0.0032 0.003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0377 0.0377
Brugia malayi hypothetical protein 0.0016 0.0032 0.0066
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0013 0.0016 0.0032
Echinococcus multilocularis pikachurin 0.0029 0.0093 0.0093
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0032 0.0032
Trypanosoma brucei trypanothione reductase 0.0047 0.0175 0.3146
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0214 0.0214
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0032 0.0172
Schistosoma mansoni neuropeptide receptor 0.0016 0.0032 0.0032
Onchocerca volvulus Neuropeptide F receptor homolog 0.0016 0.0032 0.0073
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0377 0.0822
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0013 0.0016 0.0032
Schistosoma mansoni DNA helicase recq5 0.0028 0.0089 0.0089
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.029 0.5698
Echinococcus multilocularis orexin receptor type 2 0.0016 0.0032 0.0032
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0013 0.0016 0.0032
Schistosoma mansoni smad1 5 8 and 0.0009 0.0001 0.0001
Schistosoma mansoni myosin xvIII 0.0016 0.0032 0.0032
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0114 0.049 1
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0032 0.0032
Brugia malayi hypothetical protein 0.0016 0.0032 0.0066
Schistosoma mansoni biogenic amine receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.02 0.0198
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0114 0.049 0.049
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0377 0.0377
Entamoeba histolytica recQ family DNA helicase 0.0014 0.0024 0.0055
Entamoeba histolytica hypothetical protein 0.0019 0.0048 0.0551
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0032 0.0032
Brugia malayi glutathione reductase 0.0047 0.0175 0.038
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0127 0.0446
Mycobacterium ulcerans glutaminase 0.0277 0.1252 1
Loa Loa (eye worm) glutathione reductase 0.0047 0.0175 0.0174
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0016 0.0032 0.0066
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.003 0.0123
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0032 0.0032
Schistosoma mansoni opsin-like receptor 0.0016 0.0032 0.0032
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0071 0.0892
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.008 0.008
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.0454 0.2065
Echinococcus granulosus glycine receptor subunit alpha 1 0.0013 0.0016 0.0016
Brugia malayi laminin-like protein K08C7.3 precursor 0.0029 0.0093 0.02
Schistosoma mansoni hypothetical protein 0.0062 0.0248 0.0248
Brugia malayi G protein-coupled receptor F59B2.13 0.0016 0.0032 0.0066
Loa Loa (eye worm) hypothetical protein 0.0196 0.0876 0.0875
Brugia malayi Pre-SET motif family protein 0.0413 0.189 0.4129
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.003 0.0177
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Echinococcus multilocularis Smad4 0.0009 0.0001 0.0001
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0182 0.0182
Echinococcus multilocularis G protein coupled receptor 139 0.0016 0.0032 0.0032
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0048 0.0101
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0114 0.049 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0032 0.0172
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0071 0.029 0.0289
Echinococcus multilocularis neurogenic locus notch protein 0.0029 0.0093 0.0093
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0013 0.0016 0.0016
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0016 0.0032 0.0032
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Schistosoma mansoni hypothetical protein 0.0036 0.0124 0.0124
Brugia malayi hypothetical protein 0.0114 0.049 0.107
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0217 0.0472
Schistosoma mansoni growth hormone secretagogue receptor 0.0016 0.0032 0.0032
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0048 0.0072
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0013 0.0016 0.0015
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0071 0.1053
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0114 0.049 0.049
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0048 0.0048
Brugia malayi hypothetical protein 0.0016 0.0032 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Schistosoma mansoni cell polarity protein 0.0029 0.0093 0.0093
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0032 0.0032
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0089 0.0089
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0048 0.0048
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0114 0.049 0.049
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0032 0.005
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0016 0.0032 0.0032
Schistosoma mansoni opsin-like receptor 0.0016 0.0032 0.0032
Brugia malayi beta-lactamase family protein 0.0071 0.029 0.0631
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.051 0.2335
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Echinococcus granulosus g protein coupled receptor 0.0016 0.0032 0.0032
Brugia malayi neuropeptide F receptor 0.0016 0.0032 0.0066
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0013 0.0016 0.0016
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0012 0.0024
Loa Loa (eye worm) LGC-31 protein 0.0013 0.0016 0.0015
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0016 0.0032 0.0032
Schistosoma mansoni cpg binding protein 0.003 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0046
