TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 433.523 | Formula: C24H23N3O3S
H donors: 3 H acceptors: 2 LogP: 4.31 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: COc1cc(ccc1O)C1CC(=NN1C(=S)Nc1ccccc1C)c1ccccc1O
InChi: 1S/C24H23N3O3S/c1-15-7-3-5-9-18(15)25-24(31)27-20(16-11-12-22(29)23(13-16)30-2)14-19(26-27)17-8-4-6-10-21(17)28/h3-13,20,28-29H,14H2,1-2H3,(H,25,31)
InChiKey: FDPMSDOQKYGNAQ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	voltage dependent L type calcium channel subunit\|voltage dependent calcium channel	0.0055	0.0105	0.0248
Schistosoma mansoni	integrin alpha-ps	0.0035	0.0002	0.0001
Echinococcus multilocularis	transient receptor potential cation channel	0.0055	0.0105	0.0248
Loa Loa (eye worm)	G-protein coupled receptor	0.0137	0.0516	0.0514
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0137	0.0516	0.1239
Echinococcus granulosus	g protein coupled receptor	0.0137	0.0516	0.1239
Brugia malayi	putative neuropeptide receptor NPR1	0.0137	0.0516	0.0514
Brugia malayi	Muscleblind-like protein	0.0152	0.0592	0.0591
Trypanosoma brucei	beta tubulin	0.0161	0.0639	0.9408
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0137	0.0516	0.0765
Echinococcus granulosus	voltage gated potassium channel	0.0055	0.0105	0.0248
Schistosoma mansoni	tubulin subunit beta	0.0161	0.0639	0.0948
Echinococcus granulosus	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Onchocerca volvulus		0.0137	0.0516	0.7208
Loa Loa (eye worm)	voltage-gated potassium channel	0.0055	0.0105	0.0103
Leishmania major	hypothetical protein, conserved	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0137	0.0516	0.1239
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0137	0.0516	0.0765
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Plasmodium vivax	bifunctional dihydrofolate reductase-thymidylate synthase, putative	0.0169	0.0679	1
Echinococcus granulosus	neuropeptides capa receptor	0.0137	0.0516	0.1239
Brugia malayi	Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit	0.0055	0.0105	0.0103
Echinococcus granulosus	tm gpcr rhodopsin	0.0137	0.0516	0.1239
Trypanosoma brucei	DNA polymerase kappa, putative	0.0041	0.0034	0.0494
Trypanosoma brucei	DNA polymerase kappa, putative	0.0041	0.0034	0.0494
Trypanosoma brucei	beta tubulin	0.0161	0.0639	0.9408
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.0055	0.0105	0.0153
Echinococcus multilocularis	two pore calcium channel protein 1	0.0055	0.0105	0.0248
Echinococcus multilocularis	potassium voltage gated channel protein	0.0055	0.0105	0.0248
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0137	0.0516	0.0514
Echinococcus multilocularis	short transient receptor potential channel 6	0.0055	0.0105	0.0248
Loa Loa (eye worm)	endoplasmin	0.0144	0.0553	0.0552
Schistosoma mansoni	voltage-gated ion channel	0.0055	0.0105	0.0153
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Brugia malayi	olfactory channel protein osm-9	0.0055	0.0105	0.0103
Echinococcus multilocularis	somatostatin receptor	0.0137	0.0516	0.1239
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Mycobacterium ulcerans	heat shock protein 90	0.0131	0.0485	0.1408
Echinococcus multilocularis	neuropeptide s receptor	0.0137	0.0516	0.1239
Echinococcus multilocularis	fmrfamide receptor	0.0137	0.0516	0.1239
Echinococcus multilocularis	TRP (transient receptor potential) channel	0.0055	0.0105	0.0248
Echinococcus multilocularis	neuropeptide receptor	0.0285	0.1265	0.3042
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0055	0.0105	0.0153
Trypanosoma cruzi	Heat shock protein 83, putative	0.0144	0.0553	0.8146
Echinococcus granulosus	Tubulin beta 2C chain	0.0161	0.0639	0.1534
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0137	0.0516	0.0514
Onchocerca volvulus		0.0055	0.0105	0.0159
Schistosoma mansoni	endoplasmin	0.0144	0.0553	0.0821
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0648	0.31	0.3099
Echinococcus granulosus	g protein coupled receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0055	0.0105	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Toxoplasma gondii	transporter, cation channel family protein	0.0055	0.0105	0.1523
Onchocerca volvulus	Dipeptidyl peptidase family member 1 homolog	0.0167	0.0671	0.9858
Toxoplasma gondii	heat shock protein 90, putative	0.0144	0.0553	0.8146
Echinococcus granulosus	potassium:sodium hyperpolarization activated	0.0055	0.0105	0.0248
Echinococcus multilocularis	sodium leak channel non selective protein	0.0055	0.0105	0.0248
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0137	0.0516	0.1239
Loa Loa (eye worm)	ion channel NompC	0.0055	0.0105	0.0103
Onchocerca volvulus	Transient receptor potential cation channel trpm homolog	0.0055	0.0105	0.0159
Echinococcus granulosus	potassium voltage gated channel subfamily A	0.0055	0.0105	0.0248
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Brugia malayi	Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit	0.0055	0.0105	0.0103
Echinococcus granulosus	transient receptor potential cation channel	0.0055	0.0105	0.0248
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Echinococcus granulosus	short transient receptor potential channel 6	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0096	0.0094
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Trypanosoma cruzi	inositol 1,4,5-trisphosphate receptor, putative	0.0055	0.0105	0.1523
Echinococcus granulosus	dipeptidyl aminopeptidaseprotein	0.0167	0.0671	0.1611
Schistosoma mansoni	adenoreceptor	0.0137	0.0516	0.0765
Onchocerca volvulus		0.0137	0.0516	0.7208
Brugia malayi	Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog	0.0055	0.0105	0.0103
Brugia malayi	G protein-coupled receptor	0.0137	0.0516	0.0514
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Schistosoma mansoni	hypothetical protein	0.1365	0.6725	1
Trypanosoma cruzi	dihydrofolate reductase-thymidylate synthase	0.0169	0.0679	1
Schistosoma mansoni	endoplasmin	0.0144	0.0553	0.0821
Echinococcus multilocularis	heat shock protein 90	0.0144	0.0553	0.1329
Echinococcus granulosus	potassium voltage gated channel subfamily C	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0058	0.0118	0.0116
Echinococcus multilocularis	voltage gated potassium channel	0.0055	0.0105	0.0248
