TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 354.36 | Formula: C18H18N4O4
H donors: 0 H acceptors: 3 LogP: 0.8 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: O=C1N(COc2c1cc1OC3CCCN3C(=O)c1c2)CCn1cncc1
InChi: 1S/C18H18N4O4/c23-17-12-9-15-13(18(24)22-4-1-2-16(22)26-15)8-14(12)25-11-21(17)7-6-20-5-3-19-10-20/h3,5,8-10,16H,1-2,4,6-7,11H2
InChiKey: SRKMAEMHNMOCFY-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	sex peptide receptor	0.011	0.0154	0.0199
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0196	0.0496	0.0496
Trichomonas vaginalis	cyclin D, putative	0.0076	0.0021	0.0013
Brugia malayi	Tachykinin-like peptides receptor 99D	0.011	0.0154	0.0154
Echinococcus multilocularis	neuropeptide receptor A26	0.011	0.0154	0.0199
Echinococcus multilocularis	epidermal growth factor receptor	0.0391	0.1268	0.1642
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.011	0.0154	0.0154
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.2593	1	1
Loa Loa (eye worm)	hypothetical protein	0.0196	0.0496	0.0496
Schistosoma mansoni	site-1 peptidase (S08 family)	0.0127	0.0222	0.0222
Trichomonas vaginalis	cyclin B, putative	0.0076	0.0021	0.0013
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Toxoplasma gondii	subtilisin SUB2	0.0127	0.0222	0.4914
Plasmodium falciparum	dipeptidyl aminopeptidase 3	0.0169	0.0389	1
Brugia malayi	follicle stimulating hormone receptor	0.011	0.0154	0.0154
Schistosoma mansoni	biogenic amine receptor	0.011	0.0154	0.0154
Echinococcus granulosus	neuropeptide receptor	0.011	0.0154	0.0154
Schistosoma mansoni	histamine h1 receptor	0.011	0.0154	0.0154
Echinococcus multilocularis		0.2019	0.7725	1
Brugia malayi	hypothetical protein	0.011	0.0154	0.0154
Echinococcus granulosus	neuropeptide Y receptor	0.011	0.0154	0.0154
Brugia malayi	RE15519p	0.011	0.0154	0.0154
Plasmodium vivax	subtilisin-like serine protease, putative	0.0127	0.0222	0.571
Mycobacterium leprae	Possible secreted protease	0.0127	0.0222	0.4914
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.011	0.0154	0.0199
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	proprotein convertase subtilisin:kexin type 5	0.1475	0.5568	0.7208
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Onchocerca volvulus		0.011	0.0154	0.1076
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	expressed protein	0.0368	0.1177	0.1524
Loa Loa (eye worm)	hypothetical protein	0.0378	0.1218	0.1218
Trichomonas vaginalis	cyclins, putative	0.0076	0.0021	0.0013
Toxoplasma gondii	subtilisin SUB1	0.0127	0.0222	0.4914
Echinococcus granulosus	cyclin B	0.0132	0.0243	0.0243
Schistosoma mansoni	furin-1 (S08 family)	0.1245	0.4654	0.4654
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0137	0.026	0.026
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Trichomonas vaginalis	leucine-rich repeat protein, BspA family	0.0574	0.1994	0.3565
Loa Loa (eye worm)	hypothetical protein	0.014	0.0273	0.0273
Echinococcus multilocularis	neuropeptide Y receptor	0.011	0.0154	0.0199
Echinococcus granulosus	proprotein convertase subtilisin:kexin type 5	0.1475	0.5568	0.5568
Loa Loa (eye worm)	cyclin domain-containing protein	0.0076	0.0021	0.0021
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.011	0.0154	0.0154
Brugia malayi	Cyclin, N-terminal domain containing protein	0.0132	0.0243	0.0243
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.014	0.0273	0.0273
Trichomonas vaginalis	cyclin B, putative	0.0132	0.0243	0.0412
Echinococcus multilocularis	cyclin B	0.0132	0.0243	0.0314
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.011	0.0154	0.0199
Echinococcus multilocularis	cyclins	0.0076	0.0021	0.0027
Schistosoma mansoni	biogenic amine (5HT) receptor	0.011	0.0154	0.0154
Onchocerca volvulus		0.011	0.0154	0.1076
Echinococcus multilocularis	fmrfamide receptor	0.011	0.0154	0.0199
