Detailed information for compound 1025054

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 436.502 | Formula: C21H32N4O6
  • H donors: 4 H acceptors: 5 LogP: -1.98 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCCCC[C@@H](C(=O)O)NC(=O)COc1ccc(cc1)C1=[N+]([O-])C(C(N1O)(C)C)(C)C
  • InChi: 1S/C21H32N4O6/c1-20(2)21(3,4)25(30)18(24(20)29)14-8-10-15(11-9-14)31-13-17(26)23-16(19(27)28)7-5-6-12-22/h8-11,16,29H,5-7,12-13,22H2,1-4H3,(H,23,26)(H,27,28)/t16-/m0/s1
  • InChiKey: QTPMYFXGFVRXKJ-INIZCTEOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum thioredoxin reductase 0.0019 0.0365 0.1826
Loa Loa (eye worm) hypothetical protein 0.0029 0.0845 0.0845
Loa Loa (eye worm) heterochromatin protein 1 0.0066 0.2562 0.2562
Onchocerca volvulus Alhambra homolog 0.0028 0.078 0.078
Echinococcus multilocularis chromobox protein 1 0.0066 0.2562 0.2562
Loa Loa (eye worm) solute carrier family 6 member 4 0.0226 1 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0123 0.5201 0.8837
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0714 0.2789
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0365 0.1562
Plasmodium falciparum amino acid transporter, putative 0.0038 0.1281 0.6412
Brugia malayi jmjC domain containing protein 0.0033 0.105 0.105
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0011 0.00000000017963 0.00000000017963
Mycobacterium tuberculosis Probable oxidoreductase 0.0136 0.5837 1
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0554 0.0554
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0038 0.1281 0.1281
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0037 0.1216 0.1216
Schistosoma mansoni chromobox protein 0.0066 0.2562 0.2562
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0365 0.1562
Toxoplasma gondii hypothetical protein 0.0038 0.1281 0.4731
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.2709 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.00000000017963 0.00000000017963
Plasmodium falciparum glutathione reductase 0.0019 0.0365 0.1826
Echinococcus granulosus peregrin 0.0028 0.078 0.078
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.4016 0.4016
Toxoplasma gondii thioredoxin reductase 0.0054 0.1998 0.7378
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0365 0.1562
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0554 0.2163
Loa Loa (eye worm) norepinephrine transporter 0.0226 1 1
Entamoeba histolytica hypothetical protein 0.0041 0.1401 1
Trichomonas vaginalis chromobox protein, putative 0.004 0.1346 0.5254
Brugia malayi CHD4 protein 0.0011 0.00000000017963 0.00000000017963
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.078 0.2881
Onchocerca volvulus 0.0226 1 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0365 0.1562
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0038 0.1281 0.1281
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000000017963 0.0000000012825
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.1346 0.1346
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.00000000017963 0.00000000017963
Onchocerca volvulus 0.0038 0.1281 0.1281
Loa Loa (eye worm) thioredoxin reductase 0.0054 0.1998 0.1998
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.2709 0.4283
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.4016 0.4016
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.1281 0.1281
Echinococcus granulosus chromobox protein 1 0.0066 0.2562 0.2562
Giardia lamblia PHD finger protein 15 0.0028 0.078 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Plasmodium vivax glutathione reductase, putative 0.0054 0.1998 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0655 0.328
Loa Loa (eye worm) hypothetical protein 0.0025 0.0655 0.0655
Schistosoma mansoni jumonji/arid domain-containing protein 0.0033 0.105 0.105
Entamoeba histolytica hypothetical protein 0.0041 0.1401 1
Schistosoma mansoni hypothetical protein 0.0028 0.078 0.078
Trichomonas vaginalis chromobox protein, putative 0.004 0.1346 0.5254
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.1281 0.1281
Loa Loa (eye worm) CHromoDomain protein family member 0.0011 0.00000000017963 0.00000000017963
Trichomonas vaginalis mercuric reductase, putative 0.0019 0.0365 0.1425
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.2709 1
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.1216 0.4746
Loa Loa (eye worm) hypothetical protein 0.0011 0.00000000017963 0.00000000017963
Echinococcus granulosus sodium and chloride dependent glycine 0.0038 0.1281 0.1281
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0204 0.0752
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.009 0.3696 0.3696
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0136 0.5837 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0365 0.5
Loa Loa (eye worm) hypothetical protein 0.0037 0.1216 0.1216
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0365 0.1826
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0014 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0047 0.1696 0.1696
Loa Loa (eye worm) hypothetical protein 0.0226 1 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0365 0.1143
Trichomonas vaginalis chromobox protein, putative 0.0066 0.2562 1
Loa Loa (eye worm) hypothetical protein 0.0114 0.4811 0.4811
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0062 0.0446
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.078 0.078
Brugia malayi hypothetical protein 0.0041 0.1401 0.1401
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0365 0.1562
Brugia malayi Bromodomain containing protein 0.0028 0.078 0.078
Echinococcus granulosus serotonin transporter 0.0226 1 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.4016 0.4016
Schistosoma mansoni hypothetical protein 0.0011 0.0018 0.0018
Onchocerca volvulus 0.0029 0.0845 0.0845