Trichomonas vaginalis	adenosine deaminase, putative	0.0086	0.0259	0.4047
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Brugia malayi	prolyl oligopeptidase family protein	0.0167	0.0671	0.0669
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Schistosoma mansoni	dipeptidyl-peptidase 9 (S09 family)	0.0056	0.0109	0.016
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0041	0.0034	0.0471
Wolbachia endosymbiont of Brugia malayi	heat shock protein 90	0.0131	0.0485	0.5
Trichomonas vaginalis	tubulin alpha chain, putative	0.0161	0.0639	1
Echinococcus granulosus	potassium voltage gated channel subfamily D	0.0055	0.0105	0.0248
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0137	0.0516	0.0514
Echinococcus multilocularis	sodium channel protein	0.0857	0.4154	1
Toxoplasma gondii	transporter, cation channel family protein	0.0055	0.0105	0.1523
Trypanosoma brucei	Heat shock protein 83, putative	0.0144	0.0553	0.8151
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Brugia malayi	Integrin alpha pat-2 precursor	0.0151	0.0585	0.0584
Trypanosoma brucei	heat shock protein, putative	0.0144	0.0553	0.8151
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0137	0.0516	0.0514
Trypanosoma brucei	DNA polymerase kappa, putative	0.0041	0.0034	0.0494
Echinococcus multilocularis	sex peptide receptor	0.0137	0.0516	0.1239
Echinococcus granulosus	neuropeptide receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	BEN-1 protein	0.0161	0.0639	0.0637
Plasmodium vivax	tubulin beta chain, putative	0.0161	0.0639	0.9041
Brugia malayi	thymidylate synthase	0.0169	0.0679	0.0677
Echinococcus granulosus	hypothetical protein	0.0137	0.0516	0.1239
Brugia malayi	Melatonin receptor type 1A	0.0137	0.0516	0.0514
Echinococcus granulosus	potassium voltage gated channel protein	0.0055	0.0105	0.0248
Mycobacterium leprae	PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE)	0.0169	0.0679	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0137	0.0516	0.1239
Echinococcus granulosus	transient receptor potential cation channel	0.0055	0.0105	0.0248
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0137	0.0516	0.1239
Schistosoma mansoni	subfamily S9B unassigned peptidase (S09 family)	0.0167	0.0671	0.0995
Brugia malayi	G protein-coupled receptor F59B2.13	0.0137	0.0516	0.0514
Echinococcus multilocularis	potassium voltage gated channel subfamily KQT	0.0055	0.0105	0.0248
Brugia malayi	Integrin alpha cytoplasmic region family protein	0.0114	0.04	0.0399
Trypanosoma brucei	Dipeptidyl-peptidase 8-like, putative	0.0056	0.0109	0.1607
Echinococcus multilocularis	muscleblind protein	0.0152	0.0592	0.1423
Schistosoma mansoni	ryanodine receptor related	0.0055	0.0105	0.0153
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus granulosus	beta tubulin	0.0161	0.0639	0.1534
Brugia malayi	Cyclic-nucleotide gated cation channel	0.0055	0.0105	0.0103
Trypanosoma brucei	DNA polymerase kappa, putative	0.0041	0.0034	0.0494
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0137	0.0516	0.0765
Echinococcus multilocularis	potassium voltage gated channel protein	0.0055	0.0105	0.0248
Schistosoma mansoni	biogenic amine receptor	0.0137	0.0516	0.0765
Echinococcus granulosus	biogenic amine 5HT receptor	0.0137	0.0516	0.1239
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0137	0.0516	0.0765
Brugia malayi	Dopamine receptor protein 1	0.0137	0.0516	0.0514
Echinococcus granulosus	short transient receptor potential channel 6	0.0055	0.0105	0.0248
Echinococcus multilocularis	transient receptor potential cation channel	0.0055	0.0105	0.0248
Trypanosoma brucei	heat shock protein 90, putative	0.0144	0.0553	0.8151
Echinococcus granulosus	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Plasmodium falciparum	adenosine deaminase	0.0086	0.0259	0.3806
Schistosoma mansoni	integrin alpha	0.0151	0.0585	0.0868
Onchocerca volvulus		0.0137	0.0516	0.7208
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0091	0.0089
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0054	0.0096	0.0094
Echinococcus granulosus	heat shock protein heat shock protein 90 alpha	0.0131	0.0485	0.1163
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0137	0.0516	0.0765
Echinococcus multilocularis	transient receptor potential cation channel	0.0055	0.0105	0.0248
Loa Loa (eye worm)	prolyl oligopeptidase	0.0167	0.0671	0.0669
Echinococcus granulosus	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Mycobacterium ulcerans	bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase	0.0675	0.3236	1
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Brugia malayi	putative neuropeptide receptor	0.0137	0.0516	0.0514
Echinococcus granulosus	Potassium voltage gated channel protein Shaw	0.0055	0.0105	0.0248
Schistosoma mansoni	hypothetical protein	0.01	0.033	0.0488
Schistosoma mansoni	hypothetical protein	0.0137	0.0516	0.0765
Echinococcus multilocularis	shaker cognate	0.0055	0.0105	0.0248
Onchocerca volvulus		0.0137	0.0516	0.7208
Loa Loa (eye worm)	voltage-gated potassium channel	0.0055	0.0105	0.0103
Loa Loa (eye worm)	tubulin beta-4 chain	0.0161	0.0639	0.0637
Echinococcus multilocularis	voltage dependent calcium channel	0.0055	0.0105	0.0248
Brugia malayi	intermediate filament protein	0.0054	0.0096	0.0094
Echinococcus multilocularis	neuropeptide receptor	0.0137	0.0516	0.1239
Schistosoma mansoni	bifunctional dihydrofolate reductase-thymidylate synthase	0.0169	0.0679	0.1007
Schistosoma mansoni	inositol 145-trisphosphate receptor	0.0055	0.0105	0.0153
Echinococcus granulosus	heat shock protein 90	0.0131	0.0485	0.1163
Echinococcus granulosus	voltage dependent calcium channel	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0137	0.0516	0.1239
Schistosoma mansoni	hypothetical protein	0.0648	0.31	0.4608
Trypanosoma cruzi	dihydrofolate reductase-thymidylate synthase, putative	0.008	0.0231	0.3387
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0137	0.0516	0.1239
Brugia malayi	larval opioid receptor	0.0137	0.0516	0.0514
Loa Loa (eye worm)	G-protein coupled receptor	0.0137	0.0516	0.0514
Trypanosoma cruzi	heat shock protein 85, putative	0.0144	0.0553	0.8146
Echinococcus multilocularis	neuropeptides capa receptor	0.0137	0.0516	0.1239
