Detailed information for compound 1021562

Basic information

Technical information
  • TDR Targets ID: 1021562
  • Name: 1817-67-0
  • MW: 212.287 | Formula: C15H16O
  • H donors: 1 H acceptors: 1 LogP: 4.18 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(c(c1)C(c1ccccc1)C)O
  • InChi: 1S/C15H16O/c1-11-8-9-15(16)14(10-11)12(2)13-6-4-3-5-7-13/h3-10,12,16H,1-2H3
  • InChiKey: DJRYJQNZAYJVGF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(.alpha.-Methylbenzyl)-p-cresol
  • 2-(alpha-Methylbenzyl)-4-methylphenol
  • 4-METHYL-2-(1-PHENYLETHYL)PHENOL
  • NSC 1770
  • NSC1770
  • Phenol, 2-(alpha-methylbenzyl)-4-methyl-
  • Phenol, 4-methyl-2-(1-phenylethyl)-
  • SL8800000
  • ST5444622

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.2087 0.2048
Onchocerca volvulus 0.0094 0.1128 0.2835
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0523 0.1581
Plasmodium vivax vivapain-3 0.0019 0.0076 0.0091
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0515 0.0468
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0219 0.2885 0.3144
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0317 0.0957
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0733 0.0687
Brugia malayi MH1 domain containing protein 0.0017 0.0049 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1763 1
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0187 0.0138
Entamoeba histolytica hypothetical protein 0.0051 0.0523 0.3607
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0849 0.385
Leishmania major cathepsin L-like protease 0.0139 0.1763 1
Schistosoma mansoni alpha glucosidase 0.0036 0.0317 0.0269
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.2087 0.2048
Loa Loa (eye worm) hypothetical protein 0.0074 0.0849 0.0925
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0849 0.2564
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0324 0.0276
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0523 0.1581
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0086 0.0488
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0668 0.9176 1
Onchocerca volvulus Cathepsin F homolog 0.0037 0.0324 0.0815
Onchocerca volvulus Huntingtin homolog 0.0137 0.173 0.4349
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0116 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0086 0.0488
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0324 0.0979
Trichomonas vaginalis importin beta-1, putative 0.0051 0.0523 0.1581
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0117 0.1451 0.1408
Echinococcus granulosus cathepsin L cysteine protease 0.0019 0.0076 0.0027
Loa Loa (eye worm) hypothetical protein 0.0297 0.3978 0.4335
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0849 0.0803
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0027 0.0187 0.1288
Echinococcus granulosus cathepsin L cysteine proteinase 0.0037 0.0324 0.0276
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0161 0.2066 1
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0058 0.0008
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0324 0.0815
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0027 0.0187 0.0138
Trypanosoma cruzi cysteine peptidase, putative 0.0139 0.1763 1
Toxoplasma gondii HEAT repeat-containing protein 0.0063 0.0689 0.3144
Loa Loa (eye worm) hypothetical protein 0.0074 0.0849 0.0925
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1763 1
Onchocerca volvulus 0.0037 0.0324 0.0815
Trypanosoma cruzi cysteine proteinase, putative 0.0019 0.0076 0.043
Loa Loa (eye worm) hypothetical protein 0.0137 0.173 0.1885
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0058 0.0326
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0116 0.0656
Echinococcus granulosus dna polymerase eta 0.0045 0.0448 0.0401
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0515 0.0468
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0382 0.0962
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1763 1
Leishmania major cysteine peptidase A (CPA) 0.0037 0.0324 0.1838
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0116 0.0047
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0116 0.029
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0127 0.1594 0.904
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Loa Loa (eye worm) TAR-binding protein 0.0195 0.2544 0.2772
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0027 0.0187 0.0644
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0161 0.2066 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0324 0.0979
Leishmania major cathepsin L-like protease 0.0139 0.1763 1
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0058 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0086 0.0488
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0324 0.0979
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0116 0.015
Brugia malayi Cathepsin L-like precursor 0.0037 0.0324 0.0815
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0207 0.0742
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0317 0.0957
Onchocerca volvulus 0.0074 0.0849 0.2133
Toxoplasma gondii ABC1 family protein 0.0074 0.0849 0.3938
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0324 0.0979
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1763 1
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0161 0.2066 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1763 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0515 0.0468
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0116 0.0656
Entamoeba histolytica cysteine proteinase 2 0.0019 0.0076 0.0522
