Detailed information for compound 1020129

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 580.795 | Formula: C27H48O9S2
  • H donors: 3 H acceptors: 7 LogP: 6.03 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(CCC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC[C@@H]2[C@]1(C)CC[C@H]([C@@H]2O)OS(=O)(=O)O)COS(=O)(=O)O)C
  • InChi: 1S/C27H48O9S2/c1-17(2)6-5-7-18(16-35-37(29,30)31)20-10-11-21-19-8-9-23-25(28)24(36-38(32,33)34)13-15-27(23,4)22(19)12-14-26(20,21)3/h17-25,28H,5-16H2,1-4H3,(H,29,30,31)(H,32,33,34)/t18-,19-,20+,21-,22-,23-,24+,25+,26+,27+/m0/s1
  • InChiKey: MYGOSFLYSKNPPC-PFXUIZMDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0146 0.236 0.3795
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0439 0.7733 1
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.0033 0.0291 0.0465
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0138 0.2211 0.3557
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0138 0.2211 0.286
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0182 0.0235
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0137 0.2196 0.3531
Onchocerca volvulus Notchless protein homolog 0.0128 0.2043 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0409 0.0409
Echinococcus multilocularis proteasome 26s subunit subunit 4 atpase 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0099 0.1509 0.1894
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0027 0.0182 0.0182
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0017 0.0002 0.0003
Brugia malayi proteasome subunit alpha type 4 0.0113 0.1762 0.1762
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0138 0.2211 0.3555
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0598 0.0773
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0135 0.217 0.3489
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0025 0.0138 0.0178
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.0028 0.0203 0.0203
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0034 0.03 0.0388
Trypanosoma brucei carbonic anhydrase-like protein 0.0146 0.2358 0.3792
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0409 0.0529
Toxoplasma gondii PCI domain-containing protein 0.0034 0.03 0.0483
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.0028 0.0203 0.0323
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0121 0.19 0.3054
Echinococcus multilocularis netrin receptor unc 5 0.0031 0.025 0.0324
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0054 0.0678 0.0678
Plasmodium vivax glutathione reductase, putative 0.0041 0.0446 0.0717
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.0027 0.0189 0.0189
Echinococcus multilocularis carbonic anhydrase 0.0054 0.0678 0.0877
Echinococcus multilocularis Mastin 0.0032 0.0278 0.0359
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.0026 0.0162 0.0209
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0122 0.1926 0.2491
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0028 0.0203 0.0262
Loa Loa (eye worm) beta-lactamase 0.0039 0.0409 0.0409
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0113 0.1765 0.2836
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0122 0.1926 0.3097
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0121 0.19 0.3056
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0598 0.0773
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0138 0.2211 0.2211
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0169 0.2792 0.3611
Echinococcus multilocularis carbonic anhydrase II 0.0146 0.2358 0.305
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0032 0.0278 0.0359
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0127 0.201 0.323
Schistosoma mansoni cercarial elastase (S01 family) 0.0032 0.0278 0.0359
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.0037 0.0366 0.0588
Loa Loa (eye worm) hypothetical protein 0.0027 0.0182 0.0182
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0031 0.025 0.0324
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0027 0.0182 0.0889
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.0026 0.0162 0.0258
Entamoeba histolytica proteasome regulatory subunit, putative 0.0028 0.0203 0.0323
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 4 0.0018 0.002 0.0026
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0137 0.2196 0.284
Schistosoma mansoni hypothetical protein 0.0075 0.1061 0.1371
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0122 0.1926 0.3099
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0127 0.2024 0.3254
Toxoplasma gondii 26S proteasome regulatory subunit, S6a family AAA ATpase 0.0018 0.0021 0.0033
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0054 0.0678 0.0678
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0121 0.19 0.3054
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0032 0.0278 0.0359
Loa Loa (eye worm) hypothetical protein 0.0184 0.3061 0.3061
Echinococcus multilocularis transmembrane protease serine 3 0.0032 0.0278 0.0359
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0122 0.1926 0.3097
Entamoeba histolytica proteasome regulatory subunit, putative 0.0018 0.002 0.0029
Trypanosoma cruzi trypanothione reductase, putative 0.0041 0.0446 0.0717
Schistosoma mansoni hypothetical protein 0.0165 0.2711 0.3506
Plasmodium vivax proteasome subunit beta type-1, putative 0.0146 0.236 0.3795
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0146 0.236 0.3051
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0409 0.0655
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0146 0.236 0.3051
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.0031 0.0257 0.0411
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0121 0.19 0.2457
Toxoplasma gondii peptidase, T1 family protein 0.0128 0.2043 0.3286
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0026 0.0162 0.0162
Schistosoma mansoni cercarial elastase (S01 family) 0.0032 0.0278 0.0359
Schistosoma mansoni hypothetical protein 0.0054 0.0678 0.0877
Plasmodium vivax proteasome subunit beta type-2, putative 0.0122 0.1926 0.3099
Loa Loa (eye worm) proteasome Regulatory Particle 0.0028 0.0203 0.0203
Schistosoma mansoni cercarial elastase (S01 family) 0.0032 0.0278 0.0359
Entamoeba histolytica hypothetical protein 0.0033 0.0291 0.0465
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0135 0.217 0.3491
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0105 0.1613 0.2073