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus granulosus	7tm_1 domain containing protein	0.0137	0.0516	0.1239
Leishmania major	dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B	0.0056	0.0109	0.0259
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Onchocerca volvulus		0.0137	0.0516	0.7208
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0137	0.0516	0.1239
Brugia malayi	hypothetical protein	0.0137	0.0516	0.0514
Onchocerca volvulus		0.0137	0.0516	0.7208
Schistosoma mansoni	tubulin subunit beta	0.0161	0.0639	0.0948
Brugia malayi	Intermediate filament tail domain containing protein	0.0054	0.0096	0.0094
Schistosoma mansoni	voltage-gated potassium channel KCNQ	0.0055	0.0105	0.0153
Loa Loa (eye worm)	hypothetical protein	0.0058	0.0118	0.0116
Echinococcus multilocularis	potassium voltage gated channel protein	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Giardia lamblia	Heat shock protein HSP 90-alpha	0.0131	0.0485	0.7581
Trypanosoma brucei	heat shock protein 90, putative	0.0144	0.0553	0.8151
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	integrin alpha ps	0.0067	0.0166	0.0395
Trypanosoma brucei	DNA polymerase IV, putative	0.0041	0.0034	0.0494
Echinococcus granulosus	adenosine deaminase	0.0086	0.0259	0.0621
Trypanosoma cruzi	heat shock protein 85, putative	0.0131	0.0485	0.7131
Echinococcus granulosus	Tubulin beta 2C chain	0.0161	0.0639	0.1534
Trypanosoma brucei	beta tubulin	0.0161	0.0639	0.9408
Echinococcus granulosus	endoplasmin	0.0131	0.0485	0.1163
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0648	0.31	0.7461
Schistosoma mansoni	calcium-activated potassium channel	0.0055	0.0105	0.0153
Echinococcus granulosus	potassium voltage gated channel subfamily D	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0002	0.0001
Echinococcus granulosus	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Trypanosoma brucei	inositol 1,4,5-trisphosphate receptor	0.0055	0.0105	0.1544
Trypanosoma brucei	DNA polymerase kappa, putative	0.0041	0.0034	0.0494
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0137	0.0516	0.0765
Brugia malayi	Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog	0.0055	0.0105	0.0103
Schistosoma mansoni	neuropeptide receptor	0.0137	0.0516	0.0765
Schistosoma mansoni	neuropeptide F-like receptor	0.0137	0.0516	0.0765
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0137	0.0516	0.0765
Loa Loa (eye worm)	hypothetical protein	0.0118	0.0422	0.042
Echinococcus granulosus	potassium channel KvQLT family member kqt 1	0.0055	0.0105	0.0248
Echinococcus granulosus	potassium voltage gated channel protein	0.0055	0.0105	0.0248
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0648	0.31	0.7461
Plasmodium falciparum	heat shock protein 90	0.0144	0.0553	0.8146
Toxoplasma gondii	hypothetical protein	0.0055	0.0105	0.1523
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Onchocerca volvulus	Adenosine deaminase homolog	0.0086	0.0259	0.281
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0055	0.0105	0.0153
Brugia malayi	Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit	0.0055	0.0105	0.0103
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0137	0.0516	0.7208
Echinococcus granulosus	voltage gated hydrogen channel 1	0.0055	0.0105	0.0248
Echinococcus granulosus	7TM GPCR rhodopsin	0.0137	0.0516	0.1239
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0055	0.0105	0.0153
Treponema pallidum	heat shock protein 90	0.0131	0.0485	1
Onchocerca volvulus		0.0137	0.0516	0.7208
Brugia malayi	G-protein coupled receptor	0.0137	0.0516	0.0514
Giardia lamblia	Beta tubulin	0.0161	0.0639	1
Echinococcus multilocularis	beta tubulin	0.0161	0.0639	0.1534
Echinococcus multilocularis	dna polymerase kappa	0.0041	0.0034	0.0077
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Brugia malayi	heat shock protein 90	0.0144	0.0553	0.0552
Echinococcus multilocularis	neuropeptides capa receptor	0.0137	0.0516	0.1239
Echinococcus multilocularis	lamin dm0	0.0054	0.0096	0.0226
Trypanosoma brucei	heat shock protein, putative	0.0144	0.0553	0.8151
Loa Loa (eye worm)	hypothetical protein	0.0558	0.2647	0.2646
Schistosoma mansoni	two-pore calcium channel	0.0055	0.0105	0.0153
Brugia malayi	cation channel family protein	0.0055	0.0105	0.0103
Echinococcus granulosus	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Trichomonas vaginalis	endoplasmin, putative	0.0041	0.0032	0.0475
Brugia malayi	follicle stimulating hormone receptor	0.0137	0.0516	0.0514
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0137	0.0516	0.0765
Loa Loa (eye worm)	calcium channel	0.0055	0.0105	0.0103
Echinococcus granulosus	serotonin receptor	0.0137	0.0516	0.1239
Echinococcus granulosus	muscleblind protein	0.0152	0.0592	0.1423
Echinococcus multilocularis	lamin	0.0054	0.0096	0.0226
Echinococcus granulosus	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	potassium voltage gated channel subfamily D	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0137	0.0516	0.0765
Schistosoma mansoni	heat shock protein	0.0144	0.0553	0.0821
Echinococcus multilocularis	heat shock protein	0.0144	0.0553	0.1329
Trypanosoma brucei	heat shock protein, putative	0.0144	0.0553	0.8151
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0055	0.0105	0.0103
Brugia malayi	beta-tubulin, identical	0.0161	0.0639	0.0637
Brugia malayi	neuropeptide F receptor	0.0137	0.0516	0.0514
Trypanosoma cruzi	beta tubulin, putative	0.0161	0.0639	0.9406
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Giardia lamblia	Grp94/Hsp90	0.0131	0.0485	0.7581
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0137	0.0516	0.0765
Toxoplasma gondii	beta-tubulin, putative	0.0161	0.0639	0.9406
Echinococcus multilocularis	fmrfamide receptor	0.0137	0.0516	0.1239
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Loa Loa (eye worm)	integrin alpha pat-2	0.0232	0.0997	0.0996
Plasmodium falciparum	tubulin beta chain	0.0161	0.0639	0.9406
Schistosoma mansoni	neuropeptide receptor	0.0285	0.1265	0.1879
Echinococcus granulosus	tubulin beta 1 chain	0.0161	0.0639	0.1534
Echinococcus granulosus	neuropeptide receptor A26	0.0137	0.0516	0.1239
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0137	0.0516	0.1239
Brugia malayi	Caveolin-1	0.0558	0.2647	0.2646
Onchocerca volvulus		0.0137	0.0516	0.7208