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0076 0.019
Echinococcus multilocularis GPCR, family 2 0.0068 0.076 0.0714
Trypanosoma cruzi cysteine protease, putative 0.0019 0.0076 0.043
Trypanosoma brucei glucosidase, putative 0.0036 0.0317 0.1797
Echinococcus granulosus tumor protein p63 0.0679 0.9329 0.9326
Schistosoma mansoni hypothetical protein 0.0068 0.076 0.0714
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0155 0.1067
Loa Loa (eye worm) hypothetical protein 0.0137 0.173 0.1885
Leishmania major cathepsin L-like protease 0.0037 0.0324 0.1838
Schistosoma mansoni hypothetical protein 0.0068 0.076 0.0714
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0049 0.0054
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0155 0.0106
Echinococcus granulosus snurportin 1 0.0668 0.9176 0.9172
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1763 1
Echinococcus multilocularis importin subunit beta 1 0.0063 0.0689 0.0643
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0161 0.2066 1
Brugia malayi hypothetical protein 0.0297 0.3978 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0733 0.0799
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0849 0.0925
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1763 1
Echinococcus multilocularis geminin 0.0361 0.4872 0.4847
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0086 0.0037
Loa Loa (eye worm) TK/ABL protein kinase 0.024 0.3176 0.3461
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0849 0.2564
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0019 0.0076 0.043
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0086 0.0216
Brugia malayi beta-lactamase family protein 0.0074 0.0849 0.2133
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0086 0.0488
Brugia malayi hypothetical protein 0.0117 0.1451 0.3647
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0317 0.0269
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0382 0.2636
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0037 0.0324 0.0353
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0849 0.0803
Echinococcus granulosus peptidase Clp S14 family 0.0105 0.129 0.1247
Loa Loa (eye worm) hypothetical protein 0.0214 0.2807 0.306
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0086 0.0488
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0382 0.0335
Echinococcus granulosus cathepsin l cysteine peptidase 0.0037 0.0324 0.0276
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0382 0.0335
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0317 0.0796
Brugia malayi Tyrosine-protein kinase abl-1 0.0098 0.1183 0.2975
Schistosoma mansoni microtubule-associated protein tau 0.0727 1 1
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0055 0.0589 0.2644
Schistosoma mansoni ap endonuclease 0.0022 0.0116 0.0067
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0849 0.4813
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0037 0.0324 0.0353
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0382 0.0335
Toxoplasma gondii cathepsin CPL 0.0037 0.0324 0.1327
Brugia malayi jmjC domain containing protein 0.0066 0.0733 0.1842
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Brugia malayi RNA recognition motif domain containing protein 0.0195 0.2544 0.6395
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.076 0.191
Onchocerca volvulus 0.0099 0.1205 0.3029
Schistosoma mansoni hypothetical protein 0.0068 0.076 0.0714
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0324 0.0979
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0027 0.0187 0.106
Brugia malayi Pre-SET motif family protein 0.0219 0.2885 0.7252
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0448 0.2541
Onchocerca volvulus 0.0037 0.0324 0.0815
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0207 0.1172
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0027 0.0187 0.0138
Schistosoma mansoni alpha-glucosidase 0.014 0.177 0.173
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0849 0.2133
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0086 0.0594
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0105 0.129 0.4744
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0324 0.0276
Schistosoma mansoni ap endonuclease 0.0022 0.0116 0.0067
Loa Loa (eye worm) hypothetical protein 0.0045 0.0448 0.0488
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0058 0.0008
Brugia malayi cathepsin L-like precursor 0.0024 0.0155 0.0389
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0253 0.0205
Brugia malayi Cathepsin L-like precursor 0.0024 0.0155 0.0389
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0058 0.0008
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0116 0.0067
Onchocerca volvulus 0.0037 0.0324 0.0815
Brugia malayi latrophilin 2 splice variant baaae 0.0146 0.186 0.4675
Trypanosoma brucei importin beta-1 subunit, putative 0.0063 0.0689 0.3908
Echinococcus granulosus tyrosine protein kinase ABL1 0.024 0.3176 0.3142
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0849 0.3938
Brugia malayi jmjC domain containing protein 0.0018 0.0058 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1763 1
Leishmania major importin beta-1 subunit, putative 0.0051 0.0523 0.2967
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Echinococcus multilocularis microtubule associated protein 2 0.0727 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0086 0.0488
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0086 0.0488
Echinococcus multilocularis cathepsin L 0.0019 0.0076 0.0027
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0207 0.0742
