Detailed information for compound 1017383

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 268.221 | Formula: C15H8O5
  • H donors: 1 H acceptors: 3 LogP: 2.88 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1c2cccc(c2C(=O)c2c1c1OCOc1cc2)O
  • InChi: 1S/C15H8O5/c16-9-3-1-2-7-11(9)13(17)8-4-5-10-15(20-6-19-10)12(8)14(7)18/h1-5,16H,6H2
  • InChiKey: KSOSMCYIAOHPFJ-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Echinococcus multilocularis lamin dm0 0.0083 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0005 0.002
Brugia malayi MH2 domain containing protein 0.0017 0.001 0.0049
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0072 0.0105 0.0105
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.004 0.004
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.003 0.0033 0.2737
Echinococcus granulosus histone acetyltransferase KAT2B 0.0089 0.0134 0.037
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0047 0.0069
Brugia malayi ubiquitin specific protease 14 0.0013 0.0003 0.0015
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0013 0.0003 0.0003
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0 0.0000016323
Schistosoma mansoni steroid hormone receptor ad4bp 0.0072 0.0105 0.029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0015
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0013 0.0003 0.0005
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0077 0.0113 0.0188
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.012 1
Schistosoma mansoni nuclear hormone receptor 0.0034 0.004 0.011
Echinococcus multilocularis flap endonuclease 1 0.0029 0.003 0.003
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0047 0.0069
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0047 0.013
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0013 0.0003 0.0003
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.003 0.0033 0.0321
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.145
Echinococcus multilocularis smad 0.0017 0.001 0.001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.005 0.263
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.003 0.0033 0.0059
Brugia malayi Steroid receptor seven-up type 2 0.0072 0.0105 0.0499
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0013 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0108 0.0167 0.0798
Brugia malayi nuclear receptor NHR-88 0.0034 0.004 0.0189
Loa Loa (eye worm) hypothetical protein 0.0148 0.0235 0.1118
Entamoeba histolytica acetyltransferase, GNAT family 0.0081 0.0121 0.0573
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0013 0.0003 0.0008
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0103 0.0157 0.0268
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0068 0.0097 0.5139
Echinococcus granulosus tumor protein p63 0.1009 0.1711 0.4743
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0023 0.0021 0.0206
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0013 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0103 0.0157 0.1541
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0013 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0072 0.0105 0.0499
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0013 0.0003 0.0218
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0068 0.0097 0.0174
Onchocerca volvulus 0.0207 0.0337 0.5544
Loa Loa (eye worm) hypothetical protein 0.0145 0.0229 0.1093
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.0189 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0106 0.0175
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Schistosoma mansoni patched 1 0.0046 0.006 0.0168
Schistosoma mansoni survival motor neuron protein 0.0252 0.0413 0.1145
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0074 0.6161
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0605 0.1019 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Trypanosoma brucei unspecified product 0.0015 0.0007 0.0507
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0 0.0000016323
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0016 0.0009 0.0683
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Schistosoma mansoni lamin 0.0083 0.0123 0.0342
Onchocerca volvulus 0.0103 0.0157 0.2585
Onchocerca volvulus 0.0083 0.0123 0.2025
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.003 0.0033 0.195
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.005 0.0236
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.3257 0.5567 1
Schistosoma mansoni chromosome transmission fidelity factor 0.0011 0 0.0001
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0008 0.0023
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Giardia lamblia Hypothetical protein 0.0013 0.0003 0.0012
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.003 0.0033 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0015 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.002
Schistosoma mansoni hypothetical protein 0.048 0.0805 0.223
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0043 0.0062
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.005 0.0089
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0014 0.0068
Brugia malayi Smad1 0.0017 0.001 0.0049
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0034 0.004 0.0189
Leishmania major 4-coumarate:coa ligase-like protein 0.0103 0.0157 1
Schistosoma mansoni intermediate filament proteins 0.0083 0.0123 0.0342
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0222
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0013 0.0003 0.0008
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0015 0.0041
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0047 0.022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0556 0.0936 0.4444
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0072 0.0105 0.0499
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0103 0.0157 0.0268
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0476 0.0798 0.3802
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.003 0.0033 0.0059
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.004 0.004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0033 0.0158
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0047 0.3885
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0083 0.0123 0.0588
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0027 0.0028 0.0028
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0013 0.0003 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0072 0.0105 0.0499
Schistosoma mansoni inositol monophosphatase 0.004 0.005 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Echinococcus multilocularis protein dispatched 1 0.0053 0.0072 0.0072
Trichomonas vaginalis flap endonuclease-1, putative 0.0029 0.003 0.0143
Trichomonas vaginalis ubiquitin specific protease, putative 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0072 0.0105 0.029
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.003 0.0033 0.0044
Echinococcus granulosus expressed conserved protein 0.0101 0.0154 0.0428
Giardia lamblia DUB-1 0.0013 0.0003 0.0012
Loa Loa (eye worm) nuclear hormone receptor 0.0034 0.004 0.0189
Brugia malayi hypothetical protein 0.0038 0.0047 0.0222
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0016 0.0009 0.0015
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0072 0.0105 0.0499
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0018 0.145