Plasmodium falciparum phd finger protein, putative 0.0028 0.078 0.3905
Plasmodium vivax hypothetical protein, conserved 0.0038 0.1281 0.6412
Schistosoma mansoni sodium-dependent amino acid transporter 0.0038 0.1281 0.1281
Plasmodium falciparum transporter, putative 0.0038 0.1281 0.6412
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0038 0.1281 0.1281
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.1401 0.1401
Plasmodium vivax thioredoxin reductase, putative 0.0054 0.1998 1
Entamoeba histolytica hypothetical protein 0.0041 0.1401 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.4016 0.4016
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0038 0.1281 0.1281
Echinococcus multilocularis sodium and chloride dependent glycine 0.0038 0.1281 0.1281
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.1281 0.1281
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.009 0.3696 0.3696
Schistosoma mansoni jumonji domain containing protein 0.0072 0.2834 0.2834
Echinococcus granulosus Chromo domain 0.0011 0.00000000017963 0.00000000017963
Loa Loa (eye worm) hypothetical protein 0.0038 0.1281 0.1281
Brugia malayi hypothetical protein 0.0016 0.0245 0.0245
Schistosoma mansoni hypothetical protein 0.0041 0.1401 0.1401
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0038 0.1281 0.1281
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0655 0.242
Trypanosoma brucei trypanothione reductase 0.0054 0.1998 1
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0655 0.328
Loa Loa (eye worm) hypothetical protein 0.0226 1 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.0038 0.1281 0.1281
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0655 0.3063
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0365 0.1562
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.078 0.078
Echinococcus granulosus bloom syndrome protein 0.0023 0.0554 0.0554
Leishmania major hypothetical protein, conserved 0.0025 0.0655 0.2241
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.1281 0.4731
Brugia malayi hypothetical protein 0.0025 0.0655 0.0655
Brugia malayi jmjC domain containing protein 0.009 0.3696 0.3696
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0014 0.0135 0.0135
Loa Loa (eye worm) RecQ helicase 0.0023 0.0554 0.0554
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.4016 0.4016
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0426 0.2131
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0018 0.0018
Echinococcus multilocularis jumonji domain containing protein 0.0038 0.1282 0.1282
Brugia malayi Thioredoxin reductase 0.0054 0.1998 0.1998
Leishmania major trypanothione reductase 0.0054 0.1998 0.7316
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0038 0.1281 0.1281
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0655 0.3063
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0365 0.1562
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000000017963 0.0000000012825
Plasmodium vivax amine transporter, putative 0.0038 0.1281 0.6412
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.1281 0.1281
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.4016 0.4016
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0038 0.1281 0.1281
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0365 0.0365
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0123 0.5201 0.8837
Plasmodium vivax hypothetical protein, conserved 0.0011 0.00000000017963 0.00000000089888
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0365 0.1143
Loa Loa (eye worm) hypothetical protein 0.0226 1 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.1281 0.4731
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0018 0.0018
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0123 0.5201 0.8837
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0365 0.1347
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.1281 0.1281
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0038 0.1281 0.1281
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.1216 0.4746
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0212 0.1062
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0226 1 1
Loa Loa (eye worm) glutathione reductase 0.0054 0.1998 0.1998
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0365 0.1562
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0038 0.1281 0.1281
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000000017963 0.0000000012825
Mycobacterium tuberculosis Probable dehydrogenase 0.0123 0.5201 0.8837
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.1401 0.1401
Echinococcus multilocularis thioredoxin glutathione reductase 0.0054 0.1998 0.1998
Echinococcus granulosus chromobox protein 1 0.0066 0.2562 0.2562
Trichomonas vaginalis glutathione reductase, putative 0.0019 0.0365 0.1425
Echinococcus multilocularis lysine specific demethylase 5A 0.0033 0.105 0.105
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0365 0.1826
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Echinococcus multilocularis Chromo domain 0.0011 0.00000000017963 0.00000000017963
Brugia malayi PHD-finger family protein 0.0028 0.078 0.078
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0365 0.1826
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.4016 0.4016
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.2709 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0054 0.1998 0.2985
Loa Loa (eye worm) hypothetical protein 0.0038 0.1281 0.1281
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0123 0.5201 0.8837
Schistosoma mansoni sodium/chloride dependent transporter 0.0038 0.1281 0.1281
Loa Loa (eye worm) hypothetical protein 0.0038 0.1281 0.1281
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0136 0.5837 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0365 0.1143