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0025 0.0138 0.0222
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0099 0.1509 0.2427
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0041 0.0446 0.0063
Loa Loa (eye worm) hypothetical protein 0.0025 0.0138 0.0138
Schistosoma mansoni hypothetical protein 0.0184 0.3061 0.3958
Schistosoma mansoni hypothetical protein 0.0032 0.0278 0.0359
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0018 0.0021 0.0027
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0127 0.201 0.3232
Leishmania major proteasome beta 7 subunit, putative 0.0121 0.19 0.3056
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0409 0.0409
Loa Loa (eye worm) proteasome subunit beta type 1 0.0146 0.236 0.236
Onchocerca volvulus 0.0039 0.0409 0.2002
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0127 0.2017 0.2609
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0122 0.1926 0.3099
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0169 0.2792 0.4491
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0182 0.0182
Toxoplasma gondii proteasome subunit 0.0127 0.2024 0.3256
Giardia lamblia 20S proteasome alpha subunit 6 0.0127 0.201 0.323
Echinococcus granulosus ecdysone induced protein 78C 0.0027 0.0182 0.0235
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.0034 0.03 0.048
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0121 0.19 0.3056
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0409 0.0221
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0301 0.5209 0.6736
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0018 0.0011 0.0018
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.0026 0.016 0.0254
Brugia malayi beta-lactamase 0.0039 0.0409 0.0409
Toxoplasma gondii 26S protease regulatory subunit 4, putative 0.0017 0.0002 0.0003
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.0028 0.0204 0.0329
Schistosoma mansoni hypothetical protein 0.0037 0.0365 0.0472
Leishmania major proteasome alpha 2 subunit, putative 0.0131 0.2096 0.3371
Loa Loa (eye worm) glutathione reductase 0.0041 0.0446 0.0446
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0131 0.2096 0.2096
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.0031 0.0257 0.0414
Echinococcus multilocularis proteasome (prosome, macropain) 0.0356 0.6217 0.804
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.025 0.025
Brugia malayi Proteasome A-type and B-type family protein 0.0356 0.6217 0.6217
Trypanosoma cruzi 20S proteasome subunit 0.0122 0.1926 0.3099
Brugia malayi Adhesion regulating molecule conserved region family protein 0.0081 0.117 0.117
Loa Loa (eye worm) hypothetical protein 0.0039 0.0409 0.0409
Echinococcus multilocularis ecdysone induced protein 78C 0.0027 0.0182 0.0235
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0121 0.19 0.3056
Toxoplasma gondii 26s proteasome subunit p55, putative 0.0028 0.0204 0.0329
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.0026 0.016 0.0206
Brugia malayi proteasome subunit alpha type 6 0.0138 0.2211 0.2211
Echinococcus granulosus adhesion regulating molecule 1 0.0081 0.117 0.1513
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0128 0.2043 0.2642
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0127 0.2024 0.2618
Schistosoma mansoni coup transcription factor 0.0027 0.0182 0.0235
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0127 0.2017 0.2609
Schistosoma mansoni ankyrin 23/unc44 0.0031 0.025 0.0324
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0037 0.0366 0.0473
Loa Loa (eye worm) hypothetical protein 0.0027 0.0182 0.0182
Plasmodium vivax proteasome subunit beta type-7, putative 0.0135 0.217 0.3491
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0135 0.217 0.3489
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.0034 0.03 0.03
Echinococcus granulosus Proteasome subunit alpha beta 0.0128 0.2043 0.2642
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0135 0.217 0.3491
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0032 0.0278 0.0359
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0137 0.2196 0.3531
Brugia malayi proteasome subunit beta type 3 0.0122 0.1926 0.1926
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0017 0.0002 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0182 0.0235
Brugia malayi PCI domain containing protein 0.0026 0.016 0.016
Leishmania major proteasome alpha 3 subunit, putative 0.0127 0.2017 0.3245
Loa Loa (eye worm) hypothetical protein 0.0054 0.0678 0.0678
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0037 0.0366 0.0588
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0122 0.1926 0.3097
Echinococcus granulosus 26s protease regulatory subunit 6a 0.0018 0.0021 0.0027
Toxoplasma gondii hypothetical protein 0.0054 0.0678 0.109
Mycobacterium ulcerans proteasome PrcB 0.0356 0.6217 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0027 0.0182 0.0182
Giardia lamblia 20S proteasome alpha subunit 7 0.0128 0.2043 0.3284
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.0028 0.0203 0.0326
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0122 0.1926 0.3099
Schistosoma mansoni hypothetical protein 0.0026 0.016 0.0206
Schistosoma mansoni cercarial elastase (S01 family) 0.0032 0.0278 0.0359
Leishmania major hypothetical protein, conserved 0.0039 0.0409 0.0658
Loa Loa (eye worm) trypsin family protein 0.0032 0.0278 0.0278
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0037 0.0366 0.0473
Plasmodium vivax thioredoxin reductase, putative 0.0041 0.0446 0.0717
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.0026 0.0162 0.026
Loa Loa (eye worm) hypothetical protein 0.0025 0.0138 0.0138
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.068 0.068
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0137 0.2196 0.3531
Entamoeba histolytica hypothetical protein 0.0035 0.0328 0.0525
Echinococcus granulosus subfamily T1A non peptidase ue 0.0137 0.2196 0.284
Entamoeba histolytica hypothetical protein 0.0035 0.0328 0.0525
Echinococcus multilocularis carbonic anhydrase 0.0054 0.0678 0.0877
Echinococcus granulosus Proteasome subunit alpha type 7 0.0169 0.2792 0.3611
Echinococcus multilocularis FTZ F1 alpha 0.0027 0.0182 0.0235
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.0031 0.0257 0.0414
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0128 0.2043 0.3284
Trypanosoma brucei proteasome beta 6 subunit 0.0146 0.236 0.3794