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0013 0.0003 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0072 0.0105 0.0499
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0226
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0108 0.0167 0.0167
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0013 0.0003 0.0003
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0138
Onchocerca volvulus 0.003 0.0033 0.0538
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Echinococcus granulosus FTZ F1 alpha 0.0072 0.0105 0.029
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.002
Brugia malayi hypothetical protein 0.0013 0.0003 0.0015
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0013 0.0003 0.0218
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0113 0.0113
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0047 0.013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0028 0.0078
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0077 0.0113 0.0202
Plasmodium vivax acyl-CoA synthetase, putative 0.0077 0.0113 0.0202
Brugia malayi AMP-binding enzyme family protein 0.003 0.0033 0.0158
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0005 0.002
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.001 0.0028
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0018 0.0082
Entamoeba histolytica acyl-CoA synthetase, putative 0.0103 0.0157 0.0746
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0058 0.0274
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.003 0.0033 0.0155
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0081 0.012 0.0332
Echinococcus granulosus survival motor neuron protein 1 0.1235 0.2098 0.5816
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0223
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0013 0.0003 0.0008
Plasmodium vivax ubiquitin specific protease, putative 0.0013 0.0003 0.0005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0013 0.0003 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0074 0.0132
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0013 0.0003 0.0003
Toxoplasma gondii ubiquitin-specific protease USP4 0.0013 0.0003 0.0138
Echinococcus granulosus flap endonuclease 1 0.0029 0.003 0.0084
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0016 0.0009 0.0039
Schistosoma mansoni coup transcription factor 0.0072 0.0105 0.029
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0013 0.0003 0.0008
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0047 0.0069
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0113 0.0313
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0106 0.0175
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0015
Loa Loa (eye worm) oxidoreductase 0.003 0.0033 0.0158
Chlamydia trachomatis oxoacyl-ACP synthase III 0.3257 0.5567 1
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0018 0.145
Trichomonas vaginalis glucosylceramidase, putative 0.0556 0.0936 0.4444
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0018 0.0085
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0058 0.0274
Entamoeba histolytica fatty acid elongase, putative 0.0423 0.0707 0.3357
Loa Loa (eye worm) hypothetical protein 0.0072 0.0105 0.0499
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.002
Onchocerca volvulus 0.0027 0.0028 0.0458
Brugia malayi AMP-binding enzyme family protein 0.003 0.0033 0.0158
Echinococcus granulosus smad 0.0017 0.001 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0033 0.0059
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0013 0.0003 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0556 0.0936 0.4459
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.0105 0.029
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0013 0.0003 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0077 0.0113 0.0538
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0013 0.0003 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0556 0.0936 0.4444
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0302 0.0499 0.0499
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0013 0.0003 0.0003
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0068 0.0097 0.0174
Loa Loa (eye worm) intermediate filament protein 0.0083 0.0123 0.0588
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0047 0.022
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0068 0.0097 0.0174
Brugia malayi tailless protein 0.0034 0.004 0.0189
Loa Loa (eye worm) hypothetical protein 0.0103 0.0157 0.075
Echinococcus granulosus dna polymerase eta 0.0021 0.0018 0.0049
Brugia malayi acetyl-Coenzyme A synthetase 2 0.003 0.0033 0.0158
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.3257 0.5567 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.002
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0038 0.0047 0.0222
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0107 0.0166 0.0789
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0013 0.0003 0.0003
Onchocerca volvulus 0.0034 0.004 0.0646
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.003 0.0033 0.0044
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0003 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0013 0.0003 0.0008
Entamoeba histolytica hypothetical protein 0.0077 0.0113 0.0535
Entamoeba histolytica fatty acid elongase, putative 0.0423 0.0707 0.3357
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0011 0 0.0002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.005 0.4152
Brugia malayi orphan nuclear receptor NR2E1 0.0034 0.004 0.0189
Onchocerca volvulus 0.0072 0.0105 0.1719
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0013 0.0003 0.0008
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Brugia malayi nuclear hormone receptor 0.0072 0.0105 0.0499
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0013 0.0003 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Onchocerca volvulus 0.0013 0.0003 0.0043
Echinococcus multilocularis musashi 0.0083 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Giardia lamblia Histone acetyltransferase GCN5 0.0081 0.0121 0.0573
Toxoplasma gondii ABC1 family protein 0.0038 0.0047 0.2461
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0013 0.0003 0.0012
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0013 0.0003 0.0008
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0013 0.0003 0.0138
Onchocerca volvulus 0.0059 0.0083 0.1367
Brugia malayi ecdysteroid receptor 0.0072 0.0105 0.0499
Brugia malayi hypothetical protein 0.0054 0.0074 0.0353
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0029 0.003 0.1591
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0106 0.0175
Schistosoma mansoni smad 0.0017 0.001 0.0028
Brugia malayi Nuclear hormone receptor E75 0.0034 0.004 0.0189
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0013 0.0003 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0047 0.022
Brugia malayi Niemann-Pick C1 protein precursor 0.0107 0.0166 0.0789
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Schistosoma mansoni cellular tumor antigen P53 0.0148 0.0235 0.065
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0015
Schistosoma mansoni zinc finger protein 0.0034 0.004 0.011
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0027 0.0028 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0033 0.0059
Brugia malayi Intermediate filament tail domain containing protein 0.0083 0.0123 0.0588
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0229 0.0229