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0058 0.0063
Brugia malayi MH2 domain containing protein 0.0017 0.0049 0.0124
Brugia malayi Cathepsin L-like precursor 0.0024 0.0155 0.0389
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0253 0.0972
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1763 1
Trichomonas vaginalis set domain proteins, putative 0.025 0.3309 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0207 0.0225
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.2087 0.5247
Plasmodium falciparum T-complex protein 1 subunit beta 0.0027 0.0187 0.0644
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0161 0.2066 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0086 0.0488
Leishmania major cathepsin L-like protease 0.0139 0.1763 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.1205 0.1313
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0515 0.0468
Onchocerca volvulus 0.0074 0.0849 0.2133
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0515 0.0561
Entamoeba histolytica hypothetical protein 0.0117 0.1451 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0161 0.2066 1
Schistosoma mansoni hypothetical protein 0.0068 0.076 0.0714
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0058 0.0008
Mycobacterium tuberculosis Conserved protein 0.0074 0.0849 0.1201
Trypanosoma cruzi cysteine peptidase, putative 0.0139 0.1763 1
Leishmania major cathepsin L-like protease 0.0037 0.0324 0.1838
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0058 0.0326
Echinococcus multilocularis dna polymerase kappa 0.002 0.0086 0.0037
Schistosoma mansoni hypothetical protein 0.0361 0.4872 0.4847
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0116 0.0126
Giardia lamblia TCP-1 chaperonin subunit beta 0.0027 0.0187 0.3401
Loa Loa (eye worm) hypothetical protein 0.0146 0.186 0.2027
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0207 0.0742
Schistosoma mansoni jumonji domain containing protein 0.0066 0.0733 0.0687
Loa Loa (eye worm) fibroinase 0.0037 0.0324 0.0353
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0086 0.0037
Leishmania major cathepsin L-like protease 0.0037 0.0324 0.1838
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0055 0.0589 0.2425
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0086 0.0094
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0086 0.0488
Loa Loa (eye worm) hypothetical protein 0.0074 0.0849 0.0925
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0259 0.1003
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0086 0.0488
Trypanosoma brucei unspecified product 0.0013 0.0001 0.0006
Onchocerca volvulus 0.025 0.3309 0.8319
Echinococcus granulosus geminin 0.0361 0.4872 0.4847
Toxoplasma gondii hypothetical protein 0.0055 0.0589 0.2644
Mycobacterium ulcerans beta-lactamase 0.0074 0.0849 0.385
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0382 0.0335
Brugia malayi Tyrosine-protein kinase abl-1 0.0146 0.1851 0.4654
Loa Loa (eye worm) hypothetical protein 0.0018 0.0058 0.0063
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0117 0.1451 0.1408
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0116 0.0798
Onchocerca volvulus 0.0297 0.3978 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.076 0.0828
Onchocerca volvulus 0.0024 0.0155 0.0389
Brugia malayi TAR-binding protein 0.0195 0.2544 0.6395
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1763 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0155 0.0169
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0324 0.0979
Plasmodium vivax SET domain protein, putative 0.0031 0.0253 0.0972
Brugia malayi Cathepsin L-like precursor 0.0037 0.0324 0.0815
Loa Loa (eye worm) hypothetical protein 0.0041 0.0382 0.0417
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0317 0.0957
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0253 0.0205
Brugia malayi jmjC domain containing protein 0.0018 0.0058 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0076 0.0027
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0076 0.0522
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.0324 0.0276
Leishmania major DNA polymerase eta, putative 0.0045 0.0448 0.2541
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.076 0.0714
Schistosoma mansoni tar DNA-binding protein 0.0195 0.2544 0.2507
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0259 0.1469
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0058 0.0008
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0236 0.0188
Schistosoma mansoni tar DNA-binding protein 0.0195 0.2544 0.2507
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0324 0.0276
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0317 0.0957
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0027 0.0187 0.106
Loa Loa (eye worm) hypothetical protein 0.0091 0.1088 0.1186
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Brugia malayi Pre-SET motif family protein 0.0031 0.0253 0.0635
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0076 0.0522
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0058 0.0063
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0317 0.2184
Schistosoma mansoni alpha-glucosidase 0.014 0.177 0.173
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0058 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0139 0.1763 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0051 0.0523 0.2967
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0161 0.2066 0.2027
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0187 0.0138
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0382 0.0335
