Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Ovis aries | Cyclooxygenase-1 | Starlite/ChEMBL | References |
Ovis aries | Cyclooxygenase-2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0489 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0489 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0489 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0489 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Toxoplasma gondii | melibiase subfamily protein | 0.0104 | 0.1296 | 0.5 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0069 | 0.0516 | 0.5 |
Echinococcus granulosus | peroxidasin | 0.0489 | 1 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.0489 | 1 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0489 | 1 | 0.5 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.0104 | 0.1296 | 0.1296 |
Onchocerca volvulus | 0.0489 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0489 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.0104 | 0.1296 | 0.1296 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0489 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0489 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0104 | 0.1296 | 0.1296 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0069 | 0.0516 | 0.0516 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0104 | 0.1296 | 0.1296 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0104 | 0.1296 | 0.1296 |
Onchocerca volvulus | 0.0489 | 1 | 0.5 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0489 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0489 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0489 | 1 | 1 |
Echinococcus granulosus | Alpha N acetylgalactosaminidase | 0.0104 | 0.1296 | 0.1296 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0516 | 0.0516 |
Onchocerca volvulus | 0.0489 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0489 | 1 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0489 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0489 | 1 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0489 | 1 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0489 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0069 | 0.0516 | 0.0516 |
Brugia malayi | Animal haem peroxidase family protein | 0.0489 | 1 | 1 |
Brugia malayi | Peroxidasin | 0.0489 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0104 | 0.1296 | 0.1296 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0489 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0489 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0489 | 1 | 1 |
Brugia malayi | Melibiase family protein | 0.0069 | 0.0516 | 0.0516 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.