Detailed information for compound 1016979

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 472.7 | Formula: C30H48O4
  • H donors: 3 H acceptors: 4 LogP: 6.67 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@]1(C)[C@@H](O)CC[C@]2([C@H]1CC[C@@]1([C@@H]2CC=C2[C@@]1(C)CC[C@@]1([C@H]2[C@@H](C)[C@@H](CC1)C)C(=O)O)C)C
  • InChi: 1S/C30H48O4/c1-18-9-14-30(25(33)34)16-15-28(5)20(24(30)19(18)2)7-8-22-26(3)12-11-23(32)27(4,17-31)21(26)10-13-29(22,28)6/h7,18-19,21-24,31-32H,8-17H2,1-6H3,(H,33,34)/t18-,19+,21-,22-,23+,24+,26+,27-,28-,29-,30+/m1/s1
  • InChiKey: NZCULBURCGAPSF-OQCQIIONSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens protein tyrosine phosphatase, non-receptor type 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum expressed protein Get druggable targets OG5_133865 All targets in OG5_133865
Echinococcus multilocularis tyrosine protein phosphatase non receptor type Get druggable targets OG5_133865 All targets in OG5_133865
Loa Loa (eye worm) protein-tyrosine phosphatase Get druggable targets OG5_133865 All targets in OG5_133865
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 Get druggable targets OG5_133865 All targets in OG5_133865
Brugia malayi Protein-tyrosine phosphatase containing protein Get druggable targets OG5_133865 All targets in OG5_133865
Schistosoma japonicum ko:K05696 protein tyrosine phosphatase, non-receptor type 1, putative Get druggable targets OG5_133865 All targets in OG5_133865
Echinococcus granulosus tyrosine protein phosphatase non receptor type Get druggable targets OG5_133865 All targets in OG5_133865
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0023 0.0003 0.0014
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.0001 0.0001
Onchocerca volvulus 0.0539 0.0465 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.011 0.0082 0.2969
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0001 0.0001
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0102 0.0074 0.0662
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0031 0.0011 0.0466
Trichomonas vaginalis ap endonuclease, putative 0.0132 0.0101 0.0395
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0024 0.0924
Mycobacterium tuberculosis Probable hydrolase 0.0308 0.0259 0.145
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0106 0.0077 0.0408
Echinococcus granulosus microtubule associated protein 2 0.0806 0.0705 0.2794
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.0022 0.086
Echinococcus multilocularis traf and tnf receptor associated protein 0.0027 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.2302 0.2045 0.8111
Brugia malayi RNA binding protein 0.0135 0.0104 0.0931
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Mycobacterium tuberculosis Putative ferredoxin reductase 0.011 0.0082 0.0431
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Giardia lamblia Hypothetical protein 0.0071 0.0047 0.0181
Schistosoma mansoni neuropeptide receptor 0.0021 0.0001 0.0005
Echinococcus multilocularis carbonic anhydrase 0.0107 0.0079 0.0079
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.0001 0.0005
Brugia malayi putative neuropeptide receptor NPR1 0.0021 0.0001 0.0011
Brugia malayi F/Y-rich N-terminus family protein 0.0042 0.002 0.0181
Brugia malayi MH2 domain containing protein 0.0247 0.0204 0.1834
Toxoplasma gondii thioredoxin reductase 0.0048 0.0026 0.1006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0012
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0027 0.0007 0.0021
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0027 0.0007 0.0026
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0001 0.0005
Brugia malayi Thioredoxin family protein 0.0071 0.0047 0.0419
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0132 0.0101 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0015 0.0058
Trypanosoma cruzi aldo/keto reductase, putative 0.0055 0.0032 0.0127
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0021 0.0001 0.0001
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.0032 0.0126
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0024 0.093
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0308 0.0259 0.2326
Schistosoma mansoni follistatin 0.0046 0.0024 0.0095
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0483 0.0416 0.1648
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Echinococcus granulosus PHD finger protein rhinoceros 0.006 0.0036 0.0144
Schistosoma mansoni microtubule-associated protein tau 0.0806 0.0705 0.2794
Schistosoma mansoni alpha-glucosidase 0.0409 0.0349 0.1385
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0018 0.0161
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0027 0.0007 0.0021
Schistosoma mansoni biogenic amine receptor 0.0021 0.0001 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0001 0.0001
Brugia malayi SPARC precursor 0.0046 0.0024 0.0215
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0008 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0046 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0019 0.0075
Brugia malayi hypothetical protein 0.0021 0.0001 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0003 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0001 0.0001
Brugia malayi G protein-coupled receptor F59B2.13 0.0021 0.0001 0.0011
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.0054 0.0213
Loa Loa (eye worm) hypothetical protein 0.0107 0.0079 0.0709
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0027 0.0007 0.0647
Leishmania major hypothetical protein, conserved 0.0027 0.0007 0.0026
Schistosoma mansoni intermediate filament proteins 0.019 0.0153 0.0605
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.0007 0.0058
Echinococcus multilocularis importin subunit beta 1 0.006 0.0036 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0001 0.0005
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0031 0.0011 0.0166
Entamoeba histolytica hypothetical protein 0.0228 0.0187 0.0736
Mycobacterium tuberculosis Conserved hypothetical protein 0.0071 0.0047 0.0231
Echinococcus multilocularis tar DNA binding protein 0.0135 0.0104 0.0104
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0087 0.0061 0.0241
Loa Loa (eye worm) beta-lactamase 0.0308 0.0259 0.2326
Loa Loa (eye worm) hypothetical protein 0.0308 0.0259 0.2326
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0091 0.0065 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0012
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0091 0.0065 0.2293
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0019 0.0072
Schistosoma mansoni potassium channel beta 0.0055 0.0032 0.0127
Brugia malayi hypothetical protein 0.1261 0.1113 1
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0023 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0079 0.0054 0.0483
Plasmodium vivax hypothetical protein, conserved 0.006 0.0036 0.1402
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0021 0.0001 0.0011
Trypanosoma brucei RNA editing exonuclease 2 0.0027 0.0007 0.0026
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0 0.0008
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.0001 0.0001
Echinococcus granulosus aldo keto reductase 0.0055 0.0032 0.0127
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0007 0.0007
Mycobacterium ulcerans hypothetical protein 0.0308 0.0259 1
Echinococcus multilocularis aldo keto reductase 0.0055 0.0032 0.0032
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.0001 0.0012
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.0032 0.0126
Loa Loa (eye worm) hypothetical protein 0.0091 0.0065 0.058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0003 0.0003
Trichomonas vaginalis importin beta-1, putative 0.0049 0.0026 0.01
Leishmania major p450 reductase, putative 0.0023 0.0003 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0193 0.0156 0.5966
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0021 0.0001 0.0012
Schistosoma mansoni pol-related 0.0055 0.0032 0.0127
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.2834 0.2522 1
Toxoplasma gondii transporter, major facilitator family protein 0.0067 0.0043 0.1663
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0025
Echinococcus granulosus tar DNA binding protein 0.0135 0.0104 0.0411
Entamoeba histolytica alcohol dehydrogenase, putative 0.0055 0.0032 0.0122
Mycobacterium tuberculosis Conserved hypothetical protein 0.0176 0.014 0.077
Schistosoma mansoni hypothetical protein 0.0021 0.0001 0.0005
Trichomonas vaginalis set domain proteins, putative 0.0539 0.0465 0.1842
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0039 0.0018 0.0368
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0046 0.0182
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0069 0.0045 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0046 0.0182
Brugia malayi Serotonin receptor 0.0021 0.0001 0.0011
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0007 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0019 0.0075
Trypanosoma cruzi p450 reductase, putative 0.0023 0.0003 0.0014
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0007 0.0058
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0089 0.0351
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0055 0.0032 0.0127
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0027 0.0007 0.0021
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0017 0.0017
Mycobacterium tuberculosis Probable esterase LipL 0.0308 0.0259 0.145
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0055 0.0032 0.113
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0021 0.0001 0.0005
Echinococcus multilocularis neutral alpha glucosidase AB 0.0105 0.0077 0.0077
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0021
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.006 0.0036 0.0144
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0001 0.0005
Echinococcus multilocularis inositol monophosphatase 1 0.0118 0.0089 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0171 0.0136 0.0534
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0021 0.0001 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0032 0.0121
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0007 0.0058
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.0007 0.0058
Echinococcus multilocularis voltage gated potassium channel subunit 0.0055 0.0032 0.0032
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0022 0.0088
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0019 0.0076
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0027 0.0007 0.0026
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0021 0.0001 0.0005
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0027 0.0007 0.0026
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0175
Echinococcus multilocularis dna polymerase kappa 0.004 0.0019 0.0019
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0045 0.0023 0.009
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Onchocerca volvulus 0.0021 0.0001 0.0008
Schistosoma mansoni ferritin 0.0027 0.0007 0.0027
Leishmania major DNA polymerase kappa, putative 0.004 0.0019 0.0075
Echinococcus multilocularis GPCR, family 2 0.0178 0.0142 0.0142
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0193 0.0156 0.0618
