Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.0959 | 0.1588 |
Mycobacterium ulcerans | beta-lactamase | 0.0077 | 0.1419 | 0.2045 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0077 | 0.1419 | 0.4697 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0047 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1419 | 0.235 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0077 | 0.1419 | 0.235 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0027 | 0.0392 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0047 | 0.0078 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0077 | 0.1419 | 0.1235 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.018 | 0.3554 | 0.3416 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0047 | 0.0078 |
Plasmodium falciparum | glutathione reductase | 0.0027 | 0.0392 | 0.1312 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0047 | 0.0078 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.018 | 0.3554 | 0.3416 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0047 | 0.0155 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0443 | 0.0733 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0047 | 0.0078 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0047 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0047 | 0.0078 |
Brugia malayi | glutathione reductase | 0.0079 | 0.146 | 0.2419 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0077 | 0.1419 | 0.2045 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0047 | 0.0155 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0443 | 0.1466 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1419 | 0.235 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0027 | 0.0392 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0047 | 0.0078 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0443 | 0.1466 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0047 | 0.0078 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0079 | 0.146 | 0.2419 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0027 | 0.0392 | 0.5 |
Trichomonas vaginalis | set domain proteins, putative | 0.026 | 0.5208 | 0.8531 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0504 | 0.167 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.002 | 0.0242 | 0.0401 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0443 | 0.0733 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0141 | 0.2754 | 0.4562 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0047 | 0.0078 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0185 | 0.0306 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0504 | 0.167 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0027 | 0.0392 | 0.065 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0368 | 0.0236 |
Echinococcus multilocularis | lamin | 0.003 | 0.0443 | 0.1466 |
Schistosoma mansoni | thyroid hormone receptor | 0.0144 | 0.2797 | 0.4633 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0443 | 0.1466 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0027 | 0.0392 | 0.1312 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0047 | 0.0078 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.0615 | 1 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0141 | 0.2754 | 0.4562 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0047 | 0.0078 |
Brugia malayi | MH2 domain containing protein | 0.0123 | 0.2377 | 0.3938 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1419 | 0.235 |
Plasmodium vivax | hypothetical protein, conserved | 0.0077 | 0.1419 | 0.9661 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0027 | 0.0392 | 0.1312 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.1419 | 0.1818 |
Onchocerca volvulus | 0.0033 | 0.0504 | 0.0886 | |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0185 | 0.0306 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.008 | 0.1482 | 0.4907 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.0368 | 0.0236 |
Loa Loa (eye worm) | glutaminase | 0.03 | 0.6037 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0368 | 0.0236 |
Treponema pallidum | NADH oxidase | 0.0027 | 0.0392 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1419 | 0.235 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0047 | 0.0078 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0077 | 0.1419 | 0.235 |
Mycobacterium leprae | Probable lipase LipE | 0.0077 | 0.1419 | 0.2917 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0431 | 0.0715 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0047 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0959 | 0.1588 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.1419 | 0.961 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0185 | 0.0611 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0479 | 0.1587 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0154 | 0.302 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0027 | 0.0392 | 0.1312 |
Entamoeba histolytica | hypothetical protein | 0.0154 | 0.302 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.1419 | 0.235 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0047 | 0.0078 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0133 | 0.2576 | 0.853 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.018 | 0.3554 | 0.3416 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0047 | 0.0078 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0047 | 0.0078 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0047 | 0.0078 |
Onchocerca volvulus | 0.003 | 0.0443 | 0.0767 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0047 | 0.0078 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.0368 | 0.0163 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.02 | 0.397 | 0.3841 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0047 | 0.0078 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.1419 | 0.1818 |
Loa Loa (eye worm) | beta-lactamase | 0.0077 | 0.1419 | 0.235 |
Onchocerca volvulus | 0.0077 | 0.1419 | 0.2658 | |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0047 | 0.0078 |
Leishmania major | hypothetical protein, conserved | 0.0077 | 0.1419 | 0.9619 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0383 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0228 | 0.4555 | 0.7545 |
Onchocerca volvulus | 0.026 | 0.5208 | 1 | |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0047 | 0.0078 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.018 | 0.3554 | 0.3416 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0504 | 0.0836 |