Echinococcus multilocularis	musashi	0.0054	0.0096	0.0226
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Echinococcus multilocularis	cyclic nucleotide gated cation channel	0.0055	0.0105	0.0248
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Echinococcus granulosus	transient receptor potential cation channel	0.0055	0.0105	0.0248
Echinococcus multilocularis	g protein coupled receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Onchocerca volvulus		0.0137	0.0516	0.7208
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Trichomonas vaginalis	heat shock protein, putative	0.0131	0.0485	0.7581
Plasmodium falciparum	bifunctional dihydrofolate reductase-thymidylate synthase	0.0169	0.0679	1
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0137	0.0516	0.0765
Schistosoma mansoni	serine-type protease inhibitor	0.0477	0.2237	0.3325
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0055	0.0105	0.0248
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Schistosoma mansoni	transient receptor potential channel	0.0055	0.0105	0.0153
Toxoplasma gondii	dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein	0.0056	0.0109	0.1586
Echinococcus multilocularis	transient receptor potential cation channel	0.0055	0.0105	0.0248
Brugia malayi	latrophilin 2 splice variant baaae	0.1365	0.6725	0.6724
Brugia malayi	ion channel NompC	0.0055	0.0105	0.0103
Schistosoma mansoni	amine GPCR	0.0137	0.0516	0.0765
Schistosoma mansoni	high voltage-activated calcium channel Cav2A	0.0055	0.0105	0.0153
Schistosoma mansoni	hypothetical protein	0.0055	0.0105	0.0153
Echinococcus multilocularis	G protein coupled receptor 139	0.0285	0.1265	0.3042
Echinococcus granulosus	dro:myosuppressin receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0152	0.0592	0.0591
Brugia malayi	Protein kinase domain containing protein	0.0169	0.0679	0.0677
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0137	0.0516	0.0765
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0137	0.0516	0.0514
Echinococcus granulosus	allatostatin A receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0042	0.004
Entamoeba histolytica	adenosine deaminase, putative	0.0086	0.0259	0.4047
Echinococcus granulosus	neuropeptides capa receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Echinococcus granulosus	integrin alpha ps	0.0067	0.0166	0.0395
Echinococcus granulosus	tubulin beta 4A class IVa	0.0161	0.0639	0.1534
Trypanosoma cruzi	heat shock protein 90, putative	0.0144	0.0553	0.8146
Loa Loa (eye worm)	voltage-gated calcium channel	0.0055	0.0105	0.0103
Brugia malayi	hypothetical protein	0.008	0.0231	0.0229
Echinococcus granulosus	cyclic nucleotide gated cation channel alpha 3	0.0055	0.0105	0.0248
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Mycobacterium tuberculosis	Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G)	0.0131	0.0485	0.0844
Echinococcus multilocularis	heat shock protein 90	0.0131	0.0485	0.1163
Loa Loa (eye worm)	ryanodine receptor	0.0055	0.0105	0.0103
Entamoeba histolytica	heat shock protein 90, putative	0.0144	0.0553	0.8661
Echinococcus granulosus	integrin alpha 3	0.0115	0.0408	0.0978
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0055	0.0105	0.0248
Schistosoma mansoni	opsin-like receptor	0.0137	0.0516	0.0765
Echinococcus granulosus	transient receptor potential cation channel	0.0055	0.0105	0.0248
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0137	0.0516	0.1239
Trypanosoma brucei	heat shock protein, putative	0.0144	0.0553	0.8151
Echinococcus granulosus	intermediate filament protein	0.0054	0.0096	0.0226
Brugia malayi	Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog	0.0055	0.0105	0.0103
Echinococcus granulosus	ryanodine receptor 44f	0.0055	0.0105	0.0248
Echinococcus granulosus	potassium voltage gated channel protein	0.0055	0.0105	0.0248
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0055	0.0105	0.0153
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Echinococcus granulosus	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Schistosoma mansoni	myosin xvIII	0.0137	0.0516	0.0765
Brugia malayi	Ryanodine Receptor TM 4-6 family protein	0.0055	0.0105	0.0103
Trypanosoma cruzi	dipeptidyl-peptidase 8-like serine peptidase	0.0056	0.0109	0.1586
Trypanosoma brucei	Voltage-dependent calcium channel subunit, putative	0.0055	0.0105	0.1544
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0137	0.0516	0.0765
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0648	0.31	0.7461
Mycobacterium ulcerans	adenosine deaminase	0.0086	0.0259	0.0705
Schistosoma mansoni	biogenic amine receptor	0.0137	0.0516	0.0765
Echinococcus multilocularis	voltage dependent calcium channel	0.0055	0.0105	0.0248
Echinococcus multilocularis	dipeptidyl aminopeptidaseprotein	0.0167	0.0671	0.1611
Echinococcus multilocularis	adenosine deaminase	0.0086	0.0259	0.0621
Brugia malayi	Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog	0.0055	0.0105	0.0103
Echinococcus multilocularis	integrin alpha 3	0.0115	0.0408	0.0978
Loa Loa (eye worm)	hypothetical protein	0.0058	0.0118	0.0116
Loa Loa (eye worm)	neuropeptide F receptor	0.0137	0.0516	0.0514
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0137	0.0516	0.0765
Mycobacterium tuberculosis	Probable adenosine deaminase Add (adenosine aminohydrolase)	0.0086	0.0259	0.0094
Schistosoma mansoni	vesicular amine transporter	0.0055	0.0105	0.0153
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Echinococcus granulosus	biogenic amine 5HT receptor	0.0137	0.0516	0.1239
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.0055	0.0105	0.0153
Leishmania major	calcium channel protein, putative,ion transporter, putative	0.0857	0.4154	1
Brugia malayi	Angiotensin-converting enzyme family protein	0.0165	0.0656	0.0655
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0137	0.0516	0.7208
Echinococcus multilocularis	g protein coupled receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0055	0.0105	0.0248
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0055	0.0105	0.0103
Echinococcus multilocularis	conserved hypothetical protein	0.0055	0.0105	0.0248
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	potassium:sodium hyperpolarization activated	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Mycobacterium tuberculosis	Probable thymidylate synthase ThyA (ts) (TSASE)	0.0169	0.0679	0.149
