Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1591 | 0.1591 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0053 | 1 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.1591 | 0.5 |
Trypanosoma brucei | protein kinase, putative | 0.0053 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1591 | 0.1591 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0053 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0053 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1591 | 0.1591 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0053 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1591 | 0.1591 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0053 | 1 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0053 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0053 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 1 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0053 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1591 | 0.1591 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1591 | 0.1591 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1591 | 0.1591 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.1591 | 0.1591 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1591 | 0.1591 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.1591 | 0.1591 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.1591 | 0.1591 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.1591 | 0.5 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0053 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0053 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.1591 | 0.1591 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.1591 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0053 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0053 | 1 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0053 | 1 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.1591 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1591 | 0.1591 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.1591 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.1591 | 0.1591 |
Trypanosoma brucei | unspecified product | 0.002 | 0.1591 | 0.1591 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.