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0076 0.043
Plasmodium falciparum importin beta, putative 0.0063 0.0689 0.3144
Echinococcus multilocularis tyrosine protein kinase Abl 0.0098 0.1183 0.114
Loa Loa (eye worm) hypothetical protein 0.0074 0.0849 0.0925
Loa Loa (eye worm) hypothetical protein 0.0018 0.0058 0.0063
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0317 0.1291
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0161 0.2066 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0253 0.0205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0253 0.0205
Brugia malayi jmjC domain containing protein 0.0018 0.0058 0.0145
Echinococcus granulosus phd:f box containing protein 0.0018 0.0058 0.0008
Brugia malayi beta-lactamase 0.0074 0.0849 0.2133
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0473 0.6435 1
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0161 0.2066 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0116 0.1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0155 0.0169
Echinococcus granulosus cysteine protease 0.0019 0.0076 0.0027
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0382 0.2169
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0317 0.0957
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.3293 0.3589
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Trichomonas vaginalis chaperonin, putative 0.0027 0.0187 0.0565
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0049 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.0076 0.043
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0161 0.2066 0.5
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0058 0.0063
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0001 0.0006
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0058 0.0326
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0155 0.0468
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0849 0.1201
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0066 0.0733 0.0687
Loa Loa (eye worm) hypothetical protein 0.0074 0.0849 0.0925
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0382 0.2169
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0027 0.0187 0.0565
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0086 0.0488
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Echinococcus granulosus GPCR family 2 0.0068 0.076 0.0714
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0849 0.2564
Loa Loa (eye worm) T-complex protein 1 0.0027 0.0187 0.0204
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0324 0.0979
Loa Loa (eye worm) beta-lactamase 0.0074 0.0849 0.0925
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0058 0.0008
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.076 0.0828
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0086 0.0488
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0324 0.0979
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0076 0.0522
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0116 0.035
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0317 0.2184
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0058 0.0008
Entamoeba histolytica hypothetical protein 0.0117 0.1451 1
Loa Loa (eye worm) RNA binding protein 0.0195 0.2544 0.2772
Leishmania major hypothetical protein, conserved 0.0074 0.0849 0.4813
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0324 0.0815
Schistosoma mansoni tar DNA-binding protein 0.0195 0.2544 0.2507
Leishmania major hypothetical protein, conserved 0.0028 0.0207 0.1172
Echinococcus multilocularis tumor protein p63 0.0679 0.9329 0.9326
Brugia malayi MH2 domain containing protein 0.0017 0.0049 0.0124
Leishmania major T-complex protein 1, beta subunit, putative 0.0027 0.0187 0.106
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0058 0.0008
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0058 0.0008
Echinococcus multilocularis cysteine protease 0.0037 0.0324 0.0276
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0076 0.0027
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.2087 0.2275
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0155 0.0389
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0214 0.2807 0.306
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0317 0.0957
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Brugia malayi Calcitonin receptor-like protein seb-1 0.0214 0.2807 0.7057
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0849 0.1759
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0849 0.0803
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0324 0.0979
Trypanosoma cruzi cruzipain precursor, putative 0.0139 0.1763 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0317 0.0957
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0037 0.0324 0.1327
Leishmania major DNA polymerase eta, putative 0.0032 0.0259 0.1469
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0195 0.2544 0.2772
Schistosoma mansoni tar DNA-binding protein 0.0195 0.2544 0.2507
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0849 0.1201
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0105 0.129 0.1896
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0382 0.1156
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.076 0.0714
Schistosoma mansoni hypothetical protein 0.0146 0.186 0.1819
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0207 0.1172
Mycobacterium tuberculosis Conserved protein 0.0074 0.0849 0.1201
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0086 0.0037
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0849 0.2564