Onchocerca volvulus 0.0016 0.0032 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0048 0.0072
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.2145 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0032 0.003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0013 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0027 0.0082 0.0081
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0032 0.005
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0413 0.189 0.1888
Onchocerca volvulus 0.0016 0.0032 0.0073
Loa Loa (eye worm) beta-lactamase 0.0071 0.029 0.0289
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0114 0.049 0.049
Brugia malayi hypothetical protein 0.0024 0.0071 0.0153
Brugia malayi PXA domain containing protein 0.0019 0.0048 0.0101
Onchocerca volvulus 0.0016 0.0032 0.0073
Echinococcus granulosus fmrfamide receptor 0.0016 0.0032 0.0032
Brugia malayi isocitrate dehydrogenase 0.0016 0.003 0.0063
Onchocerca volvulus 0.0114 0.049 0.2217
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.019 0.0847 0.0847
Leishmania major trypanothione reductase 0.0047 0.0175 0.3146
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0377 0.0377
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0016 0.0032 0.0032
Echinococcus granulosus neuropeptide FF receptor 2 0.0016 0.0032 0.0032
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0016 0.0032 0.003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0032 0.0172
Echinococcus granulosus glycine receptor subunit beta 0.0013 0.0016 0.0016
Echinococcus granulosus nAChR subunit 0.0013 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0028 0.0089 0.0088
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0217 0.091
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0032 0.005
Loa Loa (eye worm) hypothetical protein 0.0136 0.0593 0.0592
Echinococcus multilocularis neuropeptide s receptor 0.0016 0.0032 0.0032
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0032 0.0032
Brugia malayi putative neuropeptide receptor 0.0016 0.0032 0.0066
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.006 0.0237 0.0235
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0183 0.0183
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0016 0.0032 0.0032
Onchocerca volvulus 0.0016 0.0032 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0016 0.0032 0.0032
Brugia malayi Tachykinin-like peptides receptor 99D 0.0016 0.0032 0.0066
Brugia malayi Peptidase family M1 containing protein 0.0114 0.049 0.107
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0183 0.078
Loa Loa (eye worm) hypothetical protein 0.0048 0.0183 0.0182
Entamoeba histolytica hypothetical protein 0.0036 0.0124 0.2174
Mycobacterium tuberculosis Probable reductase 0.0106 0.0454 0.2065
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0248 0.0248
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0032 0.003
Echinococcus granulosus G protein coupled receptor 139 0.0016 0.0032 0.0032
Echinococcus granulosus tumor protein p63 0.0329 0.1498 0.1498
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0124 0.0124
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0127 0.2206
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.003 0.003
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0048 0.0046
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0049 0.0048
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0048 0.0048
Brugia malayi hypothetical protein 0.0019 0.0048 0.0101
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0127 0.0127
Entamoeba histolytica aminopeptidase, putative 0.0114 0.049 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0237 0.0237
Brugia malayi Calcitonin receptor-like protein seb-1 0.0196 0.0876 0.1913
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0183 0.0183
Schistosoma mansoni nAChR subunit 0.0013 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0293 0.133 0.133
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.029 0.1212
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.0454 0.8614
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0248 0.0246
Brugia malayi hypothetical protein 0.0016 0.0031 0.0064
Brugia malayi Ribonuclease 2-5A family protein 0.0101 0.0432 0.0941
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0071 0.029 0.0289
Loa Loa (eye worm) hypothetical protein 0.0134 0.0585 0.0584
Entamoeba histolytica hypothetical protein 0.0036 0.0124 0.2174
Loa Loa (eye worm) ACC-1 protein 0.0013 0.0016 0.0015
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0175 0.323
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0013 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0032 0.0032
Brugia malayi neuropeptide F receptor 0.0016 0.0032 0.0066
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0114 0.049 0.049
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.029 0.5644
Brugia malayi MH2 domain containing protein 0.0139 0.061 0.133
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0237 0.0237
Brugia malayi PXA domain containing protein 0.0019 0.0048 0.0101
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0248 0.0539
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0013 0.0016 0.0032
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.029 0.029
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.003 0.0123
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0124 0.0124
Echinococcus multilocularis nAChR subunit 0.0013 0.0016 0.0016
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0196 0.0876 0.1913
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0114 0.049 1
Brugia malayi TATA binding protein associated factor 0.0114 0.049 0.107