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0072 0.0105 0.029
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0047 0.0069
Entamoeba histolytica hypothetical protein 0.0077 0.0113 0.0535
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0072 0.0105 0.029
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.005 0.0089
Plasmodium vivax flap endonuclease 1, putative 0.0029 0.003 0.0054
Echinococcus granulosus muscleblind protein 0.0145 0.0229 0.0636
Brugia malayi nuclear receptor NHR-88 0.0072 0.0105 0.0499
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.145
Echinococcus granulosus dnaJ subfamily B 0.0847 0.1434 0.3974
Schistosoma mansoni nuclear receptor nhr-48 0.0034 0.004 0.011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0222
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0138
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Echinococcus multilocularis cpg binding protein 0.0063 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0133 0.0209 0.0995
Brugia malayi steroid hormone receptor 0.0072 0.0105 0.0499
Loa Loa (eye worm) hypothetical protein 0.0072 0.0105 0.0499
Echinococcus multilocularis lamin 0.0083 0.0123 0.0123
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Echinococcus granulosus Smad4 0.0017 0.001 0.0028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1238 0.2105 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0018 0.0085
Mycobacterium tuberculosis Conserved protein 0.0038 0.0047 0.0069
Treponema pallidum exodeoxyribonuclease (exoA) 0.0016 0.0009 0.0039
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0018 0.145
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0013 0.0003 0.0008
Onchocerca volvulus 0.0252 0.0413 0.68
Echinococcus granulosus ecdysone induced protein 78C 0.0072 0.0105 0.029
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.002
Brugia malayi MH2 domain containing protein 0.0246 0.0404 0.1924
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0013 0.0003 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.003 0.0033 0.0092
Brugia malayi CXXC zinc finger family protein 0.0059 0.0083 0.0398
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.3257 0.5567 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.004 0.011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.0303 0.084
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0025 0.0024 0.0068
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0047 0.0222
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Brugia malayi beta-lactamase 0.0038 0.0047 0.0223
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.003 0.0033 0.2737
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Schistosoma mansoni topbp1 0.0011 0 0.0001
Trichomonas vaginalis esterase, putative 0.0038 0.0047 0.022
Echinococcus granulosus inositol monophosphatase 1 0.004 0.005 0.0139
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.0303 0.084
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.001 0.0049
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0138
Mycobacterium ulcerans lipase LipD 0.0038 0.0047 0.0083
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0013 0.0003 0.0003
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0047 0.0456
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0026 0.0031
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0108 0.0167 0.0798
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0365 0.0608 0.2885
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0013 0.0003 0.0012
Toxoplasma gondii propionate-CoA ligase 0.003 0.0033 0.1734
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0013 0.0003 0.0003
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0081 0.012 0.0332
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.0399 0.0702
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.004 0.004
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0038 0.0047 0.0129
Entamoeba histolytica hypothetical protein 0.0077 0.0113 0.0535
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Echinococcus multilocularis thyroid hormone receptor alpha 0.0072 0.0105 0.0105
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.0303 0.084
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Mycobacterium ulcerans acyl-CoA synthetase 0.0103 0.0157 0.0282
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0103 0.0157 0.1541
Schistosoma mansoni DNA polymerase eta 0.0021 0.0018 0.0049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.3257 0.5567 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0223
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0047 0.0129
Trichomonas vaginalis set domain proteins, putative 0.0207 0.0337 0.16
Mycobacterium ulcerans beta-lactamase 0.0038 0.0047 0.0083
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0081 0.012 0.012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0013 0.0003 0.0008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0188 0.0303 0.1445
Echinococcus granulosus thyroid hormone receptor alpha 0.0034 0.004 0.011
Loa Loa (eye worm) hypothetical protein 0.0081 0.012 0.0571
Schistosoma mansoni retinoic acid receptor RXR 0.0072 0.0105 0.029
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0013 0.0003 0.0138
Echinococcus granulosus neuropeptide s receptor 0.0505 0.0848 0.235
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.003 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0077 0.0113 0.0313
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0138
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0018 0.0031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.1235 0.2098 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0302 0.0499 0.1383
Loa Loa (eye worm) hypothetical protein 0.0103 0.0157 0.075
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Leishmania major hypothetical protein, conserved 0.0054 0.0074 0.4599
Loa Loa (eye worm) MH2 domain-containing protein 0.0246 0.0404 0.1924
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.002
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0034 0.004 0.0189
Echinococcus multilocularis protein patched 0.0046 0.006 0.006
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0016 0.0009 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.004 0.0646
Brugia malayi latrophilin 2 splice variant baaae 0.0234 0.0383 0.1826
Trichomonas vaginalis glucosylceramidase, putative 0.0385 0.0641 0.3045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Brugia malayi ecdysone receptor 0.0034 0.004 0.0189
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.005 0.0236
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0072 0.0105 0.0499
Brugia malayi hypothetical protein 0.0133 0.0209 0.0995
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0103 0.0157 0.075
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0081 0.012 0.0332
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0033 0.0044
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Schistosoma mansoni hypothetical protein 0.0024 0.0023 0.0064
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0068 0.0097 0.027
Brugia malayi hypothetical protein 0.0011 0 0.0002
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Echinococcus granulosus intermediate filament protein 0.0083 0.0123 0.0342
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Brugia malayi Flap endonuclease-1 0.0029 0.003 0.0145