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0027 0.0182 0.0182
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0365 0.0365
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0027 0.0182 0.0235
Trichomonas vaginalis 26S proteasome subunit, putative 0.0026 0.016 0.0254
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0182 0.0235
Loa Loa (eye worm) hypothetical protein 0.0027 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0039 0.0409 0.0409
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0409 0.0221
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0127 0.2024 0.3254
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0328 0.0424
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0018 0.002 0.0032
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0122 0.1926 0.2491
Loa Loa (eye worm) hypothetical protein 0.0032 0.0278 0.0278
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0128 0.2043 0.3284
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0127 0.2017 0.3245
Brugia malayi Proteasome A-type and B-type family protein 0.0439 0.7733 0.7733
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0137 0.2196 0.2196
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0146 0.236 0.3795
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0121 0.19 0.3056
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0409 0.0655
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0018 0.002 0.0032
Toxoplasma gondii hypothetical protein 0.0023 0.0103 0.0166
Echinococcus granulosus proteasome subunit beta type 7 0.0439 0.7733 1
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0032 0.0278 0.0359
Echinococcus granulosus 26S proteasome regulatory subunit T3 0.0017 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0027 0.0182 0.0182
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0025 0.0138 0.0219
Brugia malayi Protein kinase domain containing protein 0.0031 0.025 0.025
Echinococcus granulosus proteasome subunit beta type 6 0.0127 0.2024 0.2618
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0099 0.1509 0.2427
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0099 0.1509 0.5
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0032 0.0278 0.0359
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0099 0.1509 0.1951
Leishmania major proteasome alpha 7 subunit, putative 0.0169 0.2792 0.4491
Toxoplasma gondii 26S proteasome regulatory subunit 6b, putative 0.0017 0.0002 0.0003
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0137 0.2196 0.3531
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0127 0.2024 0.3256
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0128 0.2043 0.2642
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0027 0.0182 0.0182
Schistosoma mansoni carbonic anhydrase-related 0.0054 0.0678 0.0877
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0122 0.1926 0.3097
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.0026 0.0162 0.026
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0095 0.1419 0.174
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0356 0.6217 1
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0127 0.201 0.3232
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.0028 0.0204 0.0264
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0127 0.2017 0.3243
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0131 0.2096 0.3369
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0131 0.2096 0.271
Brugia malayi Proteasome A-type and B-type family protein 0.0127 0.2024 0.2024
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0127 0.2024 0.3254
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.0037 0.0366 0.0588
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.0033 0.0291 0.0468
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0054 0.0678 0.0678
Brugia malayi Proteasome A-type and B-type family protein 0.0121 0.19 0.19
Entamoeba histolytica proteasome regulatory subunit, putative 0.0026 0.016 0.0254
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0169 0.2792 0.449
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0025 0.0138 0.0222
Loa Loa (eye worm) PAS-3 protein 0.0113 0.1762 0.1762
Schistosoma mansoni cercarial elastase (S01 family) 0.0032 0.0278 0.0359
Loa Loa (eye worm) hypothetical protein 0.0054 0.068 0.068
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0138 0.2211 0.3555
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0146 0.2358 0.2358
Loa Loa (eye worm) hypothetical protein 0.0054 0.0678 0.0678
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0137 0.2196 0.3533
Trypanosoma brucei proteasome regulatory ATPase subunit 5 0.0018 0.0021 0.0031
Loa Loa (eye worm) hypothetical protein 0.0037 0.0365 0.0365
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.0028 0.0203 0.0326
Onchocerca volvulus 0.0032 0.0278 0.136
Echinococcus granulosus proteasome subunit alpha type 6 0.0138 0.2211 0.286
Trichomonas vaginalis 26S proteasome regulatory subunit rpn1, putative 0.0019 0.004 0.0061
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.0037 0.0366 0.0473
Schistosoma mansoni cercarial elastase (S01 family) 0.0032 0.0278 0.0359
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.0028 0.0204 0.0264
Schistosoma mansoni carbonic anhydrase 0.0054 0.0678 0.0877
Entamoeba histolytica proteasome regulatory subunit, putative 0.0034 0.03 0.048
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0122 0.1926 0.3097
Leishmania major carbonic anhydrase-like protein 0.0146 0.2358 0.3793
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0252 0.0326
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.0026 0.016 0.0256
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0034 0.03 0.0388
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0123 0.1941 0.251
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0356 0.6217 1
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0018 0.0021 0.0033
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0146 0.236 0.3795
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.0026 0.016 0.0206
Leishmania major proteasome regulatory ATPase subunittcc1l8.3, putative 0.0017 0.0002 0.0003
Echinococcus multilocularis carbonic anhydrase 0.0054 0.0678 0.0877
Onchocerca volvulus 0.0027 0.0182 0.0889
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0131 0.2096 0.3371
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0169 0.2792 0.4491