Plasmodium vivax SET domain protein, putative 0.0069 0.0045 0.1721
Loa Loa (eye worm) hypothetical protein 0.0067 0.0043 0.0387
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0023 0.0003 0.0003
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0021 0.0001 0.0011
Echinococcus multilocularis ferritin 0.0027 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0023 0.0086
Trypanosoma cruzi hypothetical protein, conserved 0.0744 0.0649 0.2573
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0001 0.0005
Mycobacterium ulcerans transglutaminase family protein 0.0071 0.0047 0.1691
Mycobacterium ulcerans aldehyde dehydrogenase 0.0193 0.0156 0.5966
Echinococcus granulosus neuropeptide FF receptor 2 0.0021 0.0001 0.0005
Leishmania major pantothenate kinase subunit, putative 0.0029 0.0009 0.0034
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0021 0.0001 0.0011
Echinococcus granulosus g protein coupled receptor 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0124 0.0494
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0178
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0003 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0193 0.0156 0.5966
Echinococcus multilocularis peregrin 0.0066 0.0042 0.0042
Loa Loa (eye worm) intermediate filament protein 0.019 0.0153 0.1371
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0027 0.0007 0.0021
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0107 0.0079 0.0709
Loa Loa (eye worm) carbonic anhydrase 3 0.0198 0.016 0.1441
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0032 0.0126
Brugia malayi PHD-finger family protein 0.0025 0.0005 0.0045
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0021 0.0001 0.0005
Brugia malayi sodium-independent organic anion transporter family protein 0.0067 0.0043 0.0387
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0035 0.031
Brugia malayi Bromodomain containing protein 0.0087 0.0061 0.0547
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Leishmania major hypothetical protein, conserved 0.0027 0.0007 0.0026
Echinococcus multilocularis neutral sphingomyelinase 0.0027 0.0007 0.0007
Brugia malayi Dopamine receptor protein 1 0.0021 0.0001 0.0011
Brugia malayi sodium-independent organic anion transporter family protein 0.0067 0.0043 0.0387
Schistosoma mansoni ap endonuclease 0.0132 0.0101 0.0399
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0105 0.0077 0.0694
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0003 0.0011
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0021 0.0001 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0077 0.0306
Schistosoma mansoni hypothetical protein 0.0257 0.0213 0.0845
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0055 0.0032 0.113
Schistosoma mansoni hypothetical protein 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Schistosoma mansoni myosin xvIII 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0025 0.0005 0.0045
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0006 0.0055
Onchocerca volvulus 0.0021 0.0001 0.0008
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0 0.0001
Leishmania major glycosyl hydrolase-like protein 0.0039 0.0018 0.0071
Schistosoma mansoni cpg binding protein 0.0063 0.0039 0.0156
Echinococcus granulosus g protein coupled receptor 0.0021 0.0001 0.0005
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0423 0.0362 0.3252
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0045 0.0023 0.0086
Echinococcus multilocularis neuropeptide receptor A26 0.1461 0.1291 0.1291
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0132 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0077 0.0306
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0055 0.0032 0.0123
Trypanosoma brucei unspecified product 0.004 0.0019 0.0075
Leishmania major hypothetical protein, conserved 0.0079 0.0054 0.0213
Leishmania major 4-coumarate:coa ligase-like protein 0.0055 0.0032 0.0128
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0178 0.0142 0.1279
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0001 0.0001
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0055 0.0032 0.0127
Mycobacterium tuberculosis Conserved protein 0.0308 0.0259 0.145
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0001 0.0011
Onchocerca volvulus 0.0069 0.0045 0.0941
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0024 0.0924
Mycobacterium tuberculosis Conserved protein 0.0055 0.0032 0.0147
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0021 0.0001 0.0012
Plasmodium falciparum phd finger protein, putative 0.006 0.0036 0.3606
Trypanosoma brucei hypothetical protein, conserved 0.0308 0.0259 0.1026
Schistosoma mansoni opsin-like receptor 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0018 0.0067
Mycobacterium tuberculosis Probable oxidoreductase 0.0055 0.0032 0.0147
Trypanosoma brucei glucosidase, putative 0.0105 0.0077 0.0306
Leishmania major DNA polymerase eta, putative 0.0041 0.0019 0.0076
Schistosoma mansoni hypothetical protein 0.0036 0.0015 0.0058
Brugia malayi hypothetical protein 0.0079 0.0054 0.0483
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0123 0.0093 0.0495
Echinococcus granulosus neuropeptide receptor A26 0.1461 0.1291 0.5122
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Schistosoma mansoni aldehyde dehydrogenase 0.0193 0.0156 0.0618
Onchocerca volvulus 0.0022 0.0003 0.0042
Schistosoma mansoni coup transcription factor 0.0022 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0308 0.0259 0.2326
Plasmodium vivax aldehyde reductase, putative 0.0055 0.0032 0.1241
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0055 0.0032 0.1016
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0023 0.0023
Schistosoma mansoni growth hormone secretagogue receptor 0.0021 0.0001 0.0005
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0024 0.0091
Onchocerca volvulus 0.0027 0.0007 0.0123
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0055 0.0032 0.0127
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0041 0.0019 0.0743
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0001 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0001 0.0005
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0021 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0001 0.0001
Schistosoma mansoni cpg binding protein 0.0063 0.0039 0.0156
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0019 0.0075
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0001 0.0001
Onchocerca volvulus Neuropeptide F receptor homolog 0.0021 0.0001 0.0008
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0007 0.0026
Echinococcus granulosus muscleblind protein 0.0145 0.0112 0.0445
Schistosoma mansoni alpha glucosidase 0.0105 0.0077 0.0306
Schistosoma mansoni biogenic amine receptor 0.0021 0.0001 0.0005
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0193 0.0156 0.0618
Schistosoma mansoni amine GPCR 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0023 0.0204
Echinococcus granulosus cpg binding protein 0.0063 0.0039 0.0156
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0118 0.106
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.0001 0.0005
Echinococcus granulosus g protein coupled receptor 0.0021 0.0001 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0019 0.0072
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0001 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0032 0.113
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.0089 0.3427
Leishmania major mitochondrial DNA polymerase beta 0.0334 0.0282 0.1119
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0024 0.0215
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0055 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0027 0.0007 0.0026
Loa Loa (eye worm) hypothetical protein 0.0206 0.0167 0.1503
Echinococcus granulosus zinc finger protein 0.0028 0.0008 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0019 0.0075
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0001 0.0005
Schistosoma mansoni ferritin light chain 0.0027 0.0007 0.0027
Echinococcus granulosus follistatin 0.0046 0.0024 0.0095
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0055 0.0032 0.0127
Loa Loa (eye worm) hypothetical protein 0.0308 0.0259 0.2326
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0003 0.0025
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0024 0.0091
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.2834 0.2522 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0055 0.0032 0.0123
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0021 0.0001 0.0012
Entamoeba histolytica acyl-CoA synthetase, putative 0.0055 0.0032 0.0123
Loa Loa (eye worm) RNA binding protein 0.0135 0.0104 0.0931
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0087 0.0061 0.0061
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0027 0.0007 0.0021
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0054 0.5339
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0001 0.0001
Loa Loa (eye worm) histone methyltransferase 0.002 0.0001 0.0009
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0 0.0001
Schistosoma mansoni hypothetical protein 0.0824 0.0721 0.2859
Echinococcus granulosus aldo keto reductase 0.0055 0.0032 0.0127
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0026 0.0103
Schistosoma mansoni ran 0.0044 0.0022 0.0088
Echinococcus multilocularis peptidase Clp (S14 family) 0.006 0.0036 0.0036
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0091 0.0065 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Trypanosoma cruzi mitochondrial protein 99, putative 0.0027 0.0007 0.0026
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0007 0.0029
Onchocerca volvulus 0.0027 0.0007 0.0123
Onchocerca volvulus 0.0055 0.0032 0.0674
Echinococcus granulosus peregrin 0.0066 0.0042 0.0166
Trichomonas vaginalis alpha-glucosidase, putative 0.0105 0.0077 0.0302
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0021 0.0001 0.0011
Onchocerca volvulus 0.0206 0.0167 0.3582
Loa Loa (eye worm) agrin synaptic family protein 0.0046 0.0024 0.0215
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0178
Echinococcus granulosus agrin 0.0046 0.0024 0.0095
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0055 0.0032 0.0123
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0196 0.0158 0.0627
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.0022 0.02
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0003 0.0011
Echinococcus granulosus traf and tnf receptor associated protein 0.0027 0.0007 0.0026
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0007 0.0026
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0055 0.0032 0.0032
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.0054 0.2075
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0065 0.0041 0.0163
Loa Loa (eye worm) hypothetical protein 0.0102 0.0075 0.067
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.0032 0.0032
Echinococcus granulosus neuropeptide receptor 0.0021 0.0001 0.0005
Onchocerca volvulus 0.0021 0.0001 0.0008
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Brugia malayi prostaglandin transporter 0.0067 0.0043 0.0387
Schistosoma mansoni organic anion transporter 0.0067 0.0043 0.0171
Brugia malayi RE15519p 0.0021 0.0001 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0001 0.0001