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0605 0.1019 0.1829
Echinococcus granulosus Protein patched homolog 1 0.0046 0.006 0.0168
Echinococcus multilocularis peptidase Clp (S14 family) 0.0044 0.0057 0.0057
Onchocerca volvulus Bile acid receptor homolog 0.0072 0.0105 0.1719
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.005 0.005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0008 0.0023
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0242 0.0396 0.1098
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0016 0.0009 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Brugia malayi MH1 domain containing protein 0.0017 0.001 0.0049
Schistosoma mansoni cpg binding protein 0.0063 0.0089 0.0247
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma brucei acetyl-CoA synthetase, putative 0.003 0.0033 0.2737
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0033 0.0059
Schistosoma mansoni hypothetical protein 0.0044 0.0058 0.016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0072 0.0105 0.029
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0018 0.145
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus granulosus sterol regulatory element binding protein 0.0046 0.006 0.0168
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.003 0.0033 0.0321
Treponema pallidum fructose-bisphosphate aldolase 0.1238 0.2105 1
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0011 0 0.0000016323
Trichomonas vaginalis glucosylceramidase, putative 0.0365 0.0608 0.2885
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0072 0.0105 0.0499
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0023 0.0021 0.01
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0028 0.0078
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1238 0.2105 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Mycobacterium ulcerans acetyl-CoA synthetase 0.003 0.0033 0.0059
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0013 0.0003 0.0003
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.005 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.0365 0.0608 0.2885
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0044 0.0057 0.0088
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0005
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0013 0.0003 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0016 0.0009 0.0015
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0047 0.0083
Onchocerca volvulus 0.0038 0.0047 0.0764
Schistosoma mansoni Smad4 0.0017 0.001 0.0028
Echinococcus multilocularis muscleblind protein 0.0145 0.0229 0.0229
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0016 0.0009 0.0683
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0109 0.0168 0.0467
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0018 0.0049
Echinococcus multilocularis geminin 0.048 0.0805 0.0805
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.003 0.0033 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.012 0.0568
Loa Loa (eye worm) hypothetical protein 0.0234 0.0383 0.1826
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.004 0.011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0223
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.003 0.0033 0.2737
Brugia malayi beta-lactamase family protein 0.0038 0.0047 0.0223
Brugia malayi nuclear receptor NHR-67 0.0034 0.004 0.0189
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.005 0.4152
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0046 0.006 0.0288
Giardia lamblia DINP protein human, muc B family 0.0021 0.0018 0.0082
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1238 0.2105 1
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0013 0.0003 0.0008
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0018 0.0082
Schistosoma mansoni peptidase 0.0013 0.0003 0.0008
Echinococcus granulosus neuropeptide receptor A26 0.0505 0.0848 0.235
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.005 0.0139
Trichomonas vaginalis glucosylceramidase, putative 0.0365 0.0608 0.2885
Schistosoma mansoni calpain-7 (C02 family) 0.0013 0.0003 0.0008
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0013 0.0003 0.0005
Giardia lamblia Flap structure-specific endonuclease 0.0029 0.003 0.0143
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0016 0.0009 0.0024
Leishmania major acetyl-CoA synthetase, putative 0.003 0.0033 0.195
Brugia malayi MH2 domain containing protein 0.0017 0.001 0.0049
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0138
Mycobacterium leprae Probable lipase LipE 0.0038 0.0047 0.0456
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0013 0.0003 0.0005
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0047 0.3885
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0013 0.0003 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0033 0.0059
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0013 0.0003 0.0008
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0013 0.0003 0.0003
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Echinococcus granulosus nibrin 0.0011 0 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1238 0.2105 1
Schistosoma mansoni smad1 5 8 and 0.0017 0.001 0.0028
Brugia malayi hypothetical protein 0.0035 0.0041 0.0197
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0034 0.004 0.004
Brugia malayi Probable ClpP-like protease 0.0068 0.0097 0.0464
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0365 0.0608 0.2885
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0013 0.0003 0.0008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0009 0.0683
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0033 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0106 0.0175
Schistosoma mansoni hypothetical protein 0.0013 0.0003 0.0008
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0047 0.0047
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0072 0.0105 0.0499
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0018 0.145
Brugia malayi MH1 domain containing protein 0.0017 0.001 0.0049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1238 0.2105 1
Leishmania major hypothetical protein, conserved 0.0038 0.0047 0.2838
Loa Loa (eye worm) latrophilin receptor protein 2 0.0108 0.0167 0.0798
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.003 0.0033 0.0059
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0013 0.0003 0.0003
Plasmodium falciparum ubiquitin specific protease, putative 0.0013 0.0003 0.0005
Schistosoma mansoni ap endonuclease 0.0016 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1238 0.2105 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0043 0.0416
Loa Loa (eye worm) nuclear receptor NHR-67 0.0034 0.004 0.0189
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0013 0.0003 0.0008
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0013 0.0003 0.0015
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0077 0.0113 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0047 0.3885
Entamoeba histolytica Flap nuclease, putative 0.0029 0.003 0.0143
Schistosoma mansoni peptidase Clp (S14 family) 0.0068 0.0097 0.027
Loa Loa (eye worm) flap endonuclease-1 0.0029 0.003 0.0145
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0081 0.012 0.0571
Trypanosoma brucei unspecified product 0.0015 0.0007 0.0507
Brugia malayi hypothetical protein 0.0038 0.0047 0.0222
Echinococcus granulosus replication factor c subunit 1 0.0011 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0077 0.0113 0.0538