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.0034 0.03 0.0483
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0027 0.0182 0.0235
Brugia malayi ecdysteroid receptor 0.0027 0.0182 0.0182
Schistosoma mansoni netrin receptor unc5 0.0031 0.025 0.0324
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.0028 0.0204 0.0329
Brugia malayi beta-lactamase family protein 0.0039 0.0409 0.0409
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.0034 0.03 0.0483
Echinococcus granulosus netrin receptor unc 5 0.0031 0.025 0.0324
Schistosoma mansoni cercarial elastase (S01 family) 0.0032 0.0278 0.0359
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0169 0.2792 0.449
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0099 0.1509 0.2427
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.0028 0.0203 0.0323
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0095 0.1419 0.174
Loa Loa (eye worm) hypothetical protein 0.0032 0.0278 0.0278
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0127 0.2024 0.2024
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0105 0.1613 0.2073
Mycobacterium tuberculosis Probable dehydrogenase 0.0095 0.1419 0.174
Brugia malayi proteasome subunit alpha type 3 0.0128 0.2043 0.2043
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.0026 0.0162 0.0258
Toxoplasma gondii PCI domain-containing protein 0.0026 0.016 0.0256
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0137 0.2196 0.3533
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0025 0.0138 0.0178
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0025 0.0138 0.0178
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0032 0.0278 0.0359
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.0037 0.0366 0.0588
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0128 0.2043 0.2043
Schistosoma mansoni cercarial elastase (S01 family) 0.0032 0.0278 0.0359
Schistosoma mansoni hypothetical protein 0.0032 0.0278 0.0359
Leishmania major proteasome alpha 7 subunit, putative 0.0128 0.2043 0.3286
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0121 0.19 0.3056
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0121 0.19 0.2457
Echinococcus granulosus carbonic anhydrase 0.0054 0.0678 0.0877
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0026 0.0162 0.0258
Brugia malayi 20S proteasome alpha5 subunit 0.0137 0.2196 0.2196
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0054 0.0678 0.0678
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0095 0.1419 0.174
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0027 0.0182 0.0235
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.0026 0.0162 0.0209
Schistosoma mansoni hypothetical protein 0.0031 0.025 0.0324
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.0034 0.03 0.0388
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0131 0.2096 0.3371
Trypanosoma brucei proteasome alpha 7 subunit 0.0128 0.2043 0.3284
Brugia malayi Ubiquitin interaction motif family protein 0.0018 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0054 0.0678 0.0678
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0182 0.0235
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0042 0.0459 0.0738
Plasmodium vivax 26S proteasome AAA-ATPase subunit RPT3, putative 0.0017 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0182 0.0182
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0598 0.0773
Brugia malayi Uncoordinated protein 44 0.0031 0.025 0.025
Echinococcus multilocularis Ankyrin 0.0031 0.0252 0.0326
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0081 0.117 0.1882
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0099 0.1509 0.2427
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.0028 0.0203 0.0323
Leishmania major proteasome beta 3 subunit, putative 0.0122 0.1926 0.3099
Brugia malayi 26S protease regulatory subunit 6A 0.0018 0.0021 0.0021
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.0034 0.03 0.0388
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0018 0.0021 0.0031
Leishmania major proteasome beta-1 subunit, putative 0.0127 0.2024 0.3256
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0122 0.1926 0.2491
Loa Loa (eye worm) hypothetical protein 0.0027 0.0182 0.0182
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0138 0.2211 0.3557
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0138 0.2211 0.3555
Giardia lamblia 20S proteasome alpha subunit 5 0.0137 0.2196 0.3531
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0131 0.2096 0.3369
Brugia malayi hypothetical protein 0.0035 0.0328 0.0328
Toxoplasma gondii proteasome subunit alpha1, putative 0.0138 0.2211 0.3557
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0146 0.236 0.3795
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0027 0.0182 0.0235
Schistosoma mansoni 26S proteasome subunit S9 0.0031 0.0257 0.0333
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0027 0.0182 0.0235
Onchocerca volvulus 0.0039 0.0409 0.2002
Toxoplasma gondii SAC3/GANP family protein 0.0025 0.0138 0.0222
Mycobacterium ulcerans lipase LipD 0.0039 0.0409 0.0221
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.0037 0.0366 0.0585
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0182 0.0235
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0127 0.201 0.2599
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0027 0.0182 0.0182
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.0028 0.0203 0.0262
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.0075 0.1061 0.1371
Echinococcus granulosus Ankyrin 0.0031 0.0252 0.0326
Plasmodium falciparum carbonic anhydrase 0.0054 0.0678 0.109
Schistosoma mansoni multiubiquitin binding protein S5a 0.0018 0.002 0.0026
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0127 0.201 0.2599
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0137 0.2196 0.3533
Brugia malayi Trypsin family protein 0.0032 0.0278 0.0278
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0127 0.2017 0.3243
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0356 0.6217 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0027 0.0182 0.0235
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0328 0.0424
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0131 0.2096 0.3371
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.0028 0.0204 0.0329
Loa Loa (eye worm) hypothetical protein 0.0017 0.0000099825 0.0000099825
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0409 0.0529