Brugia malayi hypothetical protein 0.0067 0.0043 0.0387
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0007 0.0026
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0003 0.0011
Brugia malayi CXXC zinc finger family protein 0.0058 0.0035 0.031
Onchocerca volvulus 0.0021 0.0001 0.001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0228 0.0187 0.0741
Echinococcus multilocularis dnaJ subfamily B 0.0824 0.0721 0.0721
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0007 0.0026
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0019 0.0075
Leishmania major importin beta-1 subunit, putative 0.0049 0.0026 0.0104
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0032 0.0121
Trypanosoma cruzi aldo/keto reductase, putative 0.0055 0.0032 0.0127
Echinococcus multilocularis neuropeptide s receptor 0.1461 0.1291 0.1291
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.2834 0.2522 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0252
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.0001 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0105 0.0077 0.0302
Schistosoma mansoni jumonji/arid domain-containing protein 0.0078 0.0052 0.0208
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0055 0.0032 0.0032
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0001 0.0005
Giardia lamblia Aldose reductase 0.0055 0.0032 0.0123
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0198 0.016 0.1441
Schistosoma mansoni inositol monophosphatase 0.0118 0.0089 0.0351
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.0032 0.0126
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0003 0.0011
Schistosoma mansoni aldo-keto reductase 0.0055 0.0032 0.0127
Echinococcus granulosus importin subunit beta 1 0.006 0.0036 0.0144
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0021
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0198 0.016 0.0636
Plasmodium vivax hypothetical protein, conserved 0.0308 0.0259 1
Echinococcus granulosus intermediate filament protein 0.019 0.0153 0.0605
Echinococcus multilocularis synaptojanin 1 0.0027 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0067 0.0043 0.0387
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0023 0.0003 0.0014
Trichomonas vaginalis peptide N-glycanase, putative 0.0071 0.0047 0.0181
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Onchocerca volvulus 0.0257 0.0213 0.4572
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0055 0.0032 0.0127
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0091 0.0065 0.2391
Onchocerca volvulus 0.0071 0.0047 0.0986
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0019 0.0075
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0024 0.093
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0036 0.1402
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0001 0.0001
Onchocerca volvulus 0.0067 0.0043 0.0909
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0132 0.0101 0.0394
Brugia malayi hypothetical protein 0.0051 0.0029 0.0257
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0046 0.0182
Schistosoma mansoni cpg binding protein 0.0058 0.0035 0.0137
Loa Loa (eye worm) hypothetical protein 0.0186 0.0149 0.1343
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0026 0.01
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0023 0.0003 0.0014
Toxoplasma gondii aldose reductase, putative 0.0055 0.0032 0.1241
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0308 0.0259 0.145
Brugia malayi PHD-finger family protein 0.0034 0.0013 0.0115
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0023 0.0003 0.0014
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0018 0.0067
Mycobacterium tuberculosis Conserved protein 0.0071 0.0047 0.0231
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0308 0.0259 0.145
Brugia malayi beta-lactamase 0.0308 0.0259 0.2326
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0071 0.0046 0.0046
Loa Loa (eye worm) MH2 domain-containing protein 0.0247 0.0204 0.1834
Echinococcus granulosus Solute carrier organic anion transporter family 0.0067 0.0043 0.0171
Schistosoma mansoni jumonji/arid domain-containing protein 0.0078 0.0052 0.0208
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0275 0.0229 0.2059
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0032 0.0123
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0019 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0308 0.0259 0.1026
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0003 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0104 0.0411
Giardia lamblia Aldose reductase 0.0055 0.0032 0.0123
Loa Loa (eye worm) jmjC domain-containing protein 0.0123 0.0093 0.0839
Onchocerca volvulus 0.0021 0.0001 0.0008
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0003 0.0011
Echinococcus granulosus g-protein coupled receptor 0.0021 0.0001 0.0005
Brugia malayi neuropeptide F receptor 0.0021 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0046 0.0024 0.0215
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.0007 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0046 0.0182
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0308 0.0259 0.2326
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.011 0.0082 0.0431
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0069 0.0045 0.1721
Echinococcus granulosus snurportin 1 0.064 0.0556 0.2206
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0001 0.0005
Trypanosoma brucei protein kinase, putative 0.0055 0.0032 0.0126
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0019 0.0069
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.0032 0.113
Onchocerca volvulus 0.0021 0.0001 0.0008
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0023 0.0023
Mycobacterium leprae Probable lipase LipE 0.0308 0.0259 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0055 0.0032 0.0032
Leishmania major hypothetical protein, conserved 0.0027 0.0007 0.0026
Schistosoma mansoni histamine h1 receptor 0.0021 0.0001 0.0005
Brugia malayi hypothetical protein 0.0021 0.0001 0.0011
Schistosoma mansoni importin beta-1 0.006 0.0036 0.0144
Brugia malayi Glycosyl hydrolases family 31 protein 0.0475 0.0409 0.3671
Echinococcus multilocularis geminin 0.2302 0.2045 0.2045
Leishmania major cathepsin L-like protease 0.0071 0.0046 0.0182
Loa Loa (eye worm) hypothetical protein 0.019 0.0153 0.1371
Loa Loa (eye worm) hypothetical protein 0.0035 0.0014 0.0126
Mycobacterium ulcerans hypothetical protein 0.0055 0.0032 0.113
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0055 0.0032 0.0289
Mycobacterium tuberculosis Conserved protein 0.0308 0.0259 0.145
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0003 0.0025
Plasmodium falciparum DNase I-like protein, putative 0.0027 0.0007 0.0647
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0118 0.0089 0.0347
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0046 0.0182
Brugia malayi Calcitonin receptor-like protein seb-1 0.0563 0.0487 0.4377
Schistosoma mansoni cript-related 0.0027 0.0007 0.0026
Brugia malayi AMP-binding enzyme family protein 0.0055 0.0032 0.029
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0021 0.0001 0.0012
Loa Loa (eye worm) PHD-finger family protein 0.006 0.0036 0.0326
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0046 0.0182
Schistosoma mansoni hypothetical protein 0.0021 0.0001 0.0005
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0132 0.0101 0.0399
Schistosoma mansoni synaptojanin 0.0027 0.0007 0.0026
Echinococcus granulosus ubiquitin specific protease 41 0.0045 0.0023 0.009
Schistosoma mansoni carbonic anhydrase-related 0.0107 0.0079 0.0313
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0334 0.0282 0.1119
Brugia malayi beta-lactamase family protein 0.0308 0.0259 0.2326
Schistosoma mansoni neuropeptide receptor 0.0021 0.0001 0.0005
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0252
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0054 0.0213
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0001 0.0001
Leishmania major DNA polymerase eta, putative 0.0069 0.0044 0.0175
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0019 0.0068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0003 0.0025
Onchocerca volvulus 0.0055 0.0032 0.0674
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0054 0.0213
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0007 0.0058
Schistosoma mansoni amine GPCR 0.0021 0.0001 0.0005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0003 0.0011
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0021 0.0001 0.0011
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0003 0.0025
Onchocerca volvulus Alhambra homolog 0.006 0.0036 0.0763
Mycobacterium ulcerans lipase LipD 0.0308 0.0259 1
Schistosoma mansoni ran 0.0044 0.0022 0.0088
Entamoeba histolytica hypothetical protein 0.0228 0.0187 0.0736
Toxoplasma gondii hypothetical protein 0.0031 0.0011 0.0421
Trypanosoma brucei carbonic anhydrase-like protein 0.0198 0.016 0.0636
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0019 0.0075
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0018 0.0067
Schistosoma mansoni alpha-1 adrenergic receptor 0.0021 0.0001 0.0005
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0198 0.016 0.0636
Giardia lamblia hypothetical protein 0.0027 0.0007 0.0021
Loa Loa (eye worm) jmjC domain-containing protein 0.0078 0.0052 0.047
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0027 0.0007 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0104 0.0411
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0107 0.0079 0.0709
Loa Loa (eye worm) hypothetical protein 0.0046 0.0024 0.0215
Brugia malayi G-protein coupled receptor 0.0021 0.0001 0.0011
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0055 0.0032 0.0032
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0021 0.0001 0.0005
Brugia malayi GnHR receptor homolog 0.0021 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0067 0.0043 0.0387
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0132 0.0101 0.0399
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0025 0.0005 0.0019
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0132 0.0101 0.3887
Onchocerca volvulus 0.0021 0.0001 0.0008
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0021 0.0001 0.0005
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0024 0.0924
Leishmania major GTP-binding protein, putative 0.0044 0.0022 0.0088
Schistosoma mansoni survival motor neuron protein 0.0257 0.0213 0.0845
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0055 0.0032 0.1016
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0007 0.0058
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0003 0.0011
Onchocerca volvulus 0.019 0.0153 0.3267
Trichomonas vaginalis aldo/keto reductase, putative 0.0055 0.0032 0.0123
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0023 0.0003 0.0336
Schistosoma mansoni amine GPCR 0.0021 0.0001 0.0005
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0055 0.0032 0.1008
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.0022 0.0088
Loa Loa (eye worm) hypothetical protein 0.0055 0.0032 0.0289
Trichomonas vaginalis aldo/keto reductase, putative 0.0055 0.0032 0.0123
Brugia malayi jmjC domain containing protein 0.0078 0.0052 0.047