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Schistosoma mansoni	Lysine-specific histone demethylase 1	0.0348	0.1101	0.1101
Schistosoma mansoni	Nep2 peptidase (M13 family)	0.0093	0.0089	0.0089
Trichomonas vaginalis	cyclin D, putative	0.0076	0.0021	0.0013
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.011	0.0154	0.0154
Schistosoma mansoni	growth hormone secretagogue receptor	0.011	0.0154	0.0154
Onchocerca volvulus	CoRest homolog	0.0167	0.0382	0.2989
Brugia malayi	putative neuropeptide receptor	0.011	0.0154	0.0154
Echinococcus granulosus	allatostatin A receptor	0.011	0.0154	0.0154
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.0175	0.0414	0.0414
Echinococcus multilocularis	serotonin receptor	0.011	0.0154	0.0199
Loa Loa (eye worm)	neuropeptide F receptor	0.011	0.0154	0.0154
Echinococcus granulosus	rhodopsin orphan GPCR	0.011	0.0154	0.0154
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.011	0.0154	0.0154
Toxoplasma gondii	subtilisin SUB5	0.0127	0.0222	0.4914
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Onchocerca volvulus		0.011	0.0154	0.1076
Echinococcus granulosus	7tm_1 domain containing protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Brugia malayi	hypothetical protein	0.011	0.0154	0.0154
Trichomonas vaginalis	conserved hypothetical protein	0.0574	0.1994	0.3565
Schistosoma mansoni	adenoreceptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0391	0.1268	0.1268
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0348	0.1101	0.1101
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.011	0.0154	0.0199
Echinococcus multilocularis	g-protein coupled receptor	0.011	0.0154	0.0199
Echinococcus granulosus	serotonin receptor	0.011	0.0154	0.0154
Echinococcus multilocularis	rhodopsin orphan GPCR	0.011	0.0154	0.0199
Echinococcus granulosus	neuropeptide receptor A26	0.011	0.0154	0.0154
Echinococcus granulosus	furin	0.2593	1	1
Plasmodium falciparum	subtilisin-like protease 2	0.0127	0.0222	0.571
Trichomonas vaginalis	proprotein convertase subtilisin/kexin type, putative	0.0622	0.2186	0.391
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.011	0.0154	0.0199
Echinococcus granulosus	cyclins	0.0076	0.0021	0.0021
Trichomonas vaginalis	cyclin B, putative	0.0132	0.0243	0.0412
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0175	0.0414	0.072
Mycobacterium ulcerans	membrane-anchored mycosin MycP3	0.0127	0.0222	0.4914
Echinococcus granulosus	cyclins	0.0076	0.0021	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0137	0.026	0.026
Onchocerca volvulus		0.0172	0.0403	0.3163
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Brugia malayi	proprotein convertase 2	0.1867	0.712	0.712
Giardia lamblia	Furin precursor putative serine protease	0.0622	0.2186	0.7816
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.011	0.0154	0.0199
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.011	0.0154	0.0154
Trichomonas vaginalis	conserved hypothetical protein	0.0574	0.1994	0.3565
Echinococcus multilocularis	dro:myosuppressin receptor	0.011	0.0154	0.0199
Echinococcus multilocularis	aminopeptidase N	0.0233	0.0644	0.0834
Echinococcus granulosus	cyclin b3	0.0076	0.0021	0.0021
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Plasmodium falciparum	cyclin	0.0076	0.0021	0.0537
Schistosoma mansoni	neuropeptide receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.0167	0.0382	0.0382
Trypanosoma cruzi	subtilisin-like serine peptidase, putative	0.0127	0.0222	0.9143
Echinococcus granulosus	tachykinin peptides receptor 99D	0.011	0.0154	0.0154
Schistosoma mansoni	neuropeptide receptor	0.011	0.0154	0.0154
Echinococcus granulosus	tm gpcr rhodopsin	0.011	0.0154	0.0154
Schistosoma mansoni	neuropeptide f receptor 76f	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.0348	0.1101	0.1101
Schistosoma mansoni	biogenic amine receptor	0.011	0.0154	0.0154