Onchocerca volvulus | 0.0026 | 0.0368 | 0.0622 | |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0047 | 0.0078 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0077 | 0.1419 | 0.1235 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.0959 | 0.1588 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0185 | 0.0306 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.02 | 0.397 | 0.3841 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0185 | 0.0611 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0016 | 0.0156 | 0.0259 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0047 | 0.0155 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0027 | 0.0392 | 0.0222 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0123 | 0.2377 | 0.3938 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0027 | 0.0392 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0077 | 0.1419 | 0.4697 |
Schistosoma mansoni | hypothetical protein | 0.0133 | 0.2576 | 0.4267 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0047 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0383 |
Toxoplasma gondii | ABC1 family protein | 0.0077 | 0.1419 | 0.961 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.1419 | 0.1818 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.1419 | 0.1235 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0047 | 0.0155 |
Plasmodium falciparum | thioredoxin reductase | 0.0079 | 0.146 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0042 | 0.0687 | 0.371 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0154 | 0.302 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0047 | 0.0078 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0077 | 0.1419 | 0.2045 |
Entamoeba histolytica | hypothetical protein | 0.0154 | 0.302 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0077 | 0.1419 | 0.2045 |
Brugia malayi | glutaminase DH11.1 | 0.03 | 0.6037 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0228 | 0.4555 | 0.7545 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.02 | 0.397 | 0.3841 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0047 | 0.0078 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.02 | 0.397 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.018 | 0.3554 | 0.3416 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0504 | 0.0836 |
Mycobacterium leprae | conserved hypothetical protein | 0.0077 | 0.1419 | 0.2917 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0047 | 0.0155 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0133 | 0.2576 | 0.853 |
Loa Loa (eye worm) | glutathione reductase | 0.0079 | 0.146 | 0.2419 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.0615 | 0.3126 |
Mycobacterium ulcerans | glutaminase | 0.03 | 0.6037 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0112 | 0.0186 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0077 | 0.1419 | 0.1235 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0042 | 0.0687 | 0.0522 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0047 | 0.0155 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0368 | 0.061 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0443 | 0.0733 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0014 | 0.0124 | 0.041 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1419 | 0.235 |
Schistosoma mansoni | lamin | 0.003 | 0.0443 | 0.0733 |
Loa Loa (eye worm) | acetyltransferase | 0.0141 | 0.2754 | 0.4562 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0047 | 0.0155 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.008 | 0.1482 | 0.4907 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0504 | 0.0836 |
Trichomonas vaginalis | glutaminase, putative | 0.03 | 0.6037 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.0368 | 0.0236 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.1419 | 0.235 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0504 | 0.0836 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0368 | 0.061 |
Onchocerca volvulus | 0.0077 | 0.1419 | 0.2658 | |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0077 | 0.1419 | 0.1235 |
Toxoplasma gondii | thioredoxin reductase | 0.0079 | 0.146 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.1419 | 0.235 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0047 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0383 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0185 | 0.0306 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0042 | 0.0687 | 0.2275 |
Mycobacterium ulcerans | hypothetical protein | 0.0077 | 0.1419 | 0.2045 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0144 | 0.2797 | 0.9261 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0042 | 0.0687 | 0.2759 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0027 | 0.0392 | 0.065 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0124 | 0.0205 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0368 | 0.0236 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0027 | 0.0392 | 0.1299 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0185 | 0.0306 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.0368 | 0.0236 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0154 | 0.302 | 0.5003 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0443 | 0.0733 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0014 | 0.0124 | 0.041 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0047 | 0.0155 |
Schistosoma mansoni | lamin | 0.003 | 0.0443 | 0.0733 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0141 | 0.2754 | 0.9118 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0047 | 0.0155 |
Brugia malayi | Thioredoxin reductase | 0.0079 | 0.146 | 0.2419 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0047 | 0.0078 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0027 | 0.0392 | 0.0222 |
Plasmodium falciparum | glutathione reductase | 0.0079 | 0.146 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0383 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0077 | 0.1419 | 0.961 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0504 | 0.1048 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.0615 | 0.0932 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0504 | 0.0836 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0047 | 0.0078 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0185 | 0.0611 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0047 | 0.0078 |