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Brugia malayi	ORL1-like opioid receptor	0.0137	0.0516	0.0514
Brugia malayi	Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog	0.0055	0.0105	0.0103
Brugia malayi	Endoplasmin precursor	0.0144	0.0553	0.0552
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Loa Loa (eye worm)	intermediate filament protein	0.0054	0.0096	0.0094
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Brugia malayi	prolyl oligopeptidase family protein	0.0056	0.0109	0.0107
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	cyclic nucleotide gated cation channel alpha 3	0.0055	0.0105	0.0248
Echinococcus granulosus	shaker cognate	0.0055	0.0105	0.0248
Brugia malayi	voltage-dependent calcium channel	0.0055	0.0105	0.0103
Loa Loa (eye worm)	angiotensin-converting enzyme family protein	0.0165	0.0656	0.0655
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0137	0.0516	0.1239
Brugia malayi	hypothetical protein	0.0137	0.0516	0.0514
Trypanosoma cruzi	heat shock protein 90, putative	0.0131	0.0485	0.7131
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0041	0.0034	0.0471
Echinococcus multilocularis	Dipeptidyl peptidase 9	0.0056	0.0109	0.0259
Echinococcus multilocularis	allatostatin A receptor	0.0137	0.0516	0.1239
Schistosoma mansoni	tubulin subunit beta	0.0161	0.0639	0.0948
Brugia malayi	Voltage-gated calcium channel, alpha subunit	0.0055	0.0105	0.0103
Entamoeba histolytica	tubulin family protein	0.0161	0.0639	1
Echinococcus multilocularis	neuropeptide receptor A26	0.0137	0.0516	0.1239
Leishmania major	lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative	0.0131	0.0485	0.1163
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0055	0.0105	0.0153
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Brugia malayi	hypothetical protein	0.0137	0.0516	0.0514
Trypanosoma brucei	DNA polymerase kappa, putative	0.0041	0.0034	0.0494
Brugia malayi	hypothetical protein	0.0055	0.0105	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Brugia malayi	hypothetical protein	0.0137	0.0516	0.0514
Trichomonas vaginalis	conserved hypothetical protein	0.008	0.0231	0.3601
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Loa Loa (eye worm)	thymidylate synthase	0.0169	0.0679	0.0677
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus granulosus	somatostatin receptor	0.0137	0.0516	0.1239
Echinococcus multilocularis	voltage dependent L type calcium channel subunit	0.0055	0.0105	0.0248
Toxoplasma gondii	bifunctional dihydrofolate reductase-thymidylate synthase	0.0169	0.0679	1
Echinococcus granulosus	heat shock protein 90	0.0144	0.0553	0.1329
Loa Loa (eye worm)	hypothetical protein	0.0083	0.0244	0.0243
Loa Loa (eye worm)	hypothetical protein	0.0114	0.04	0.0399
Echinococcus granulosus	hypothetical protein	0.0055	0.0105	0.0248
Trypanosoma brucei	DNA polymerase kappa, putative	0.0041	0.0034	0.0494
Trypanosoma brucei	14-3-3 protein 1	0.0035	0.0002	0.0025
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0137	0.0516	0.1239
Brugia malayi	cation channel family protein	0.0055	0.0105	0.0103
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Echinococcus multilocularis	short transient receptor potential channel 6	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0055	0.0105	0.1523
Echinococcus granulosus	neuropeptide Y receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Schistosoma mansoni	transient receptor potential channel	0.0055	0.0105	0.0153
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0161	0.0639	1
Echinococcus granulosus	neuropeptide Y receptor	0.0137	0.0516	0.1239
Echinococcus granulosus	two pore calcium channel protein 2	0.0055	0.0105	0.0248
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0137	0.0516	0.0514
Schistosoma mansoni	60S ribosomal protein L21	0.0055	0.0105	0.0153
Schistosoma mansoni	transient receptor potential channel	0.0055	0.0105	0.0153
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.0055	0.0105	0.0153
Onchocerca volvulus		0.0137	0.0516	0.7208
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0055	0.0105	0.0153
Echinococcus granulosus	GPCR family 2	0.0648	0.31	0.7461
Giardia lamblia	Heat shock protein HSP 90-alpha	0.0144	0.0553	0.8661
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Echinococcus multilocularis	transfer RNA-Gly	0.0055	0.0105	0.0248
Brugia malayi	Dopamine receptor protein 2	0.0137	0.0516	0.0514
Echinococcus granulosus	thymidylate synthase	0.0169	0.0679	0.1631
Entamoeba histolytica	heat shock protein 90, putative	0.0144	0.0553	0.8661
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0137	0.0516	0.1239
Brugia malayi	Tubulin beta-1 chain	0.0161	0.0639	0.0637
Echinococcus multilocularis	integrin alpha ps	0.0067	0.0166	0.0395
Echinococcus granulosus	hyperpolarization activated cyclic	0.0055	0.0105	0.0248
Loa Loa (eye worm)	tubulin beta-1 chain	0.0161	0.0639	0.0637
Echinococcus multilocularis	potassium voltage gated channel subfamily D	0.0055	0.0105	0.0248
Schistosoma mansoni	amine GPCR	0.0137	0.0516	0.0765
Loa Loa (eye worm)	TYRA-2 protein	0.0137	0.0516	0.0514
Schistosoma mansoni	growth hormone secretagogue receptor	0.0137	0.0516	0.0765
Brugia malayi	Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog	0.0055	0.0105	0.0103
Schistosoma mansoni	hypothetical protein	0.0648	0.31	0.4608
Mycobacterium tuberculosis	Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase	0.0675	0.3236	1
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0137	0.0516	0.0765
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Plasmodium vivax	heat shock protein 86, putative	0.0144	0.0553	0.7007
Trypanosoma cruzi	Voltage-dependent calcium channel subunit, putative	0.0055	0.0105	0.1523
Echinococcus granulosus	neuropeptide s receptor	0.0137	0.0516	0.1239
Schistosoma mansoni	amine GPCR	0.0137	0.0516	0.0765
Echinococcus granulosus	potassium voltage gated channel subfamily D	0.0055	0.0105	0.0248
Schistosoma mansoni	voltage-gated cation channel	0.0055	0.0105	0.0153
Onchocerca volvulus		0.0137	0.0516	0.7208
Trypanosoma brucei	heat shock protein, putative	0.0144	0.0553	0.8151
