Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0309 | 0.0364 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.001 | 0.0039 | 0.0544 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0041 | 0.0074 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.001 | 0.0039 | 0.1769 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.001 | 0.0039 | 0.053 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.0724 | 1 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0025 | 0.0196 | 0.3221 |
Entamoeba histolytica | hypothetical protein | 0.0028 | 0.0223 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0071 | 0.0129 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.002 | 0.014 | 0.014 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.0724 | 1 |
Leishmania major | importin beta-1 subunit, putative | 0.0028 | 0.0223 | 0.3073 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.001 | 0.0039 | 0.1769 |
Brugia malayi | cathepsin L-like precursor | 0.0013 | 0.0071 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Echinococcus multilocularis | cysteine protease | 0.002 | 0.014 | 0.014 |
Echinococcus granulosus | cathepsin l1 | 0.0013 | 0.0071 | 0.0084 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Echinococcus granulosus | importin subunit beta 1 | 0.0034 | 0.029 | 0.0342 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0024 | 0.0177 | 0.0321 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0013 | 0.0588 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0021 | 0.0025 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0045 | 0.0396 | 0.0716 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0396 | 0.0716 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0045 | 0.0396 | 0.0716 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.014 | 0.0253 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0822 | 0.85 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0021 | 0.0151 | 0.0151 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0289 | 0.034 |
Brugia malayi | conserved hypotetical protein | 0.0021 | 0.0151 | 0.0273 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.0724 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0045 | 0.0396 | 0.0466 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0071 | 0.321 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0045 | 0.0396 | 0.0466 |
Brugia malayi | Papain family cysteine protease containing protein | 0.001 | 0.0039 | 0.0071 |
Leishmania major | cysteine peptidase A (CPA) | 0.002 | 0.014 | 0.1935 |
Leishmania major | cathepsin L-like protease | 0.0076 | 0.0724 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0045 | 0.0396 | 0.0396 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0002 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0177 | 0.0321 |
Mycobacterium tuberculosis | Possible toxin MazF7 | 0.0159 | 0.1589 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.014 | 0.0253 |
Entamoeba histolytica | cysteine protease, putative | 0.002 | 0.014 | 0.6298 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Mycobacterium tuberculosis | Possible toxin MazF1 | 0.0159 | 0.1589 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Schistosoma mansoni | thyroid hormone receptor | 0.0045 | 0.0396 | 0.0466 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0025 | 0.0196 | 0.2692 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0045 | 0.0396 | 0.0716 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0045 | 0.0396 | 0.0716 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0045 | 0.0396 | 0.0716 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.002 | 0.014 | 0.4829 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0045 | 0.0396 | 0.0716 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0013 | 0.0588 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0045 | 0.0396 | 0.0595 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.0724 | 1 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0196 | 0.6744 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0071 | 0.0129 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0021 | 0.0151 | 0.0146 |
Brugia malayi | ecdysone receptor | 0.0021 | 0.0151 | 0.0273 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Onchocerca volvulus | Cathepsin L homolog | 0.002 | 0.014 | 0.0126 |
Brugia malayi | nuclear receptor RXR | 0.0024 | 0.0177 | 0.0321 |
Onchocerca volvulus | 0.002 | 0.014 | 0.0126 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0045 | 0.0396 | 0.0716 |
Schistosoma mansoni | hypothetical protein | 0.0487 | 0.5011 | 0.5895 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0034 | 0.029 | 0.029 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.014 | 0.1935 |
Trypanosoma cruzi | cysteine protease, putative | 0.001 | 0.0039 | 0.053 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0045 | 0.0396 | 0.0396 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0024 | 0.0177 | 0.0209 |
Onchocerca volvulus | 0.002 | 0.014 | 0.0126 | |
Trichomonas vaginalis | importin beta-1, putative | 0.0028 | 0.0223 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0002 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.001 | 0.0039 | 0.0046 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0028 | 0.0223 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0021 | 0.0151 | 0.0178 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0069 | 0.0656 | 0.905 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.014 | 0.0253 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0025 | 0.0196 | 0.023 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.014 | 0.0165 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0045 | 0.0396 | 0.0466 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.014 | 0.0253 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0065 | 0.0608 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0045 | 0.0396 | 0.0716 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0045 | 0.0396 | 0.0716 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0076 | 0.0724 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0045 | 0.0396 | 0.0716 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Echinococcus multilocularis | cathepsin L | 0.001 | 0.0039 | 0.0039 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.0724 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0013 | 0.0071 | 0.0129 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0045 | 0.0396 | 0.0716 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0021 | 0.0151 | 0.0151 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.002 | 0.014 | 0.014 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0021 | 0.0151 | 0.0273 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0021 | 0.0151 | 0.0178 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.014 | 0.0253 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0367 | 0.3754 | 0.6788 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0045 | 0.0396 | 0.0466 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0024 | 0.0177 | 0.0177 |