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Brugia malayi NADH-dependent xylose reductase 0.0055 0.0032 0.0289
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Schistosoma mansoni jumonji domain containing protein 0.0156 0.0122 0.0484
Brugia malayi sodium-independent organic anion transporter family protein 0.0067 0.0043 0.0387
Brugia malayi hypothetical protein 0.0021 0.0001 0.0012
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0021 0.0001 0.0001
Onchocerca volvulus 0.0055 0.0032 0.0674
Loa Loa (eye worm) G protein alpha subunit 3 0.0021 0.0001 0.0012
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0001 0.0005
Schistosoma mansoni transcription factor LCR-F1 0.0228 0.0187 0.0741
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0118 0.0118
Onchocerca volvulus Huntingtin homolog 0.051 0.044 0.9455
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0198 0.016 0.1441
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.2834 0.2522 1
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.2834 0.2522 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0062 0.0553
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0055 0.0032 0.0289
Onchocerca volvulus 0.0308 0.0259 0.5553
Echinococcus granulosus carbonic anhydrase 0.0107 0.0079 0.0313
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0021 0.0001 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0018 0.0065
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0034 0.0135
Echinococcus granulosus peptide allatostatin:somatostatin 0.0021 0.0001 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0003 0.0025
Mycobacterium ulcerans hypothetical protein 0.0071 0.0047 0.1691
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0003 0.0025
Onchocerca volvulus 0.0021 0.0001 0.0008
Echinococcus multilocularis aldo keto reductase 0.0055 0.0032 0.0032
Mycobacterium tuberculosis Probable dehydrogenase 0.011 0.0082 0.0431
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.0022 0.2212
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0001 0.0001
Echinococcus granulosus serotonin receptor 0.0021 0.0001 0.0005
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0021 0.0001 0.0001
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0003 0.0042
Echinococcus granulosus beta LACTamase domain containing family member 0.0308 0.0259 0.1026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0046 0.0182
Leishmania major hypothetical protein, conserved 0.0308 0.0259 0.1026
Onchocerca volvulus 0.0021 0.0001 0.001
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0007 0.0058
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Schistosoma mansoni lamin 0.019 0.0153 0.0605
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0007 0.0058
Trichomonas vaginalis esterase, putative 0.0308 0.0259 0.1022
Plasmodium falciparum acyl-CoA synthetase 0.0041 0.002 0.1966
Loa Loa (eye worm) transcription factor SMAD2 0.0247 0.0204 0.1834
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0046 0.0182
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0027 0.0007 0.006
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0027 0.0007 0.0026
Schistosoma mansoni agrin 0.0046 0.0024 0.0095
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0124 0.0494
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0023 0.0204
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0019 0.0075
Loa Loa (eye worm) inositol-1 0.0118 0.0089 0.0796
Brugia malayi CCR4 0.0027 0.0007 0.006
Echinococcus multilocularis g-protein coupled receptor 0.0021 0.0001 0.0001
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0027 0.0007 0.0647
Loa Loa (eye worm) hypothetical protein 0.0178 0.0142 0.1279
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0054 0.5339
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0001 0.0005
Brugia malayi Tachykinin-like peptides receptor 99D 0.0021 0.0001 0.0011
Plasmodium falciparum glutathione reductase 0.0048 0.0026 0.2588
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0001 0.0005
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0003 0.0011
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0308 0.0259 1
Plasmodium falciparum importin beta, putative 0.006 0.0036 0.3622
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0019 0.0075
Echinococcus granulosus histone lysine methyltransferase setb 0.0087 0.0061 0.0241
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0058
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0018 0.0066
Mycobacterium ulcerans hypothetical protein 0.0176 0.014 0.5367
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.2834 0.2522 1
Brugia malayi Inositol-1 0.0118 0.0089 0.0796
Loa Loa (eye worm) hypothetical protein 0.0055 0.0032 0.029
Trypanosoma cruzi importin beta-1 subunit, putative 0.0049 0.0026 0.0104
Trichomonas vaginalis sulfite reductase, putative 0.0023 0.0003 0.0009
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0027 0.0007 0.0022
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0118 0.0468
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0021 0.0001 0.0005
Brugia malayi Muscleblind-like protein 0.0145 0.0112 0.1009
Entamoeba histolytica acyl-CoA synthetase, putative 0.0055 0.0032 0.0123
Leishmania major hypothetical protein, conserved 0.0744 0.0649 0.2573
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0021 0.0001 0.0005
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.019 0.0153 0.1371
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0055 0.0032 0.0127
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0198 0.016 0.0636
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0046 0.0182
Onchocerca volvulus Putative neutral sphingomyelinase 0.0027 0.0007 0.0123
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0027 0.0007 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0025
Loa Loa (eye worm) hypothetical protein 0.0145 0.0112 0.1009
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0091 0.0065 0.6157
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0029 0.0009 0.0034
Echinococcus granulosus tumor protein p63 0.1407 0.1243 0.493
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0003 0.0131
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0091 0.0065 0.2493
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0055 0.0032 0.113
Trypanosoma cruzi mitochondrial protein 99, putative 0.0027 0.0007 0.0026
Loa Loa (eye worm) hypothetical protein 0.0563 0.0487 0.4377
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0025 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0091 0.0065 0.0581
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.051 0.044 0.3954
Brugia malayi Importin beta-1 subunit 0.006 0.0036 0.0327
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0023 0.009
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0003 0.0025
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0003 0.0042
Loa Loa (eye worm) oxidoreductase 0.0055 0.0032 0.0289
Onchocerca volvulus Putative organic anion transporter 0.0067 0.0043 0.0909
Trichomonas vaginalis inositol monophosphatase, putative 0.0118 0.0089 0.0347
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.0001 0.0012
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0015 0.0015
Trypanosoma cruzi DNA polymerase eta, putative 0.0069 0.0044 0.0175
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0055 0.0032 0.0032
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0132 0.0101 0.3804
Brugia malayi exodeoxyribonuclease III family protein 0.0132 0.0101 0.0904
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0105 0.0077 0.0301
Loa Loa (eye worm) hypothetical protein 0.006 0.0036 0.0327
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0025
Leishmania major prostaglandin f synthase, putative 0.0055 0.0032 0.0127
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0055 0.0032 0.0289
Giardia lamblia Inositol 5-phosphatase 4 0.0027 0.0007 0.0021
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0055 0.0032 0.0148
Toxoplasma gondii hypothetical protein 0.0054 0.0031 0.1199
Loa Loa (eye worm) oxidoreductase 0.0055 0.0032 0.0289
Schistosoma mansoni ferritin 0.0027 0.0007 0.0027
Brugia malayi putative neuropeptide receptor 0.0021 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0025
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0027 0.0007 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0001 0.0005
Echinococcus granulosus hypothetical protein 0.0021 0.0001 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0008 0.0031
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0019 0.0171
Loa Loa (eye worm) hypothetical protein 0.1261 0.1113 1
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0112 0.0112
Toxoplasma gondii hypothetical protein 0.0107 0.0079 0.305
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0019 0.0608
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0025
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0021 0.0001 0.0001
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0021 0.0001 0.0012
Schistosoma mansoni hypothetical protein 0.0178 0.0142 0.0564
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0027 0.0007 0.0647
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0003 0.0011
Onchocerca volvulus 0.0067 0.0043 0.0909
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0046 0.0182
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0107 0.0079 0.0709
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.011 0.0082 0.0431
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0105 0.0077 0.0301
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0055 0.0032 0.1241
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0021 0.0001 0.0001
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.0032 0.0126
Schistosoma mansoni apoferritin-2 0.0027 0.0007 0.0027
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0091 0.0065 0.0065
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0067 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Echinococcus granulosus carbonic anhydrase 0.0107 0.0079 0.0313
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0027 0.0007 0.0026
Brugia malayi latrophilin 2 splice variant baaae 0.0385 0.0327 0.2943
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0198 0.016 0.1441
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0423 0.0362 0.0362
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.0007 0.0252
Mycobacterium tuberculosis Conserved protein 0.0308 0.0259 0.145
Echinococcus multilocularis X box binding protein 1 0.0319 0.0268 0.0268
Schistosoma mansoni apoferritin-2 0.0027 0.0007 0.0027
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0027 0.0007 0.0021
Schistosoma mansoni hypothetical protein 0.0228 0.0187 0.0741
Echinococcus multilocularis serotonin receptor 0.0021 0.0001 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0308 0.0259 0.1022
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.0001 0.0005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0025 0.0098
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0132 0.0101 0.0904
Loa Loa (eye worm) hypothetical protein 0.0088 0.0062 0.0553
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0132 0.0101 0.0399
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0024 0.0215