Echinococcus granulosus	voltage dependent calcium channel type d subunit\|voltage dependent calcium channel alpha 1	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0137	0.0516	0.0514
Onchocerca volvulus		0.0137	0.0516	0.7208
Schistosoma mansoni	biogenic amine receptor	0.0137	0.0516	0.0765
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0041	0.0034	0.0471
Echinococcus multilocularis	potassium large conductance calcium activated	0.0055	0.0105	0.0248
Echinococcus multilocularis	tubulin beta 1 chain	0.0161	0.0639	0.1534
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0137	0.0516	0.0765
Echinococcus granulosus	sodium channel protein	0.0857	0.4154	1
Toxoplasma gondii	hypothetical protein	0.0055	0.0105	0.1523
Brugia malayi	Dopamine receptor	0.0137	0.0516	0.0514
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0041	0.0034	0.0471
Trypanosoma brucei	14-3-3 protein 2	0.0035	0.0002	0.0025
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Trypanosoma brucei	serine peptidase, Clan SC, Family S9B	0.0056	0.0109	0.1607
Echinococcus granulosus	Dipeptidyl peptidase 9	0.0056	0.0109	0.0259
Toxoplasma gondii	beta tubulin	0.0161	0.0639	0.9406
Onchocerca volvulus		0.0137	0.0516	0.7208
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0137	0.0516	0.0765
Echinococcus granulosus	calcium activated potassium channel	0.0055	0.0105	0.0248
Trypanosoma brucei	dihydrofolate reductase-thymidylate synthase	0.0169	0.0679	1
Trichomonas vaginalis	heat shock protein, putative	0.0144	0.0553	0.8661
Brugia malayi	Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog	0.0055	0.0105	0.0103
Echinococcus granulosus	g protein coupled receptor	0.0137	0.0516	0.1239
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Echinococcus granulosus	transient receptor potential cation channel	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	voltage dependent calcium channel type d subunit	0.0055	0.0105	0.0248
Echinococcus granulosus	tubulin subunit beta	0.0161	0.0639	0.1534
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Brugia malayi	hypothetical protein	0.0137	0.0516	0.0514
Trichomonas vaginalis	tubulin beta chain, putative	0.0161	0.0639	1
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.0055	0.0105	0.0153
Echinococcus multilocularis	transient receptor potential cation channel	0.0055	0.0105	0.0248
Echinococcus granulosus	hyperpolarization activated cyclic	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0169	0.0679	0.0677
Echinococcus multilocularis	tubulin subunit beta	0.0161	0.0639	0.1534
Brugia malayi	Serotonin receptor	0.0137	0.0516	0.0514
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus granulosus	sodium leak channel non selective protein	0.0055	0.0105	0.0248
Toxoplasma gondii	beta-1 tubulin, putative	0.0161	0.0639	0.9406
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0648	0.31	0.7461
Brugia malayi	AKH receptor	0.0137	0.0516	0.0514
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0137	0.0516	0.0765
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0055	0.0105	0.0103
Brugia malayi	hypothetical protein	0.0137	0.0516	0.0514
Schistosoma mansoni	amine GPCR	0.0137	0.0516	0.0765
Mycobacterium leprae	PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G)	0.0131	0.0485	0.5367
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0055	0.0105	0.0248
Echinococcus multilocularis	calcium activated potassium channel	0.0055	0.0105	0.0248
Schistosoma mansoni	neuropeptide receptor	0.0137	0.0516	0.0765
Onchocerca volvulus	Transient receptor potential cation channel trpm homolog	0.0055	0.0105	0.0159
Giardia lamblia	Beta tubulin	0.0161	0.0639	1
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Toxoplasma gondii	Adenosine/AMP deaminase domain-containing protein	0.0086	0.0259	0.3806
Loa Loa (eye worm)	hypothetical protein	0.2013	1	1
Loa Loa (eye worm)	melatonin receptor type 1A	0.0137	0.0516	0.0514
Echinococcus granulosus	potassium large conductance calcium activated	0.0055	0.0105	0.0248
Schistosoma mansoni	hypothetical protein	0.0648	0.31	0.4608
Leishmania major	hypothetical protein, unknown function	0.0055	0.0105	0.0248
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Toxoplasma gondii	transporter, cation channel family protein	0.0055	0.0105	0.1523
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0137	0.0516	0.1239
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0137	0.0516	0.0765
Echinococcus multilocularis	Tubulin beta 2C chain	0.0161	0.0639	0.1534
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.0055	0.0105	0.0153
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0137	0.0516	0.0514
Schistosoma mansoni	lamin	0.0054	0.0096	0.014
Echinococcus multilocularis	voltage dependent L type calcium channel subunit	0.0055	0.0105	0.0248
Echinococcus multilocularis	potassium voltage gated channel subfamily D	0.0055	0.0105	0.0248
Brugia malayi	hypothetical protein	0.0043	0.0042	0.004
Echinococcus multilocularis	transient receptor potential gamma protein	0.0055	0.0105	0.0248
Brugia malayi	Transient-receptor-potential like protein	0.0055	0.0105	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0137	0.0516	0.0765
Echinococcus granulosus	neuropeptide FF receptor 2	0.0137	0.0516	0.1239
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.0055	0.0105	0.1523
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Brugia malayi	G-protein coupled receptor	0.0137	0.0516	0.0514
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Brugia malayi	sulfakinin receptor protein	0.0137	0.0516	0.0514
Trichomonas vaginalis	tubulin, putative	0.0161	0.0639	1
Brugia malayi	Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit	0.0055	0.0105	0.0103
Schistosoma mansoni	neuropeptide F-like receptor	0.0137	0.0516	0.0765
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0137	0.0516	0.0765
Echinococcus multilocularis	tubulin, beta 4A class IVa	0.0161	0.0639	0.1534
Echinococcus granulosus	two pore calcium channel protein 1	0.0055	0.0105	0.0248
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Trypanosoma brucei	RNA helicase, putative	0.01	0.033	0.4862
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0259	0.0258
Brugia malayi	Latrophilin receptor protein 2	0.0648	0.31	0.3099
Echinococcus multilocularis	g protein coupled receptor	0.0137	0.0516	0.1239