Schistosoma mansoni	hypothetical protein	0.011	0.0154	0.0154
Echinococcus granulosus	biogenic amine 5HT receptor	0.011	0.0154	0.0154
Echinococcus granulosus	rhodopsin orphan GPCR	0.011	0.0154	0.0154
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.011	0.0154	0.0154
Schistosoma mansoni	family A2 unassigned peptidase (A02 family)	0.0454	0.152	0.152
Echinococcus granulosus	rhodopsin orphan GPCR	0.011	0.0154	0.0154
Loa Loa (eye worm)	endoprotease bli-4	0.2593	1	1
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.0092	0.0085	0.0085
Loa Loa (eye worm)	peptidase family M1 containing protein	0.0189	0.0468	0.0468
Echinococcus granulosus	biogenic amine 5HT receptor	0.011	0.0154	0.0154
Schistosoma mansoni	cyclin B	0.0132	0.0243	0.0243
Echinococcus granulosus	rhodopsin orphan GPCR	0.011	0.0154	0.0154
Schistosoma mansoni	tripeptidyl-peptidase II (S08 family)	0.0127	0.0222	0.0222
Toxoplasma gondii	subtilisin SUB9	0.0127	0.0222	0.4914
Onchocerca volvulus		0.0132	0.0243	0.1822
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.011	0.0154	0.0154
Trichomonas vaginalis	conserved hypothetical protein	0.0574	0.1994	0.3565
Echinococcus granulosus	neuropeptide FF receptor 2	0.011	0.0154	0.0154
Loa Loa (eye worm)	TYRA-2 protein	0.011	0.0154	0.0154
Brugia malayi	hypothetical protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0137	0.026	0.026
Onchocerca volvulus		0.011	0.0154	0.1076
Loa Loa (eye worm)	hypothetical protein	0.014	0.0273	0.0273
Brugia malayi	G protein-coupled receptor	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0749	0.2689	0.4815
Trichomonas vaginalis	cyclin B, putative	0.0132	0.0243	0.0412
Echinococcus multilocularis	cyclins	0.0076	0.0021	0.0027
Chlamydia trachomatis	protoporphyrinogen oxidase	0.0071	0	0.5
Loa Loa (eye worm)	subtilase	0.0127	0.0222	0.0222
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Schistosoma mansoni	cyclin B3	0.0076	0.0021	0.0021
Trichomonas vaginalis	cyclins, putative	0.0132	0.0243	0.0412
Schistosoma mansoni	biogenic amine (5HT) receptor	0.011	0.0154	0.0154
Brugia malayi	hypothetical protein	0.011	0.0154	0.0154
Mycobacterium tuberculosis	Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4)	0.0127	0.0222	0.4914
Schistosoma mansoni	biogenic amine receptor	0.011	0.0154	0.0154
Trichomonas vaginalis	cyclin B, putative	0.0132	0.0243	0.0412
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	cyclins	0.0076	0.0021	0.0027
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.011	0.0154	0.0199
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.011	0.0154	0.0199
Toxoplasma gondii	subtilisin SUB7	0.0127	0.0222	0.4914
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	cyclins	0.0076	0.0021	0.0027
Loa Loa (eye worm)	hypothetical protein	0.014	0.0273	0.0273
Brugia malayi	G-protein coupled receptor	0.011	0.0154	0.0154
Plasmodium vivax	subtilisin-like protease 1	0.0127	0.0222	0.571
Brugia malayi	celfurPC protein	0.2019	0.7725	0.7725
Trichomonas vaginalis	conserved hypothetical protein	0.0574	0.1994	0.3565
Loa Loa (eye worm)	hypothetical protein	0.0185	0.0452	0.0452
Brugia malayi	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	g protein coupled receptor	0.011	0.0154	0.0199
Loa Loa (eye worm)	neuropeptide F receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Onchocerca volvulus		0.011	0.0154	0.1076
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.011	0.0154	0.1076
Echinococcus granulosus	Furin 1	0.0749	0.2689	0.2689
Trichomonas vaginalis	cyclin A, putative	0.0132	0.0243	0.0412
Echinococcus multilocularis	fmrfamide receptor	0.011	0.0154	0.0199
Echinococcus multilocularis	G2:mitotic specific cyclin B3	0.0076	0.0021	0.0027
Echinococcus multilocularis	cyclins	0.0076	0.0021	0.0027
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Brugia malayi	hypothetical protein	0.011	0.0154	0.0154