Echinococcus multilocularis neuropeptide FF receptor 2 0.0021 0.0001 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0308 0.0259 0.1022
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0031 0.0011 0.1083
Leishmania major 4-coumarate:coa ligase-like protein 0.0055 0.0032 0.0128
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0055 0.0032 0.0032
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0046 0.0182
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0019 0.1844
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0003 0.0025
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0021 0.0001 0.0005
Echinococcus multilocularis lysine specific demethylase 5A 0.0072 0.0048 0.0048
Onchocerca volvulus Huntingtin homolog 0.051 0.044 0.9455
Loa Loa (eye worm) hypothetical protein 0.0046 0.0024 0.0215
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.006 0.0036 0.1175
Echinococcus multilocularis G protein coupled receptor 139 0.0021 0.0001 0.0001
Plasmodium vivax importin-beta 2, putative 0.006 0.0036 0.1408
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0023 0.009
Giardia lamblia DINP protein human, muc B family 0.004 0.0019 0.0071
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0132 0.0101 0.0541
Entamoeba histolytica hypothetical protein 0.0049 0.0026 0.0099
Echinococcus granulosus carbonic anhydrase 0.0107 0.0079 0.0313
Schistosoma mansoni alpha-glucosidase 0.0409 0.0349 0.1385
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.064 0.0556 0.4998
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0003 0.0011
Brugia malayi steroid hormone receptor 0.0022 0.0003 0.0025
Echinococcus granulosus alpha 1A adrenergic receptor 0.0021 0.0001 0.0005
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0001 0.0005
Loa Loa (eye worm) oxidoreductase 0.0055 0.0032 0.0289
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.0007 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0001 0.0005
Echinococcus granulosus allatostatin A receptor 0.0021 0.0001 0.0005
Brugia malayi G protein-coupled receptor 0.0021 0.0001 0.0011
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0001 0.0005
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0027 0.0007 0.0007
Echinococcus multilocularis Transglutaminase 0.0071 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0003 0.0003
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0023 0.0003 0.0003
Brugia malayi hypothetical protein 0.051 0.044 0.3954
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0026 0.1006
Echinococcus granulosus lamin dm0 0.019 0.0153 0.0605
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.0001 0.0005
Onchocerca volvulus 0.019 0.0153 0.3267
Brugia malayi ImpB/MucB/SamB family protein 0.0069 0.0044 0.0397
Trypanosoma brucei unspecified product 0.0028 0.0008 0.0031
Echinococcus multilocularis G-protein coupled receptor, putative 0.0021 0.0001 0.0001
Echinococcus multilocularis muscleblind protein 0.0145 0.0112 0.0112
Schistosoma mansoni cellular tumor antigen P53 0.0206 0.0167 0.0663
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 0.0282 0.1119
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.0032 0.1223
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0019 0.0071
Echinococcus granulosus lamin 0.019 0.0153 0.0605
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0104 0.0411
Onchocerca volvulus 0.0021 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0055 0.0032 0.029
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.0001 0.0005
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0007 0.0026
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0021 0.0001 0.0001
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.0001 0.0005
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0021 0.0001 0.0001
Toxoplasma gondii aldehyde dehydrogenase 0.0193 0.0156 0.602
Brugia malayi hypothetical protein 0.0228 0.0187 0.1679
Trichomonas vaginalis ran, putative 0.0044 0.0022 0.0084
Loa Loa (eye worm) TYRA-2 protein 0.0021 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0053 0.003 0.0268
Treponema pallidum bacterioferrin (TpF1) 0.0027 0.0007 0.0021
Entamoeba histolytica aldose reductase, putative 0.0055 0.0032 0.0122
Entamoeba histolytica aldose reductase, putative 0.0055 0.0032 0.0122
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0176 0.014 0.1259
Brugia malayi intermediate filament protein 0.019 0.0153 0.1371
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.0001 0.0005
Echinococcus granulosus jumonji domain containing protein 0.0083 0.0057 0.0227
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0017 0.0068
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0021 0.0001 0.0001
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.0032 0.0285
Loa Loa (eye worm) hypothetical protein 0.0087 0.0061 0.0547
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0483 0.0416 0.1648
Mycobacterium tuberculosis Probable lipase LipD 0.0308 0.0259 0.145
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0021 0.0001 0.0012
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0003 0.0011
Echinococcus granulosus voltage gated potassium channel subunit 0.0055 0.0032 0.0127
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0019 0.0608
Leishmania major cytochrome P450 reductase, putative 0.0021 0.0001 0.0004
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0045 0.0023 0.009
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0021 0.0001 0.0011
Echinococcus granulosus inositol monophosphatase 1 0.0118 0.0089 0.0351
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0105 0.0077 0.0302
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0001 0.0005
Echinococcus multilocularis allatostatin A receptor 0.0021 0.0001 0.0001
Plasmodium falciparum thioredoxin reductase 0.0048 0.0026 0.2588
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0193 0.0156 0.0858
Schistosoma mansoni cytochrome P450 reductase 0.0023 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0178
Echinococcus granulosus 7TM GPCR rhodopsin 0.0021 0.0001 0.0005
Leishmania major carbonic anhydrase-like protein 0.0198 0.016 0.0636
Schistosoma mansoni carbonic anhydrase-related 0.0107 0.0079 0.0313
Schistosoma mansoni adenoreceptor 0.0021 0.0001 0.0005
Echinococcus granulosus GPCR family 2 0.0178 0.0142 0.0564
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0069 0.0045 0.0177
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0071 0.0046 0.0183
Brugia malayi hypothetical protein 0.0021 0.0001 0.0011
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0022 0.0088
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0001 0.0011
Brugia malayi hypothetical protein 0.0021 0.0001 0.0011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0095 0.0376
Leishmania major cathepsin L-like protease 0.0071 0.0046 0.0182
Brugia malayi Glycosyl hydrolases family 31 protein 0.0105 0.0077 0.0694
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0003 0.0011
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0228 0.0187 0.0187
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.0032 0.0126
Brugia malayi hypothetical protein 0.0021 0.0001 0.0011
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0118 0.0089 0.3421
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0003 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0003 0.0025
Echinococcus granulosus G protein coupled receptor 139 0.0021 0.0001 0.0005
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0007 0.0058
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0055 0.0032 0.0148
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0032 0.0129
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0024 0.0215
Brugia malayi nuclear hormone receptor 0.0022 0.0003 0.0025
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0019 0.0075
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0132 0.0101 0.0395
Echinococcus granulosus neuropeptide receptor 0.0021 0.0001 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0308 0.0259 0.1022
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0055 0.0032 0.1241
Brugia malayi Thioredoxin reductase 0.0048 0.0026 0.0234
Echinococcus multilocularis serotonin receptor 0.0021 0.0001 0.0001
Echinococcus granulosus 7tm_1 domain containing protein 0.0021 0.0001 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0001 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0003 0.0025
Giardia lamblia PHD finger protein 15 0.006 0.0036 0.014
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0031
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0027 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0107 0.0079 0.0313
Echinococcus multilocularis expressed protein 0.0027 0.0007 0.0007
Onchocerca volvulus 0.0067 0.0043 0.0909
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0019 0.0075
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0135 0.0104 0.0931
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0041 0.002 0.0639
Entamoeba histolytica alcohol dehydrogenase, putative 0.0055 0.0032 0.0122
Schistosoma mansoni nocturnin 0.0027 0.0007 0.0026
Loa Loa (eye worm) glutathione reductase 0.0048 0.0026 0.0234
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0019 0.0171
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0055 0.0032 0.0127
Trichomonas vaginalis alpha-glucosidase, putative 0.0105 0.0077 0.0302
Onchocerca volvulus 0.0021 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0178
Loa Loa (eye worm) hypothetical protein 0.0046 0.0024 0.0215
Trypanosoma brucei hypothetical protein, conserved 0.0744 0.0649 0.2573
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0036 0.1402
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0047 0.0025 0.0225
Brugia malayi Dopamine receptor 0.0021 0.0001 0.0011
Trypanosoma brucei importin beta-1 subunit, putative 0.006 0.0036 0.0144
Trypanosoma cruzi aldo-keto reductase 0.0055 0.0032 0.0127
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0023 0.0003 0.0014
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0007 0.0026
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0018 0.0065
Trypanosoma cruzi MFS transporter, putative 0.0067 0.0043 0.0171
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0018 0.0067
Echinococcus multilocularis orexin receptor type 2 0.0021 0.0001 0.0001
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0118 0.0089 0.0346
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0001 0.0005
Schistosoma mansoni peptidase Clp (S14 family) 0.0091 0.0065 0.0256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0003 0.0025
Toxoplasma gondii protease inhibitor PI2 0.0046 0.0024 0.0924
Schistosoma mansoni biogenic amine receptor 0.0021 0.0001 0.0005
Echinococcus multilocularis aldo keto reductase 0.0055 0.0032 0.0032
Brugia malayi FAD binding domain containing protein 0.0023 0.0003 0.0031
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0024 0.0215
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0041 0.002 0.0076
Mycobacterium leprae conserved hypothetical protein 0.0308 0.0259 1
Loa Loa (eye worm) oxidoreductase 0.0055 0.0032 0.0289
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0055 0.0032 0.0289
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0018 0.0067
