Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.36 | 0.36 |
Leishmania major | basic transcription factor 3a, putative | 0.0041 | 0.3959 | 1 |
Loa Loa (eye worm) | ICD-1 protein | 0.0041 | 0.3959 | 0.3959 |
Brugia malayi | beta-NAC-like protein | 0.0041 | 0.3959 | 0.3959 |
Echinococcus multilocularis | transcription factor btf3 | 0.0041 | 0.3959 | 0.5 |
Echinococcus granulosus | transcription factor btf3 | 0.0041 | 0.3959 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 1 | 1 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0041 | 0.3959 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.3959 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.3959 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.36 | 0.36 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0041 | 0.3959 | 1 |
Schistosoma mansoni | transcription factor btf3 | 0.0041 | 0.3959 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 1 | 1 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0041 | 0.3959 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.3959 | 0.5 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0041 | 0.3959 | 0.5 |
Toxoplasma gondii | NAC domain-containing protein | 0.0041 | 0.3959 | 1 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0041 | 0.3959 | 1 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0041 | 0.3959 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.3959 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.