Schistosoma mansoni	neuropeptide receptor	0.0137	0.0516	0.0765
Echinococcus granulosus	tm gpcr rhodopsin	0.0137	0.0516	0.1239
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0137	0.0516	0.1239
Trichomonas vaginalis	heat shock protein, putative	0.0131	0.0485	0.7581
Echinococcus granulosus	neuropeptide receptor	0.0285	0.1265	0.3042
Loa Loa (eye worm)	heat shock protein 90	0.0144	0.0553	0.0552
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Echinococcus granulosus	potassium voltage gated channel protein	0.0055	0.0105	0.0248
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Schistosoma mansoni	intermediate filament proteins	0.0054	0.0096	0.014
Loa Loa (eye worm)	hypothetical protein	0.0152	0.0592	0.0591
Onchocerca volvulus		0.0137	0.0516	0.7208
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Echinococcus granulosus	orexin receptor type 2	0.0137	0.0516	0.1239
Loa Loa (eye worm)	neuropeptide F receptor	0.0137	0.0516	0.0514
Trypanosoma brucei	heat shock protein, putative	0.0144	0.0553	0.8151
Schistosoma mansoni	lamin	0.0054	0.0096	0.014
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Onchocerca volvulus		0.0137	0.0516	0.7208
Echinococcus multilocularis	potassium voltage gated channel subfamily C	0.0055	0.0105	0.0248
Trypanosoma brucei	DNA polymerase kappa, putative	0.0041	0.0034	0.0494
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0137	0.0516	0.1239
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Schistosoma mansoni	opsin-like receptor	0.0137	0.0516	0.0765
Echinococcus multilocularis	voltage dependent calcium channel type d subunit	0.0055	0.0105	0.0248
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.2013	1	1
Schistosoma mansoni	hypothetical protein	0.0137	0.0516	0.0765
Echinococcus multilocularis	orexin receptor type 2	0.0137	0.0516	0.1239
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0055	0.0105	0.1619
Trypanosoma brucei	beta tubulin	0.0161	0.0639	0.9408
Echinococcus granulosus	Tubulin beta 2C chain	0.0161	0.0639	0.1534
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0041	0.0034	0.05
Schistosoma mansoni	voltage-dependent calcium channel	0.0055	0.0105	0.0153
Schistosoma mansoni	serine-type protease inhibitor	0.0477	0.2237	0.3325
Trypanosoma cruzi	heat shock protein 90, putative	0.0117	0.0415	0.6103
Schistosoma mansoni	histamine h1 receptor	0.0137	0.0516	0.0765
Echinococcus multilocularis	serotonin receptor	0.0137	0.0516	0.1239
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Echinococcus granulosus	G protein coupled receptor 139	0.0137	0.0516	0.1239
Brugia malayi	RE15519p	0.0137	0.0516	0.0514
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Trichomonas vaginalis	DNA polymerase eta, putative	0.0041	0.0034	0.05
Echinococcus granulosus	beta tubulin	0.0161	0.0639	0.1534
Trichomonas vaginalis	heat shock protein, putative	0.0041	0.0032	0.0475
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Trypanosoma cruzi	heat shock protein 85, putative	0.0144	0.0553	0.8146
Schistosoma mansoni	opsin-like receptor	0.0137	0.0516	0.0765
Schistosoma mansoni	transient receptor potential channel 4	0.0055	0.0105	0.0153
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Loa Loa (eye worm)	voltage-dependent calcium channel	0.0055	0.0105	0.0103
Echinococcus multilocularis	Tubulin beta 2C chain	0.0161	0.0639	0.1534
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0137	0.0516	0.0765
Echinococcus granulosus	potassium voltage gated channel protein	0.0055	0.0105	0.0248
Echinococcus granulosus	voltage gated sodium channel Nav1 alpha subunit	0.0857	0.4154	1
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Loa Loa (eye worm)	hypothetical protein	0.0648	0.31	0.3099
Brugia malayi	Adenosine/AMP deaminase family protein	0.0086	0.0259	0.0258
Schistosoma mansoni	adenosine deaminase-related	0.0086	0.0259	0.0383
Loa Loa (eye worm)	hypothetical protein	0.1365	0.6725	0.6724
Schistosoma mansoni	tubulin subunit beta	0.0161	0.0639	0.0948
Trypanosoma brucei	DNA polymerase kappa, putative	0.0041	0.0034	0.0494
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Echinococcus granulosus	dna polymerase kappa	0.0041	0.0034	0.0077
Mycobacterium ulcerans	thymidylate synthase	0.0169	0.0679	0.2015
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0648	0.31	0.3099
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Trypanosoma brucei	heat shock protein, putative	0.0144	0.0553	0.8151
Onchocerca volvulus		0.0137	0.0516	0.7208
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Brugia malayi	Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog	0.0055	0.0105	0.0103
Schistosoma mansoni	amine GPCR	0.0137	0.0516	0.0765
Leishmania major	adenine aminohydrolase	0.0086	0.0259	0.0621
Trypanosoma brucei	DNA polymerase IV, putative	0.0041	0.0034	0.0494
Entamoeba histolytica	adenosine deaminase, putative	0.0086	0.0259	0.4047
Leishmania major	heat shock protein 83-1	0.0144	0.0553	0.1329
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Trichomonas vaginalis	adenosine deaminase, putative	0.0086	0.0259	0.4047
Trypanosoma cruzi	heat shock protein 85, putative	0.0144	0.0553	0.8146
Brugia malayi	Calcitonin receptor-like protein seb-1	0.2013	1	1
Echinococcus granulosus	TRP transient receptor potential channel	0.0055	0.0105	0.0248
Brugia malayi	hypothetical protein	0.0137	0.0516	0.0514
Trichomonas vaginalis	tubulin gamma chain, putative	0.0161	0.0639	1
Echinococcus multilocularis	potassium voltage gated channel protein	0.0055	0.0105	0.0248
Echinococcus multilocularis	two pore calcium channel protein 2	0.0055	0.0105	0.0248
Echinococcus granulosus	fmrfamide receptor	0.0137	0.0516	0.1239
Schistosoma mansoni	hypothetical protein	0.0137	0.0516	0.0765
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Schistosoma mansoni	tubulin subunit beta	0.0161	0.0639	0.0948
Echinococcus multilocularis	dro:myosuppressin receptor	0.0137	0.0516	0.1239
Echinococcus multilocularis	Tubulin beta 2C chain	0.0161	0.0639	0.1534
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0161	0.0639	1
Brugia malayi	hypothetical protein	0.0137	0.0516	0.0514
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0137	0.0516	0.0765
Echinococcus granulosus	voltage dependent calcium channel type d subunit\|voltage dependent calcium channel\|voltage dependent L type calcium channel subu	0.0055	0.0105	0.0248