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0001 0.0005
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0046 0.0182
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0032 0.0126
Echinococcus multilocularis lysosomal alpha glucosidase 0.0475 0.0409 0.0409
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0091 0.0065 0.0257
Toxoplasma gondii exonuclease III APE 0.0132 0.0101 0.3887
Loa Loa (eye worm) hypothetical protein 0.0055 0.0032 0.029
Echinococcus granulosus neutral sphingomyelinase 0.0027 0.0007 0.0026
Echinococcus multilocularis ubiquitin specific protease 41 0.0045 0.0023 0.0023
Onchocerca volvulus 0.0021 0.0001 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0104 0.0411
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0483 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0067 0.0043 0.0387
Loa Loa (eye worm) latrophilin receptor protein 2 0.0178 0.0142 0.1279
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0021 0.0001 0.0005
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0019 0.0075
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0178 0.0142 0.0564
Echinococcus granulosus geminin 0.2302 0.2045 0.8111
Echinococcus multilocularis aldo keto reductase 0.0055 0.0032 0.0032
Brugia malayi secreted modular calcium-binding protein 1 0.0046 0.0024 0.0215
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0018 0.0067
Mycobacterium leprae Conserved hypothetical protein 0.0071 0.0047 0.1584
Schistosoma mansoni hypothetical protein 0.0178 0.0142 0.0564
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0003 0.0003
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0046 0.0024 0.0215
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0067 0.0043 0.0043
Brugia malayi hypothetical protein 0.0067 0.0043 0.0387
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0032 0.113
Schistosoma mansoni amine GPCR 0.0021 0.0001 0.0005
Echinococcus multilocularis dro:myosuppressin receptor 0.0021 0.0001 0.0001
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0001 0.0011
Brugia malayi AF-10 protein 0.002 0 0.0002
Echinococcus multilocularis survival motor neuron protein 1 0.1261 0.1113 0.1113
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0044 0.0022 0.0084
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0178 0.0142 0.0142
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0091 0.0065 0.6165
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0027 0.0007 0.0026
Mycobacterium ulcerans bacterioferritin BfrB 0.0027 0.0007 0.0127
Giardia lamblia Rrm3p helicase 0.2834 0.2522 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0003 0.0011
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0021 0.0001 0.0012
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0024 0.093
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0118 0.0089 0.0347
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0027 0.0007 0.0026
Trichomonas vaginalis D-aminoacylase, putative 0.0308 0.0259 0.1022
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0067 0.0043 0.0387
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0058
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0021 0.0001 0.0001
Trichomonas vaginalis ferritin, putative 0.0027 0.0007 0.0022
Schistosoma mansoni carbonic anhydrase-related 0.0107 0.0079 0.0313
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0055 0.0032 0.1241
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0055 0.0032 0.0127
Loa Loa (eye worm) FAD binding domain-containing protein 0.0023 0.0003 0.0031
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0091 0.0065 0.2493
Schistosoma mansoni hypothetical protein 0.0071 0.0047 0.0185
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0032 0.0121
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0475 0.0409 0.3671
Schistosoma mansoni hypothetical protein 0.064 0.0556 0.2206
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0055 0.0032 0.0127
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0055 0.0032 0.0123
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0032 0.0126
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0023 0.0003 0.0014
Echinococcus granulosus somatostatin receptor 0.0021 0.0001 0.0005
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Plasmodium vivax glutathione reductase, putative 0.0048 0.0026 0.1006
Echinococcus granulosus tachykinin peptides receptor 99D 0.0021 0.0001 0.0005
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0027 0.0007 0.0021
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0483 0.0416 0.3734
Onchocerca volvulus 0.0055 0.0032 0.0678
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0423 0.0362 0.3252
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.0032 0.0032
Entamoeba histolytica hypothetical protein, conserved 0.2834 0.2522 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0055 0.0032 0.0123
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0021
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0107 0.0079 0.0709
Schistosoma mansoni organic anion transporter 0.0067 0.0043 0.0171
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0025
Onchocerca volvulus 0.0021 0.0001 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0483 0.0416 0.1648
Echinococcus multilocularis jumonji domain containing protein 0.0083 0.0057 0.0057
Brugia malayi RNA recognition motif domain containing protein 0.0135 0.0104 0.0931
Echinococcus multilocularis carbonic anhydrase 0.0107 0.0079 0.0079
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0252
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0027 0.0007 0.0021
Mycobacterium ulcerans oxidoreductase 0.0055 0.0032 0.1122
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Schistosoma mansoni hypothetical protein 0.0178 0.0142 0.0564
Echinococcus granulosus dro:myosuppressin receptor 0.0021 0.0001 0.0005
Onchocerca volvulus Putative organic anion transporter 0.0067 0.0043 0.0909
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0027 0.0007 0.0026
Schistosoma mansoni hypothetical protein 0.0178 0.0142 0.0564
Schistosoma mansoni ferritin 0.0027 0.0007 0.0027
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0003 0.0003
Echinococcus multilocularis musashi 0.019 0.0153 0.0153
Echinococcus multilocularis lamin 0.019 0.0153 0.0153
Brugia malayi Latrophilin receptor protein 2 0.0178 0.0142 0.1279
Treponema pallidum exodeoxyribonuclease (exoA) 0.0132 0.0101 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0252
Mycobacterium tuberculosis Long conserved protein 0.0071 0.0047 0.0231
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0055 0.0032 0.0127
Echinococcus granulosus X box binding protein 1 0.0319 0.0268 0.1064
Echinococcus multilocularis cpg binding protein 0.0063 0.0039 0.0039
Echinococcus granulosus orexin receptor type 2 0.0021 0.0001 0.0005
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0563 0.0487 0.4377
Schistosoma mansoni opsin-like receptor 0.0021 0.0001 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0018 0.0067
Trichomonas vaginalis alpha-glucosidase, putative 0.0105 0.0077 0.0302
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0001 0.0001
Echinococcus granulosus fmrfamide receptor 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0043 0.0387
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0025 0.0098
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0001 0.0001
Onchocerca volvulus 0.0021 0.0001 0.0008
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.0022 0.02
Trichomonas vaginalis alpha-glucosidase, putative 0.0105 0.0077 0.0302
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0055 0.0032 0.0123
Loa Loa (eye worm) hypothetical protein 0.051 0.044 0.3954
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0001 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0483 0.0416 0.1648
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0025 0.0098
Trypanosoma brucei trypanothione reductase 0.0048 0.0026 0.0103
Mycobacterium tuberculosis Probable oxidoreductase 0.0123 0.0093 0.0495
Toxoplasma gondii HEAT repeat-containing protein 0.006 0.0036 0.1408
Echinococcus multilocularis tumor protein p63 0.1407 0.1243 0.1243
Loa Loa (eye worm) hypothetical protein 0.0385 0.0327 0.2943
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.006 0.0036 0.0171
Toxoplasma gondii aldo-keto reductase 0.0055 0.0032 0.1241
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0019 0.0075
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0252
Onchocerca volvulus 0.0067 0.0043 0.0909
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.2834 0.2522 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0003 0.0003
Onchocerca volvulus 0.0055 0.0032 0.0674
Toxoplasma gondii ABC1 family protein 0.0308 0.0259 1
Onchocerca volvulus 0.0067 0.0043 0.0909
Brugia malayi Cytochrome P450 family protein 0.0026 0.0006 0.0055
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.0032 0.0126
Echinococcus granulosus neuropeptide s receptor 0.1461 0.1291 0.5122
Echinococcus granulosus hypothetical protein 0.0055 0.0032 0.0127
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0106 0.0077 0.2806
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Leishmania major RNA-editing complex protein MP100, putative 0.0027 0.0007 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0023 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.0744 0.0649 0.2573
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0105 0.0077 0.2983
Echinococcus granulosus peptidase Clp S14 family 0.006 0.0036 0.0144
Echinococcus multilocularis zinc finger protein 0.0028 0.0008 0.0008
Leishmania major trypanothione reductase 0.0048 0.0026 0.0103
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0021 0.0001 0.0001
Leishmania major endonuclease/exonuclease protein-like protein 0.0027 0.0007 0.0026
Trichomonas vaginalis maltase-glucoamylase, putative 0.0105 0.0077 0.0302
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0001 0.0005
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0067 0.0043 0.0171
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.2834 0.2522 1
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0118 0.0089 0.8715
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0055 0.0032 0.0289
Schistosoma mansoni hypothetical protein 0.0319 0.0268 0.1064
Brugia malayi AKH receptor 0.0021 0.0001 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0019 0.0075
Brugia malayi Serotonin receptor 0.0021 0.0001 0.0011
Echinococcus multilocularis PHD finger protein rhinoceros 0.006 0.0036 0.0036
Mycobacterium leprae Possible oxidoreductase 0.0055 0.0032 0.1008
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0423 0.0362 0.1435
Schistosoma mansoni aldo-keto reductase 0.0055 0.0032 0.0127
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0021 0.0001 0.0005
Schistosoma mansoni GTP-binding protein alpha subunit 0.0021 0.0001 0.0005
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0091 0.0065 0.6414
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0003 0.0025
Onchocerca volvulus 0.0055 0.0032 0.0674
Schistosoma mansoni carbonic anhydrase 0.0107 0.0079 0.0313
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.2834 0.2522 0.2522
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0046 0.0182
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0055 0.0032 0.0127