Schistosoma mansoni proteasome regulatory subunit-related 0.0028 0.0204 0.0264
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0598 0.0598
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0128 0.2043 0.3286
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0032 0.0278 0.0359
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0026 0.016 0.0256
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0356 0.6217 0.804
Onchocerca volvulus 0.0032 0.0278 0.136
Brugia malayi Trypsin-like protease protein 5 0.0032 0.0278 0.0278
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0105 0.1613 0.2073
Plasmodium falciparum 26S protease regulatory subunit 6A, putative 0.0018 0.0021 0.0033
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0025 0.0138 0.0138
Toxoplasma gondii ABC1 family protein 0.0039 0.0409 0.0658
Loa Loa (eye worm) proteasome regulatory particle 0.0031 0.0257 0.0257
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0598 0.0773
Brugia malayi Trypsin family protein 0.0032 0.0278 0.0278
Onchocerca volvulus 0.0032 0.0278 0.136
Giardia lamblia 20S proteasome alpha subunit 4 0.0169 0.2792 0.449
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0032 0.0278 0.0359
Loa Loa (eye worm) hypothetical protein 0.0031 0.0252 0.0252
Brugia malayi PCI domain containing protein 0.0028 0.0204 0.0204
Plasmodium vivax 26S protease regulatory subunit 6a, putative 0.0018 0.0021 0.0033
Trypanosoma brucei trypanothione reductase 0.0041 0.0446 0.0714
Echinococcus multilocularis proteasome subunit beta type 7 0.0439 0.7733 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0278 0.0278
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0128 0.2043 0.3286
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0169 0.2792 0.3611
Toxoplasma gondii thioredoxin reductase 0.0041 0.0446 0.0717
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0018 0.002 0.0029
Brugia malayi Proteasome/cyclosome repeat family protein 0.0027 0.0189 0.0189
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0081 0.117 0.1513
Brugia malayi Proteasome/cyclosome repeat family protein 0.0027 0.0189 0.0189
Plasmodium falciparum proteasome subunit beta type-5 0.0356 0.6217 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0182 0.0235
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0356 0.6217 1
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0138 0.2211 0.3557
Onchocerca volvulus 0.0039 0.0409 0.2002
Giardia lamblia 26S proteasome regulatory subunit, putative 0.0019 0.004 0.0061
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.0026 0.016 0.0256
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0409 0.0655
Brugia malayi glutathione reductase 0.0041 0.0446 0.0446
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0146 0.236 0.3795
Giardia lamblia Proteasome subunit beta type 1 0.0146 0.236 0.3794
Loa Loa (eye worm) hypothetical protein 0.0031 0.025 0.025
Echinococcus granulosus nuclear factor of activated T cells 5 0.0301 0.5209 0.6736
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0095 0.1419 0.174
Loa Loa (eye worm) 26S protease regulatory subunit 6A 0.0018 0.0021 0.0021
Schistosoma mansoni 26S protease regulatory subunit 0.0017 0.0002 0.0002
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.0031 0.0257 0.0414
Leishmania major proteasome alpha 1 subunit, putative 0.0127 0.201 0.3232
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0138 0.2211 0.3557
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0182 0.0182
Echinococcus multilocularis 26S proteasome regulatory subunit T3 0.0017 0.0002 0.0002
Trichomonas vaginalis proteasome regulatory subunits, putative 0.0028 0.0204 0.0326
Loa Loa (eye worm) PCI domain-containing protein 0.0026 0.016 0.016
Echinococcus multilocularis glycoprotein Antigen 5 0.0032 0.0278 0.0359
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0356 0.6217 0.6217
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0137 0.2196 0.3533
Loa Loa (eye worm) hypothetical protein 0.0032 0.0278 0.0278
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0127 0.2017 0.2609
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0018 0.0021 0.0027
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0025 0.0138 0.0138
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0182 0.0235
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0356 0.6217 1
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.0037 0.0366 0.0473
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0182 0.0182
Brugia malayi proteasome subunit alpha type 1 0.0127 0.201 0.201
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0122 0.1926 0.2491
Echinococcus granulosus proteasome subunit beta t family 0.0122 0.1926 0.2491
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.0000099825 0.0000099825
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0135 0.217 0.217
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.0028 0.0203 0.0326
Plasmodium vivax proteasome subunit beta type-3, putative 0.0122 0.1926 0.3099
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0099 0.1509 0.2425
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0122 0.1926 0.3099
Brugia malayi Steroid receptor seven-up type 2 0.0027 0.0182 0.0182
Plasmodium falciparum 26S protease regulatory subunit 6B, putative 0.0017 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0278 0.0278
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.0026 0.016 0.0254
Plasmodium vivax proteasome subunit beta type-5, putative 0.0356 0.6217 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0027 0.0182 0.0182
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0037 0.0366 0.0473
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0409 0.0409
Leishmania major proteasome alpha 1 subunit, putative 0.0138 0.2211 0.3557
Giardia lamblia Hypothetical protein 0.0031 0.0257 0.0411
Trypanosoma brucei proteasome beta 7 subunit 0.0121 0.19 0.3054
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0169 0.2792 0.2792
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0027 0.0182 0.0235
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0169 0.2792 0.449
Entamoeba histolytica 19S cap proteasome S2 subunit 0.0018 0.0011 0.0015
Plasmodium falciparum thioredoxin reductase 0.0041 0.0446 0.0717
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0026 0.0162 0.026
Plasmodium vivax 26S protease regulatory subunit 4, putative 0.0017 0.0002 0.0003