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.076 0.0714
Echinococcus multilocularis lysine specific demethylase 5A 0.0066 0.0733 0.0687
Echinococcus multilocularis dna polymerase eta 0.0045 0.0448 0.0401
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0849 0.1201
Plasmodium vivax importin-beta 2, putative 0.0063 0.0689 0.3144
Entamoeba histolytica cysteine protease, putative 0.0037 0.0324 0.2234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0155 0.0468
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0324 0.0815
Loa Loa (eye worm) hypothetical protein 0.0063 0.0689 0.0751
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0214 0.2807 0.7057
Trypanosoma brucei DNA polymerase eta, putative 0.0045 0.0448 0.2541
Toxoplasma gondii exonuclease III APE 0.0022 0.0116 0.029
Loa Loa (eye worm) hypothetical protein 0.0024 0.0155 0.0169
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0849 0.4813
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Plasmodium vivax vivapain-1 0.0019 0.0076 0.0091
Echinococcus granulosus dna polymerase kappa 0.002 0.0086 0.0037
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0324 0.0276
Echinococcus multilocularis peptidase Clp (S14 family) 0.0105 0.129 0.1247
Brugia malayi hypothetical protein 0.0137 0.173 0.4349
Plasmodium vivax vivapain-2 0.0037 0.0324 0.1327
Leishmania major cathepsin L-like protease 0.0037 0.0324 0.1838
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0515 0.0468
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0116 0.0656
Entamoeba histolytica cysteine proteinase 1, putative 0.0019 0.0076 0.0522
Echinococcus granulosus cathepsin l1 0.0024 0.0155 0.0106
Leishmania major DNA polymerase kappa, putative 0.002 0.0086 0.0488
Echinococcus granulosus importin subunit beta 1 0.0063 0.0689 0.0643
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.3293 0.3589
Trypanosoma cruzi cysteine proteinase, putative 0.0019 0.0076 0.043
Brugia malayi beta-lactamase family protein 0.0074 0.0849 0.2133
Brugia malayi MH2 domain containing protein 0.0249 0.3293 0.8279
Onchocerca volvulus 0.0037 0.0324 0.0815
Brugia malayi hypothetical protein 0.0028 0.0207 0.0519
Plasmodium vivax unspecified product 0.0019 0.0076 0.0091
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0086 0.026
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0105 0.129 0.1896
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0849 0.1201
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0076 0.0522
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0086 0.0488
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0733 0.0687
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0058 0.0008
Echinococcus granulosus cathepsin l1 0.0037 0.0324 0.0276
Loa Loa (eye worm) cysteine protease 0.0037 0.0324 0.0353
Schistosoma mansoni peptidase Clp (S14 family) 0.0161 0.2066 0.2027
Leishmania major hypothetical protein, conserved 0.0018 0.0058 0.0326
Brugia malayi Smad1 0.0017 0.0049 0.0124
Trypanosoma brucei unspecified product 0.002 0.0086 0.0488
Brugia malayi Latrophilin receptor protein 2 0.0068 0.076 0.191
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0058 0.0008
Onchocerca volvulus 0.0037 0.0324 0.0815
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0086 0.026
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0515 0.0468
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0324 0.0979
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0849 0.385
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0037 0.0324 0.1327
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0317 0.0957
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0382 0.2169
Echinococcus multilocularis tyrosine protein kinase ABL1 0.024 0.3176 0.3142
Brugia malayi hypothetical protein 0.0018 0.0067 0.0168
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0317 0.0345
Toxoplasma gondii t-complex protein beta subunit 0.0027 0.0187 0.0644
Onchocerca volvulus 0.0037 0.0324 0.0815
Schistosoma mansoni tar DNA-binding protein 0.0195 0.2544 0.2507
Echinococcus granulosus cathepsin L 0.0019 0.0076 0.0027
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0317 0.0269
Schistosoma mansoni hypothetical protein 0.0361 0.4872 0.4847
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0849 0.1201
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0116 0.035
Plasmodium falciparum cysteine proteinase falcipain 1 0.0019 0.0076 0.0091
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0086 0.0488
Leishmania major cathepsin L-like protease 0.0037 0.0324 0.1838
Trypanosoma cruzi major cysteine proteinase, putative 0.0109 0.1346 0.7631
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0448 0.1126
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0161 0.2066 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0076 0.0229
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0207 0.0742
Brugia malayi Cathepsin L-like precursor 0.0037 0.0324 0.0815
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0382 0.1156
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0116 0.0291
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0733 0.0687
Trichomonas vaginalis esterase, putative 0.0074 0.0849 0.2564
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0076 0.043
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0055 0.0589 0.2644
Onchocerca volvulus 0.0031 0.0253 0.0635
Plasmodium falciparum cysteine proteinase falcipain 3 0.0037 0.0324 0.1327
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0086 0.0488
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0849 0.1201