Echinococcus multilocularis beta LACTamase domain containing family member 0.0308 0.0259 0.0259
Onchocerca volvulus 0.0046 0.0024 0.0497
Loa Loa (eye worm) hypothetical protein 0.0107 0.0079 0.0709
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0018 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0008 0.0031
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0025 0.0098
Onchocerca volvulus 0.0058 0.0035 0.0726
Plasmodium vivax exodeoxyribonuclease III, putative 0.0027 0.0007 0.0252
Schistosoma mansoni neuropeptide f receptor 76f 0.0021 0.0001 0.0005
Onchocerca volvulus 0.0055 0.0032 0.0674
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0019 0.007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0132 0.0101 0.0399
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0067 0.0043 0.0387
Schistosoma mansoni hypothetical protein 0.2834 0.2522 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.0032 0.0126
Echinococcus multilocularis carbonic anhydrase 0.0107 0.0079 0.0079
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0001 0.0001
Schistosoma mansoni synaptojanin 0.0027 0.0007 0.0026
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0089 0.0351
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0031 0.0011 0.0421
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0001 0.0001
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0158 0.0124 0.0494
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0196 0.0158 0.0158
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 0.0282 0.1119
Brugia malayi hypothetical protein 0.0021 0.0001 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0018 0.0065
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0021 0.0001 0.0005
Echinococcus multilocularis agrin 0.0046 0.0024 0.0024
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0021 0.0001 0.0001
Mycobacterium ulcerans beta-lactamase 0.0308 0.0259 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0023 0.0085
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0039 0.0018 0.0071
Loa Loa (eye worm) TAR-binding protein 0.0135 0.0104 0.0931
Plasmodium falciparum carbonic anhydrase 0.0107 0.0079 0.7846
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0045 0.0023 0.009
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.011 0.0082 0.0431
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0001 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0055 0.0032 0.113
Loa Loa (eye worm) hypothetical protein 0.006 0.0036 0.0326
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0007 0.0058
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0058
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0252
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0025
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0257 0.0213 0.1916
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0026 0.01
Entamoeba histolytica aldose reductase, putative 0.0055 0.0032 0.0122
Leishmania major alpha glucosidase II subunit, putative 0.0105 0.0077 0.0306
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0001 0.0005
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0019 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0001 0.0005
Trichomonas vaginalis ap endonuclease, putative 0.0132 0.0101 0.0395
Trypanosoma brucei glycosyl hydrolase-like protein 0.0039 0.0018 0.0071
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0027 0.0007 0.0026
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.0007 0.0252
Schistosoma mansoni neuropeptide receptor 0.0021 0.0001 0.0005
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0123 0.0093 0.0495
Onchocerca volvulus Putative organic anion transporter 0.0067 0.0043 0.0909
Plasmodium falciparum nitric oxide synthase, putative 0.0023 0.0003 0.0343
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0021 0.0001 0.0005
Entamoeba histolytica hypothetical protein 0.0228 0.0187 0.0736
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0023 0.0086
Onchocerca volvulus 0.0308 0.0259 0.5553
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0132 0.0101 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0123 0.0093 0.3406
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0027 0.0007 0.0026
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0007 0.0026
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0055 0.0032 0.0032
Echinococcus granulosus dna polymerase eta 0.0069 0.0044 0.0175
Brugia malayi G-protein coupled receptor 0.0021 0.0001 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0019 0.0075
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0483 0.0416 0.3734
Brugia malayi RNA, U transporter 1 0.0171 0.0135 0.1217
Leishmania major cathepsin L-like protease 0.0071 0.0046 0.0182
Loa Loa (eye worm) oxidoreductase 0.0055 0.0032 0.0289
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0002 0.0022
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0026 0.0234
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0023 0.0003 0.0014
Echinococcus multilocularis deoxyribonuclease 1 2 0.0027 0.0007 0.0007
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0024 0.0095
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0001 0.0001
Brugia malayi neuropeptide F receptor 0.0021 0.0001 0.0011
Schistosoma mansoni zinc finger protein 0.0028 0.0008 0.0031
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0021 0.0001 0.0012
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0001 0.0011
Trypanosoma brucei importin beta-1 subunit, putative 0.006 0.0036 0.0144
Plasmodium falciparum aldo-keto reductase, putative 0.0055 0.0032 0.3192
Brugia malayi AMP-binding enzyme family protein 0.0055 0.0032 0.029
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0001 0.0005
Schistosoma mansoni hypothetical protein 0.0022 0.0002 0.001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0001 0.0001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0003 0.0003
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0091 0.0065 0.2391
Echinococcus granulosus sex peptide receptor 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0069 0.0044 0.0397
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0118 0.0089 0.3332
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Echinococcus multilocularis microtubule associated protein 2 0.0806 0.0705 0.0705
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0055 0.0032 0.0032
Brugia malayi Melatonin receptor type 1A 0.0021 0.0001 0.0011
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0473 0.0407 0.3657
Loa Loa (eye worm) melatonin receptor type 1A 0.0021 0.0001 0.0011
Brugia malayi Dopamine receptor protein 2 0.0021 0.0001 0.0011
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0003 0.0025
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0026 0.0112
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0012
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0385 0.0327 0.1299
Trypanosoma brucei prostaglandin f synthase 0.0055 0.0032 0.0127
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0027 0.0007 0.0001
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0021 0.0001 0.0001
Echinococcus granulosus expressed protein 0.0021 0.0001 0.0005
Brugia malayi flavodoxin family protein 0.0023 0.0003 0.0031
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0023 0.0003 0.0014
Onchocerca volvulus 0.0021 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0107 0.0079 0.0709
Trypanosoma brucei aldo/keto reductase, putative 0.0055 0.0032 0.0127
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0001 0.0004
Brugia malayi Probable ATP-dependent helicase DHX35 0.0035 0.0014 0.0126
Onchocerca volvulus 0.0021 0.0001 0.001
Schistosoma mansoni DNA polymerase eta 0.0069 0.0044 0.0175
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0036 0.0015 0.0061
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0023 0.0086
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0089 0.0351
Entamoeba histolytica DNA repair and recombination protein, putative 0.2834 0.2522 1
Schistosoma mansoni lamin 0.019 0.0153 0.0605
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0003 0.0025
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0001 0.0005
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0023 0.009
Loa Loa (eye worm) hypothetical protein 0.0308 0.0259 0.2326
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0001 0.0005
Echinococcus granulosus expressed protein 0.0027 0.0007 0.0027
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0003 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0003 0.0025
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0021 0.0001 0.0008
Mycobacterium leprae Conserved hypothetical protein 0.0071 0.0047 0.1584
Echinococcus multilocularis somatostatin receptor 0.0021 0.0001 0.0001
Brugia malayi MAP kinase sur-1 0.0055 0.0032 0.0285
Trypanosoma brucei DNA polymerase eta, putative 0.0069 0.0044 0.0175
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0027 0.0007 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0001 0.0001
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0027 0.0007 0.0007
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0198 0.016 0.0636
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0019 0.0075
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.004 0.016
Schistosoma mansoni ap endonuclease 0.0132 0.0101 0.0399
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0003 0.0025
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.0007 0.0058
Brugia malayi beta-lactamase family protein 0.0308 0.0259 0.2326
Loa Loa (eye worm) DEAH box polypeptide 35 0.0035 0.0014 0.0126
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0563 0.0487 0.4377
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0003 0.0011
Echinococcus multilocularis carbonic anhydrase II 0.0198 0.016 0.016
Schistosoma mansoni neuropeptide receptor 0.0021 0.0001 0.0005
Brugia malayi G-protein alpha subunit 0.0021 0.0001 0.0012
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0107 0.0079 0.0709
Echinococcus multilocularis expressed protein 0.0046 0.0024 0.0024
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0021 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0003 0.0025
Plasmodium vivax acyl-CoA synthetase, putative 0.0041 0.002 0.0764
Echinococcus multilocularis follistatin 0.0046 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0012
Echinococcus multilocularis snurportin 1 0.064 0.0556 0.0556
Onchocerca volvulus 0.0308 0.0259 0.5553
Brugia malayi PHD-finger family protein 0.006 0.0036 0.0326
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0001 0.0005
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0007 0.0058
Echinococcus granulosus aldo keto reductase 0.0055 0.0032 0.0127
Brugia malayi Pre-SET motif family protein 0.0473 0.0407 0.3657
Brugia malayi hypothetical protein 0.0021 0.0001 0.0011
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0055 0.0032 0.0289
Echinococcus granulosus ferritin 0.0027 0.0007 0.0027
Schistosoma mansoni ferritin 0.0027 0.0007 0.0027
Onchocerca volvulus 0.0021 0.0001 0.0008
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0091 0.0065 0.0256
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0087 0.0061 0.0241
Schistosoma mansoni hypothetical protein 0.002 0 0.0001