Loa Loa (eye worm) PCI domain-containing protein 0.0028 0.0204 0.0204
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0032 0.0278 0.0278
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0027 0.0182 0.0182
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0598 0.0773
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.0031 0.0257 0.0414
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0121 0.19 0.3054
Brugia malayi hypothetical protein 0.0032 0.0278 0.0278
Plasmodium falciparum glutathione reductase 0.0041 0.0446 0.0717
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0146 0.2358 0.3793
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0127 0.2024 0.3256
Toxoplasma gondii PCI domain-containing protein 0.0031 0.0257 0.0414
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0598 0.0773
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0121 0.19 0.3056
Loa Loa (eye worm) hypothetical protein 0.0039 0.0409 0.0409
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0026 0.0162 0.0162
Brugia malayi proteasome subunit beta type 2 0.0122 0.1926 0.1926
Echinococcus granulosus proteasome 26s subunit subunit 4 atpase 0.0017 0.0002 0.0002
Giardia lamblia 20S proteasome alpha subunit 1 0.0138 0.2211 0.3555
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0025 0.0146 0.0235
Entamoeba histolytica proteasome regulatory subunit, putative 0.0025 0.0138 0.0219
Loa Loa (eye worm) hypothetical protein 0.0081 0.117 0.117
Toxoplasma gondii proteasome beta subunit 0.0122 0.1926 0.3099
Loa Loa (eye worm) hypothetical protein 0.0032 0.0278 0.0278
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0146 0.236 0.3051
Brugia malayi Proteasome subunit alpha type 7-1 0.0169 0.2792 0.2792
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0027 0.0182 0.0235
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0027 0.0182 0.0182
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.0037 0.0366 0.0366
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.0026 0.0162 0.0209
Giardia lamblia 20S proteasome alpha subunit 3 0.0127 0.2017 0.3243
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0356 0.6217 1
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.0026 0.016 0.0256
Mycobacterium tuberculosis Probable reductase 0.0095 0.1419 0.174
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0027 0.0182 0.0235
Onchocerca volvulus Bile acid receptor homolog 0.0027 0.0182 0.0889
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0182 0.0182
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0027 0.0182 0.0235
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0018 0.0021 0.0031
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0135 0.217 0.3489
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0146 0.2358 0.305
Leishmania major proteasome regulatory ATPase subunit 2, putative 0.0017 0.0002 0.0003
Trichomonas vaginalis 26S proteasome regulatory subunit S3, putative 0.0018 0.002 0.003
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0027 0.0182 0.0182
Echinococcus granulosus proteasome prosome macropain 0.0356 0.6217 0.804
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0025 0.0138 0.0219
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0146 0.236 0.3794
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0037 0.0366 0.0585
Leishmania major proteasome beta 2 subunit, putative 0.0122 0.1926 0.3099
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0026 0.0162 0.0209
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0409 0.0655
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0122 0.1926 0.2491
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.0028 0.0204 0.0329
Toxoplasma gondii proteasome subunit beta type, putative 0.0356 0.6217 1
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0017 0.0002 0.0003
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0137 0.2196 0.3533
Echinococcus granulosus FTZ F1 alpha 0.0027 0.0182 0.0235
Schistosoma mansoni cercarial elastase (S01 family) 0.0032 0.0278 0.0359
Brugia malayi Probable 26S protease regulatory subunit 4 0.0017 0.0002 0.0002
Schistosoma mansoni carbonic anhydrase-related 0.0054 0.0678 0.0877
Echinococcus granulosus Mastin 0.0032 0.0278 0.0359
Entamoeba histolytica proteasome regulatory subunit, putative 0.0028 0.0204 0.0326
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0135 0.217 0.3491
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.0031 0.0257 0.0257
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0137 0.2196 0.284
Schistosoma mansoni carbonic anhydrase-related 0.0054 0.0678 0.0877
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0027 0.0182 0.0182
Echinococcus granulosus thioredoxin glutathione reductase 0.0042 0.0456 0.0589
Loa Loa (eye worm) hypothetical protein 0.0023 0.0103 0.0103
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0409 0.0529
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0033 0.0291 0.0376
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0182 0.0235
Mycobacterium tuberculosis Probable oxidoreductase 0.0105 0.1613 0.2073
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0128 0.2043 0.3284
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0121 0.19 0.3056
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0026 0.0162 0.0258
Leishmania major hypothetical protein, conserved 0.0042 0.0459 0.0738
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0146 0.2358 0.2358
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.0026 0.0162 0.026
Echinococcus multilocularis enteropeptidase 0.0032 0.0278 0.0359
Giardia lamblia Proteasome subunit beta type 3 0.0122 0.1926 0.3097
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0122 0.1926 0.3097
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.0033 0.0291 0.0376
Onchocerca volvulus 0.0017 0.0002 0.0009
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0025 0.0138 0.0219
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0356 0.6217 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0122 0.1926 0.3097
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.0031 0.0257 0.0411
Schistosoma mansoni cercarial elastase (S01 family) 0.0032 0.0278 0.0359
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0032 0.0278 0.0359
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0017 0.0002 0.0003
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0356 0.6217 1
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0026 0.0162 0.026