Schistosoma mansoni	hypothetical protein	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Schistosoma mansoni	neuropeptide receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.0137	0.026	0.026
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Echinococcus granulosus	neuropeptide Y receptor	0.011	0.0154	0.0154
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0082	0.0082
Brugia malayi	G protein-coupled receptor F59B2.13	0.011	0.0154	0.0154
Schistosoma mansoni	cyclins	0.0076	0.0021	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0209	0.0549	0.0549
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Schistosoma mansoni	amine GPCR	0.011	0.0154	0.0154
Trichomonas vaginalis	conserved hypothetical protein	0.0574	0.1994	0.3565
Onchocerca volvulus		0.0196	0.0496	0.3946
Loa Loa (eye worm)	G-protein coupled receptor	0.011	0.0154	0.0154
Brugia malayi	GnHR receptor homolog	0.011	0.0154	0.0154
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.011	0.0154	0.0154
Mycobacterium leprae	PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3)	0.0127	0.0222	0.4914
Onchocerca volvulus	Neuropeptide F receptor homolog	0.011	0.0154	0.1076
Mycobacterium ulcerans	proline rich membrane-anchored mycosin MycP5	0.0127	0.0222	0.4914
Toxoplasma gondii	cathepsin CPC2	0.0169	0.0389	0.8606
Echinococcus multilocularis	neuropeptide receptor	0.011	0.0154	0.0199
Echinococcus multilocularis	lysine specific histone demethylase 1A	0.0348	0.1101	0.1425
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Schistosoma mansoni	amine GPCR	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0749	0.2689	0.4815
Schistosoma mansoni	neprilysin-2 (M13 family)	0.0093	0.0089	0.0089
Mycobacterium tuberculosis	Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3)	0.0127	0.0222	0.4914
Brugia malayi	putative neuropeptide receptor NPR1	0.011	0.0154	0.0154
Leishmania major	subtilisin-like serine peptidase	0.0127	0.0222	0.9143
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Mycobacterium tuberculosis	Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase)	0.0165	0.0374	0.8277
Trichomonas vaginalis	conserved hypothetical protein	0.0127	0.0222	0.0374
Schistosoma mansoni	hypothetical protein	0.011	0.0154	0.0154
Schistosoma mansoni	site-1 peptidase (S08 family)	0.0127	0.0222	0.0222
Brugia malayi	Serotonin receptor	0.011	0.0154	0.0154
Echinococcus granulosus	cyclins	0.0076	0.0021	0.0021
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.0169	0.0389	1
Brugia malayi	Hypothetical zinc metalloproteinase T16A9.4	0.0185	0.0452	0.0452
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.1475	0.5568	1
Echinococcus multilocularis	neuroendocrine convertase 2	0.1867	0.712	0.9217
Echinococcus multilocularis	endothelin converting enzyme 1	0.0185	0.0452	0.0585
Echinococcus granulosus	fmrfamide receptor	0.011	0.0154	0.0154
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Leishmania major	cyclin	0.0132	0.0243	1
Trypanosoma cruzi	subtilisin-like serine peptidase, putative	0.0127	0.0222	0.9143
Trypanosoma cruzi	serine peptidase, clan SB, family S8-like protein	0.0127	0.0222	0.9143
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.011	0.0154	0.0154
Onchocerca volvulus		0.011	0.0154	0.1076
Trichomonas vaginalis	conserved hypothetical protein	0.0574	0.1994	0.3565
Mycobacterium leprae	PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5)	0.0127	0.0222	0.4914
Brugia malayi	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	rhodopsin orphan GPCR	0.011	0.0154	0.0199
Toxoplasma gondii	subtilisin SUB8	0.0127	0.0222	0.4914
Echinococcus granulosus	cyclins	0.0076	0.0021	0.0021
Trichomonas vaginalis	conserved hypothetical protein	0.0574	0.1994	0.3565
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.014	0.0273	0.0273
Giardia lamblia	High cysteine membrane protein Group 2	0.0775	0.2791	1
Echinococcus multilocularis	cyclins	0.0076	0.0021	0.0027