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.2709 0.2709
Schistosoma mansoni sodium/chloride dependent transporter 0.0226 1 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.1401 0.1401
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0038 0.1281 0.1281
Brugia malayi glutathione reductase 0.0054 0.1998 0.1998
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0062 0.0244
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.2709 0.2709
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0554 0.2163
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0365 0.0365
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.105 0.105
Loa Loa (eye worm) serotonin transporter b 0.0226 1 1
Onchocerca volvulus 0.0038 0.1281 0.1281
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.078 0.078
Echinococcus multilocularis peregrin 0.0028 0.078 0.078
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0365 0.1143
Loa Loa (eye worm) hypothetical protein 0.0038 0.1281 0.1281
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.00000000017963 0.00000000066318
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.1281 0.1281
Loa Loa (eye worm) hypothetical protein 0.0038 0.1281 0.1281
Schistosoma mansoni sodium/chloride dependent transporter 0.0038 0.1281 0.1281
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0365 0.1562
Brugia malayi chromobox protein homolog 3 0.0037 0.1216 0.1216
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0332 0.0332
Echinococcus granulosus sodium and chloride dependent glycine 0.0038 0.1281 0.1281
Echinococcus multilocularis chromobox protein 1 0.0066 0.2562 0.2562
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0655 0.328
Loa Loa (eye worm) jmjC domain-containing protein 0.0057 0.2145 0.2145
Loa Loa (eye worm) hypothetical protein 0.0038 0.1281 0.1281
Entamoeba histolytica hypothetical protein 0.0041 0.1401 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.0038 0.1281 0.1281
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.00000000017963 0.00000000017963
Trichomonas vaginalis chromobox protein, putative 0.0066 0.2562 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0365 0.1562
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.4016 0.4016
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0365 0.1826
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.1281 0.1281
Entamoeba histolytica hypothetical protein 0.0011 0.00000000017963 0.0000000012825
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0365 0.1347
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0365 0.5
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.4016 0.4016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0714 0.2789
Schistosoma mansoni hypothetical protein 0.0011 0.00000000017963 0.00000000017963
Echinococcus granulosus thioredoxin glutathione reductase 0.0054 0.1998 0.1998
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.1281 0.1281
Schistosoma mansoni jumonji/arid domain-containing protein 0.0033 0.105 0.105
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.078 0.2881
Echinococcus multilocularis serotonin transporter 0.0226 1 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.2709 0.2709
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0365 0.0365
Mycobacterium tuberculosis Probable reductase 0.0123 0.5201 0.8837
Treponema pallidum sodium- and chloride- dependent transporter 0.0226 1 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0365 0.1562
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0365 0.0365
Schistosoma mansoni chromobox protein 0.0066 0.2562 0.2562
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.1281 0.1281
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.00000000017963 0.00000000089888
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.078 0.078
Plasmodium falciparum thioredoxin reductase 0.0054 0.1998 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.2709 0.2709
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0655 0.3063
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0136 0.5837 1
Onchocerca volvulus 0.0038 0.1281 0.1281
Plasmodium falciparum glutathione reductase 0.0054 0.1998 1
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0011 0.00000000017963 0.00000000017963
Echinococcus granulosus jumonji domain containing protein 0.0038 0.1282 0.1282
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0038 0.1281 1
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.00000000017963 0.00000000017963
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.1281 0.4731
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0365 0.1562
Trypanosoma cruzi trypanothione reductase, putative 0.0054 0.1998 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0365 0.1562
Echinococcus granulosus lysine specific demethylase 5A 0.0033 0.105 0.105
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0038 0.1281 0.1281
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.00000000017963 0.00000000070125
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0554 0.0554
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.2709 1
Plasmodium vivax hypothetical protein, conserved 0.0028 0.078 0.3905
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0038 0.1281 0.1281
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.00000000017963 0.00000000017963
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.2709 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.00000000017963 0.00000000017963
Brugia malayi Heterochromatin protein 1 0.0066 0.2562 0.2562
Toxoplasma gondii hypothetical protein 0.0038 0.1281 0.4731
Brugia malayi hypothetical protein 0.0038 0.1281 0.1281

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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