Brugia malayi proteasome subunit beta type 1 0.0146 0.236 0.236
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0184 0.3061 0.3061
Echinococcus multilocularis thioredoxin glutathione reductase 0.0042 0.0456 0.0589
Toxoplasma gondii heat shock protein hslv, putative 0.0099 0.1509 0.2427
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0169 0.2792 0.449
Brugia malayi Trypsin family protein 0.0032 0.0278 0.0278
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0127 0.201 0.3232
Loa Loa (eye worm) proteasome subunit beta type 3 0.0122 0.1926 0.1926
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0127 0.201 0.3232
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.0026 0.0162 0.0162
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0026 0.0162 0.0258
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.025 0.025
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0137 0.2196 0.284
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0054 0.0678 0.0678
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0127 0.2017 0.3243
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0127 0.2017 0.3245
Loa Loa (eye worm) hypothetical protein 0.0027 0.0182 0.0182
Echinococcus multilocularis thyroid hormone receptor alpha 0.0027 0.0182 0.0235
Schistosoma mansoni cercarial elastase (S01 family) 0.0032 0.0278 0.0359
Loa Loa (eye worm) hypothetical protein 0.0027 0.0182 0.0182
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0033 0.0291 0.0376
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0146 0.236 0.3794
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0409 0.0655
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0027 0.0182 0.0235
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.0028 0.0203 0.0326
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0099 0.1509 0.2425
Onchocerca volvulus 0.0032 0.0278 0.136
Mycobacterium ulcerans beta-lactamase 0.0039 0.0409 0.0221
Trichomonas vaginalis esterase, putative 0.0039 0.0409 0.0655
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0025 0.0138 0.0222
Leishmania major trypanothione reductase 0.0041 0.0446 0.0717
Echinococcus granulosus death domain containing protein 0.0031 0.025 0.0324
Schistosoma mansoni 26S protease regulatory subunit 6b 0.0017 0.0002 0.0002
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0169 0.2792 0.3611
Brugia malayi Death domain containing protein 0.0031 0.025 0.025
Plasmodium falciparum 26S protease regulatory subunit 4, putative 0.0017 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0182 0.0182
Toxoplasma gondii proteasome subunit alpha type, putative 0.007 0.0969 0.1558
Echinococcus granulosus transmembrane protease serine 3 0.0032 0.0278 0.0359
Loa Loa (eye worm) hypothetical protein 0.0039 0.0409 0.0409
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0025 0.0138 0.0222
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0122 0.1926 0.3099
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0127 0.2017 0.3245
Loa Loa (eye worm) hypothetical protein 0.0032 0.0278 0.0278
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0032 0.0278 0.0359
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0095 0.1419 0.174
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0135 0.217 0.3489
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0027 0.0182 0.0182
Echinococcus multilocularis 26s protease regulatory subunit 6a 0.0018 0.0021 0.0027
Brugia malayi photoreceptor-specific nuclear receptor 0.0027 0.0182 0.0182
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.0026 0.0162 0.0162
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0031 0.0257 0.0333
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0026 0.0162 0.0209
Giardia lamblia 20S proteasome alpha subunit 2 0.0131 0.2096 0.3369
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0054 0.0678 0.0678
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0409 0.0658
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0121 0.19 0.2457
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.068 0.068
Echinococcus granulosus glycoprotein Antigen 5 0.0032 0.0278 0.0359
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0031 0.0257 0.0333
Loa Loa (eye worm) proteasome subunit beta type 2 0.0122 0.1926 0.1926
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0018 0.0021 0.0033
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0026 0.0162 0.026
Schistosoma mansoni retinoic acid receptor RXR 0.0027 0.0182 0.0235
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0027 0.0182 0.0235
Plasmodium vivax proteasome subunit beta type-6, putative 0.0127 0.2024 0.3256
Onchocerca volvulus 0.0032 0.0278 0.136
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.0033 0.0291 0.0468
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0032 0.0278 0.0359
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0099 0.1509 0.1894
Loa Loa (eye worm) RPN-3 protein 0.0034 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0562 1 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0182 0.0182
Plasmodium falciparum proteasome subunit beta type-4 0.0121 0.19 0.3056
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0027 0.0182 0.0235
Loa Loa (eye worm) steroid hormone receptor 0.0027 0.0182 0.0182
Brugia malayi Thioredoxin reductase 0.0041 0.0446 0.0446
Echinococcus multilocularis proteasome subunit beta type 6 0.0127 0.2024 0.2618
Echinococcus multilocularis adhesion regulating molecule 1 0.0081 0.117 0.1513
Entamoeba histolytica hypothetical protein 0.0035 0.0328 0.0525
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0122 0.1926 0.2491
Schistosoma mansoni hypothetical protein 0.0165 0.2711 0.3506
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.0034 0.03 0.0483
Onchocerca volvulus 0.0032 0.0278 0.136
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0028 0.0203 0.0326
Brugia malayi Kringle domain containing protein 0.0017 0.0000099825 0.0000099825
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0027 0.0182 0.0182
Mycobacterium ulcerans proteasome PrcA 0.0099 0.1509 0.2073
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0127 0.2017 0.3243
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0117 0.184 0.296
Schistosoma mansoni hypothetical protein 0.0035 0.0328 0.0424
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0409 0.0655
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.0026 0.0162 0.026