Mycobacterium tuberculosis | Probable reductase | 0.018 | 0.3554 | 0.3416 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0368 | 0.0236 |
Onchocerca volvulus | 0.0077 | 0.1419 | 0.2658 | |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0231 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0154 | 0.302 | 0.5003 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0047 | 0.0155 |
Plasmodium vivax | glutathione reductase, putative | 0.0079 | 0.146 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0079 | 0.146 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0123 | 0.2377 | 0.3938 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0077 | 0.1419 | 0.1235 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0504 | 0.0836 |
Entamoeba histolytica | hypothetical protein | 0.0154 | 0.302 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0047 | 0.0078 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0047 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0112 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1419 | 0.235 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.1419 | 0.235 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.1419 | 0.1235 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0368 | 0.061 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0047 | 0.0155 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0185 | 0.0306 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0047 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0368 | 0.061 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0185 | 0.0306 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.0368 | 0.0236 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0185 | 0.0611 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0156 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0185 | 0.0306 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0027 | 0.0392 | 0.0222 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0185 | 0.0611 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.06 | 0.0995 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0047 | 0.0078 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.06 | 0.0995 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0047 | 0.0078 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0042 | 0.0687 | 0.2759 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.1419 | 0.1818 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0443 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0047 | 0.0078 |
Echinococcus multilocularis | musashi | 0.003 | 0.0443 | 0.1466 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0047 | 0.0078 |
Schistosoma mansoni | hypothetical protein | 0.0154 | 0.302 | 0.5003 |
Trichomonas vaginalis | esterase, putative | 0.0077 | 0.1419 | 0.1818 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0047 | 0.0078 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0185 | 0.0611 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0077 | 0.1419 | 0.1235 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0047 | 0.0155 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0047 | 0.0078 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0027 | 0.0392 | 0.1299 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0027 | 0.0392 | 0.0278 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0047 | 0.0078 |
Schistosoma mansoni | glutaminase | 0.03 | 0.6037 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.03 | 0.6037 | 1 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.002 | 0.0242 | 0.0401 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.0959 | 0.1588 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0504 | 0.167 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0047 | 0.0078 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0047 | 0.0078 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.1419 | 0.1235 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0079 | 0.146 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0027 | 0.0392 | 0.0222 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0368 | 0.061 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0047 | 0.0155 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0047 | 0.0078 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0047 | 0.0078 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0027 | 0.0392 | 0.1312 |
Brugia malayi | beta-lactamase | 0.0077 | 0.1419 | 0.235 |
Echinococcus granulosus | lamin | 0.003 | 0.0443 | 0.1466 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0504 | 0.2223 |
Entamoeba histolytica | hypothetical protein | 0.0154 | 0.302 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0027 | 0.0392 | 0.1312 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0027 | 0.0392 | 0.0278 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0047 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0368 | 0.061 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.1419 | 0.1818 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0077 | 0.1419 | 0.1235 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.018 | 0.3554 | 0.8845 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.0368 | 0.0163 |
Leishmania major | trypanothione reductase | 0.0079 | 0.146 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.1419 | 0.961 |
Schistosoma mansoni | thyroid hormone receptor | 0.0144 | 0.2797 | 0.4633 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0443 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.06 | 0.0995 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0042 | 0.0687 | 0.0522 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0047 | 0.0155 |
Onchocerca volvulus | 0.003 | 0.0443 | 0.0767 | |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0047 | 0.0155 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0027 | 0.0392 | 0.0278 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0079 | 0.146 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0079 | 0.146 | 0.1278 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0047 | 0.0078 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0047 | 0.0078 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.2672 | 0.8846 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0047 | 0.0078 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0047 | 0.0078 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.