Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.2863 | 0.183 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.7967 | 0.7673 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0851 | 0.0678 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.7967 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.7332 | 0.9167 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0025 | 0.1461 | 0.1579 |
Schistosoma mansoni | flap endonuclease-1 | 0.0023 | 0.1025 | 0.0906 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.3611 | 0.3902 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.4024 | 0.4348 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.3186 | 0.3737 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.7967 | 0.7673 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0025 | 0.1461 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.2863 | 0.3313 |
Schistosoma mansoni | bromodomain containing protein | 0.0061 | 0.7956 | 0.9985 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.5614 | 0.4979 |
Brugia malayi | RNA binding protein | 0.0061 | 0.7967 | 0.7673 |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.7967 | 1 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0025 | 0.1461 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.7967 | 0.861 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0851 | 0.0678 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.7967 | 0.861 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.7967 | 1 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0518 | 0.0241 |
Entamoeba histolytica | Flap nuclease, putative | 0.0025 | 0.1461 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.4357 | 0.4709 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0518 | 0.0559 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0025 | 0.1461 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.7332 | 0.9167 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0025 | 0.1461 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.7967 | 0.861 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.9254 | 1 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0025 | 0.1461 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.7967 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.7967 | 1 |
Brugia malayi | Flap endonuclease-1 | 0.0025 | 0.1461 | 0.0226 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.5614 | 0.6066 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0025 | 0.1461 | 0.5 |
Plasmodium falciparum | flap endonuclease 1 | 0.0025 | 0.1461 | 0.5 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0025 | 0.1461 | 0.1477 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.7967 | 1 |
Echinococcus granulosus | flap endonuclease 1 | 0.0025 | 0.1461 | 0.1477 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.5614 | 0.6066 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.7967 | 1 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0025 | 0.1461 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.5614 | 0.4979 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.3599 | 0.2673 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.3186 | 0.3737 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0851 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2863 | 0.3093 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.