Schistosoma mansoni	hypothetical protein	0.011	0.0154	0.0154
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.011	0.0154	0.0154
Echinococcus granulosus	neuropeptides capa receptor	0.011	0.0154	0.0154
Trichomonas vaginalis	cyclins, putative	0.0132	0.0243	0.0412
Echinococcus granulosus	tm gpcr rhodopsin	0.011	0.0154	0.0154
Echinococcus multilocularis	rhodopsin orphan GPCR	0.011	0.0154	0.0199
Mycobacterium tuberculosis	Probable zinc metalloprotease Zmp1	0.0185	0.0452	1
Echinococcus granulosus	G protein coupled receptor 139	0.011	0.0154	0.0154
Brugia malayi	Trypsin family protein	0.0196	0.0496	0.0496
Echinococcus multilocularis	orexin receptor type 2	0.011	0.0154	0.0199
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0093	0.0089	0.0089
Onchocerca volvulus		0.011	0.0154	0.1076
Entamoeba histolytica	cyclin, putative	0.0132	0.0243	1
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.011	0.0154	0.0154
Brugia malayi	Furin-like cysteine rich region family protein	0.0391	0.1268	0.1268
Echinococcus multilocularis	g protein coupled receptor	0.011	0.0154	0.0199
Trichomonas vaginalis	conserved hypothetical protein	0.0574	0.1994	0.3565
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.1639	0.6218	0.8049
Trypanosoma cruzi	cyclin, putative	0.0132	0.0243	1
Schistosoma mansoni	subfamily S8B non-peptidase homologue (S08 family)	0.0749	0.2689	0.2689
Toxoplasma gondii	peptidase family M13 protein	0.0185	0.0452	1
Loa Loa (eye worm)	hypothetical protein	0.0162	0.0363	0.0363
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0196	0.0496	0.0496
Schistosoma mansoni	hypothetical protein	0.0574	0.1994	0.1994
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Trypanosoma cruzi	cyclin 6, putative	0.0132	0.0243	1
Onchocerca volvulus		0.011	0.0154	0.1076
Trypanosoma cruzi	cyclin, putative	0.0132	0.0243	1
Echinococcus granulosus	g protein coupled receptor	0.011	0.0154	0.0154
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.011	0.0154	0.0199
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.011	0.0154	0.0154
Toxoplasma gondii	subtilisin SUB4	0.0127	0.0222	0.4914
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.011	0.0154	0.0154
Mycobacterium ulcerans	zinc metalloprotease	0.0185	0.0452	1
Trichomonas vaginalis	conserved hypothetical protein	0.0574	0.1994	0.3565
Onchocerca volvulus		0.011	0.0154	0.1076
Onchocerca volvulus		0.0092	0.0082	0.0475
Loa Loa (eye worm)	hypothetical protein	0.0185	0.0452	0.0452
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.011	0.0154	0.0154
Onchocerca volvulus		0.011	0.0154	0.1076
Onchocerca volvulus		0.011	0.0154	0.1076
Onchocerca volvulus		0.0127	0.0222	0.1648
Mycobacterium leprae	probable zinc metalloprotease	0.0185	0.0452	1
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Brugia malayi	AKH receptor	0.011	0.0154	0.0154
Echinococcus multilocularis	rhodopsin orphan GPCR	0.011	0.0154	0.0199
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.011	0.0154	0.0154
Trypanosoma cruzi	CYC2-like cyclin, putative	0.0132	0.0243	1
Echinococcus granulosus	epidermal growth factor receptor	0.0391	0.1268	0.1268
Onchocerca volvulus		0.011	0.0154	0.1076
Trichomonas vaginalis	conserved hypothetical protein	0.0127	0.0222	0.0374
Trichomonas vaginalis	cyclin B3, putative	0.0076	0.0021	0.0013
Brugia malayi	Hypothetical subtilase-type proteinase F21H12.6 in chromosome II	0.0127	0.0222	0.0222
Trypanosoma cruzi	subtilisin peptidase	0.0127	0.0222	0.9143
Onchocerca volvulus		0.011	0.0154	0.1076
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Brugia malayi	sulfakinin receptor protein	0.011	0.0154	0.0154
Schistosoma mansoni	amine GPCR	0.011	0.0154	0.0154
Onchocerca volvulus		0.011	0.0154	0.1076
Leishmania major	CYC2-like cyclin, putative,cyclin 6, putative	0.0132	0.0243	1
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	allatostatin A receptor	0.011	0.0154	0.0199
