Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | WEE1 G2 checkpoint kinase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0069 | 1 | 1 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.0053 | 0.743 | 1 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.0046 | 0.6245 | 0.8404 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.694 | 0.934 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.5784 | 0.7784 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.694 | 0.934 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.694 | 0.934 |
Leishmania major | fk506-binding protein 1-like protein | 0.0053 | 0.743 | 0.743 |
Mycobacterium tuberculosis | Probable trigger factor (TF) protein Tig | 0.0007 | 0 | 0.5 |
Schistosoma mansoni | solute carrier family 12 electroneutral k-cl cotransporter | 0.005 | 0.694 | 0.934 |
Leishmania major | peptidylprolyl isomerase-like protein | 0.0053 | 0.743 | 0.743 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0053 | 0.743 | 1 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0007 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.0007 | 0 | 0.5 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type, putative | 0.0053 | 0.743 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.0053 | 0.743 | 0.743 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.0046 | 0.6245 | 0.8404 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0069 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.694 | 0.934 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.0053 | 0.743 | 1 |
Trypanosoma brucei | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0053 | 0.743 | 0.743 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.694 | 0.934 |
Onchocerca volvulus | 0.0007 | 0 | 0.5 | |
Mycobacterium leprae | PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG | 0.0007 | 0 | 0.5 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase FKBP35 | 0.0053 | 0.743 | 1 |
Toxoplasma gondii | peptidyl-prolyl isomerase FKBP12, putative | 0.0007 | 0 | 0.5 |
Brugia malayi | Amino acid permease family protein | 0.005 | 0.694 | 0.934 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.5784 | 0.7784 |
Loa Loa (eye worm) | amino acid permease | 0.005 | 0.694 | 0.934 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.5784 | 0.7784 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.0007 | 0 | 0.5 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0007 | 0 | 0.5 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0069 | 1 | 1 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) | 0.0053 | 0.743 | 1 |
Chlamydia trachomatis | peptidyl-prolyl cis-trans isomerase | 0.0007 | 0 | 0.5 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.0053 | 0.743 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.694 | 0.934 |
Schistosoma mansoni | immunophilin | 0.0053 | 0.743 | 1 |
Echinococcus multilocularis | fk506 binding protein | 0.0053 | 0.743 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.5784 | 0.7784 |
Schistosoma mansoni | immunophilin | 0.0046 | 0.6245 | 0.8404 |
Onchocerca volvulus | 0.0007 | 0 | 0.5 | |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.0053 | 0.743 | 0.743 |
Brugia malayi | Hypothetical 112.3 kDa protein K02A2.3 in chromosome II | 0.005 | 0.694 | 0.934 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 | 0.0053 | 0.743 | 1 |
Echinococcus multilocularis | solute carrier family 12 | 0.005 | 0.694 | 0.934 |
Schistosoma mansoni | immunophilin FK506 binding protein FKBP12 | 0.0053 | 0.743 | 1 |
Trichomonas vaginalis | immunophilin, putative | 0.0053 | 0.743 | 1 |
Trypanosoma brucei | wee1-like protein kinase | 0.0069 | 1 | 1 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.0053 | 0.743 | 0.743 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0053 | 0.743 | 0.743 |
Schistosoma mansoni | immunophilin | 0.0053 | 0.743 | 1 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0053 | 0.743 | 1 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 | 0.0053 | 0.743 | 1 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0007 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 12 | 0.005 | 0.694 | 0.934 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.0053 | 0.743 | 1 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0069 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.5784 | 0.7784 |
Giardia lamblia | 70 kDa peptidylprolyl isomerase, putative | 0.0053 | 0.743 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.694 | 0.934 |
Mycobacterium ulcerans | FK-506 binding protein, peptidyl-prolyl cis-trans isomerase | 0.0053 | 0.743 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.5784 | 0.7784 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.6245 | 0.8404 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-12 | 0.0053 | 0.743 | 1 |
Plasmodium vivax | 70 kDa peptidylprolyl isomerase, putative | 0.0053 | 0.743 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.5784 | 0.7784 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type , putative | 0.0053 | 0.743 | 1 |
Loa Loa (eye worm) | FKBP5 protein | 0.0053 | 0.743 | 1 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP1A | 0.0053 | 0.743 | 1 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0053 | 0.743 | 0.743 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.