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0223
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0013 0.0003 0.0012
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0072 0.0105 0.029
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0222
Schistosoma mansoni flap endonuclease-1 0.0026 0.0026 0.0071
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Brugia malayi Nuclear hormone receptor E75 0.0034 0.004 0.0189
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0108 0.0167 0.0464
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0018 0.0085
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0033 0.0059
Loa Loa (eye worm) hypothetical protein 0.0054 0.0074 0.0353
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus multilocularis tumor protein p63 0.1009 0.1711 0.1711
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0072 0.0105 0.0499
Loa Loa (eye worm) hypothetical protein 0.0072 0.0105 0.0499
Brugia malayi Muscleblind-like protein 0.0145 0.0229 0.1093
Brugia malayi photoreceptor-specific nuclear receptor 0.0072 0.0105 0.0499
Schistosoma mansoni hypothetical protein 0.0108 0.0167 0.0464
Brugia malayi follicle stimulating hormone receptor 0.0706 0.1192 0.5682
Echinococcus granulosus GPCR family 2 0.0108 0.0167 0.0464
Schistosoma mansoni lamin 0.0083 0.0123 0.0342
Trichomonas vaginalis glucosylceramidase, putative 0.0365 0.0608 0.2885
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.005 0.4152
Mycobacterium ulcerans hypothetical protein 0.0038 0.0047 0.0083
Brugia malayi nuclear hormone receptor family member odr-7 0.0034 0.004 0.0189
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Toxoplasma gondii hypothetical protein 0.0023 0.0021 0.1112
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0027 0.0028 0.1474
Onchocerca volvulus 0.0034 0.004 0.0653
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0018 0.145
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.001 0.001
Brugia malayi nuclear receptor RXR 0.0034 0.004 0.0189
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0072 0.0105 0.0499
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0016 0.0009 0.0041
Mycobacterium tuberculosis Conserved protein 0.0038 0.0047 0.0069
Schistosoma mansoni hypothetical protein 0.0847 0.1434 0.3974
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0008 0.0008
Brugia malayi hypothetical protein 0.0034 0.004 0.0189
Trichomonas vaginalis bromodomain-containing protein, putative 0.0089 0.0134 0.0633
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0013 0.0003 0.0008
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0072 0.0105 0.029
Schistosoma mansoni nuclear receptor 0.0034 0.004 0.011
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0103 0.0157 0.0282
Plasmodium falciparum ubiquitin specific protease, putative 0.0013 0.0003 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus granulosus dna polymerase kappa 0.0021 0.0018 0.0049
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0013 0.0003 0.0218
Schistosoma mansoni nuclear hormone receptor 0.0072 0.0105 0.029
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0083 0.0398
Brugia malayi Pre-SET motif family protein 0.0182 0.0294 0.1402
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0605 0.1019 0.1817
Brugia malayi Inositol-1 0.004 0.005 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0074 0.0132
Brugia malayi AMP-binding enzyme family protein 0.003 0.0033 0.0158
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0047 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1238 0.2105 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.004 0.011
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Schistosoma mansoni nuclear receptor 0.0034 0.004 0.011
Plasmodium falciparum acetyl-CoA synthetase, putative 0.003 0.0033 0.0059
Echinococcus multilocularis expressed conserved protein 0.0101 0.0154 0.0154
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.003 0.0033 0.0059
Schistosoma mansoni smad1 5 8 and 0.0017 0.001 0.0028
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0018 0.145
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0138
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0023 0.0021 0.0038
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0013 0.0003 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0103 0.0157 0.075
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0008 0.0023
Onchocerca volvulus 0.003 0.0033 0.0538
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Schistosoma mansoni hypothetical protein 0.0044 0.0058 0.016
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0013 0.0003 0.0005
Echinococcus granulosus geminin 0.048 0.0805 0.223
Schistosoma mansoni smad1 5 8 and 0.0017 0.001 0.0028
Echinococcus multilocularis sterol regulatory element binding protein 0.0046 0.006 0.006
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.003 0.0033 0.0044
Schistosoma mansoni microtubule-associated protein tau 0.2115 0.3608 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0013 0.0003 0.0003
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.001 0.001
Brugia malayi Pax transcription activation domain interacting protein 0.0011 0 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0047 0.022
Entamoeba histolytica fatty acid elongase, putative 0.0423 0.0707 0.3357
Schistosoma mansoni topbp1 0.0011 0 0.0001
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Brugia malayi Nuclear hormone receptor-like 1 0.0072 0.0105 0.0499
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.002
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0013 0.0003 0.0008
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0074 0.6161
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0016 0.0009 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.0303 0.0303
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0068 0.0097 0.0952
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0023 0.0023
Echinococcus granulosus Niemann Pick C1 protein 0.0107 0.0166 0.0459
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.145
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Schistosoma mansoni hypothetical protein 0.0044 0.0058 0.016
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0072 0.0105 0.0499
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.005 0.0236
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0068 0.0097 0.0461
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0013 0.0003 0.0008
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.003 0.0033 0.0321
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0029 0.003 0.2511
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0029 0.003 0.1775
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0103 0.0157 0.0282
Echinococcus granulosus histone lysine methyltransferase setb 0.0027 0.0028 0.0078
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Schistosoma mansoni ap endonuclease 0.0016 0.0009 0.0024
Trichomonas vaginalis ap endonuclease, putative 0.0016 0.0009 0.0039
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0068 0.0097 0.0174
Brugia malayi hypothetical protein 0.0011 0 0.0002
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0013 0.0003 0.0008
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0013 0.0003 0.0005
Brugia malayi Latrophilin receptor protein 2 0.0108 0.0167 0.0798