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.011	0.0154	0.0199
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Trichomonas vaginalis	cyclins, putative	0.0132	0.0243	0.0412
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Toxoplasma gondii	subtilisin SUB10	0.0127	0.0222	0.4914
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.014	0.0273	0.0273
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.011	0.0154	0.0154
Mycobacterium tuberculosis	Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5)	0.0127	0.0222	0.4914
Loa Loa (eye worm)	hypothetical protein	0.0127	0.0222	0.0222
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.011	0.0154	0.0154
Echinococcus granulosus	endothelin converting enzyme 1	0.0185	0.0452	0.0452
Brugia malayi	Serotonin receptor	0.011	0.0154	0.0154
Brugia malayi	Dopamine receptor protein 1	0.011	0.0154	0.0154
Brugia malayi	neuropeptide F receptor	0.011	0.0154	0.0154
Schistosoma mansoni	family M13 non-peptidase homologue (M13 family)	0.0093	0.0089	0.0089
Echinococcus granulosus	g-protein coupled receptor	0.011	0.0154	0.0154
Schistosoma mansoni	opsin-like receptor	0.011	0.0154	0.0154
Schistosoma mansoni	amine GPCR	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Trichomonas vaginalis	neuroendocrine convertase 2 precursor, putative	0.0622	0.2186	0.391
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0093	0.0089	0.0089
Echinococcus granulosus	neuropeptides capa receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Trichomonas vaginalis	conserved hypothetical protein	0.0127	0.0222	0.0374
Loa Loa (eye worm)	hypothetical protein	0.01	0.0117	0.0117
Plasmodium vivax	subtilisin-like protease 2, putative	0.0127	0.0222	0.571
Schistosoma mansoni	intracisternal A-particle retropepsin (A02 family)	0.2499	0.9626	0.9626
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0185	0.0452	0.0452
Brugia malayi	ORL1-like opioid receptor	0.011	0.0154	0.0154
Brugia malayi	hypothetical protein	0.011	0.0154	0.0154
Trichomonas vaginalis	conserved hypothetical protein	0.0127	0.0222	0.0374
Echinococcus multilocularis	rhodopsin orphan GPCR	0.011	0.0154	0.0199
Trypanosoma brucei	mitotic cyclin 6	0.0132	0.0243	1
Brugia malayi	neuropeptide F receptor	0.011	0.0154	0.0154
Brugia malayi	hypothetical protein	0.011	0.0154	0.0154
Echinococcus granulosus	somatostatin receptor	0.011	0.0154	0.0154
Echinococcus multilocularis	neuropeptide receptor	0.011	0.0154	0.0199
Plasmodium falciparum	subtilisin-like protease 1	0.0127	0.0222	0.571
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Echinococcus granulosus	tm gpcr rhodopsin	0.1639	0.6218	0.6218
Onchocerca volvulus		0.011	0.0154	0.1076
Echinococcus multilocularis	cyclin b3	0.0076	0.0021	0.0027
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Loa Loa (eye worm)	melatonin receptor type 1A	0.011	0.0154	0.0154
Echinococcus granulosus	7TM GPCR rhodopsin	0.011	0.0154	0.0154
Echinococcus multilocularis	serotonin receptor	0.011	0.0154	0.0199
Echinococcus granulosus	neuropeptide s receptor	0.011	0.0154	0.0154
Echinococcus granulosus	g protein coupled receptor	0.011	0.0154	0.0154
Echinococcus granulosus	rhodopsin orphan GPCR	0.011	0.0154	0.0154
Brugia malayi	SWIRM domain containing protein	0.0378	0.1218	0.1218
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Loa Loa (eye worm)	hypothetical protein	0.0348	0.1101	0.1101
Mycobacterium ulcerans	epoxide hydrolase EphA	0.0165	0.0374	0.8277
Toxoplasma gondii	subtilisin SUB11	0.0127	0.0222	0.4914
Loa Loa (eye worm)	hypothetical protein	0.0165	0.0372	0.0372
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.011	0.0154	0.0199
Echinococcus granulosus	orexin receptor type 2	0.011	0.0154	0.0154
Giardia lamblia	G2/mitotic-specific cyclin B	0.0132	0.0243	0.0801