Leishmania major | cathepsin L-like protease | 0.0076 | 0.0724 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0024 | 0.0177 | 0.0209 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0013 | 0.0071 | 0.321 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.0151 | 0.0273 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0021 | 0.0021 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0013 | 0.0071 | 0.0084 |
Plasmodium vivax | vivapain-3 | 0.001 | 0.0039 | 0.1357 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0045 | 0.0396 | 0.0466 |
Echinococcus granulosus | cpg binding protein | 0.0036 | 0.0309 | 0.0364 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.0724 | 1 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0021 | 0.0025 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.001 | 0.0039 | 0.1357 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0537 | 0.5531 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.001 | 0.0039 | 0.0071 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0021 | 0.0151 | 0.0178 |
Schistosoma mansoni | cathepsin s | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | snurportin 1 | 0.0367 | 0.3754 | 0.3754 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Brugia malayi | hypothetical protein | 0.018 | 0.1808 | 0.327 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0045 | 0.0396 | 0.0716 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0034 | 0.029 | 0.4008 |
Onchocerca volvulus | 0.018 | 0.1808 | 0.3182 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.002 | 0.014 | 0.0253 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0396 | 0.0716 |
Echinococcus granulosus | snurportin 1 | 0.0367 | 0.3754 | 0.4417 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0076 | 0.0724 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0045 | 0.0396 | 0.0466 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0822 | 0.85 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0.0013 | 0.0588 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.002 | 0.014 | 0.0253 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Mycobacterium tuberculosis | Conserved protein | 0.0159 | 0.1589 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.0724 | 1 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.014 | 0.1935 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0.0013 | 0.0588 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.001 | 0.0039 | 0.0046 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Plasmodium vivax | vivapain-2 | 0.002 | 0.014 | 0.4829 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0013 | 0.0588 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0076 | 0.0724 | 1 |
Mycobacterium tuberculosis | Possible toxin MazF4 | 0.0159 | 0.1589 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0024 | 0.0177 | 0.0321 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0028 | 0.0223 | 0.3063 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0021 | 0.0151 | 0.0178 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0045 | 0.0396 | 0.0466 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0045 | 0.0396 | 0.0716 |
Schistosoma mansoni | ran | 0.0025 | 0.0196 | 0.023 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0151 | 0.0178 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0045 | 0.0396 | 0.0466 |
Mycobacterium tuberculosis | Toxin MazF6 | 0.0159 | 0.1589 | 0.5 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.001 | 0.0039 | 0.053 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Plasmodium vivax | importin-beta 2, putative | 0.0034 | 0.029 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.002 | 0.014 | 0.0253 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0045 | 0.0396 | 0.0466 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0045 | 0.0396 | 0.0396 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0021 | 0.0151 | 0.0273 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Entamoeba histolytica | cysteine proteinase, putative | 0.001 | 0.0039 | 0.1769 |
Echinococcus granulosus | dnaJ subfamily B | 0.0487 | 0.5011 | 0.5895 |
Plasmodium vivax | vivapain-2 | 0.002 | 0.014 | 0.4829 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0487 | 0.5011 | 0.5011 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0045 | 0.0396 | 0.0716 |
Entamoeba histolytica | cysteine proteinase, putative | 0.002 | 0.014 | 0.6298 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0045 | 0.0396 | 0.0466 |
Schistosoma mansoni | hypothetical protein | 0.0367 | 0.3754 | 0.4417 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0025 | 0.0196 | 0.0196 |
Onchocerca volvulus | 0.002 | 0.014 | 0.0126 | |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0045 | 0.0396 | 0.0396 |
Brugia malayi | Cathepsin L-like precursor | 0.0007 | 0.0001 | 0.0002 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0045 | 0.0396 | 0.0466 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0013 | 0.0588 |
Echinococcus multilocularis | cysteine protease | 0.002 | 0.014 | 0.014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0013 | 0.0588 |
Entamoeba histolytica | cysteine proteinase, putative | 0.002 | 0.014 | 0.6298 |
Brugia malayi | nuclear hormone receptor | 0.0045 | 0.0396 | 0.0716 |
Mycobacterium tuberculosis | Toxin MazF2 | 0.0159 | 0.1589 | 0.5 |