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0032 0.0172
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0032 0.0068
Loa Loa (eye worm) transcription factor SMAD2 0.0139 0.061 0.0608
Schistosoma mansoni hypothetical protein 0.0062 0.0248 0.0248
Onchocerca volvulus 0.0071 0.029 0.128
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0016 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.051 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0217 0.1514
Plasmodium falciparum thioredoxin reductase 0.0047 0.0175 0.3146
Echinococcus multilocularis expressed protein 0.0378 0.1725 0.1725
Echinococcus granulosus bloom syndrome protein 0.0041 0.0147 0.0147
Onchocerca volvulus 0.0016 0.0032 0.0073
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0114 0.049 1
Brugia malayi hypothetical protein 0.0114 0.049 0.107
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0377 0.0376
Loa Loa (eye worm) peptidase family M1 containing protein 0.0114 0.049 0.0489
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0214 0.0214
Treponema pallidum NADH oxidase 0.0016 0.0032 1
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0114 0.049 0.2157
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0012 0.0024
Echinococcus granulosus neuropeptide s receptor 0.0016 0.0032 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Schistosoma mansoni slit 0.0029 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0092
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.0454 0.2065
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0114 0.049 0.049
Loa Loa (eye worm) ACC-1 protein 0.0013 0.0016 0.0015
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0032 0.0032
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0032 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Echinococcus multilocularis allatostatin A receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0101 0.1651
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.029 0.0289
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0048 0.0048
Brugia malayi EGF-like domain containing protein 0.0029 0.0093 0.02
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0016 0.0032 0.0066
Echinococcus granulosus alpha 1A adrenergic receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0055 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0175 0.0174
Plasmodium falciparum thioredoxin reductase 0.0016 0.0032 0.005
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0089 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0032 0.0032
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0032 0.0032
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0114 0.049 0.049
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0071 0.0892
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0029 0.0093 0.0093
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.029 0.1264
Loa Loa (eye worm) hypothetical protein 0.0114 0.049 0.0489
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0071 0.1004
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0016 0.0032 0.0032
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0089 0.0193
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0016 0.0032 0.0066
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Echinococcus granulosus mothers against decapentaplegic 5 0.0009 0.0001 0.0001
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0013 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0048 0.0048
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0114 0.049 0.049
Loa Loa (eye worm) inositol-1 0.0036 0.0127 0.0126
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.029 0.0631
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0127 0.2206
Brugia malayi follicle stimulating hormone receptor 0.0016 0.0032 0.0066
Schistosoma mansoni hypothetical protein 0.0062 0.0248 0.0248
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0008 0.0013
Toxoplasma gondii ABC1 family protein 0.0071 0.029 0.5698
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.003 0.0123
Trichomonas vaginalis DNA helicase recq1, putative 0.0041 0.0147 0.054
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0013 0.0016 0.0032
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0114 0.049 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0032 0.0032
Onchocerca volvulus 0.0016 0.0032 0.0073
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.051 0.2335
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0089 0.0088
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0114 0.049 0.049
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.029 0.1212
Echinococcus granulosus somatostatin receptor 0.0016 0.0032 0.0032
Brugia malayi AKH receptor 0.0016 0.0032 0.0066
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0183 0.0183
Brugia malayi mbt repeat family protein 0.0048 0.0183 0.0397
Loa Loa (eye worm) hypothetical protein 0.0029 0.0093 0.0092
Echinococcus multilocularis smad 0.0009 0.0001 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0032 0.0032
Schistosoma mansoni blooms syndrome DNA helicase 0.0014 0.0024 0.0024
Schistosoma mansoni nAChR subunit 0.0013 0.0016 0.0016
Trypanosoma brucei Aminopeptidase M1, putative 0.0114 0.049 1
Brugia malayi Cation transporter family protein 0.0013 0.0016 0.0032
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0048 0.0048
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0377 0.0377
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0013 0.0016 0.0015
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0048 0.0048
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0032 0.0172