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0324 0.2234
Entamoeba histolytica hypothetical protein 0.0117 0.1451 1
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0187 0.047
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0161 0.2066 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0086 0.0488
Loa Loa (eye worm) Smad1 0.0017 0.0049 0.0054
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.0076 0.0027
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0058 0.0008
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0086 0.0037
Brugia malayi RNA, U transporter 1 0.0178 0.2306 0.5798
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Onchocerca volvulus 0.0037 0.0324 0.0815
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0382 0.0335
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0382 1
Schistosoma mansoni hypothetical protein 0.0117 0.1451 0.1408
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1763 1
Brugia malayi RNA binding protein 0.0195 0.2544 0.6395
Schistosoma mansoni DNA polymerase eta 0.0045 0.0448 0.0401
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0207 0.1172
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0849 0.0803
Echinococcus multilocularis cysteine protease 0.0037 0.0324 0.0276
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0066 0.0733 0.0687
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0116 0.0656
Brugia malayi jmjC domain containing protein 0.0018 0.0058 0.0145
Brugia malayi Cathepsin L-like precursor 0.0037 0.0324 0.0815
Entamoeba histolytica cysteine protease, putative 0.0019 0.0076 0.0522
Onchocerca volvulus Huntingtin homolog 0.0137 0.173 0.4349
Schistosoma mansoni hypothetical protein 0.0668 0.9176 0.9172
Brugia malayi MH1 domain containing protein 0.0017 0.0049 0.0124
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0317 0.1797
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0849 0.4813
Mycobacterium ulcerans lipase LipD 0.0074 0.0849 0.385
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0317 0.0957
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0076 0.019
Mycobacterium leprae Probable lipase LipE 0.0074 0.0849 0.1759
Brugia malayi Probable ClpP-like protease 0.0161 0.2066 0.5195
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0324 0.2234
Brugia malayi Cathepsin L-like precursor 0.0037 0.0324 0.0815
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0187 0.0138
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0515 0.1295
Echinococcus multilocularis snurportin 1 0.0668 0.9176 0.9172
Brugia malayi Importin beta-1 subunit 0.0063 0.0689 0.1732
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0849 0.2564
Echinococcus granulosus tar DNA binding protein 0.0195 0.2544 0.2507
Loa Loa (eye worm) hypothetical protein 0.0018 0.0058 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0161 0.2066 0.2027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0253 0.0205
Loa Loa (eye worm) hypothetical protein 0.0037 0.0324 0.0353
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0001 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0324 0.0979
Loa Loa (eye worm) hypothetical protein 0.0031 0.0253 0.0275
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0515 0.0468
Trypanosoma brucei unspecified product 0.0013 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0161 0.2066 0.2252
Loa Loa (eye worm) hypothetical protein 0.0074 0.0849 0.0925
Schistosoma mansoni transcription factor LCR-F1 0.0117 0.1451 0.1408
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0253 0.0205
Schistosoma mansoni tyrosine kinase 0.0237 0.3127 0.3094
Schistosoma mansoni importin beta-1 0.0063 0.0689 0.0643
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0086 0.0488
Echinococcus multilocularis tar DNA binding protein 0.0195 0.2544 0.2507
Trypanosoma brucei importin beta-1 subunit, putative 0.0063 0.0689 0.3908
Brugia malayi jmjC domain containing protein 0.0066 0.0733 0.1842
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.076 0.0714
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0076 0.0229
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0324 0.1838
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0317 0.1797
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0001 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0324 0.0979
Brugia malayi Cathepsin L-like precursor 0.0037 0.0324 0.0815
Mycobacterium ulcerans hypothetical protein 0.0074 0.0849 0.385
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0382 0.0335
Onchocerca volvulus 0.0074 0.0849 0.2133
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0116 0.029
Schistosoma mansoni cellular tumor antigen P53 0.0099 0.1205 0.1162
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.2087 0.2048
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0382 0.0335
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0317 0.1797
Entamoeba histolytica hypothetical protein 0.0117 0.1451 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0382 0.1156
Loa Loa (eye worm) ctsf protein 0.0037 0.0324 0.0353
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.0324 0.0276
Mycobacterium tuberculosis Conserved protein 0.0074 0.0849 0.1201
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0849 0.1201
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0086 0.0488
Plasmodium vivax vivapain-2 0.0037 0.0324 0.1327
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0253 0.0205
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0382 0.2169
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0187 0.047

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.