Brugia malayi beta-lactamase family protein 0.0039 0.0409 0.0409
Loa Loa (eye worm) carbonic anhydrase 3 0.0146 0.2358 0.2358
Leishmania major proteasome beta 2 subunit, putative 0.0135 0.217 0.3491
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0409 0.0658
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0027 0.0182 0.0235
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0131 0.2096 0.3371
Echinococcus multilocularis proteasome subunit alpha type 2 0.0131 0.2096 0.271
Loa Loa (eye worm) hypothetical protein 0.0039 0.0409 0.0409
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0027 0.0182 0.0235
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0252 0.4308 0.6713
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.0075 0.1061 0.1371
Entamoeba histolytica proteasome regulatory subunit, putative 0.0031 0.0257 0.0411
Brugia malayi 26S proteasome regulatory complex subunit p97 0.0037 0.0366 0.0366
Loa Loa (eye worm) thioredoxin reductase 0.0041 0.0446 0.0446
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0127 0.201 0.323
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0027 0.0189 0.0302
Brugia malayi proteasome subunit alpha type 2 0.0131 0.2096 0.2096
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.068 0.068
Toxoplasma gondii proteasome 26S regulatory subunit 0.0018 0.0011 0.0018
Toxoplasma gondii proteasome subunit alpha type, putative 0.0127 0.2017 0.3245
Schistosoma mansoni 26s proteasome non-ATPase regulatory subunit 4 0.0018 0.002 0.0026
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0025 0.0138 0.0219
Onchocerca volvulus Protein ultraspiracle homolog 0.0027 0.0182 0.0889
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0409 0.0529
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0122 0.1926 0.2491
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0146 0.2358 0.305
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0026 0.0162 0.0162
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0127 0.2024 0.3254
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0027 0.0182 0.0182
Onchocerca volvulus 0.0017 0.0002 0.0009
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0121 0.19 0.19
Entamoeba histolytica hypothetical protein 0.0035 0.0328 0.0525
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0127 0.201 0.2599
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0128 0.2043 0.3286
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0018 0.0021 0.0027
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.0037 0.0366 0.0585
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0598 0.0773
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.0028 0.0203 0.0262
Loa Loa (eye worm) hypothetical protein 0.0027 0.0182 0.0182
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0127 0.201 0.201
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0409 0.0658
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0122 0.1926 0.3099
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0127 0.2024 0.3256
Schistosoma mansoni RAR-like nuclear receptor 0.0027 0.0182 0.0235
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0182 0.0182
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0117 0.184 0.2958
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.0033 0.0291 0.0468
Brugia malayi nuclear hormone receptor 0.0027 0.0182 0.0182
Brugia malayi Trypsin family protein 0.0032 0.0278 0.0278
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0137 0.2196 0.3533
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0127 0.2017 0.3245
Brugia malayi 26S proteasome subunit P45 family protein 0.0017 0.0002 0.0002
Giardia lamblia Proteasome subunit beta type 2 0.0122 0.1926 0.3097
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0032 0.0278 0.0359
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 4 0.0018 0.002 0.0026
Echinococcus granulosus geminin 0.0165 0.2711 0.3506
Loa Loa (eye worm) RPT-2 protein 0.0017 0.0002 0.0002
Brugia malayi nuclear receptor NHR-88 0.0027 0.0182 0.0182
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0146 0.2358 0.2358
Plasmodium vivax proteasome subunit beta type-4, putative 0.0121 0.19 0.3056
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0169 0.2792 0.4491
Echinococcus multilocularis proteasome subunit alpha type 6 0.0138 0.2211 0.286
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0127 0.201 0.323
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0031 0.025 0.0324
Mycobacterium ulcerans hypothetical protein 0.0039 0.0409 0.0221
Echinococcus multilocularis geminin 0.0165 0.2711 0.3506
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0328 0.0424
Echinococcus granulosus carbonic anhydrase 0.0054 0.0678 0.0877
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0146 0.2358 0.3793
Onchocerca volvulus Netrin receptor homolog 0.0031 0.025 0.1225
Echinococcus granulosus proteasome subunit alpha type 2 0.0131 0.2096 0.271
Brugia malayi Protein kinase domain containing protein 0.0017 0.0000099825 0.0000099825
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.0028 0.0204 0.0326
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0099 0.1509 0.2427
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0169 0.2792 0.4491
Brugia malayi Proteasome subunit alpha type 1 0.0113 0.1754 0.1754
Leishmania major proteasome beta 5 subunit, putative 0.0356 0.6217 1
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0051 0.0628 0.3074
Leishmania major proteasome regulatory ATPase subunit 5, putative 0.0018 0.0021 0.0033
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0598 0.0598
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0121 0.19 0.3056
Echinococcus granulosus carbonic anhydrase II 0.0146 0.2358 0.305
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0169 0.2792 0.3611
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0026 0.0162 0.026
Brugia malayi steroid hormone receptor 0.0027 0.0182 0.0182
Echinococcus granulosus carbonic anhydrase 0.0054 0.0678 0.0877
Schistosoma mansoni hypothetical protein 0.005 0.0609 0.0788
Echinococcus granulosus enteropeptidase 0.0032 0.0278 0.0359
Giardia lamblia 26S protease regulatory subunit 6A 0.0018 0.0021 0.0031
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0128 0.2043 0.3286
Toxoplasma gondii proteasome regulatory subunit 0.0026 0.0162 0.026

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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