Loa Loa (eye worm) hypothetical protein 0.0145 0.0229 0.1093
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Echinococcus multilocularis neuropeptide s receptor 0.0505 0.0848 0.0848
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0033 0.0059
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0476 0.0798 0.3802
Schistosoma mansoni hypothetical protein 0.0044 0.0058 0.016
Onchocerca volvulus 0.0013 0.0003 0.0043
Echinococcus multilocularis Niemann Pick C1 protein 0.0153 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Echinococcus multilocularis dnaJ subfamily B 0.0847 0.1434 0.1434
Brugia malayi DKFZp564C0469 protein 0.0011 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0135
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0013 0.0003 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.012 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.145
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0081 0.012 0.7569
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0072 0.0105 0.029
Brugia malayi nuclear hormone receptor 0.0034 0.004 0.0189
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0089 0.0134 0.7065
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0012
Schistosoma mansoni hypothetical protein 0.0108 0.0167 0.0464
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0013 0.0003 0.0003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Entamoeba histolytica fatty acid elongase, putative 0.0423 0.0707 0.3357
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0034 0.004 0.004
Echinococcus granulosus ubiquitin specific protease 41 0.0081 0.012 0.0332
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0103 0.0157 0.0282
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0013 0.0003 0.0218
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0072 0.0105 0.0105
Brugia malayi exodeoxyribonuclease III family protein 0.0016 0.0009 0.0041
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0016 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0158
Onchocerca volvulus 0.003 0.0033 0.0538
Loa Loa (eye worm) hypothetical protein 0.0072 0.0105 0.0499
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.002
Trypanosoma brucei unspecified product 0.0021 0.0018 0.145
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.0105 0.029
Loa Loa (eye worm) hypothetical protein 0.0077 0.0113 0.0538
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0072 0.0105 0.0499
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0044 0.0057 0.056
Trichomonas vaginalis ubiquitin specific protease, putative 0.0013 0.0003 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.0303 0.084
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Leishmania major 4-coumarate:coa ligase-like protein 0.0103 0.0157 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Onchocerca volvulus 0.0034 0.004 0.0646
Entamoeba histolytica acyl-coA synthetase, putative 0.0103 0.0157 0.0746
Schistosoma mansoni cpg binding protein 0.0059 0.0083 0.0231
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0188 0.0303 0.1445
Brugia malayi CHE-14 protein 0.0046 0.006 0.0288
Plasmodium vivax SET domain protein, putative 0.0027 0.0028 0.005
Echinococcus granulosus peptidase Clp S14 family 0.0044 0.0057 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0072 0.0105 0.0499
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0068 0.0097 0.0174
Leishmania major DNA polymerase eta, putative 0.0021 0.0018 0.0954
Toxoplasma gondii hypothetical protein 0.0013 0.0003 0.0138
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0033 0.0059
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.005 0.0236
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Entamoeba histolytica fatty acid elongase, putative 0.0423 0.0707 0.3357
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0223
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0013 0.0003 0.0005
Schistosoma mansoni nuclear hormone receptor 0.0034 0.004 0.011
Brugia malayi AMP-binding enzyme family protein 0.003 0.0033 0.0158
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.001 0.0028
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0222
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis replication factor C large subunit, putative 0.0011 0 0.0000016323
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0002
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Echinococcus granulosus ubiquitin specific peptidase c family 0.0013 0.0003 0.0008
Loa Loa (eye worm) AMP-binding enzyme family protein 0.003 0.0033 0.0158
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.001 0.0028
Leishmania major 4-coumarate:coa ligase-like protein 0.0103 0.0157 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0081 0.012 0.012
Schistosoma mansoni RAR-like nuclear receptor 0.0072 0.0105 0.029
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0072 0.0105 0.029
Loa Loa (eye worm) hypothetical protein 0.0103 0.0157 0.075
Brugia malayi hypothetical protein 0.1235 0.2098 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Loa Loa (eye worm) inositol-1 0.004 0.005 0.0238
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0018 0.0018
Schistosoma mansoni cpg binding protein 0.0063 0.0089 0.0247
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0556 0.0936 0.4459
Brugia malayi topoisomerase 0.0011 0 0.0002
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0018 0.0018
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0013 0.0003 0.0003
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1238 0.2105 1
Onchocerca volvulus 0.0038 0.0047 0.0764
Echinococcus multilocularis ecdysone induced protein 78C 0.0072 0.0105 0.0105
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0706 0.1192 0.5682
Brugia malayi hypothetical protein 0.0034 0.004 0.0189
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0013 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.003 0.0033 0.1734
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0085
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0034 0.004 0.011
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0034 0.004 0.011
Echinococcus multilocularis survival motor neuron protein 1 0.1235 0.2098 0.2098
Echinococcus granulosus lamin dm0 0.0083 0.0123 0.0342
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0047 0.0069
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0343 0.0569 0.2712
Echinococcus multilocularis GPCR, family 2 0.0108 0.0167 0.0167
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0018 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Trichomonas vaginalis ubiquitin specific protease, putative 0.0013 0.0003 0.0012
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0038 0.0047 0.0047
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0074 0.3902
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0138
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.0012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0018 0.145
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.0105 0.0105
Onchocerca volvulus Huntingtin homolog 0.0133 0.0209 0.3432
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.145
Onchocerca volvulus 0.0148 0.0235 0.3858
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0068 0.0097 0.0174
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0072 0.0105 0.0499
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.003 0.0033 0.0044