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0003 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0046 0.0182
Entamoeba histolytica hypothetical protein 0.0228 0.0187 0.0736
Mycobacterium ulcerans bacterioferritin BfrA 0.0027 0.0007 0.0127
Echinococcus granulosus dna polymerase kappa 0.004 0.0019 0.0075
Brugia malayi ORL1-like opioid receptor 0.0021 0.0001 0.0011
Plasmodium vivax flavodoxin domain containing protein 0.0021 0.0001 0.0042
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0308 0.0259 0.1026
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0027 0.0007 0.0647
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0019 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0019 0.0075
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0026 0.0103
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0055 0.0032 0.0032
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0027 0.0007 0.0026
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0003 0.0011
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1969 0.1746 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0178 0.0142 0.0142
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0021 0.0001 0.0005
Trichomonas vaginalis aldo-keto reductase, putative 0.0055 0.0032 0.0123
Trypanosoma brucei unspecified product 0.0028 0.0008 0.0031
Mycobacterium ulcerans putative transglutaminase-like protein 0.0071 0.0047 0.1691
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0003 0.0025
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0091 0.0065 0.0065
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0007 0.0252
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0105 0.0077 0.0302
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0021 0.0001 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0032 0.0121
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.0022 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0003 0.0025
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.0054 0.2075
Echinococcus granulosus synaptojanin 1 0.0027 0.0007 0.0026
Mycobacterium tuberculosis Hypothetical protein 0.0071 0.0047 0.0231
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0041 0.002 0.0178
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0027 0.0007 0.0026
Mycobacterium tuberculosis Probable reductase 0.011 0.0082 0.0431
Brugia malayi jmjC domain containing protein 0.0196 0.0158 0.1421
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0027 0.0007 0.0026
Echinococcus granulosus lysine specific demethylase 5A 0.0078 0.0052 0.0208
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.0032 0.0121
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0019 0.0071
Schistosoma mansoni hypothetical protein 0.006 0.0036 0.0144
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0308 0.0259 0.2326
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0045 0.0177
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0308 0.0259 0.1026
Brugia malayi hypothetical protein 0.0021 0.0001 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0308 0.0259 0.1022
Schistosoma mansoni hypothetical protein 0.0021 0.0001 0.0005
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0055 0.0032 0.0127
Mycobacterium ulcerans hypothetical protein 0.0055 0.0032 0.1122
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0039 0.0018 0.0071
Echinococcus multilocularis sex peptide receptor 0.0021 0.0001 0.0001
Brugia malayi Intermediate filament tail domain containing protein 0.019 0.0153 0.1371
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0023 0.0003 0.0133
Loa Loa (eye worm) hypothetical protein 0.0039 0.0018 0.0161
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0003 0.0003
Schistosoma mansoni bromodomain containing protein 0.0075 0.005 0.0197
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0019 0.0075
Trichomonas vaginalis sucrase-isomaltase, putative 0.0105 0.0077 0.0302
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0023 0.009
Mycobacterium ulcerans esterase/lipase LipP 0.0308 0.0259 1
Schistosoma mansoni neutral sphingomyelinase 0.0027 0.0007 0.0026
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0001 0.0005
Brugia malayi Bromodomain containing protein 0.0066 0.0042 0.0376
Schistosoma mansoni hypothetical protein 0.2302 0.2045 0.8111
Onchocerca volvulus 0.0021 0.0001 0.0008
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0089 0.0351
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0007 0.0026
Brugia malayi TAR-binding protein 0.0135 0.0104 0.0931
Brugia malayi AMP-binding enzyme family protein 0.0055 0.0032 0.029
Onchocerca volvulus 0.0275 0.0229 0.4912
Mycobacterium tuberculosis Probable lipase LipE 0.0308 0.0259 0.145
Leishmania major aldo-keto reductase-like protein 0.0055 0.0032 0.0127
Brugia malayi nuclear receptor NHR-88 0.0022 0.0003 0.0025
Echinococcus granulosus carbonic anhydrase II 0.0198 0.016 0.0636
Echinococcus multilocularis expressed protein 0.0021 0.0001 0.0001
Brugia malayi Probable ClpP-like protease 0.0091 0.0065 0.058
Schistosoma mansoni aldehyde dehydrogenase 0.0193 0.0156 0.0618
Trichomonas vaginalis Phospholipase C precursor, putative 0.0027 0.0007 0.0021
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0039 0.0018 0.0065
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0091 0.0065 0.2493
Echinococcus multilocularis lysosomal alpha glucosidase 0.0475 0.0409 0.0409
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0026 0.0026
Leishmania major 4-coumarate:coa ligase-like protein 0.0055 0.0032 0.0128
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0046 0.0024 0.0924
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0003 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0019 0.0075
Echinococcus granulosus neutral alpha glucosidase AB 0.0105 0.0077 0.0306
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0252
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0483 0.0416 0.0416
Brugia malayi ecdysteroid receptor 0.0022 0.0003 0.0025
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.0007 0.0058
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0423 0.0362 0.1435
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Brugia malayi follicle stimulating hormone receptor 0.0275 0.0229 0.2059
Loa Loa (eye worm) hypothetical protein 0.0145 0.0112 0.1009
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.0007 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0003 0.0025
Brugia malayi larval opioid receptor 0.0021 0.0001 0.0011
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0021 0.0001 0.0005
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.006 0.0036 0.0171
Echinococcus multilocularis lamin dm0 0.019 0.0153 0.0153
Entamoeba histolytica Ran family GTPase 0.0044 0.0022 0.0083
Loa Loa (eye worm) hypothetical protein 0.0308 0.0259 0.2326
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0021 0.0001 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0043 0.0387
Echinococcus granulosus Transglutaminase 0.0071 0.0047 0.0185
Echinococcus granulosus survival motor neuron protein 1 0.1261 0.1113 0.4413
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0021 0.0001 0.0005
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0055 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0076 0.0051 0.0454
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0001 0.0005
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0021
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0027 0.0007 0.0026
Onchocerca volvulus 0.0021 0.0001 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0003 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0308 0.0259 0.1026
Schistosoma mansoni inositol monophosphatase 0.0118 0.0089 0.0351
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0193 0.0156 0.0156
Loa Loa (eye worm) acetyltransferase 0.0151 0.0118 0.106
Brugia malayi hypothetical protein 0.0021 0.0001 0.0011
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.0022 0.086
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0021 0.0001 0.0012
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0003 0.0003
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0023 0.0003 0.0014
Onchocerca volvulus 0.0055 0.0032 0.0674
Echinococcus multilocularis dna polymerase eta 0.0069 0.0044 0.0044
Schistosoma mansoni carbon catabolite repressor protein 0.0027 0.0007 0.0026
Brugia malayi Pre-SET motif family protein 0.0069 0.0045 0.04
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0001 0.0005
Brugia malayi glutathione reductase 0.0048 0.0026 0.0234
Brugia malayi Bromodomain containing protein 0.0045 0.0023 0.0204
Brugia malayi sulfakinin receptor protein 0.0021 0.0001 0.0011
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0021 0.0001 0.0005
Schistosoma mansoni ferritin light chain 0.0027 0.0007 0.0027
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0104 0.0411
Brugia malayi cytoplasmic intermediate filament protein 0.0102 0.0074 0.0662
Plasmodium falciparum aldehyde reductase, putative 0.0055 0.0032 0.3192
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Mycobacterium tuberculosis Conserved hypothetical protein 0.0071 0.0047 0.0231
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0003 0.0042
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0021 0.0001 0.0011
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0178 0.0142 0.0564
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0021 0.0001 0.0005
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0132 0.0101 0.0399
Loa Loa (eye worm) hypothetical protein 0.0176 0.014 0.1259
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.0011
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0027 0.0007 0.0021
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0112 0.0444
Echinococcus granulosus dnaJ subfamily B 0.0824 0.0721 0.2859
Schistosoma mansoni amine GPCR 0.0021 0.0001 0.0005
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0007 0.0021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0483 0.0416 0.1648
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0021 0.0001 0.0001
Schistosoma mansoni opsin-like receptor 0.0021 0.0001 0.0005
Mycobacterium ulcerans hypothetical protein 0.0071 0.0047 0.1691
Onchocerca volvulus 0.0021 0.0001 0.0008
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.0022 0.0022
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0055 0.0032 0.0127
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.2834 0.2522 1
Giardia lamblia Transglutaminase/protease, putative 0.0071 0.0047 0.0181
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0001 0.0001
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0058
Trypanosoma brucei aldo-keto reductase, putative 0.0055 0.0032 0.0127
Brugia malayi hypothetical protein 0.0021 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0107 0.0079 0.0709
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0308 0.0259 0.145
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0001 0.0005
Echinococcus granulosus lysosomal alpha glucosidase 0.0475 0.0409 0.162

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 12.8 uM Inhibition of human recombinant PTP1B after 30 mins ChEMBL. 18798681

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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