Brugia malayi | nuclear receptor NHR-67 | 0.0021 | 0.0151 | 0.0273 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0013 | 0.0588 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0045 | 0.0396 | 0.0466 |
Schistosoma mansoni | thyroid hormone receptor | 0.0045 | 0.0396 | 0.0466 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.001 | 0.0039 | 0.053 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0021 | 0.0151 | 0.0273 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0034 | 0.029 | 0.4008 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0045 | 0.0396 | 0.0466 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0309 | 0.0364 |
Onchocerca volvulus | 0.0034 | 0.0289 | 0.0398 | |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0396 | 0.0716 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0013 | 0.0588 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0013 | 0.0588 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.1808 | 0.327 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.001 | 0.0039 | 0.0544 |
Onchocerca volvulus | 0.0021 | 0.0151 | 0.0146 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.002 | 0.014 | 0.0165 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0151 | 0.0178 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0025 | 0.0196 | 0.6744 |
Loa Loa (eye worm) | fibroinase | 0.002 | 0.014 | 0.0253 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.0724 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0177 | 0.0321 |
Schistosoma mansoni | nuclear hormone receptor | 0.0045 | 0.0396 | 0.0466 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0013 | 0.0588 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0021 | 0.0025 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0196 | 0.0354 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0013 | 0.0071 | 0.0129 |
Mycobacterium tuberculosis | Possible toxin MazF5 | 0.0159 | 0.1589 | 0.5 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0013 | 0.0588 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0021 | 0.0151 | 0.0178 |
Onchocerca volvulus | 0.002 | 0.014 | 0.0126 | |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Entamoeba histolytica | cysteine proteinase, putative | 0.001 | 0.0039 | 0.1769 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.001 | 0.0039 | 0.1769 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0071 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0002 |
Brugia malayi | nuclear receptor NHR-88 | 0.0045 | 0.0396 | 0.0716 |
Onchocerca volvulus | 0.0045 | 0.0396 | 0.0595 | |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0396 | 0.0716 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.014 | 0.1935 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.029 | 0.0525 |
Mycobacterium tuberculosis | Toxin MazF3 | 0.0159 | 0.1589 | 0.5 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0021 | 0.0151 | 0.0178 |
Entamoeba histolytica | cysteine proteinase, putative | 0.001 | 0.0039 | 0.1769 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Leishmania major | cathepsin L-like protease | 0.0076 | 0.0724 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0045 | 0.0396 | 0.0396 |
Schistosoma mansoni | coup transcription factor | 0.0045 | 0.0396 | 0.0466 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0021 | 0.0151 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0396 | 0.0716 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0007 | 0.0001 | 0.0002 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0073 | 0.0689 | 0.081 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.014 | 0.0253 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0034 | 0.029 | 0.4776 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0025 | 0.0196 | 0.2703 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.0724 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0021 | 0.0151 | 0.0146 |
Schistosoma mansoni | importin beta-1 | 0.0034 | 0.029 | 0.0342 |
Echinococcus granulosus | FTZ F1 alpha | 0.0045 | 0.0396 | 0.0466 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0822 | 0.85 | 0.85 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0196 | 0.5 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0021 | 0.0151 | 0.0273 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0045 | 0.0396 | 0.0396 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0007 | 0.0001 | 0.0002 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0045 | 0.0396 | 0.0396 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Schistosoma mansoni | nuclear receptor | 0.0021 | 0.0151 | 0.0178 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0045 | 0.0396 | 0.0716 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0021 | 0.0151 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0177 | 0.0321 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.002 | 0.014 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.001 | 0.0039 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0177 | 0.0321 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0045 | 0.0396 | 0.0396 |
Brugia malayi | tailless protein | 0.0021 | 0.0151 | 0.0273 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0043 | 0.005 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.0151 | 0.0273 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0045 | 0.0396 | 0.0716 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0045 | 0.0396 | 0.0716 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0076 | 0.0724 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.014 | 0.0253 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0013 | 0.0588 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0396 | 0.0716 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.014 | 0.0165 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0021 | 0.0151 | 0.0273 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0045 | 0.0396 | 0.0716 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0071 | 0.0129 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0045 | 0.0396 | 0.0466 |
Onchocerca volvulus | 0.0021 | 0.0151 | 0.0146 | |
Mycobacterium tuberculosis | Toxin MazF9 | 0.0159 | 0.1589 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0396 | 0.0716 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0151 | 0.0151 |