Schistosoma mansoni	opsin-like receptor	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Echinococcus multilocularis	G protein coupled receptor 139	0.011	0.0154	0.0199
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Echinococcus granulosus	sex peptide receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	neuropeptide FF receptor 2	0.011	0.0154	0.0199
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Schistosoma mansoni	opsin-like receptor	0.011	0.0154	0.0154
Echinococcus granulosus	dro:myosuppressin receptor	0.011	0.0154	0.0154
Echinococcus multilocularis	Furin 1	0.0749	0.2689	0.348
Echinococcus granulosus	rhodopsin orphan GPCR	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0243	0.0243
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	rhodopsin orphan GPCR	0.011	0.0154	0.0199
Trichomonas vaginalis	cyclins, putative	0.0132	0.0243	0.0412
Echinococcus granulosus	rhodopsin orphan GPCR	0.011	0.0154	0.0154
Echinococcus granulosus	neuroendocrine convertase 2	0.1867	0.712	0.712
Onchocerca volvulus		0.011	0.0154	0.1076
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.011	0.0154	0.0154
Brugia malayi	neuroendocrine convertase 1 precursor	0.2173	0.8333	0.8333
Echinococcus granulosus	alpha 1A adrenergic receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	G-protein coupled receptor	0.011	0.0154	0.0154
Schistosoma mansoni	neuropeptide receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.2593	1	1
Brugia malayi	hypothetical protein	0.011	0.0154	0.0154
Echinococcus granulosus	cyclins	0.0076	0.0021	0.0021
Trichomonas vaginalis	hypothetical protein	0.0574	0.1994	0.3565
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Trichomonas vaginalis	conserved hypothetical protein	0.0076	0.0021	0.0013
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.011	0.0154	0.0154
Echinococcus granulosus	expressed protein	0.0368	0.1177	0.1177
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.011	0.0154	0.0154
Echinococcus granulosus	g protein coupled receptor	0.011	0.0154	0.0154
Brugia malayi	Cyclin, N-terminal domain containing protein	0.0132	0.0243	0.0243
Echinococcus multilocularis	G-protein coupled receptor, putative	0.011	0.0154	0.0199
Schistosoma mansoni	neuropeptide F-like receptor	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Echinococcus multilocularis	rhodopsin orphan GPCR	0.011	0.0154	0.0199
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.011	0.0154	0.0154
Echinococcus granulosus	hypothetical protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.0354	0.1124	0.1124
Brugia malayi	Cyclin, N-terminal domain containing protein	0.0076	0.0021	0.0021
Loa Loa (eye worm)	hypothetical protein	0.1166	0.4343	0.4343
Brugia malayi	Myb-like DNA-binding domain containing protein	0.0162	0.0363	0.0363
Onchocerca volvulus		0.011	0.0154	0.1076
Brugia malayi	Peptidase family M1 containing protein	0.0233	0.0644	0.0644
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Plasmodium falciparum	subtilisin-like protease 3	0.0127	0.0222	0.571
Echinococcus multilocularis	neuropeptides capa receptor	0.011	0.0154	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0137	0.026	0.026
Loa Loa (eye worm)	proprotein convertase 2	0.0749	0.2689	0.2689
Loa Loa (eye worm)	hypothetical protein	0.0137	0.026	0.026
Brugia malayi	Subtilase family protein	0.0127	0.0222	0.0222
Schistosoma mansoni	myosin xvIII	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0749	0.2689	0.4815
Mycobacterium ulcerans	membrane-anchored serine protease (mycosin), MycP4	0.0127	0.0222	0.4914
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Brugia malayi	Membrane-bound transcription factor site-1 protease precursor	0.0127	0.0222	0.0222
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Brugia malayi	G-protein coupled receptor	0.011	0.0154	0.0154
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.011	0.0154	0.0154
