Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Mus musculus | prostaglandin-endoperoxide synthase 2 | Starlite/ChEMBL | No references |
Homo sapiens | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0109 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.5 | 0.5 |
Schistosoma mansoni | transcription factor btf3 | 0.0109 | 0.5 | 0.5 |
Echinococcus granulosus | transcription factor btf3 | 0.0109 | 0.5 | 0.5 |
Echinococcus multilocularis | transcription factor btf3 | 0.0109 | 0.5 | 0.5 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0109 | 0.5 | 0.5 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0109 | 0.5 | 0.5 |
Loa Loa (eye worm) | ICD-1 protein | 0.0109 | 0.5 | 0.5 |
Leishmania major | basic transcription factor 3a, putative | 0.0109 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0109 | 0.5 | 0.5 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0109 | 0.5 | 0.5 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0109 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0109 | 0.5 | 0.5 |
Toxoplasma gondii | NAC domain-containing protein | 0.0109 | 0.5 | 0.5 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0109 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.