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0055	0.0105	0.0248
Trypanosoma cruzi	serine peptidase, Clan SC, Family S9B	0.0056	0.0109	0.1586
Brugia malayi	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	transient receptor potential cation channel	0.0055	0.0105	0.0248
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0137	0.0516	0.1239
Loa Loa (eye worm)	BEN-1 protein	0.0161	0.0639	0.0637
Echinococcus multilocularis	g-protein coupled receptor	0.0137	0.0516	0.1239
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0137	0.0516	0.0765
Echinococcus multilocularis	thymidylate synthase	0.0169	0.0679	0.1631
Schistosoma mansoni	tubulin subunit beta	0.0161	0.0639	0.0948
Echinococcus multilocularis	serotonin receptor	0.0137	0.0516	0.1239
Echinococcus granulosus	lamin dm0	0.0054	0.0096	0.0226
Loa Loa (eye worm)	tubulin beta-2A chain	0.0161	0.0639	0.0637
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Plasmodium falciparum	endoplasmin, putative	0.0041	0.0032	0.0446
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0137	0.0516	0.0514
Echinococcus granulosus	transient receptor potential cation channel	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Entamoeba histolytica	tubulin family protein	0.0161	0.0639	1
Echinococcus granulosus	g-protein coupled receptor	0.0137	0.0516	0.1239
Echinococcus granulosus	sex peptide receptor	0.0137	0.0516	0.1239
Echinococcus granulosus	Tubulin beta 2C chain	0.0161	0.0639	0.1534
Echinococcus multilocularis	neuropeptide Y receptor	0.0137	0.0516	0.1239
Schistosoma mansoni	adenosine deaminase	0.0086	0.0259	0.0383
Loa Loa (eye worm)	hypothetical protein	0.0058	0.0118	0.0116
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0137	0.0516	0.0514
Echinococcus granulosus	lamin	0.0054	0.0096	0.0226
Echinococcus granulosus	transient receptor potential gamma protein	0.0055	0.0105	0.0248
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0137	0.0516	0.0514
Plasmodium vivax	endoplasmin, putative	0.0144	0.0553	0.7007
Echinococcus granulosus	Tubulin beta 2C chain	0.0161	0.0639	0.1534
Brugia malayi	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	potassium voltage gated channel subfamily A	0.0055	0.0105	0.0248
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0055	0.0105	0.0153
Echinococcus multilocularis	Tubulin beta 2C chain	0.0161	0.0639	0.1534
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	beta tubulin	0.0161	0.0639	0.1534
Schistosoma mansoni	integrin alpha-ps	0.0067	0.0166	0.0244
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0137	0.0516	0.1239
Loa Loa (eye worm)	beta-tubulin	0.0161	0.0639	0.0637
Schistosoma mansoni	hypothetical protein	0.0648	0.31	0.4608
Trichomonas vaginalis	heat shock protein, putative	0.0131	0.0485	0.7581
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0055	0.0105	0.1619
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Echinococcus multilocularis	muscleblind protein 1	0.0152	0.0592	0.1423
Brugia malayi	Serotonin receptor	0.0137	0.0516	0.0514
Toxoplasma gondii	Adenosine/AMP deaminase domain-containing protein	0.0086	0.0259	0.3806
Giardia lamblia	Beta tubulin	0.0161	0.0639	1
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0137	0.0516	0.0765
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0137	0.0516	0.1239
Schistosoma mansoni	neuropeptide f receptor 76f	0.0137	0.0516	0.0765
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0137	0.0516	0.1239
Brugia malayi	GnHR receptor homolog	0.1028	0.5019	0.5018
Brugia malayi	neuropeptide F receptor	0.0137	0.0516	0.0514
Echinococcus multilocularis	neuropeptide Y receptor	0.0137	0.0516	0.1239
Echinococcus granulosus	voltage gated potassium channel	0.0055	0.0105	0.0248
Schistosoma mansoni	high voltage-activated calcium channel Cav1	0.0055	0.0105	0.0153
Onchocerca volvulus		0.0169	0.0679	1
Toxoplasma gondii	heat shock protein HSP90	0.0144	0.0553	0.8146
Schistosoma mansoni	heat shock protein	0.0144	0.0553	0.0821
Onchocerca volvulus		0.0137	0.0516	0.7208
Echinococcus granulosus	tm gpcr rhodopsin	0.0137	0.0516	0.1239
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0055	0.0105	0.0248
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0055	0.0105	0.0248
Echinococcus granulosus	heat shock protein	0.0144	0.0553	0.1329
Loa Loa (eye worm)	tubulin beta chain	0.0161	0.0639	0.0637
Schistosoma mansoni	voltage-gated potassium channel	0.0055	0.0105	0.0153
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Trypanosoma brucei	heat shock protein, putative	0.0144	0.0553	0.8151
Echinococcus multilocularis	ryanodine receptor 44f	0.0055	0.0105	0.0248
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0055	0.0105	0.0248
Echinococcus multilocularis	Tubulin beta 2C chain	0.0161	0.0639	0.1534
Schistosoma mansoni	hypothetical protein	0.0137	0.0516	0.0765
Echinococcus multilocularis	voltage gated potassium channel	0.0055	0.0105	0.0248
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	GPCR, family 2	0.0648	0.31	0.7461
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0105	0.0103
Echinococcus granulosus	voltage dependent calcium channel	0.0055	0.0105	0.0248
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0137	0.0516	0.1239
Schistosoma mansoni	calcium channel voltage-dependent p/q type alpha 1a-related	0.0055	0.0105	0.0153
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0137	0.0516	0.1239
Leishmania major	beta tubulin	0.0161	0.0639	0.1534
Leishmania major	dihydrofolate reductase-thymidylate synthase	0.0169	0.0679	0.1631
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0137	0.0516	0.1239
Echinococcus multilocularis	endoplasmin	0.0131	0.0485	0.1163
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0516	0.0514
Echinococcus multilocularis	voltage gated hydrogen channel 1	0.0055	0.0105	0.0248

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 197.56 uM	Inhibition of MAOB in rat liver homogenates preincubated for 60 mins	ChEMBL.	18980841
IC50 (binding)	= 200.56 uM	Inhibition of MAOA in rat liver homogenates preincubated for 60 mins	ChEMBL.	18980841

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL521219

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1018199