Brugia malayi	larval opioid receptor	0.011	0.0154	0.0154
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.011	0.0154	0.0154
Echinococcus multilocularis	somatostatin receptor	0.011	0.0154	0.0199
Echinococcus multilocularis	neuropeptides capa receptor	0.011	0.0154	0.0199
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Brugia malayi	Melatonin receptor type 1A	0.011	0.0154	0.0154
Trichomonas vaginalis	conserved hypothetical protein	0.0574	0.1994	0.3565
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.011	0.0154	0.0199
Echinococcus multilocularis	g protein coupled receptor	0.011	0.0154	0.0199
Brugia malayi	Peptidase family M13 containing protein	0.0185	0.0452	0.0452
Mycobacterium tuberculosis	Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like)	0.0127	0.0222	0.4914
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	cyclins	0.0076	0.0021	0.0027
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.1475	0.5568	1
Echinococcus multilocularis	cyclin B3 1	0.0076	0.0021	0.0027
Echinococcus granulosus	peptidase s8 s53 subtilisin kexin sedolisin	0.0127	0.0222	0.0222
Loa Loa (eye worm)	hypothetical protein	0.0196	0.0496	0.0496
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0749	0.2689	0.4815
Echinococcus multilocularis	neuropeptide Y receptor	0.011	0.0154	0.0199
Brugia malayi	Dopamine receptor	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0749	0.2689	0.4815
Echinococcus multilocularis	rhodopsin orphan GPCR	0.011	0.0154	0.0199
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.011	0.0154	0.0199
Onchocerca volvulus		0.0233	0.0644	0.5191
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0243	0.0243
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Echinococcus granulosus	cyclin B3 1	0.0076	0.0021	0.0021
Echinococcus granulosus	neuropeptide receptor	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Trichomonas vaginalis	conserved hypothetical protein	0.0574	0.1994	0.3565
Schistosoma mansoni	alpha-1 adrenergic receptor	0.011	0.0154	0.0154
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.011	0.0154	0.0199
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0749	0.2689	0.4815
Trichomonas vaginalis	conserved hypothetical protein	0.0127	0.0222	0.0374
Schistosoma mansoni	tyrosine kinase	0.0391	0.1268	0.1268
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Echinococcus granulosus	membrane bound transcription factor site 1	0.0127	0.0222	0.0222
Onchocerca volvulus		0.0378	0.1218	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.011	0.0154	0.0154
Schistosoma mansoni	neuropeptide F-like receptor	0.011	0.0154	0.0154
Echinococcus granulosus	peptide allatostatin:somatostatin	0.011	0.0154	0.0154
Brugia malayi	amine oxidase, flavin-containing family protein	0.01	0.0117	0.0117
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.011	0.0154	0.0154
Echinococcus multilocularis	neuropeptide s receptor	0.011	0.0154	0.0199
Echinococcus granulosus	aminopeptidase N	0.0233	0.0644	0.0644
Echinococcus granulosus	G2:mitotic specific cyclin B3	0.0076	0.0021	0.0021
Toxoplasma gondii	subtilisin SUB12	0.0127	0.0222	0.4914
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	Peptidase S8 S53, subtilisin kexin sedolisin	0.0127	0.0222	0.0287
Brugia malayi	Dopamine receptor protein 2	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154
Echinococcus multilocularis	membrane bound transcription factor site 1	0.0127	0.0222	0.0287
Loa Loa (eye worm)	hypothetical protein	0.0185	0.0452	0.0452
Schistosoma mansoni	amine GPCR	0.011	0.0154	0.0154
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0127	0.0222	0.0374
Toxoplasma gondii	subtilisin SUB6	0.0127	0.0222	0.4914
Loa Loa (eye worm)	hypothetical protein	0.011	0.0154	0.0154

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1796966

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1016790