Brugia malayi beta-lactamase family protein 0.0038 0.0047 0.0223
Trichomonas vaginalis antibiotic synthetase, putative 0.003 0.0033 0.0155
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0072 0.0105 0.0499
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0081 0.012 0.0568
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.3257 0.5567 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.0105 0.0105
Trichomonas vaginalis ap endonuclease, putative 0.0016 0.0009 0.0039
Echinococcus multilocularis Niemann Pick C1 protein 0.0107 0.0166 0.0166
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0008 0.0008
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0068 0.0097 0.5139
Schistosoma mansoni hypothetical protein 0.048 0.0805 0.223
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0138
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.3257 0.5567 1
Brugia malayi acetyltransferase, GNAT family protein 0.0302 0.0499 0.2377
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.012 1
Onchocerca volvulus 0.0083 0.0123 0.2025
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0007 0.0507
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1238 0.2105 1
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0013 0.0003 0.0008
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0013 0.0003 0.0138
Trichomonas vaginalis helicase, putative 0.0013 0.0005 0.002
Onchocerca volvulus 0.0038 0.0047 0.0764
Echinococcus multilocularis microtubule associated protein 2 0.2115 0.3608 0.3608
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0103 0.0157 0.0282
Loa Loa (eye worm) acetyltransferase 0.0302 0.0499 0.2377
Echinococcus granulosus nuclear receptor nhr 48 0.0034 0.004 0.011
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0103 0.0157 0.0282
Mycobacterium ulcerans hypothetical protein 0.0103 0.0157 0.0282
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0226
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.0303 0.084
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0013 0.0003 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0385 0.0641 0.3045
Schistosoma mansoni hypothetical protein 0.0108 0.0167 0.0464
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0016 0.0009 0.036
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0027 0.0028 0.0078
Entamoeba histolytica hypothetical protein 0.0077 0.0113 0.0535
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0047 0.022
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0089 0.0134 0.0633
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0089 0.0134 0.0239
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus granulosus lamin 0.0083 0.0123 0.0342
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0072 0.0105 0.0499
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0072 0.0105 0.0499
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0023 0.0021 0.0038
Schistosoma mansoni hypothetical protein 0.0234 0.0383 0.1062
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0068 0.0097 0.0174
Brugia malayi hypothetical protein 0.0077 0.0113 0.0538
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0038 0.0047 0.0129
Trichomonas vaginalis glucosylceramidase, putative 0.0556 0.0936 0.4444
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0138
Trichomonas vaginalis glucosylceramidase, putative 0.0365 0.0608 0.2885
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0072 0.0105 0.029
Schistosoma mansoni DNA ligase IV 0.0011 0 0.0001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0013 0.0003 0.0008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0072 0.0105 0.029
Loa Loa (eye worm) transcription factor SMAD2 0.0246 0.0404 0.1924
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Plasmodium falciparum flap endonuclease 1 0.0029 0.003 0.0054
Schistosoma mansoni thyroid hormone receptor 0.0072 0.0105 0.029
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0033 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0068 0.0097 0.0464
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.145
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0044 0.0057 0.0088
Echinococcus granulosus cpg binding protein 0.0063 0.0089 0.0247
Loa Loa (eye worm) DR-78 0.0034 0.004 0.0189
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0068 0.0097 0.0097
Loa Loa (eye worm) steroid hormone receptor 0.0072 0.0105 0.0499
Echinococcus granulosus histone acetyltransferase KAT2B 0.0293 0.0484 0.1342
Loa Loa (eye worm) hypothetical protein 0.004 0.005 0.0238
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0015 0.0015
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0015
Entamoeba histolytica acyl-CoA synthetase, putative 0.0103 0.0157 0.0746
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0018 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0072 0.0105 0.0499
Echinococcus multilocularis neuropeptide receptor A26 0.0505 0.0848 0.0848
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.012 0.0568
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.145
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.145
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0072 0.0105 0.029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0072 0.0105 0.0499
Leishmania major DNA polymerase kappa, putative 0.0021 0.0018 0.0954
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.145
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0107 0.0166 0.0785
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Brugia malayi conserved hypotetical protein 0.0034 0.004 0.0189
Giardia lamblia Fructose-bisphosphate aldolase 0.1238 0.2105 1
Schistosoma mansoni inositol monophosphatase 0.004 0.005 0.0139
Brugia malayi nuclear hormone receptor family member nhr-6 0.0034 0.004 0.0189
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0133 0.0209 0.0995
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus multilocularis Smad4 0.0017 0.001 0.001
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.001 0.0049
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0074 0.0132
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.003 0.0033 0.2737
Plasmodium vivax acetyl-CoA synthetase, putative 0.003 0.0033 0.0059
Loa Loa (eye worm) hypothetical protein 0.0083 0.0123 0.0588
Echinococcus multilocularis ubiquitin specific protease 41 0.0081 0.012 0.012
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0005
Mycobacterium tuberculosis Conserved protein 0.0038 0.0047 0.0069
Brugia malayi Pre-SET motif family protein 0.0027 0.0028 0.0135
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.003 0.0033 0.0059
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0013 0.0003 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.145
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0072 0.0105 0.0105
Brugia malayi Calcitonin receptor-like protein seb-1 0.0343 0.0569 0.2712
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.003 0.0033 0.0044
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0074 0.6161
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.003 0.0033 0.1734
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.0081 0.0121 0.0576
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.003 0.0033 0.0059
Echinococcus multilocularis dna polymerase eta 0.0021 0.0018 0.0018
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0013 0.0003 0.0008
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0034 0.004 0.011