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0048 0.0048
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0013 0.0016 0.0032
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0032 0.0032
Onchocerca volvulus 0.0048 0.0183 0.078
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0237 0.4552
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0016 0.0032 0.0032
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0013 0.0016 0.0016
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Onchocerca volvulus 0.0016 0.0032 0.0073
Schistosoma mansoni inositol monophosphatase 0.0036 0.0127 0.0127
Trypanosoma brucei aminopeptidase, putative 0.0114 0.049 1
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0183 0.0182
Brugia malayi hypothetical protein 0.0016 0.0032 0.0066
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Echinococcus granulosus neuropeptide receptor A26 0.0016 0.0032 0.0032
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0175 0.0705
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0032 0.005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0046
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0114 0.049 0.049
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0032 0.0032
Brugia malayi hypothetical protein 0.0016 0.0032 0.0066
Toxoplasma gondii aminopeptidase N, putative 0.0114 0.049 1
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0114 0.049 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0377 0.0377
Loa Loa (eye worm) hypothetical protein 0.0062 0.0248 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0048 0.0072
Brugia malayi hypothetical protein 0.0016 0.0032 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0032 0.0172
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0114 0.049 0.049
Plasmodium vivax glutathione reductase, putative 0.0047 0.0175 0.3267
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0016 0.0032 0.0066
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0013 0.0016 0.0016
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0217 0.0217
Echinococcus granulosus aminopeptidase N 0.0114 0.049 0.049
Echinococcus multilocularis aminopeptidase N 0.0114 0.049 0.049
Onchocerca volvulus 0.0016 0.0032 0.0073
Schistosoma mansoni nAChR subunit 0.0013 0.0016 0.0016
Brugia malayi Isocitrate dehydrogenase 0.0016 0.003 0.0063
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0013 0.0016 0.0016
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0032 0.0032
Schistosoma mansoni histamine h1 receptor 0.0016 0.0032 0.0032
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0114 0.049 1
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0048 0.0048
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0016 0.0032 0.0032
Echinococcus multilocularis glycine receptor subunit beta 0.0013 0.0016 0.0016
Trypanosoma cruzi aminopeptidase, putative 0.0114 0.049 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0048 0.0048
Mycobacterium leprae Probable lipase LipE 0.0071 0.029 0.4509
Brugia malayi Peptidase family M1 containing protein 0.0114 0.049 0.107
Onchocerca volvulus 0.0071 0.029 0.128
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0032 0.0032
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0032 0.0011
Brugia malayi Serotonin receptor 0.0016 0.0032 0.0066
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Schistosoma mansoni cpg binding protein 0.003 0.0097 0.0097
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0032 0.0032
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0183 0.0183
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Schistosoma mansoni neuropeptide receptor 0.0016 0.0032 0.0032
Brugia malayi putative neuropeptide receptor NPR1 0.0016 0.0032 0.0066
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0013 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Trichomonas vaginalis esterase, putative 0.0071 0.029 0.1212
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.051 0.2335
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0048 0.0101
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0013 0.0016 0.0032
Schistosoma mansoni neuropeptide f receptor 76f 0.0016 0.0032 0.0032
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0114 0.049 0.049
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0032 0.0032
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0089 0.0193
Loa Loa (eye worm) MH2 domain-containing protein 0.0139 0.061 0.0608
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0048 0.0048
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0089 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0032 0.0032
Brugia malayi hypothetical protein 0.0016 0.0032 0.0066
Plasmodium falciparum glutathione reductase 0.0016 0.0032 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0071 0.007
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0127 0.2109
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0032 0.005
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0013 0.0016 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0032 0.0032
Loa Loa (eye worm) aminopeptidase N 0.0114 0.049 0.0489
Schistosoma mansoni hypothetical protein 0.0503 0.2314 0.2314
Loa Loa (eye worm) hypothetical protein 0.0071 0.029 0.0289
Entamoeba histolytica protein kinase, putative 0.0101 0.0432 0.8746
Echinococcus multilocularis dro:myosuppressin receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) TYRA-2 protein 0.0016 0.0032 0.003
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0013 0.0016 0.0016
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0032 0.0032
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0048 0.0048