Brugia malayi | steroid hormone receptor | 0.0045 | 0.0396 | 0.0716 |
Brugia malayi | RNA, U transporter 1 | 0.0098 | 0.095 | 0.1718 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0196 | 0.0354 |
Echinococcus granulosus | cathepsin l1 | 0.002 | 0.014 | 0.0165 |
Entamoeba histolytica | cysteine proteinase 2 | 0.001 | 0.0039 | 0.1769 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0177 | 0.0321 |
Entamoeba histolytica | Ran family GTPase | 0.0025 | 0.0196 | 0.8795 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0151 | 0.0178 |
Brugia malayi | CXXC zinc finger family protein | 0.0034 | 0.0289 | 0.0522 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0045 | 0.0396 | 0.0595 |
Trichomonas vaginalis | ran, putative | 0.0025 | 0.0196 | 0.8795 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0024 | 0.0177 | 0.0321 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0021 | 0.0151 | 0.0151 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0013 | 0.0588 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.006 | 0.0555 | 0.7656 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.014 | 0.1935 |
Loa Loa (eye worm) | ctsf protein | 0.002 | 0.014 | 0.0253 |
Onchocerca volvulus | Cathepsin F homolog | 0.002 | 0.014 | 0.0126 |
Plasmodium vivax | unspecified product | 0.0007 | 0.0001 | 0.0035 |
Loa Loa (eye worm) | histone methyltransferase | 0.0011 | 0.0043 | 0.0077 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0045 | 0.0396 | 0.0466 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0024 | 0.0177 | 0.0209 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.002 | 0.014 | 0.4829 |
Onchocerca volvulus | Cathepsin L homolog | 0.002 | 0.014 | 0.0126 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.0724 | 1 |
Onchocerca volvulus | 0.002 | 0.014 | 0.0126 | |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0045 | 0.0396 | 0.0466 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0021 | 0.0021 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0013 | 0.0588 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0034 | 0.0289 | 0.0522 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0045 | 0.0396 | 0.0716 |
Brugia malayi | nuclear receptor RXR | 0.0021 | 0.0151 | 0.0273 |
Toxoplasma gondii | cathepsin CPL | 0.002 | 0.014 | 0.2306 |
Schistosoma mansoni | ran | 0.0025 | 0.0196 | 0.023 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0045 | 0.0396 | 0.0716 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0076 | 0.0724 | 1 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0025 | 0.0196 | 0.2692 |
Leishmania major | GTP-binding protein, putative | 0.0025 | 0.0196 | 0.2703 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0028 | 0.0223 | 1 |
Onchocerca volvulus | 0.002 | 0.014 | 0.0126 | |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0045 | 0.0396 | 0.0396 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0045 | 0.0396 | 0.0716 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.001 | 0.0039 | 0.053 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Mycobacterium ulcerans | hypothetical protein | 0.0159 | 0.1589 | 0.5 |
Brugia malayi | Importin beta-1 subunit | 0.0034 | 0.029 | 0.0525 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.002 | 0.014 | 0.4829 |
Echinococcus multilocularis | cpg binding protein | 0.0036 | 0.0309 | 0.0309 |
Echinococcus granulosus | cathepsin L | 0.001 | 0.0039 | 0.0046 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0007 | 0.0001 | 0.0002 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0021 | 0.0151 | 0.0178 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.002 | 0.014 | 0.014 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0021 | 0.0151 | 0.0273 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0151 | 0.0273 |
Entamoeba histolytica | cysteine proteinase, putative | 0.001 | 0.0039 | 0.1769 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0177 | 0.0321 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0021 | 0.0151 | 0.0178 |
Echinococcus granulosus | cysteine protease | 0.001 | 0.0039 | 0.0046 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0021 | 0.0151 | 0.0273 |
Trichomonas vaginalis | helicase, putative | 0.0008 | 0.0013 | 0.0588 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0021 | 0.0151 | 0.0151 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0013 | 0.0588 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0045 | 0.0396 | 0.0716 |
Plasmodium falciparum | importin beta, putative | 0.0034 | 0.029 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0021 | 0.0151 | 0.0273 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.014 | 0.1935 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0045 | 0.0396 | 0.0716 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.001 | 0.0039 | 0.0046 |
Onchocerca volvulus | 0.002 | 0.014 | 0.0126 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0151 | 0.0178 |
Entamoeba histolytica | cysteine protease, putative | 0.001 | 0.0039 | 0.1769 |
Loa Loa (eye worm) | hypothetical protein | 0.0537 | 0.5531 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0537 | 0.5531 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0021 | 0.0151 | 0.0273 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0177 | 0.0321 |
Plasmodium vivax | unspecified product | 0.001 | 0.0039 | 0.1357 |
Plasmodium vivax | vivapain-1 | 0.001 | 0.0039 | 0.1357 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0021 | 0.0151 | 0.0273 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.002 | 0.014 | 0.0165 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0071 | 0.321 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0045 | 0.0396 | 0.0716 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.014 | 0.6298 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0045 | 0.0396 | 0.0466 |
Loa Loa (eye worm) | cysteine protease | 0.002 | 0.014 | 0.0253 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.002 | 0.014 | 0.1924 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0013 | 0.0588 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | > 12.5 uM | Inhibitory activity against Leishmania infantum parasite L1 strain | ChEMBL. | 12781186 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.