Echinococcus multilocularis expressed protein 0.0013 0.0003 0.0003
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0013 0.0003 0.0015
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0556 0.0936 0.4444
Loa Loa (eye worm) hypothetical protein 0.0077 0.0113 0.0538
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0034 0.004 0.0189
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0056 0.0078 0.0373
Onchocerca volvulus Huntingtin homolog 0.0133 0.0209 0.3432
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0003 0.0012
Loa Loa (eye worm) AMP-binding enzyme family protein 0.003 0.0033 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0072 0.0105 0.0499
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0047 0.0223
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0018 0.0049
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0018 0.0954
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0013 0.0003 0.0008
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0072 0.0105 0.1719
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.006 0.0285
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0013 0.0003 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0072 0.0105 0.0499
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0013 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0002
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0013 0.0003 0.0015
Schistosoma mansoni thyroid hormone receptor 0.0072 0.0105 0.029
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0158
Toxoplasma gondii exonuclease III APE 0.0016 0.0009 0.0432
Brugia malayi AMP-binding enzyme family protein 0.0103 0.0157 0.075
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0047 0.0069
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0013 0.0003 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0047 0.0223
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0013 0.0003 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.012 0.0568
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1238 0.2105 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0103 0.0157 0.0282
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus granulosus Niemann Pick C1 protein 0.0153 0.0245 0.0678
Loa Loa (eye worm) beta-lactamase 0.0038 0.0047 0.0223
Echinococcus multilocularis nuclear receptor nhr 48 0.0034 0.004 0.004
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0013 0.0003 0.0008
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0018 0.0031
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0089 0.0134 0.7065
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0013 0.0003 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0018 0.145
Trichomonas vaginalis glucosylceramidase, putative 0.0556 0.0936 0.4444
Brugia malayi nuclear receptor RXR 0.0038 0.0047 0.0222
Schistosoma mansoni acetyl-CoA synthetase 0.003 0.0033 0.0092
Echinococcus granulosus microtubule associated protein 2 0.2115 0.3608 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0047 0.0083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0003 0.0015
Schistosoma mansoni calpain-7 (C02 family) 0.0013 0.0003 0.0008
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.003 0.0033 0.0059
Plasmodium falciparum histone acetyltransferase GCN5 0.0081 0.0121 0.0217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0072 0.0105 0.0499
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0072 0.0105 0.0105
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0013 0.0003 0.0003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0018 0.0016
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0081 0.012 0.0567
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0018 0.0049
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0242 0.0396 0.0396
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0003 0.0218
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0222
Loa Loa (eye worm) hypothetical protein 0.0072 0.0105 0.0499
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0013 0.0003 0.0012
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0113 0.0313
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0029 0.003 0.2511
Plasmodium falciparum acyl-CoA synthetase 0.0077 0.0113 0.0202
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0033 0.0059
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0182 0.0294 0.1402
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0023 0.0064
Brugia malayi intermediate filament protein 0.0083 0.0123 0.0588
Loa Loa (eye worm) hypothetical protein 0.0072 0.0105 0.0499
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0252 0.0413 0.197
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.004 0.0646
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0047 0.0083
Schistosoma mansoni hypothetical protein 0.0108 0.0167 0.0464
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0002
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.3257 0.5567 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0047 0.0223
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0007 0.0507
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0028 0.0078
Leishmania major acetyl-CoA synthetase, putative 0.003 0.0033 0.195
Schistosoma mansoni hypothetical protein 0.0252 0.0413 0.1145
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0013 0.0003 0.0003
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.005 0.3045
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0012
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.003 0.0033 0.0059
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0013 0.0003 0.0008
Onchocerca volvulus Protein ultraspiracle homolog 0.0072 0.0105 0.1719
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0047 0.0222
Loa Loa (eye worm) hypothetical protein 0.0077 0.0113 0.0538
Onchocerca volvulus 0.0013 0.0003 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0033 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0007 0.0507
Loa Loa (eye worm) hypothetical protein 0.0046 0.006 0.0288
Trichomonas vaginalis antibiotic synthetase, putative 0.003 0.0033 0.0155
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.0003 0.0218
Echinococcus multilocularis FTZ F1 alpha 0.0072 0.0105 0.0105
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0047 0.013
Onchocerca volvulus Glucosylceramidase homolog 0.0365 0.0608 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0081 0.012 0.0332
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.0003 0.0138
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0003 0.0012
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.003 0.0033 0.2737
Loa Loa (eye worm) Smad1 0.0017 0.001 0.0049
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0199 0.0553

Activities

Activity type Activity value Assay description Source Reference
Activity (ADMET) > 80 % Cytotoxicity against human Raji cells assessed as cell viability at 1000 molar ratio ChEMBL. 2558164
Activity (ADMET) > 80 % Cytotoxicity against human Raji cells assessed as cell viability at 100 molar ratio ChEMBL. 2558164
Activity (ADMET) > 80 % Cytotoxicity against human Raji cells assessed as cell viability at 500 molar ratio ChEMBL. 2558164
Activity (ADMET) > 80 % Cytotoxicity against human Raji cells assessed as cell viability at 10 molar ratio ChEMBL. 2558164

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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