Brugia malayi glutaminase DH11.1 0.0277 0.1252 0.2734
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.0454 0.2065
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0101 0.1547
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.003 0.003
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0114 0.049 0.049
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) MBCTL1 0.0055 0.0214 0.0213
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Schistosoma mansoni biogenic amine (5HT) receptor 0.0136 0.0593 0.0593
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0135 0.2283
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0248 0.0248
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0114 0.049 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.029 0.029
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0013 0.0016 0.0016
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0217 0.0217
Onchocerca volvulus 0.0114 0.049 0.2217
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.003
Mycobacterium tuberculosis Conserved protein 0.0071 0.029 0.1264
Echinococcus granulosus biogenic amine 5HT receptor 0.0136 0.0593 0.0593
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.029 0.029
Toxoplasma gondii aminopeptidase n, putative 0.0114 0.049 1
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0032 0.0172
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Brugia malayi Dopamine receptor protein 2 0.0016 0.0032 0.0066
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0048 0.0048
Schistosoma mansoni hypothetical protein 0.0134 0.0585 0.0585
Mycobacterium leprae conserved hypothetical protein 0.0071 0.029 0.4509
Mycobacterium ulcerans aminopeptidase N PepN 0.0114 0.049 0.3756
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0032 0.0032
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0049 0.0048
Schistosoma mansoni amine GPCR 0.0016 0.0032 0.0032
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0016 0.0032 0.0032
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0008 0.0007
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0048 0.0048
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0032 0.0032
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0101 0.0324
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0032 0.0032
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0013 0.0016 0.0015
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0032 0.003
Schistosoma mansoni amine GPCR 0.0016 0.0032 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0032 0.0172
Echinococcus multilocularis bloom syndrome protein 0.0041 0.0147 0.0147
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0048 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0049 0.0049
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0127 0.0777
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0013 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0016 0.0032 0.0032
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0048 0.0048
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0114 0.049 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0016 0.0032 0.003
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0032 0.0032
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0049 0.0049
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0048 0.0048
Echinococcus multilocularis slit 2 protein 0.0029 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0046
Echinococcus granulosus tachykinin peptides receptor 99D 0.0016 0.0032 0.0032
Loa Loa (eye worm) glutaminase 2 0.0277 0.1252 0.1251
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0013 0.0016 0.0016
Echinococcus multilocularis serotonin receptor 0.0136 0.0593 0.0593
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Brugia malayi RE15519p 0.0016 0.0032 0.0066
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0032 0.0226
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.029 0.1264
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0114 0.049 0.2157
Echinococcus granulosus g-protein coupled receptor 0.0016 0.0032 0.0032
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.029 0.1264
Schistosoma mansoni hypothetical protein 0.0503 0.2314 0.2314
Schistosoma mansoni amine GPCR 0.0016 0.0032 0.0032
Schistosoma mansoni alpha-1 adrenergic receptor 0.0016 0.0032 0.0032
Brugia malayi sulfakinin receptor protein 0.0016 0.0032 0.0066
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0089 0.0089
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0114 0.049 0.2157
Loa Loa (eye worm) melatonin receptor type 1A 0.0016 0.0032 0.003
Trypanosoma cruzi Aminopeptidase M1, putative 0.0114 0.049 1
Brugia malayi Melatonin receptor type 1A 0.0016 0.0032 0.0066
Entamoeba histolytica hypothetical protein 0.0019 0.0048 0.0551
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0046
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0013 0.0016 0.0032
Brugia malayi hypothetical protein 0.0019 0.0048 0.0101

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 50 uM Cytotoxicity against human CEM cells assessed as cell survival after 72 hrs by calcein-AM assay ChEMBL. 18557605
IC50 (functional) > 50 uM Cytotoxicity against human MCF7 cells assessed as cell survival after 72 hrs by calcein-AM assay ChEMBL. 18557605
IC50 (functional) > 50 uM Cytotoxicity against human RPMI 8226 cells assessed as cell survival after 72 hrs by calcein-AM assay ChEMBL. 18557605
IC50 (ADMET) > 50 uM Cytotoxicity against human BJ cells assessed as cell survival after 72 hrs by calcein-AM assay ChEMBL. 18557605

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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